Effect of a prepartum and postpartum, complex interdisciplinary lifestyle and psychosocial intervention on metabolic and mental health outcomes in women with gestational diabetes m... by Umberto Simeoni, Antje Horsch, Arnaud Chiolero, Yvan Vial, Nicole Sekarski, Jardena J Puder, Pascal Bovet, Yvan Mivelaz, Adina Mihaela Epure, Bobby Stuijfzand, Leah Gilbert, Stefano Lanzi, Justine Gross, Didier Hans, Stefano Di Bernardo, Elena Gonzalez-rodriguez, Alain Lacroix, Jean-Benoît Rossel, Dan Yedu Quansah, Amar Arhab, Sandrine Estoppey Younes, Seyda Mayerat

“…Assessors were blinded to primary and secondary outcomes.Results 84 (80%) of 105 women in the intervention and 95 (90%) of 106 in the usual care completed the study. …”
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S’approprier, c’est résister. Appropriations spatiales et mobilisation infra-politique des femmes en immobilité résidentielle et sociale dans les bidonvilles de Salé (Maroc)... by Myriame Ali-Oualla

“…Through the use of data collected during semi-structured interviews and on-site observations and surveys, I highlight the appropriation strategies mobilised to overcome this condition of inertia and to exert pressure for a suitable housing solution. The study of women’s sub-political forms of resistance in three shantytowns in the Sidi Moussa district (Salé), and the varied outlets that result from similar strategies, pushes us not only to explore the emancipatory potential of these struggles but also to further unravel the imbalance of power between the established system and the dominated groups.…”
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Genetic Polymorphisms in RNF138, ABCA1 and ESRRG-GPATCH2 Genes and their Role in Insulin Resistance Risk among Normal BMI Individuals in Indian Population: A Case-control Study by Sabitha Thummala, Sarah Fathima, Nithya Kruthi, Junaid Ahmed Khan Ghori, Katherine Saikia, Vivek Belde, Balamurali Andiyakkal Rajendran, Rahul Ranganathan

“…Despite the growing prevalence, the genetic underpinnings of Insulin Resistance (IR) among Indians with a normal Body Mass Index (BMI) remains understudied. …”
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Evaluating the use of Uromune® autovaccine in recurrent urinary tract infections: a pilot unicenter retrospective study in Reus, Spain by Simona Iftimie, Paula Ladero-Palacio, Ana F. López-Azcona, Laia Pujol-Galarza, Antoni Pont-Salvadó, Xavier Gabaldó-Barrios, Jorge Joven, Jordi Camps, Antoni Castro, Mercè Pascual-Queralt

“…Abstract Background Urinary tract infections (UTIs) are a significant global health issue, especially among women, with growing concerns related to antibiotic resistance and adverse effects. …”
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Impact of dapagliflozin on metabolic phenotype, hormone levels, and fertility in female mice after prolonged high-fat diet by Xiaolin Chen, Zhuoni Xiao, Na Dai, Mingxia Fan

“…The sodium-glucose cotransporter 2 inhibitors (SGLT2i) have emerged as a treatment for type 2 diabetic patients, regulating adipose tissue metabolism, hypothalamic inflammation, and ovulation in women with polycystic ovary syndrome (PCOS). The study aimed to investigate the pharmacological effects of dapagliflozin on improving insulin resistance, energy metabolism, sex hormones, and fertility in female mice following prolonged consumption of HFD.MethodsAt 6 weeks of age, female mice were fed a HFD and treated with dapagliflozin. …”
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Woxuanzhongzhou formula improves DHEAS and high-fat diet-induced IR and anovulatory mice via AMPK/PGC1- α/Irisin pathway by Haijuan Liu, Guohua Wang, Conglu Sui, Yanan Guo, Xiangyu He

“…Abstract Background Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder in women of reproductive age. Anovulation is one of the most important clinical features of PCOS, and insulin resistance (IR) is one of the critical pathogenic factors. …”
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Sex-specific associations between estimated glucose disposal rate and cognitive decline in middle-aged and older adults in China: a longitudinal cohort study by Chun Luo, Shuang Han, Xiaoying Shen, Hao Wu, Jianqing Zhou, Bingyang Liu

“…Similar patterns were found for episodic memory and executive function, with significant associations predominantly in females.ConclusionHigher eGDR was significantly associated with slower cognitive decline, particularly among women. These findings underscore the potential of eGDR as a marker for identifying and mitigating cognitive decline and highlight the importance of sex-specific strategies to address insulin resistance and promote cognitive health.…”
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Hypoxia Enhances HIF1α Transcription Activity by Upregulating KDM4A and Mediating H3K9me3, Thus Inducing Ferroptosis Resistance in Cervical Cancer Cells by Jing Xiong, Meifang Nie, Chun Fu, Xiaoshan Chai, Yongjing Zhang, Ling He, Shujuan Sun

