Exploring the efficacy and safety of Yu-Ping-Feng powder with variation against allergic rhinitis: a randomized, double-blind, placebo-controlled trial by Zhi-Xiu Lin, Tin Muk Ho, Yan-Fang Xian, Kam Leung Chan, Qing-Qing Xu, Cho Wing Lo, Justin Che Yuen Wu, Kam Lun Hon, Sin Bond Leung, Chon Pin Chia, Chi Him Sum, Tak Yee Chow, Pui Kuan Cheong, Jessica Yuet Ling Ching, Hongwei Zhang, Ka Chun Leung, Wai Ling Lin

“…Purpose To evaluate the efficacy and safety of YPV on AR patients with the lung and spleen Qi deficiency type using a randomized, double-blind, placebo-controlled clinical trial (RCT). Study design and methods Between April 2022 and June 2023, a total of 58 participants were recruited and randomly allocated to receive either YPV (n = 29) or placebo (n = 29) for 8 consecutive weeks. …”
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Elevated thiamine level is associated with activating interaction between HIF-1α and SLC19A3 in experimental myopic guinea pigs by Zhongyu Ma, Jiawen Hao, Zhaohui Yang, Miao Zhang, Ruixue Zhang, Jizhao Xin, Bo Bao, Xuewei Yin, Xuewei Yin, Hongsheng Bi, Hongsheng Bi, Hongsheng Bi, Dadong Guo, Dadong Guo, Dadong Guo, Dadong Guo

“…This study aimed to investigate the process of thiamine changes in choroidal tissue of guinea pigs with negative lens-induced myopia (LIM).MethodsThe right eyes of guinea pigs in the LIM group wore −6.0D lenses to model experimental myopia. …”
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Investigating the molecular mechanisms and clinical potential of APO+ endothelial cells associated with PANoptosis in the tumor microenvironment of hepatocellular carcinoma using s... by Zhaorui Cheng, Xiangyu Yang, Yi Ren, Huimin Wang, Qi Zhang, Sailing Lin, Wenhao Wu, Xiaolu Yang, Jiahan Zheng, Xinzhu Liu, Xin Tao, Xiaoyong Chen, Yuxin Qian, Xiushen Li

“…This study aims to investigate these mechanisms using single-cell RNA sequencing data. Methods: Single-cell RNA sequencing data from HCC patients were obtained from the GEO database. …”
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Maintenance of patient-reported health-related quality of life post neoadjuvant relugolix prior to the initiation of prostate radiation therapy by Min Jung Koh, Min Ji Koh, Jessica Y. Hsueh, Lindsey Gallagher, Malika Danner, Alan Zwart, Marilyn Ayoob, Deepak Kumar, Michael Carrasquilla, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…The main objective of this prospective study was to explore the effects of neoadjuvant relugolix on health-related quality of life in prostate cancer patients immediately prior to stereotactic body radiation therapy (SBRT).MethodsPatients treated at Georgetown between January 2021 and September 2023 with neoadjuvant relugolix per an institutional protocol were included in the study (IRB 12-1775). …”
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Comparison of Deep Learning and Clinician Performance for Detecting Referable Glaucoma from Fundus Photographs in a Safety Net Population by Van Nguyen, MD, Sreenidhi Iyengar, Haroon Rasheed, MD, Galo Apolo, Zhiwei Li, Aniket Kumar, Hong Nguyen, Austin Bohner, MD, Kyle Bolo, MD, Rahul Dhodapkar, MD, Jiun Do, MD, PhD, Andrew T. Duong, MD, Jeffrey Gluckstein, MD, Kendra Hong, MD, Lucas L. Humayun, Alanna James, MD, Junhui Lee, MD, Kent Nguyen, OD, Brandon J. Wong, MD, Jose-Luis Ambite, PhD, Carl Kesselman, PhD, Lauren P. Daskivich, MD, Michael Pazzani, PhD, Benjamin Y. Xu, MD, PhD

“…A DL algorithm based on the Visual Geometry Group-19 architecture was trained using patient-level labels generalized to images from both eyes. …”
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Exploring the role of hyperreflective walls as a biomarker for the management of cystoid macular edema by Zhang-Rong Yang, Chang Li, Dong-Jun Xing, Gao-Xu Wei, Ce-Ce Zhao, Miao Zhou, Xiao-Han Ma, Yi Zhao, Shu Yang, Rong-Guo Yu, Zhi-Qing Li

