An Innovative Management in the Diagnosis of Mediastinal Masses by G. Messina, D. G. Pica, G. Vicario, N. M. Giorgiano, R. Mirra, V. Di Filippo, F. Capasso, F. Panini D’Alba, R. Vinciguerra, B. Leonardi, M. A. Puca, M. Grande, M. Marvulli, M. Messinó, M. Ciaravola, L. Ferrante, G. Vicidomini, A. Fiorelli

“…Conclusion IUS‐guided biopsy allows for correct, safe, and precise identification of mediastinal lesions, establishing IUS as the “Gold Standard” for procedure guidance when the target lesion is adequately visualized.…”
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Prevalence, satisfaction and preference of tooth shades and their correlation with age, gender and skin shade: A cross sectional study [version 2; peer review: 1 approved, 2 approv... by Vignesh Kamath, Ann Sales, Sandipan Mukherjee, Puneeth Hegde, Sharon Saldanha, Mahesh M, Umesh Pai, Shobha Rodrigues, Thilak Shetty, Alisha Ono, Srikant Natarajan, Tanay Chawda, Prashanth Bajantri

“…Methods A total of 120 participants, 60 males and 60 females, categorized into four age (n=15): groups 20-30, 30-40, 40-50, & 50-60 yrs were recruited randomly and evaluated visually using the VITA 3D Master in the study. …”
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Preoperative clinical model to predict myocardial injury after non-cardiac surgery: a retrospective analysis from the MANAGE cohort in a Spanish hospital by Victoria Gomez, Ekaterine Popova, Javier Zamora, María Gómez-Rojo, David Pestaña, Gerard Urrútia, José Manuel del Rey, Ana Belen Serrano, Eva Ureta, Monica Nuñez, Borja Fernández Félix, Elisa Velasco, Javier Burgos, Alfonso Sanjuanbenito, Juan Manuel Monteagudo, Basilio de la Torre, Ángel Candela-Toha

“…We used Least Absolute Shrinkage and Selection Operator method to choose the factors included in the predictive model with MINS as dependent variable. …”
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A rapid and portable dual-mode RAA-CRISPR/Cas12a system for one-pot detection of spring viraemia of carp virus (SVCV) by Tian Hu, Zewei Hou, Yichen Zhao, Ye Zhang, Yufeng Si, Liqun Lu, Hao Wang

“…The fluorescence-based method exploits trans-cleavage activity of Cas12a to generate detectable fluorescent signals, while the LFD assay employs a FAM-biotin dual-labeled ssDNA probe for visual detection via colloidal gold accumulation on lateral flow strips. …”
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The impact of opioid analgesics with concomitant antipsychotic use on pain modulation and management in internal medicine: a cross-sequential study protocol by Nicola Grignoli, Nicola Grignoli, Nicola Grignoli, Simone Livoti, Simone Livoti, Angela Greco, Angela Greco, Michela Pironi, Roberta Noseda, Alessandro Ceschi, Alessandro Ceschi, Alessandro Ceschi, Alessandro Ceschi, Maria Luisa Garo, Luca Gabutti, Luca Gabutti

“…All patients with documented pain intensity assessment through a Visual Analogue Scale (VAS ≥ 1) will be included. …”
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Rethinking timing residuals: advancing PET detectors with explicit TOF corrections by Stephan Naunheim, Stephan Naunheim, Luis Lopes de Paiva, Luis Lopes de Paiva, Vanessa Nadig, Yannick Kuhl, Yannick Kuhl, Stefan Gundacker, Stefan Gundacker, Florian Mueller, Volkmar Schulz, Volkmar Schulz, Volkmar Schulz, Volkmar Schulz

“…PET is a functional imaging method that can visualize metabolic processes and relies on the coincidence detection of emitted annihilation quanta. …”
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DINOV2-FCS: a model for fruit leaf disease classification and severity prediction by Chunhui Bai, Chunhui Bai, Chunhui Bai, Lilian Zhang, Lilian Zhang, Lilian Zhang, Lutao Gao, Lutao Gao, Lutao Gao, Lin Peng, Lin Peng, Lin Peng, Peishan Li, Peishan Li, Peishan Li, Linnan Yang, Linnan Yang, Linnan Yang

