The first experience of using upadacitinib in the treatment of rheumatoid arthritis in real clinical practice (results of the multicenter project “RACURS”) by V. N. Amirjanova, A. E. Karateev, E. Y. Pogozheva, A. A. Baranov, V. I. Mazurov, R. R. Samigullina, O. N. Anoshenkova, N. A. Lapkina, T. Yu. Grineva, E. L. Nasonov, A. M. Lila

“…During the first week of taking the drug, there was a marked decrease in pain from 60 to 30 mm on a visual analogue scale, which lasted until the third month of therapy. …”
Get full text

Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates by Jian Zhang, Youlin Zhu, Ping Yuan, Xiaojuan Dong, Manyun Xie, Zongrui Ma, Rong Tian

Get full text

Age-related features of calcium pyrophosphate deposition disease by M. S. Eliseev, O. V. Zhelyabina, M. N. Chikina

“…The age-related features of the disease have not been studied.Objective: to study age-related features of CPPD.Subjects and methods. A total of 113 patients (54 men and 59 women) who had received inpatient or outpatient treatment at the V.A. …”
Get full text

Comparison of the effects of IMRT and IMPT on MRI features of normal brain tissue: a retrospective study by Jian Xu, Lili Zhang, Tingting Liu, Qingzeng Liu, Jian Zhu

“…And evaluate the potential application value of radiomic features in dose optimization and biological dose assessment. Methods A retrospective analysis included 113 patients undergoing brain-target radiotherapy: 44 receiving IMPT (average total dose: 5713.63 ± 774.32 cGy) and 69 receiving IMRT (average total dose: 5489.86 ± 627.05 cGy). …”
Get full text

The i‐gel® supraglottic airway device compared to endotracheal intubation as the initial prehospital advanced airway device: A natural experiment during the COVID‐19 pandemic by Daniel B. Levi, Joris Hoogendoorn, Shenae Samuels, Lindsay Maguire, Ruben Troncoso, Scott Gunn, Matthew Katz, Christine VanDillen, Susan A. Miller, Jay L. Falk, Steven H. Katz, Linda Papa

“…The objective was to compare first‐pass success and timing to successful airway placement between ETI and the i‐gel® SGA under extenuating circumstances. Methods This pre/post study compared airway placement metrics in prehospital patients requiring advance airway management for non‐trauma‐related conditions. …”
Get full text

Triple positivity for autoantibodies in patients with rheumatoid arthritis is associated with a severe course of the disease but not with bone turnover markers by Tomasz Budlewski, Joanna Sarnik, Olga Brzezinska, Anna Lewandowska-Polak, Tomasz Poplawski, Joanna Samanta Makowska

“…This study aimed to evaluate the correlation between autoantibody profiles, disease activity, bone turnover markers, and selected SNPs in a cohort of Polish RA patients. Material and methods A total of 138 RA patients from the Department of Rheumatology, Medical University of Lodz, were enrolled. …”
Get full text

Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parall... by Kyoko Kikuno, Ryuta Asada, Takuma Ishihara, Yoshimasa Bomoto, Saki Murase, Yoko Ueda, Tomomi Shiga, Yoh Hayasaki, Tatsuro Furui, Satoko Matsuzaki, Masahiko Takemura, Kazutoshi Matsunami, Makoto Kubo, Naoki Ito, Masanori Isobe, Ken-ichirou Morishige

“…The primary endpoint is the change in the pain visual analog scale (VAS) score from baseline to 48 weeks. …”
Get full text

Patient-specific computational flow simulation reveals significant differences in paravisceral aortic hemodynamics between fenestrated and branched endovascular aneurysm repair by Kenneth Tran, MD, Celine Deslarzes-Dubuis, MD, Sebastien DeGlise, MD, Adrien Kaladji, MD, Weiguang Yang, PhD, Alison L. Marsden, PhD, Jason T. Lee, MD

“…CFS is a novel tool for quantifying and visualizing the unique patient-specific hemodynamic effect of different complex EVAR strategies. …”
Get full text

In vitro Study of Fungus-Like Organisms Peronospora ficariae and Wilsoniana bliti as Potential Inhalant Allergens by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…They negatively impact crop production, reduce the quality of agricultural goods, and lessen the visual appeal of decorative plants. Additionally, these fungi can pose a health hazard to humans, as they are significant sources of allergens. …”
Get full text

Expression characteristics of miR-502-5p/p53/NF-κB signaling pathway in patients with different degrees of knee osteoarthritis: a cross-sectional observational study with methodolo... by Xiaozhe Zhang, Kesong Shi, Anmin Ruan, Pu Chen, Tao Zhang, Qingpu Wang

“…Clinical assessments included Visual Analog Scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores. …”
Get full text

Acupuncture effects of post-stroke thalamic pain: a systematic review and meta-analysis of randomized controlled trials by Tianwei Zhang, Tianwei Zhang, Junying Zhai, Junying Zhai, Ling Cheng, Ling Cheng, Kaixin Jiang, Kaixin Jiang, Dayang Wang, Huawei Shi, Bin Wang, Xing Chen, Xinglu Dong, Li Zhou

“…Outcome measures included the total efficacy rate, visual analogue scale (VAS), present pain intensity score (PPI), pain rating index (PRI), β-endorphin (β-EP), substance P (SP) and adverse reactions. …”
Get full text