“…AIM: To investigate the prevalence and clinical implications of hyperreflective walls (HRW) in foveal cystoid spaces in patients with cystoid macular edema (CME) caused by retinal diseases and noninfectious uveitis (NIU). METHODS: This retrospective cross-sectional study included 443 eyes with CME secondary to diabetic macular edema (DME), retinal vein occlusion (RVO), retinitis pigmentosa (RP), neovascular age-related macular degeneration (nAMD), and NIU. …”
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Thymic characteristics in patients with autoimmune diseases: a multicentre radiological observational studyResearch in context by Haoxiao Chang, Junqiang Yan, Anxin Wang, Ningning Wang, Peng Liu, Yemin Shi, Xin Zhao, Jinqiao Zhu, Yuan Cai, Xue Xia, Yunyi Hao, Shiyi Yin, Jing Wang, Xinli Wang, Lina Sun, Jia Ma, Xiaoyu Huang, Haonan Guan, De-Cai Tian, Kaibin Shi, Ganqin Du, Wenhao Huang, Guoyan Qi, Hao Li, Yongjun Wang, Fu-Dong Shi, Zhang Zhang, Wei-Na Jin

“…Thymic fatty replacement was evaluated using a four-point visual scoring scale (0–3). This study is registered with the Chinese Clinical Trial Registry (ChiCTR2300078417). …”
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Combined [18F]Fluorodeoxyglucose PET and [123I]Iodometomidate-SPECT for diagnostic evaluation of indeterminate adrenal neoplasias—the cross-sectional diagnostic test accuracy study... by Stefanie Hahner, Philipp Hartrampf, Felix Beuschlein, Matthias Miederer, Konstanze Miehle, Wiebke Schlötelburg, Carmina Teresa Fuß, Thomas Pfluger, Christian Fottner, Anke Tönjes, Ken Herrmann, Holger Amthauer, Martin Reincke, Mathias Schreckenberger, Osama Sabri, Johanna Werner, Miriam Reuter, Stefan Kircher, Wiebke Arlt, Martin Fassnacht, Andreas Konrad Buck, Hans-Helge Müller, Andreas Schirbel, Christian Furth, Knut Mai, Marcus Quinkler, Frank Weber, Henning Dralle, Benjamin Sandner, Thomas Lincke, Regine Kluge, Nada Rayes, Matthias Weber, Martina Gräsl, Wolfgang Saeger, Joachim Reibetanz

“…We proposed that combined molecular imaging with [18F]Fluorodeoxyglucose-positron emission tomography (FDG PET) and [123I]Iodometomidate-single photon emission tomography (IMTO SPECT) improves non-invasive classification of ACA. Methods: This cross-sectional, multicentre diagnostic study included patients (≥30 years) with non-functioning indeterminate adrenal masses (>3 cm or increase >1 cm, Hounsfield units [HU] ≥10 on unenhanced computed tomography [CT]) scheduled for surgery. …”
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An allelic atlas of immunoglobulin heavy chain variable regions reveals antibody binding epitope preference resilient to SARS-CoV-2 mutation escape by Weiqi Deng, Weiqi Deng, Xuefeng Niu, Ping He, Ping He, Qihong Yan, Qihong Yan, Huan Liang, Yongping Wang, Yongping Wang, Lishan Ning, Lishan Ning, Zihan Lin, Zihan Lin, Yudi Zhang, Xinwei Zhao, Xinwei Zhao, Liqiang Feng, Linbing Qu, Ling Chen, Ling Chen

“…BackgroundAlthough immunoglobulin (Ig) alleles play a pivotal role in the antibody response to pathogens, research to understand their role in the humoral immune response is still limited.MethodsWe retrieved the germline sequences for the IGHV from the IMGT database to illustrate the amino acid polymorphism present within germline sequences of IGHV genes. …”
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Reconstruction of a lncRNA-Associated ceRNA Network in Endothelial Cells under Circumferential Stress by Zhuhui Huang, William Adiwignya Winata, Kui Zhang, Yang Zhao, Yang Li, Ning Zhou, Shaoyou Zhou, Wei Fu, Bokang Qiao, Guoqi Li, Yihui Shao, Jubing Zheng, Ran Dong

“…We constructed and visualized a lncRNA-miRNA-mRNA network, and the top 20 nodes are identified after calculating their degrees. …”
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Cost‐effectiveness of a multicomponent intervention against cognitive decline by Christian Brettschneider, Elżbieta Buczak‐Stec, Melanie Luppa, Andrea Zülke, Bernhard Michalowsky, Anika Rädke, Alexander Bauer, Christine Brütting, Robert P. Kosilek, Isabel Zöllinger, Juliane Döhring, Martin Williamson, Birgitt Wiese, Wolfgang Hoffmann, Thomas Frese, Jochen Gensichen, Hanna Kaduszkiewicz, Jochen René Thyrian, Steffi G. Riedel‐Heller, Hans‐Helmut König, the AGEWELL.DE study group

“…The aim of this multicenter cluster‐randomized controlled trial was to assess the cost‐effectiveness of a multi‐domain intervention to prevent cognitive decline in older people who are at risk for dementia. METHODS We used data from a multi‐centric, two‐armed, cluster‐randomized controlled trial (AgeWell.de trial, ID: DRKS00013555). …”
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Cost-effectiveness of angiographic quantitative flow ratio-guided coronary intervention: A multicenter, randomized, sham-controlled trial by Yanyan Zhao, Changdong Guan, Yang Wang, Zening Jin, Bo Yu, Guosheng Fu, Yundai Chen, Lijun Guo, Xinkai Qu, Yaojun Zhang, Kefei Dou, Yongjian Wu, Weixian Yang, Shengxian Tu, Javier Escaned, William F. Fearon, Shubin Qiao, David J. Cohen, Harlan M. Krumholz, Bo Xu, Lei Song, On behalf of FAVOR III China Study Group, Ting Gao

