Healthcare-seeking pathway and delay analysis of rifampicin-resistant tuberculosis patient in Southwestern China by Yunbin Yang, Zichao Li, Liangli Liu, Jinou Chen, Ling Li, Rui Yang, Xing Yang, Lianyong Chen, Haohao Ru, Lin Xu

“…SPSS statistical software was used for descriptive statistics, nonparametric tests, and patient pathway analysis. Sankey diagram, box plot and a heat map were used for data visualization. …”
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Development and Validation of a Discrete Element Simulation Model for Pressing Holes in Sowing Substrates by Hongmei Xia, Chuheng Deng, Teng Yang, Runxin Huang, Jianhua Ou, Lingjin Dong, Dewen Tao, Long Qi

“…The angle of repose measured by the funnel method was served as the target, Plackett–Burman experiments were conducted to screen significant contact mechanical parameters, while steepest ascent and Box–Behnken experiments were employed to define their value ranges. …”
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Etiologies of excessive gingival display in a Saudi population by Reham AL Jasser, Rand AlSaif, Loulwah AlSohaim, Raghad Baidas, Faiza AL AlOtibi, Reem Andijani

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Targeting Amyloid Pathology in Early Alzheimer’s: The Promise of Donanemab-Azbt by Nadia Khartabil, Ayda Awaness

“…Key results included a 35% slowing of decline on the Integrated Alzheimer’s Disease Rating Scale (iADRS) and a 36% slowing on the Clinical Dementia Rating-Sum of Boxes (CDR-SB). Additional secondary outcomes showed improvements in activities of daily living and reduced risk of disease progression. (3) TRAILBLAZER-ALZ 3: This ongoing trial is evaluating donanemab’s potential in delaying or preventing Alois Alzheimer in cognitively normal individuals with amyloid plaques, broadening the scope of early intervention strategies. (4) TRAILBLAZER-ALZ 4: A head-to-head comparison with aducanumab revealed superior amyloid plaque clearance with donanemab. (5) TRAILBLAZER-ALZ 5: Currently recruiting, this trial aims to evaluate safety and efficacy across diverse populations with varying tau levels and comorbidities. (6) TRAILBLAZER-ALZ 6 (Phase 3b): This trial investigates modified dosing regimens to reduce ARIA while maintaining efficacy, particularly in populations with genetic risk factors like ApoE ε4 homozygotes. …”
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First study of single-event burnout in very-thin planar silicon sensors by Marco Ferrero, Roberta Arcidiacono, Roberta Arcidiacono, Nicolò Cartiglia, Leonardo Lanteri, Leonardo Lanteri, Luca Menzio, Luca Menzio, Arianna Morozzi, Francesco Moscatelli, Francesco Moscatelli, Roberto Mulargia, Federico Siviero, Robert White, Valentina Sola, Valentina Sola

“…This frame was placed inside a cold box to operate the irradiated sensors at very high electric fields while keeping their leakage current low. …”
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Climate Change‐Driven Heatwaves Pose Lethal Risks to Newborn Forest Bats by Danilo Russo, Anne Mäenurm, Luca Cistrone, Adriano Martinoli, Greta Foiani, Valentina Giongo, Stefania Leopardi

“…Temperature extremes can cause high physiological stress in animals, particularly in species or life stages with limited thermoregulatory abilities. While available evidence pertains to flying foxes and bats using bat boxes or dwelling in urban environments, heatwave‐induced mortality in forest‐dwelling species in temperate forests has not been reported. …”
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Cannabis legalization and cannabis use disorder in United States Veterans Health Administration patients with and without psychiatric disorders, 2005–2022: a repeated cross-section... by Deborah S. Hasin, Carol Malte, Melanie M. Wall, Daniel Alschuler, Tracy L. Simpson, Mark Olfson, Ofir Livne, Zachary L. Mannes, David S. Fink, Katherine M. Keyes, Magdalena Cerdá, Charles C. Maynard, Salomeh Keyhani, Silvia S. Martins, Scott Sherman, Andrew J. Saxon

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Microneedle Delivery of Heterologous Microparticulate COVID-19 Vaccine Induces Cross Strain Specific Antibody Levels in Mice by Tanisha Manoj Arte, Smital Rajan Patil, Emmanuel Adediran, Revanth Singh, Priyal Bagwe, Mahek Anil Gulani, Dedeepya Pasupuleti, Amarae Ferguson, Susu M. Zughaier, Martin J. D’Souza

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Harnessing <i>Trichoderma</i> spp.: A Promising Approach to Control Apple Scab Disease by Safae Gouit, Ismahane Chair, Zineb Belabess, Ikram Legrifi, Khadija Goura, Abdessalem Tahiri, Abderrahim Lazraq, Rachid Lahlali