Capabilities of Dynamic Magnetic Resonance Angiography in Patients With Cerebral Aneurysms in the Postoperative Period by D. O. Kardailskaya, E. I. Zyablova, T. N. Trofimova, I. N. Sever, D. V. Litvinenko, V. V. Tkachev, V. A. Pоrhanov

“…Magnetic resonance angiography (MRA) has recently become increasingly attractive for the follow-up of surgically treated CAs because it is noninvasive, does not require hospitalization, and reduces complications associated with the frequent use of cerebral angiography.Objective: To evaluate capabilities of dynamic MRA in postoperative monitoring of patients with CAs.Materials and methods: The study was conducted at the premises of the Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1 (Krasnodar, Russian Federation). …”
Get full text

Problematic Social Media Use, Self-Objectification, and Body Image Disturbance: The Moderating Roles of Physical Activity and Diet Intensity by Çınaroğlu M, Yılmazer E

“…It also explores the psychological outcomes of depression and anxiety.Methods: A cross-sectional study was conducted with 594 women aged 18– 65 in Istanbul, Türkiye. …”
Get full text

Application of auricular acupoint scraping therapy in postoperative patients with lower extremity fracture (耳穴推刮术在下肢骨折术后患者中的应用) by GUI Huiqiong (桂辉琼), WANG Yihua (王一华), YUAN Qingna (袁庆娜), JI Chen (冀晨), YANG Yihua (杨毅华)

“…Objective To observe the effect of auricular acupoint scraping therapy on postoperative pain and sleep quality of patients with lower extremity fracture. Methods Totally 70 cases of patients undergoing surgery for lower limb fracture were randomly divided into control group and observation group, with 35 cases in each group. …”
Get full text

Effect of bagging on nutritional quality and mineral element content of peach fruit in different varieties by CHEN Meng, ZHANG Xue, LI Yue, LI Yong, CHEN Xiaolong, CHEN Jian, YU Xiangyang

“…The study aimed to evaluate the impact of bagging on the nutritional quality and mineral element content of peach fruit in various varieties. [Methods] Three peach varieties from Jiangsu including Baifeng, Xiacui, and Xiahui were tested. …”
Get full text

CD79A and GADD45A as novel immune-related biomarkers for respiratory syncytial virus severity in children: an integrated machine learning analysis and clinical validation by Juan Juan Chen, Zhang Ze Lu, Yu Xin Jing, Xing Mei Nong, Yi Qin, Jin Yang Huang, Na Lin, Jie Wei

“…Herein, we investigated the differential expression biomarkers between RSV infected hospitalized patients, healthy groups and RSV infected outpatients.MethodsTwo publicly available transcriptomic datasets (GSE77087 and GSE188427) were retrieved from the Gene Expression Omnibus (GEO) database. …”
Get full text

Kirjeldamisest lavastamiseni. Loovuurimuslik vaade / From Describing to Staging: A Practice-as-Research Look by Karl Saks, Hedi-Liis Toome, Anu Sööt, Ele Viskus

“…Being able to describe—therefore express verbally both auditory and visual elements present in the environment—is a very relevant skill for directors. …”
Get full text

Evaluation of the efficacy of high molecular weight hyaluronic acid with chondroitin sulfate in post-traumatic knee osteoarthritis by E. I. Bialik, M. A. Makarov, V. A. Nesterenko, V. E. Bialik, A. E. Karateev, A. A. Bialik, V. I. Stadnik

“…Objective: to evaluate the efficacy of a single or double administration of a preparation of high molecular weight hyaluronic acid (HLA) with chondroitin sulfate (CS) in post-traumatic knee osteoarthritis (OA). Material and methods. The study included 91 patients with stage III post-traumatic knee OA. …”
Get full text

Damage to the Cardiovascular System in Patients with SARS-CoV-2 Coronavirus Infection. Part 2: Correction of Myocardial Systolic Dysfunction by V. I. Podzolkov, A. I. Tarzimanova, A. E. Bragina, I. I. Shvedov, E. E. Bykova, A. A. Ivannikov, L. V. Vasilyeva

“…To study changes in myocardial contractile function when prescribing mineralocorticoid receptor antagonists of spironolactone in patients after coronavirus infection SARS-CoV-2 with symptoms of chronic heart failure (CHF).Materials and methods. The study included 90 hospitalized patients with a diagnosis of SARS-CoV-2 coronavirus infection. …”
Get full text

Overcoming challenges and achieving high HPV vaccination uptake in Cameroon: lessons learned from a gender-neutral and single-dose program and community engagement by Andreas Ateke Njoh, Dur-E-Nayab Waheed, Tchokfe Shalom Ndoula Josue Kedakse, Lionel Junior Ebongue, Eugene Justine Kongnyuy, Adidja Amani, Afizu Chrakoh Tambasho, Yauba Saidu, Mohamed II Kaba, Clovis Nchinjoh Sangwe, Herman Kenfack, Judith Seungue, Daniel Nebongo, Nadege Edwige Nnang, Alex Vorsters, Laurent Cleenewerck de Kiev

“…Microsoft Excel 365 was used for calculating vaccination coverage proportions and visualizing results through figures and tables. Results Cameroon introduced the HPV vaccine to nine-year-old girls in October 2020 amidst negative rumours. …”
Get full text