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  1. 21701

    Socio‐economic status and adherence to HIV preventive and therapeutic interventions: exploring the mediating role of food insecurity among men who have sex with men and transgender... by Paula M. Luz, Thiago S. Torres, Victor C. Matos, Giovanna G. Costa, Brenda Hoagland, Cristina Pimenta, Marcos Benedetti, Beatriz Grinsztejn, Valdilea G. Veloso

    Published 2025-03-01
    “…Self‐report of ART adherence was measured by the WebAd‐Q instrument (3‐items/past week) plus a visual analogue scale. Self‐report of PrEP adherence was measured by the number of days the person took PrEP in the past week. …”
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  2. 21702
  3. 21703

    Transitional and CD21− PD-1+ B cells are associated with remission in early rheumatoid arthritis by Sarah McGrath, Boel Sundbeck, Katrin Thorarinsdottir, Charlotte A. Jonsson, Alessandro Camponeschi, Monica Leu Agelii, Anna-Karin H. Ekwall, Merete Lund Hetland, Mikkel Østergaard, Till Uhlig, Michael Nurmohamed, Jon Lampa, Dan Nordström, Kim Hørslev-Petersen, Bjorn Gudbjornsson, Gerdur Gröndal, Ronald van Vollenhoven, Anna Rudin, Inga-Lill Mårtensson, Inger Gjertsson

    Published 2025-04-01
    “…In this study, we sought to identify B-cell subset(s) at diagnosis that might be associated with Clinical Disease Activity Index (CDAI) remission at 24-week follow-up. Methods Seventy early RA patients from the NORD-STAR trial, recruited from two Swedish sites, and 28 matched healthy controls, were included in this spin-off study. …”
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  4. 21704

    Exploration of the molecular mechanism of melatonin against polycystic ovary syndrome based on a network pharmacology approach and experimental validation by Ran Cheng, Ran Cheng, Ran Cheng, Ying Zhu, Sheng-kai Wang, Chun-Xiao Zong, Hong-Li Zhao, Hong-Li Zhao, Hong-Li Zhao, Qin Zhang, Qin Zhang, Qin Zhang

    Published 2025-08-01
    “…This study integrated network pharmacology, molecular docking, molecular dynamics simulations, and laboratory confirmation to explore the pharmacological mechanisms of melatonin in PCOS.MethodsFirst, we conducted animal studies to evaluate the therapeutic efficacy of melatonin by administering it to circadian disruption-induced PCOS-like rats. …”
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  5. 21705
  6. 21706

    Dietary antioxidants and flavonoids are inversely associated with prostate cancer risk and mortality: evidence from NHANES and machine learning by Yanyang Jin, Dong-shan Lv, Li-po Zhou, Li Xiao, Guang-quan Tong, Abdallah Karim, Shuai Xue, Hongyang Tian, Cheng-cai Wang, Kun Feng, Ding-ming Song, You-liang Guan

    Published 2025-07-01
    “…Shapley Additive Explanations (SHAP) values identified key predictors and visualized their effects.ResultsAmong 2,629 U.S. male participants from NHANES 2007–2010, 144 reported a history of PCa. …”
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  7. 21707
  8. 21708

    Early menopause is associated with higher disease activity independent of inflammation in postmenopausal-onset rheumatoid arthritis by Zhi-Ming Ouyang, Yao-Wei Zou, Ye Lu, Jie Pan, Tao Wu, Pei-Wen Jia, Hu-Wei Zheng, Yun Su, Le-Feng Chen, Jian-Zi Lin, Kui-Min Yang, Pei-Yu Lin, Jin-Yuan Han, Jian-Da Ma, Lie Dai

    Published 2025-03-01
    “…We aimed to investigate its impact on disease characteristics in RA patients. Methods This cross-sectional study included natural post-menopausal RA patients from an observational RA cohort recruited between January 2015 and October 2023. …”
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  9. 21709

    Deciphering the anticoccidial mechanism of Qinghao Changshan formula through network pharmacology and molecular docking by Dong Tian, Hui Fu, Hongxia Tao, Miaolan Li, Qinghua Zhang, Weidong Deng

    Published 2025-08-01
    “…Overlapping targets were visualized using Venn diagrams, and protein–protein interaction (PPI) networks were constructed using STRING and Cytoscape. …”
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  10. 21710

    Cervical Spine Pain and the Impact on the Quality of Life of Patients with Multiple Sclerosis by Martyna Odzimek, Hubert Lipiński, Małgorzata Błaszczyk, Patrycja Strózik, Julia Zegarek, Piotr Dubiński, Agata Michalska, Justyna Klusek, Marek Żak, Waldemar Brola