“…This study aimed to assess the cost-effectiveness of QFR-guided PCI from the perspective of the current Chinese healthcare system. Methods:. This study is a pre-specified analysis of the FAVOR III China trial, which included 3825 patients randomized between December 25, 2018, and January 19, 2020, from 26 centers in China. …”
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Inspiring Social Capital Through Community Green Space: Pathways and Implications by Lin YE, Shi HE, Yinghao LI, Zhaohui YAN, Lei HUANG

“…Under China’s precision governance paradigm emphasizing data-driven policymaking, this research systematically investigates the operational mechanisms through which community green spaces inspire social capital, incorporating both grassroots practices and institutional innovations, based on which evidence-based optimization strategies for urban renewal practices are proposed.MethodsThis research combines visual mapping analysis based on CitieSpace software with a number of inductive and deductive review methods. …”
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Effects of radiofrequency electromagnetic field exposure on cancer in laboratory animal studies, a systematic review by Meike Mevissen, Angélique Ducray, Jerrold M. Ward, Annette Kopp-Schneider, James P. McNamee, Andrew W. Wood, Tania M. Rivero, Kurt Straif

“…Objective: The objective of this review was to systematically evaluate the effects of RF EMF exposure on cancer in experimental animals. Methods: Eligibility criteria: Based on pre-established Populations, Exposures, Comparators, Outcomes, and Study Type (PECOS) criteria, studies in experimental animals of the following study types were included: chronic cancer bioassays, initiation-(co–)promotion studies, and studies with tumor-prone animals.Information sources: MEDLINE (PubMed), Science Citation Index Expanded and Emerging Sources Citation Index (Web of Science), and the EMF Portal.Data abstraction and synthesis: Data are publicly available online as interactive visuals with downloadable metadata. …”
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Diabetic Retinopathy Assessment through Multitask Learning Approach on Heterogeneous Fundus Image Datasets by Hongkang Wu, MS, Kai Jin, MD, PhD, Yiyang Jing, MD, Wenyue Shen, MD, Yih Chung Tham, PhD, Xiangji Pan, PhD, Victor Koh, MD, PhD, Andrzej Grzybowski, MD, PhD, Juan Ye, MD, PhD

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Toripalimab plus axitinib in patients with metastatic mucosal melanoma: 3-year survival update and biomarker analysis by Xuan Wang, Jie Dai, Li Zhou, Hui Feng, Jun Guo, Xue Bai, Lu Si, Bixia Tang, Chuanliang Cui, Xinan Sheng, Siming Li, Zhihong Chi, Lili Mao, Bin Lian, Xieqiao Yan, Yan Kong, Xiaowen Wu, Xiongwen Tang, Keith T Flaherty

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Nano-based perivascular intervention sustains a nine-month long-term suppression of intimal hyperplasia in vein grafts by Takuro Shirasu, Go Urabe, Nisakorn Yodsanit, Yitao Huang, Ruosen Xie, Matthew S. Stratton, Matthew Joseph, Zhanpeng Zhang, Yuyuan Wang, Jing Li, Runze Tang, Lynn M. Marcho, Li Yin, Eric W. Kent, Kaijie Zhang, Ki Ho Park, Bowen Wang, K. Craig Kent, Shaoqin Gong, Lian-Wang Guo

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Zonation of Debris Cones and Talus Slopes in Aghlaghan Chay Basin (South Western Slope of Sabalan Mountain) by aghil Madadi, ata gafari, elnaz piroozi

“…The purpose of this study is Assessment and zonation Debris cones and Talus slopes. 2- Materials and Methods In this research, two methods of library and field study have been utilized to gather data and information. …”
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A CECT-Based Radiomics Nomogram Predicts the Overall Survival of Patients with Hepatocellular Carcinoma After Surgical Resection by Peng Zhang, Yue Shi, Maoting Zhou, Qi Mao, Yunyun Tao, Lin Yang, Xiaoming Zhang

“…The optimal performance model was further visualized as a nomogram, and its predictive accuracy was evaluated via calibration curves and decision curve analysis (DCA). …”
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Risk factors for methotrexate treatment failure in tubal ectopic pregnancy: a retrospective cohort study by Linru Fu, Xinyan Liu, Zhao Tian, Zhe Du, Xinyi Wang, Xiuqi Wang, Xiaodong Li, Tao Xu, Zhijing Sun

“…A nomogram was developed to visualize the predictive factors. Results A total of 359 patients were included, with 268 (74.7%) succeeding with MTX and 91 (25.3%) required surgery. …”
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