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Bangladeshi Vehicle Classification and Detection Using Deep Convolutional Neural Networks With Transfer Learning by Farid, Proshanta Kumer Das, Monirul Islam, Ebna Sina

“…Next, we have customised the LabelImg image annotation tool to improve the following features: (a) Changing Label Font &#x0026; Border, (b) Detecting Incorrect Labels, (c) Abbreviating Label Names, (d) Improving Crosshair &#x0026; Bounding Box Guide, (e) Adding Progress Information, and (f) Improving File List Panel. …”
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Can machine-learning algorithms improve upon classical palaeoenvironmental reconstruction models? by P. Sun, P. B. Holden, H. J. B. Birks, H. J. B. Birks

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A Self-Adaptive Serious Game to Improve Motor Learning Among Older Adults in Immersive Virtual Reality: Short-Term Longitudinal Pre-Post Study on Retention and Transfer by Gauthier Everard, Louise Declerck, Thierry Lejeune, Martin Gareth Edwards, Justine Bogacki, Cléo Reiprich, Kelly Delvigne, Nicolas Legrain, Charles Sebiyo Batcho

“…The evaluation included iVR tests such as KinematicsVR and a VR adaptation of the Box and Block Test (BBT-VR). …”
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BED-YOLO: An Enhanced YOLOv10n-Based Tomato Leaf Disease Detection Algorithm by Qing Wang, Ning Yan, Yasen Qin, Xuedong Zhang, Xu Li

“…All images were annotated with bounding boxes, and the class distribution was relatively balanced to ensure the stability of training and the fairness of evaluation. …”
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Fabrication and In Vivo Evaluation of In Situ pH-Sensitive Hydrogel of Sonidegib–Invasomes via Intratumoral Delivery for Basal Cell Skin Cancer Management by Maha M. Ghalwash, Amr Gamal Fouad, Nada H. Mohammed, Marwa M. Nagib, Sherif Faysal Abdelfattah Khalil, Amany Belal, Samar F. Miski, Nisreen Khalid Aref Albezrah, Amani Elsayed, Ahmed H. E. Hassan, Eun Joo Roh, Shaimaa El-Housiny

“…Methods: Numerous S-INV formulations were developed using Box–Behnken Design Expert and tested before settling on the optimum S-INV formulation. …”
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Automatic Correction of Labeling Errors Applied to Tomato Detection by Ángel Eduardo Zamora Suárez, Gerardo Antonio Alvarez Hernandez, Juan Irving Vasquez, Hind Taud, Abril Valeria Uriarte-Arcia, Erik Zamora

“…These results demonstrate that the model was able to detect more true positives after filtering, while also achieving more accurate bounding box predictions. …”
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Working memory related functional connectivity in adult ADHD and its amenability to training: A randomized controlled trial by Tuija Tolonen, Sami Leppämäki, Timo Roine, Kimmo Alho, Pekka Tani, Anniina Koski, Matti Laine, Juha Salmi

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Characterising developmental dynamics of adult epigenetic clock sitesResearch in context by Rosa H. Mulder, Alexander Neumann, Janine F. Felix, Matthew Suderman, Charlotte A.M. Cecil

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Feasibility and preliminary efficacy of an online home-based functional exercise program for Parkinson's disease: a pilot study by Hyungwoo Lee, Hunyoung Ha, Heehyun Shin, Byungjun Park, Nyeonju Kang, Kiwon Park, Ryul Kim, Kyeongho Byun

“…The exercise regimen included softball, bodyweight, elastic band, and step box exercises targeting muscle strength, balance, and mobility. …”
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Incorporation of SWAT & WEAP models for analysis of water demand deficits in the Kala Oya River Basin in Sri Lanka: perspective for climate and land change by Sajana Pramudith Hemakumara, Thilini Kaushalya, Kamal Laksiri, Miyuru B Gunathilake, Hazi Md Azamathulla, Upaka Rathnayake

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Abstract 175: Impact of COVID‐19 on Intracranial Aneurysm Treatment and Outcomes: A Nationwide Propensity Score Matched Study. by Jorge R. Rios Zermeno, Abdul Karim A. Ghaith, Victor G. El‐Hajj, Loizos Michaelides, Rabih G. Tawk

“…Endovascular interventions were performed in 82.9% of pre‐COVID IAs admissions compared to 82.4% during the COVID period, while open surgical treatment was performed in 17.1% of pre‐COVID and 17.6% of the patients during COVID (p=0.625). …”
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