    Published 2024-11-01
    “…<i>Background and Objectives</i>: The main aim of this study was to evaluate the impact of cervical pain on the quality of life of patients with multiple sclerosis in comparison with a group of healthy people (without diseases of the Central Nervous System). <i>Materials and Methods</i>: Data were collected at the Specialist Hospital St. …”
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  11. 21711

    CLP-Net: an advanced artificial intelligence technique for localizing standard planes of cleft lip and palate by three-dimensional ultrasound in the first trimester by Guangzhi He, Zhou Li, Zhiyuan Zhu, Tong Han, Yan Cao, Chaoyu Chen, Yuhao Huang, Haoran Dou, Lianying Liang, Fangmei Zhang, Jin Peng, Tao Tan, Hongmei Liu, Xin Yang, Dong Ni

    Published 2025-01-01
    “…CLP-Net predictions had a highly visual acceptance rate among radiologists (MSP: 95%, RTP: 70%, MAP: 70%), with improved localization speed 15s(31.3%) for senior radiologists and 63s(38.9%) for junior radiologists. …”
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  12. 21712

    Integrating clinical trial landscapes and bibliometric analysis: unveiling the impact of PD-1/PD-L1 inhibitors on renal cell carcinoma research and therapeutic trajectories summary by Yuanbin Huang, Yuanbin Huang, Xinmiao Ma, Hengxing Zhu, Chen Shen, Ke Hu, Yang Yu, Aoyu Yang, Zhuo Liu, Chuanyang Liu, Wenrui Shi, Wei Wang, Xueyan Xia, Jiawen Wang, Xiancheng Li

    Published 2025-07-01
    “…Thus, we aim to assess the global scientific outcomes of studies focusing on PD-1/PD-L1 in RCC from 2005 to 2024 and to identify emerging research trends.MethodsData were collected from the Web of Science Core Collection using a predefined search strategy. …”
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  13. 21713

    Insights into De Quervain’s Tenosynovitis as an Unintended Consequence of Problematic Smartphone Usage: A Cross-sectional Observational Study by Aswin Sugumaran, Dilip Kumar Naidu, Madhan Raju, Sabari Vaasan Lakshmikanthan, S Karthikeyan, Kevin Dhas, Vamsi Krishna, Praveen Raja

    Published 2025-04-01
    “…Materials and Methods: A cross-sectional observational study was conducted at the Department of Orthopaedics, SRM Medical College Hospital and Research Centre, SRM Institute of Science and Technology, Chengalpattu, Tamil Nadu, India, from July 2024 to September 2024, with 300 participants aged 20-50 years. …”
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  14. 21714

    The Incorporation of CBD into Biodegradable DL-Lactide/Glycolide Copolymers Creates a Persistent Antibacterial Environment: An In Vitro Study on <i>Streptococcus mutans</i> and <i>... by Ronit Vogt Sionov, Ahmad Siag, Emma Theresa Mersini, Natalya M. Kogan, Tatiana Alkhazov, Igor Koman, Praveen Rowlo, Vitaly Gutkin, Menachem Gross, Doron Steinberg

    Published 2025-04-01
    “…Biofilm formation on the polymer scaffolds was visualized by HR-SEM. Its anti-inflammatory effect was determined by measuring the IL-6 release from LPS-stimulated RAW 264.7 macrophages by ELISA. …”
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  15. 21715
  16. 21716

    The value of home-centered dressing change model in wound healing after low simple anal fistulectomy—a cross-sectional study by Zhang Linhan, Jia Shize, Wei Kaikai, Wan Xingyang, Ren Donglin, Lin Hongcheng, Liu Zhimin

    Published 2024-06-01
    “…[Objectives] To investigate the value of home-centered dressing change model in wound healing after low simple anal fistulectomy. [Methods] Total of the sixty-four patients with low simple anal fistula who underwent fistulectomy at the Department of Anorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University from June 2022 to December 2022 were included as the study subjects. …”
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  17. 21717

    HORNBILL: A First-in-Human Phase I/IIa Study of the Safety, Tolerability, and Early Pharmacodynamics of BI 764524 for Diabetic Macular Ischemia by Quan Dong Nguyen, MD, MSc, Chirag Jhaveri, MD, Maged Habib, MD, Yasir J. Sepah, MBBS, Khaled Nassar, MD, PhD, Bartlomiej Krawczyk, PhD, Gudrun Simons, PhD, