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Dual-Mode Treatment of Hepatocellular Carcinoma Using RGD Cyclopeptide-Modified Liposomes Loaded with Ce6/DOX
Published 2025-03-01“…Therefore, an effective drug delivery system must enhance drug accumulation at the target site, enable selective drug release there, and facilitate escape from lysosomes.Methods: cRGD-Lipo@Ce6/DOX was prepared by modifying c(RGDyK) onto the surface of drug-loaded liposomes containing Chlorin e6 (Ce6) and doxorubicin (DOX) through an amide reaction. …”
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Vancomycin-Loaded Isogenous Membrane Vesicles for Macrophage Activation and Intracellular Methicillin-Resistant Staphylococcus aureus Elimination
Published 2025-06-01“…Conventional antibiotics exhibit limited efficacy against intracellular MRSA due to poor cellular penetration.Methods: Vancomycin (VAN) was encapsulated into membrane vesicles (ΔagrAMVs) derived from the attenuated S. aureus strain RN4220ΔagrA, generating VAN-loaded nanoparticles (ΔagrAMV-VAN). In vitro and in vivo experiments were performed to test the efficacy of ΔagrAMV-VAN in intracellular MRSA clearance.Results: ΔagrAMV-VAN demonstrated sustained VAN release and efficient extracellular MRSA eradication. …”
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Mechanical properties and piecewise constitutive model of fine sandstone in mining area of western China
Published 2025-01-01Get full text
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Longitudinal shear behavior of composite slabs with recycled coarse and fine aggregate concrete
Published 2025-07-01Get full text
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Modulation Bandwidth Enhancement in Distributed Reflector Laser Based on Identical Active Layer Approach
Published 2018-01-01Get full text
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Neutrophils loaded NAD+ impede TLR4/NF-κB/NLRP3 pathway for sepsis treatment
Published 2025-10-01Get full text
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