Near-infrared organic nanoparticles (6BQ NPs) enhance the random flaps survival by modulating the HSP90/HIF-1α axis through mild photothermal therapy by Feng Wu, Jin Zhang, Jiangtian Ye, Jinwu Wang, Wenhao Zheng, Hua Chen, Xiaoyu Dong, Zu-Sheng Huang, Leyi Cai, Guangheng Xiang

“…In this study, we assessed the effects of 6BQ NPs on cell viability, proliferation, migration, and angiogenesis of human umbilical vein endothelial cells (HUVECs) using MPTT in vitro. Techniques such as Cell Counting Kit-8(CCK8), wound scratch assay, Transwell assay, tube formation assay, RT-qPCR, and Western blotting were employed, along with an exploration of the related signaling mechanisms. …”
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Caryota maxima leaf extract extends Caenorhabditis elegans lifespan by inducing mono-unsaturated fatty acid accumulation via DAF-2 signaling by Zhifan Mao, Haiyan Jiang, Lingyuan Bao, Yufeng Han, Manjiong Wang, Xiaokang Li, Conglong Xia, Jian Li, Bo Han, Bei Jiang, Zelan Hu

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Taurine-Based Hybrid Drugs as Potential Anticancer Therapeutic Agents: In Vitro, In Vivo Evaluations by Saltanat Nakypova, Andrey Smolobochkin, Tanzilya Rizbayeva, Rakhymzhan Turmanov, Almir Gazizov, Nurgali Akylbekov, Rakhmetulla Zhapparbergenov, Roza Narmanova, Saltanat Ibadullayeva, Alena Zalaltdinova, Marat Syzdykbayev, Julia Voronina, Anna Lyubina, Alexandra Voloshina, Elena Klimanova, Tatiana Sashenkova, Denis Mishchenko, Alexander Burilov

“…We have synthesized 26 compounds, structures of which were confirmed using NMR, X-ray diffractometry, and other techniques. …”
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Metastasis of Squamous Cell Carcinoma of the Larynx to the Right Adrenal Gland—A Case Report by Eliza Działach, Michał Simlot, Karolina Osowiecka, Elżbieta Nowara, Jarosław Markowski, Mateusz Grajek

“…Diagnostic imaging and histopathological examination were complemented by biochemical evaluations to assess hormonal activity. …”
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Molecular interaction assays in silico of crotapotin from Crotalus durissus terrificus against the molecular target trypanothione reductase from Leishmania braziliensis by Jamile Mariano Macedo, Mateus Farias Souza, Anderson Maciel Lima, Aleff Ferreira Francisco, Anderson Makoto Kayano, Maria Elisabeth Moreira de Lima Gusmão, Erika Crhistina Santos de Araújo, Guilherme Henrique Marchi Salvador, Marcos Roberto de Mattos Fontes, Juliana Pavan Zuliani, Andreimar Martins Soares

“…Methods: In silico assays were conducted to evaluate the interaction of crotapotin with LbTR using molecular docking and molecular dynamics techniques. …”
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[90Y]Y-L4-Lipo/ ethyl esters of Iodized fatty acids of poppy seed oil (lipiodol® ultra-fluid), a new TARE formulation, designed from a lipophilic ligand for stability and safety by Olivier Fougère, Anne Dencausse, Nicolas Lepareur, Gaetan Van Simaeys, Gilles Doumont, Isabelle Gardin, Elisabeth Renard, Claire Hollenbeck, Coraline De Maeseneire, Nicolas Passon, Olivier Rousseaux, Sarah Catoen

“…High activity stability in both in vitro and in vivo studies is needed to complete the formulation’s safety profile.…”
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Fluvio‐hydrological characteristics and diverse bedrock geology control the dynamic growth, truncation, and amalgamation of bedrock streambed and marine potholes by Biswajit Bera, Sumana Bhattacharjee, Uttam Mukhopadhyay, Debasis Sengupta, Pravat Kumar Shit, Nairita Sengupta, Supriya Ghosh, Arijit Ghosh, Soumik Saha, Sudipa Sarkar