“…Cervical cancer (CC) is a prevalent cancer in women. Hypoxia plays a critical role in CC cell ferroptosis resistance. …”
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Discussions on antibiotic therapy and systemic enzyme therapy for pelvic inflammatory disease: A review by Natalia M. Podzolkova, Igor E. Fadeev, Roman E. Kuznetsov, Tatiana N. Poletova

“…Pelvic inflammatory disease in women is one of the most important public health problems worldwide. …”
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Effect of Low Dose Aspirin in Low Risk Pregnant Ladies with Abnormal Uterine Artery Doppler Results, and the Evaluation of Maternal and Fetal outcomes: A Randomized Clinical Trial by Parzhin Jalal Ali, Chro Najmaddin Fattah

“…Conclusion: Doppler study of the uterine artery at 16 weeks or higher in low risk pregnant women appears to be useful as a screening test and low dose of aspirin therapy at early stage of pregnancy will decrease the incidence of preeclampsia.   …”
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PAX6 enhances Nanog expression by inhibiting NOTCH signaling to promote malignant properties in small cell lung cancer cells by Xiao-Fang Guo, Ling-Ling Wang, Fei-Meng Zheng, He-Ping Li

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AGD1/USP10/METTL13 complexes enhance cancer stem cells proliferation and diminish the therapeutic effect of docetaxel via CD44 m6A modification in castration resistant prostate can... by Hong Wang, Chunli Cui, Weiyi Li, Hui Wu, Jianjun Sha, Jiahua Pan, Wei Xue

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Establishing normal range of fetal renal artery RI and PI values in singleton pregnancies during 18-38 weeks of gestation by Beenish Nadeem, Naushaba Malik, Anam Zahoor

“…METHODOLOGY: This is a nonprobability convenient study investigating 130 healthy pregnant women during 18-38weeks of gestation. Resistivity and pulsatility indices (RI and PI) of the fetal renal arteries were evaluated dividing the patients in four groups as per their gestational age. …”
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Decreased Levels of Insulin-Regulated Aminopeptidase (IRAP) in Gestational Diabetes Mellitus: A Prospective Cohort Study by Osman Köse, Koray Gök, Elif Köse, Sezen Irmak Gözükara, Abdullah Tüten, Mehmet Sühha Bostancı

“…Serum IRAP levels are strongly associated with type 2 diabetes and insulin resistance. The aim of this study was to evaluate the IRAP level as a potential biomarker for the early diagnosis and management of insulin resistance in women with gestational diabetes mellitus (GDM). …”
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The Role of the Liver in the Pathophysiology of PCOS: A Literature Review by Abrar Alhermi, Heather Perks, Varsha Nigi, Noor Altahoo, Stephen L. Atkin, Alexandra E. Butler

“…Women with PCOS commonly have insulin resistance, increased susceptibility to type 2 diabetes mellitus, dyslipidemia, hyperinsulinemia, increased cardiovascular risk, hepatic steatosis, infertility, and an overall reduction in physical and psychological well-being. …”
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A Case–Control Study of the Association of Novel Androgens (11-KT and DHT), Classical Androgens (Testosterone and DHEAS), Hormones (LH, FSH, 17-OHP, Insulin, and SHBG), Insulin Res... by Nirmal Kumar, Neera Sharma, Smita Roy, Indu Chawla, Lokesh Kumar Sharma

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Association of TCF7L2 genetic variants rs12255372 and rs7903146 with the polycystic ovary syndrome risk: systematic review and meta-analysis by Idrees A. Shah, Rabiya Rashid, Haroon Rashid, Abid Bhat, Mohd Ashraf Ganie

“…Results The genotypic data from 3052 controls and 2291 women with PCOS from ten published studies were analysed. …”
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Triglyceride-glucose index: carotid intima-media thickness and cardiovascular risk in a European population by Chiara Pavanello, Massimiliano Ruscica, Sofia Castiglione, Giuliana Germana Mombelli, Antonia Alberti, Laura Calabresi, Cesare Riccardo Sirtori

“…Participants were generally non-obese, with an average BMI of 24.6 ± 3.5 Kg/m2. Among the women, 83.1% were postmenopausal. The mean TyG index was 8.65 ± 0.59. …”
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Update on the therapeutic role of metformin in the management of polycystic ovary syndrome: Effects on pathophysiologic process and fertility outcomes by Kerstin MG Brand, Ulrike Gottwald-Hostalek, Aimee Andag-Silva

“…A combination of metformin with clomifene citrate (another widely used treatment for PCOS) is more effective than either alone and is a useful option in women with clomifene-resistant PCOS. Combining metformin with letrozole (1st-line agent for ovulation induction in women with PCOS and no other infertility risk factors) is not more effective than letrozole alone. …”
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EMA/CO Combination Chemotheraphy in Gestational Trophoblastic Neoplasia: Update of Our Results by Tolga Taşçı, Işın Üreyen, Günsu Kimyon, Alper Karalök, Sevgi Koç, M. Faruk Köse, Gökhan Tulunay, Taner Turan

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