“…However, the current prediction of disease degree by machine learning methods still faces challenges, including suboptimal accuracy and limited generalizability.MethodsIn light of the growing application of large model technology across a range of fields, this study draws upon the DINOV2 visual large vision model backbone network to construct the DINOV2-Fruit Leaf Classification and Segmentation Model (DINOV2-FCS), a model designed for the classification and severity prediction of diverse fruit leaf diseases. …”
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Effectiveness and Safety of Pharmacopuncture Therapy Compared to Standard Physical Therapy in Patients with Chronic Knee Pain: A Pilot Study for a Pragmatic Randomized Controlled T... by Myung In Jeong, Jun Kyu Lim, Yong Jun Kim, Yu Sun Jeon, Suna Kim, Chang Youn Kim, Yeon-Cheol Park, Eun-Jung Kim, Yejin Hong, Dongwoo Nam, Yoon Jae Lee, Doori Kim, In-Hyuk Ha

“…The type of PT solution or PT method was not determined in advance, leaving it to the clinician’s judgment. …”
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Retained Intrauterine Device (IUD): Triple Case Report and Review of the Literature by Mon-Lai Cheung, Shadi Rezai, Janelle M. Jackman, Neil D. Patel, Basem Z. Bernaba, Omid Hakimian, Dilfuza Nuritdinova, Catherine L. Turley, Ray Mercado, Takeko Takeshige, Sudha M. Reddy, Paul N. Fuller, Cassandra E. Henderson

“…Throughout the world, intrauterine contraceptive devices (IUDs) are a frequently used, reversible, popular contraceptive method. They are usually placed without major complications. …”
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Machine learning for epithelial ovarian cancer platinum resistance recurrence identification using routine clinical data by Li-Rong Yang, Mei Yang, Liu-Lin Chen, Yong-Lin Shen, Yuan He, Zong-Ting Meng, Wan-Qi Wang, Feng Li, Zhi-Jin Liu, Lin-Hui Li, Yu-Feng Wang, Xin-Lei Luo

“…We used laboratory and clinical data to create models based on machine learning for EOC platinum resistance recurrence identification.MethodsThis study was designed as a retrospective cohort analysis. …”
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Construction and validation of a prediction model for developing type 2 diabetes mellitus in patients with chronic obstructive pulmonary disease by Xi Kang, Tianye Li, Qinyang Chen, Hao Xu, Yanqiu Jiang, Hongjun Zhao, Xuhong Chang

“…Therefore, the purpose of this study was to identify the influencing factors of COPD complicated by T2DM and to construct a visualized disease prediction model.MethodWe included the medical records of 1,773 patients with COPD treated at Quzhou People’s Hospital from 2020 to 2023. …”
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KONSEP PERANCANGAN TAMAN RAMAH DIFABEL PADA TEPIAN SUNGAI MAHAKAM SAMARINDA KALIMANTAN TIMUR by Nur Husniah Thamrin, Hatta Musthafa AP

“…Edukasi akan disampaikan secara visual melalui bentukan-bentukan bangunan pada taman berupa bangunan dengan konsep Neo Vernakular khas Kalimantan Timur, ragam ornamen yang didesain pada pola lantai, ramp, dan bentuk taman labirin. …”
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Rationale and design of a comparison of angiography-derived fractional flow reserve-guided and intravascular ultrasound-guided intervention strategy for clinical outcomes in patien... by Qiang Liu, Shiqiang Li, Jinlong Zhang, Fan Jiang, Bin Yang, Jianan Wang, Jun Pu, Jun Jiang, Hao Zhou, Peng Chen, Liang Lu, Dongsheng Lu, Bon-Kwon Koo, Jinyu Huang, Lijun Guo, Xinyang Hu, Eun-Seok Shin, Shengxian Tu, Xiaoping Peng, Yibin Pan, Wenming He, Jilin Li, Zhenfeng Cheng, Jianliang Ma, Daqing Song, Yongzhen Fan, Zhaohui Meng, Lijiang Tang

“…However, whether this finding can be applied to angiography-derived FFR in significant coronary artery disease (CAD) remains unclear.Method and analysis The comparison of angiography-derived FFR-guided and IVUS-guided intervention strategies for clinical outcomes in patients with coronary artery disease (FLAVOUR II) trial is a multicentre, prospective, randomised controlled trial. …”
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Development and validation of a multimodal automatic interictal epileptiform discharge detection model: a prospective multi-center study by Nan Lin, Lian Li, Weifang Gao, Peng Hu, Gonglin Yuan, Heyang Sun, Fang Qi, Lin Wang, Shengsong Wang, Zi Liang, Haibo He, Yisu Dong, Zaifen Gao, Xiaoqiu Shao, Liying Cui, Qiang Lu