“…Abstract A total of 393 potholes (368 fluvial and 25 marine potholes) were studied at seven different sites in both the fluvial and marine environments. …”
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Genome-wide identification, phylogenetic and expression pattern analysis of GATA gene family in Cerasus humilis by Meitong Pan, Chenzhuo Yue, Shan Jiang, Junbai Ma, Lengleng Ma, Lingyang Kong, Yang Ling, Wei Ma, Weichao Ren, Xiubo Liu

“…After the completion of the Cerasus humilis genome, investigations into its GATA gene family were not pursued.MethodsOur research team identified the GATA gene’s bioinformatics techniques, analyzed its structural characteristics and evolutionary trajectory, and investigated its expression patterns among various subfamilies.ResultsIn the C. humilis genome,20 ChGATAs are divided into four unique subgroups distributed over 7 chromosomes. …”
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Assessing the Antimicrobial Efficacy of Graphene Oxide and Its PEGylated Derivative Against <i>Staphylococcus aureus</i> by María F. Gilsanz-Muñoz, Mónica Martínez-Martínez, Javier Pérez-Piñeiro, Miriam Roldán, Mariana P. Arce, Rodrigo Blasco, Laura Rico-San Román, Fernando Esperón-Fajardo, Arisbel Cerpa-Naranjo, Bárbara Martín-Maldonado

“…After their production, both nanomaterials were characterized using various techniques to provide insight into their morphology, stability, and functional group composition. …”
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Microstructure evolution and fracture mechanism of Mo/Cu alloyed interface during plastic deformation by Bo Zhang, Yumeng Wang, Guoguang Li, Yunqi Lu, Wenlong Zhao, Xiaodi Wang, Yang Yang, Hong Xiao, Jinlong Du

“…In this study, molecular dynamics (MD) simulations were utilized to model the tensile and shear behaviors of the high-temperature and electric-field alloyed interface of the Mo/Cu system. …”
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Two natural products from the seeds of Citrus reticulata Blanco (Rutaceae) inhibit estrogen biosynthesis by regulating the PI3K-aromatase pathway by Xing Yang, Xi Chen, Chunqiao Shi, Qian Zhang, Qian Liu, Chunyan Zhou, Fawu Dong, Jinsong Su, Deming Liu, Yi Zhang

“…A comprehensive phytochemical analysis, employing various chromatographic techniques, led to the isolation of 26 compounds from SCR.ResultsThe effects of these compounds on estrogen biosynthesis were evaluated in human ovarian granulosa-like KGN cells, which play a crucial role in the progression of hormone-dependent breast cancers. …”
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Copper Methacrylate Complexes with Benzimidazole Derivatives: Structural Characterization and Antimicrobial Assays by Andra-Georgeta Andrei, Rodica Olar, Cătălin Maxim, Gina Vasile Scăețeanu, Ioana-Cristina Marinas, Madalina-Diana Gaboreanu, Mihaela Badea

“…In order to design antimicrobial species, a series of methacrylate (Macr) complexes, [Cu(HBzIm)₂(Macr)₂] (<b>1</b>), [Cu₂(HBzIm)₂(Macr)₄] (<b>2</b>), [Cu(2-MeBzIm)₂(Macr)₂] (<b>3</b>), [Cu₂(2-MeBzIm)₂(Macr)₄] (<b>4</b>), and [Cu(5,6-Me₂BzIm)₂(Macr)₂] (<b>5</b>) (HBzIm = benzimidazole, 2-MeBzIm = 2-methylbenzimidazole, and 5,6-Me₂BzIm = 5,6-dimethylbenzimidazole) were synthesized and characterized by several spectral techniques, as well as by single crystal X-ray diffraction. …”
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Electrophoretic deposition of monticellite nanoparticles on Ti implants for bone replacements: Physicochemical characteristics and in vitro biological assessments by Mohammadmahdi Akbari Edgahi, Seyedeh Neda Hosseini, Mohammad Reza Daghigh Shirazi, Reza Gholami, Seyed Morteza Naghib

