Reduced functional independence and multimorbidity increases the risk of severe infection among older patients with Omicron: a multicenter retrospective cohort study by Wan Yu, Runnian Huang, Shuning Sun, Li Bu, Xin Chen, Yunhua Di, Shuwu Lin, Qian Li, Yang Yang, Xingyue Ye, Wenxu Wang, Rui Ren, Linze Xi, Ru Zhang, Yi Li, Xin Li, Tianbo Hou, Zibo Ning, Yang Peng, Difei Wang

“…Compared to non-multimorbid patients (OR = 3.71, 95% CI: [1.58, 9.16]), multimorbid patients (OR = 10.04, 95% CI: [5.63, 18.57]) had a more pronounced risk of severe or critical infection. …”
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TOPBP1 as a potential predictive biomarker for enhanced combinatorial efficacy of olaparib and AZD6738 in PDAC by Xiao-Mei Tang, Min-Min Shi, Jia-Cheng Wang, Yi-Jin Gu, Yu-Ting Dai, Qin-Xin Yang, Jia Liu, Ling-Jie Ren, Xin-Yun Liu, Chun Yang, Fang-Fang Ma, Ji-Bing Liu, Hong Yu, Da Fu, Yun-Feng Wang

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Application of deep learning models on single-cell RNA sequencing analysis uncovers novel markers of double negative T cells by Tian Xu, Qin Xu, Ran Lu, David N. Oakland, Song Li, Liwu Li, Christopher M. Reilly, Xin M. Luo

“…Abstract Double negative T (DNT) cells are a unique subset of CD3 + TCRαβ + T lymphocytes that lack CD4, CD8, or NK1.1 expression and constitute 3–5% of the total T cell population in C57BL/6 mice. …”
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Exploring correlations between Conners’ Continuous Performance Test and subjective measures of attention deficit hyperactivity disorder symptoms in a paediatric clinical sample by Xue Wei Wendy Poh, Shernice Shi Yun Lim, Ying Yin Chew, Nikki Shi Jie Lim-Ashworth, Choon Guan Lim

“…Methods: The data, gathered from a large-scale randomised controlled trial involving 172 children aged 6–12 years with ADHD, was pooled, and a Pearson correlation analysis was conducted. …”
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Spatiotemporal Variations of PM2.5 and O3 Relationship during 2014–2021 in Eastern China by Yasong Li, Tijian Wang, Qin’geng Wang, Yawei Qu, Hao Wu, Min Xie, Mengmeng Li, Shu Li, Bingliang Zhuang

“…Based on our investigations, it was found that the yearly average level of PM2.5 presented a consistent diminish, falling from 55.8 µg m−3 (2014) to 31.9 µg m−3 (2021), while O3 increased by 7.2% during 2014–2017 but decreased by 1.9% in 2018–2021. …”
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The relationship between negative psychological state and quality of life among cardiovascular disease patients in China: the masking effect of abnormal dietary behavior by QingNing Chang, QingNing Chang, HaiBo Ma, Can Zhang, Xin Li, YiBo Wu, LiNa Ha

“…All data were analyzed using SPSS Statistics 23.0.Results(1) Depression was negatively associated with QoL (r = −0.386/−0.230, p < 0.001), and was positively correlated with abnormal dietary behavior (r = 0.377, p < 0.001). …”
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Effects of Biogas Slurry Drip Irrigation on Growth Performance of Brassica chinensis L. and Soil Nutrient Dynamics by DongXue Yin, Jiajun Qin, Dongdong Chen, Baozhong Wang, Wei Liu, Yingxian Wang, Weijuan Lan, Zhihao Wang, Jiachen Wang

“…An experiment was set up with six sets of drip irrigation gradients (1:3 mix of biogas and water) of 12 (BS-1), 15 (BS-2), 18 (BS-3), 21 (BS-4), 24 (BS-5), and 27 (BS-6) L. …”
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X-linked ubiquitin-specific peptidase 11 (USP11) increases susceptibility to Cushing’s disease in women by Tao Zhang, Yanting Liu, Fang Liu, Kaiyu Guo, Runhua Tang, Jingwei Ye, Li Xue, Zhipeng Su, Zhe Bao Wu