“…Abstract Background Visual identification of interictal epileptiform discharge (IED) is expert-biased and time-consuming. …”
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Children’s Headache Through Drawings: A Narrative Review and a Portrait Gallery by Floriana Ferro, Caterina Gaspari, Giulia Manfrè, Federica Cernigliaro, Daniela D’Agnano, Ruben Panzica, Edvige Correnti, Maria Rosita Ruta, Francesca Marchese, Renata Pitino, Mariarita Capizzi, Giuseppe Santangelo, Antonella Versace, Vittorio Sciruicchio, Vincenzo Raieli

“…Our goal is to create a visual reference that can aid clinicians in the accurate interpretation of children’s drawings. …”
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Assessing the psychometric properties of generic (EQ-5D-5L) and disease-specific (KCCQ) quality of life in patients with hypertrophic cardiomyopathy in the AFFECT-HCM study by Alexander Hirsch, Mickael Hiligsmann, Peter-paul Zwetsloot, Michelle Michels, Christian Knackstedt, Tjeerd Germans, Isabell Wiethoff, Stephan A.C. Schoonvelde, Rudolf A. de Boer, Silvia M.A.A. Evers, Wouter P. te Rijdt, Marjon A. van Slegtenhorst, Arend F.L. Schinkel

“…Background To assess the psychometric properties (content validity, reliability and construct validity) of generic and disease-specific health-related quality of life (HRQoL) instruments in patients with hypertrophic cardiomyopathy (HCM) and genotype-positive, phenotype-negative (G+/P−) individuals.Methods As part of the multicentre, observational AFFECT-HCM study, HRQoL was measured using the generic EuroQoL-5 Dimension-5 Level (EQ-5D-5L) questionnaire, the Visual Analogue Scale (EQ VAS) and the disease-specific Kansas City Cardiomyopathy Questionnaire (KCCQ). …”
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Acute Lateral Ankle Sprain Impairs Function and Strength Without Altering Muscle or Tendon Stiffness: A Controlled Observational Study by Pedro Bainy Franz, José Roberto deSouza Júnior, Hortência Cordeiro deLima, Estevão deSouza Diniz, Rogério deBrito Aguiar, Jeam Marcel Geremia, Henrique Mansur, Rita deCássia Marqueti, João Luiz Quagliotti Durigan

“…Ankle function, pain, and edema were evaluated using the Foot and Ankle Outcome Score, Visual Analog Scale, and figure‐of‐eight method. Plantar flexion strength was measured via isometric dynamometry. …”
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Rapid and sensitive detection of Mycobacterium tuberculosis using the RPA/Cas12f1_ge4.1 system with fluorescence and lateral flow readouts by Zhongliang Deng, Xingyong Weng, Honghua Tang, Tintao Zou, Xuan Zhou, Hangxi Liu, Piaoting Wen, Gemiao Luo, Tian Gan, Jun He

“…ABSTRACT Tuberculosis remains a major global health threat, with existing detection methods often limited by efficiency and resource demands. …”
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Heel kicking exercise rapidly improves pain and function in patients with acute lateral ankle sprain: a randomized controlled trial by Qi-Ning Qin, Xin Zhang, Ying-Feng Cai, Tian-Zhao Tian, Jian-Peng Zhou, Lin Li, Min Shi, Peng Huang, Hao-dong Liang, Jia-Hui Li, Zhan-Liang Tan, Yi-Xuan Fang, Jia-Wen Wang, Fang Zheng, Bao-Xin Liu

“…In this study, we designed an exercise—heel kicking exercise (HKE) based on the principles and methods of BST. This study aims to observe its true efficacy and safety. …”
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Technology-Enhanced Differentiated Instruction: A Narrative Review by Ata Barzegari, Esmaeil Azimi Yancheshmeh, Javad Hatami

“…Inclusion criteria focused on research that addressed DI at various educational levels and in different contexts, particularly those that investigated the use of TEL.Thematic analysis was used as the primary method of data analysis to identify recurring challenges faced by educators when implementing DI in online learning environments. …”
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