“…Optimal electrophoretic deposition conditions were achieved by dispersing nanoparticles in ethanol at different acidic pH levels. …”
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Caracterización de bentonitas y zeolitas sin tratamiento como refuerzo en materiales compuestos de matriz polimérica//Characterization of untreated zeolites and bentonites as reinf... by Francisco Jesús Mondelo‐García, Liaqat Alí‐Shah, Francisco Jesús‐Almeida, José Luis Valín‐Rivera, María Grasa da-Silva‐Valenzuela, Francisco Rolando Valenzuela‐Díaz, Yosvani Guerra‐Silva, Frank Pérez‐Rodríguez

“…These materials were evaluated for physical and chemical assay techniques such as X-ray fluorescence, X-ray diffraction, scanning electron microscopy, moisture, cation exchange capacity, absorption and swelling aqueous<br />diluent. …”
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Evaluation of different sedation scales in the ICU management of COVID-19 patients by Sarah F. Al-Taie, Muzdalifa Mejbel Fedwi, Mohammed Merza, Mohammad Y. Alshahrani, M. M. Rekha, Mayank Kundlas, J. Bethanney Janney, Samir Sahoo, Hayder Ridha-Salman, Mohsen Khosravi

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CRISPR‐Based Environmental Biosurveillance Assisted via Artificial Intelligence Design of Guide‐RNAs by Benjamín Durán‐Vinet, Jo‐Ann L. Stanton, Gert‐Jan Jeunen, Ulla vonAmmon, Jackson Treece, Xavier Pochon, Anastasija Zaiko, Neil J. Gemmell

“…ABSTRACT Environmental biosecurity challenges are intensifying as climate change and human activities accelerate the spread of invasive species, disrupting ecosystem composition, function, and essential services. …”
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Development and Validation of In Vitro Assessment Protocol of Novel Intravenous Nanoemulsions for Parenteral Nutrition by Joanna Czerniel, Aleksandra Gostyńska-Stawna, Karina Sommerfeld-Klatta, Tomasz Przybylski, Violetta Krajka-Kuźniak, Maciej Stawny

“…<b>Methods:</b> Four NEs were formulated based on fatty acid profile analysis, and to demonstrate the applicability of our protocol, each NE utilized a distinct emulsifier system. …”
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A Deep Learning Framework for Healthy Lifestyle Monitoring and Outdoor Localization by Mehrab Rafiq, Naif S. Alshammari, Haifa F. Alhasson, Dina Abdulaziz Alhammadi, Mohammed Alshehri, Ahmad Jalal, Hui Liu

“…These results highlight the effectiveness of the preprocessing pipeline and feature optimization techniques in enhancing recognition and localization performance. …”
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Evaluation of the digital medicine perception by the youth consumer segment by Anna B. Tsvetkova, Anatoliy V. Shishkin

“…Young people, as a rule, more actively perceive any novelties and include еthem in their daily life. …”
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Antiviral and anti-inflammatory efficacy of nanoencapsulated brazilian green propolis against SARS-CoV-2 by Iasmin Rosanne Silva Ferreira, Isabela Araújo Justino, Ronaldo Bragança Martins, Maria Vitória Oliveira Souza, Thais Melquiades de Lima, Ana Maria de Freitas Pinheiro, Eurico Arruda, Jairo Kenupp Bastos, Priscyla Daniely Marcato

“…Brazilian green propolis extract was encapsulated in a microemulsion (ME-GP) and characterized using various physicochemical techniques. Furthermore, the antiviral and anti-inflammatory activities of ME-GP was evaluated in vitro and ex-vivo against SARS-CoV-2. …”
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