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Mitigation PFHxA-induced neurotoxicity in Carassius auratus brain cells by selenium-enriched Bacillus subtilis via the BDNF/PI3K/AKT/GSK-3β pathway by Yu-ting Lu, Zheng-yao Guo, Lei Guo, Yu-hua He, Li-ming Liu, Xue Jiao, Yue-hong Li

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The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation by Kevin S. Blake, Yao-Peng Xue, Vincent J. Gillespie, Skye R. S. Fishbein, Niraj H. Tolia, Timothy A. Wencewicz, Gautam Dantas

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HACE1 protects against myocardial ischemia–reperfusion injury via inhibition of mitochondrial fission in mice by Bang-Xia Liu, Juan Zheng, Zhan-Wei Tang, Lei Gao, Meng Wang, Ying Sun, Chen Chen, Heng-Chen Yao

“…However, little is known about the role of HACE1 in the pathogenesis of myocardial I/RI. Methods Male C57BL6 mice with HACE1 knockout (KO) were subjected to 30 min of ischemia via ligation of the left anterior descending artery, followed by 0, 2, 6, or 24 h of reperfusion. …”
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Inverse association between dietary flavonoid intake and nocturia in middle-aged and older adults from NHANES 2007–2010 by Yu Cai, Ying-Chao Liang, Xin-Yu Hu, Ling Li, De-Liang Liu, Shu-Fang Chu, Hui-Lin Li

“…After fully adjusting for confounders, weighted logistic regression models indicated that dietary flavonoid intake was significantly associated with a decreased prevalence of nocturia (OR: 0.93; 95% CI: 0.88-1.00, P-value = 0.036). This trend remained significant in the analysis stratified by quartile level of flavonoid intake. …”
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The application of emerging technologies for the quality and safety evaluation of oilseeds and edible oils by Xue Li, Wenwen Liu, Lu Xiao, Jie Zhao, Yan Chen, Liangxiao Zhang, Peiwu Li, Dolores Pérez-Marín, Xu Wang

“…Food Chemistry: X…”
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The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospe... by Nuo Xu, Jian-Xin Zhang, Jia-Jie Zhang, Zhuo Huang, Lian-Chun Mao, Zhi-Yong Zhang, Wei-Dong Jin

“…Conclusion Preoperative NLR and PLR can predict the long-term prognosis of colorectal cancer (CRC) and CAL patients, and patients with NLR ≥ 2.89 and PLR ≥ 157.62 have poor survival prognosis. …”
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Educate to Detect: Conducting First Detector Training in Florida by Amanda Hodges, Jennifer Gillett-Kaufman, Carrie Harmon, Aaron Palmateer, Pamela Roberts, Adrian Hunsberger, Sylvia Shives, Theresa Friday, Jiannong Xin

Subjects: “…IN788…”
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Association of per- and polyfluoroalkyl substances with gout risk: a cross-sectional analysis of NHANES 2007–2018 data emphasizing mixture effects by Haixin Feng, Siran Li, Shiqing Huang, Linxi He, Ruihao Huang, Renhuizi Wei, Xin Peng, Haiyi Yan, Chongxiang Xiong, Bingsong Zhang

“…And assessing the potential intermediary effect of uric acid.MethodsThe study included 8,494 participants, with 385 having gout. Four PFAS compounds (PFOA, PFOS, PFHxS, PFNA) were measured. …”
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Retiming dynamics of harmonically mode-locked laser solitons in a self-driven optomechanical lattice by Xiaocong Wang, Benhai Wang, Wenbin He, Xintong Zhang, Qi Huang, Zhiyuan Huang, Xin Jiang, Meng Pang, Philip. St. J. Russell

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Left atrial strain predicts paroxysmal atrial fibrillation recurrence after catheter ablation: a 1-year study using three-dimensional speckle-tracking echocardiography by Rui Zhang, He Li, Yan Wang, Tianle Yu, Jiacheng Li, Yumeng Wu, Zhiwen Yu, Cuixing Liang, Dan Yu, Li Xue

“…Receiver operating characteristic(ROC) curve showed that the area under the curve(AUC) for LASr in assessing the risk of recurrence after RFCA in patients with PAF was 0.70 ( 95% CI, 0.60–0.81, P = 0.001). The calculated cutoff value was 16.5%. …”
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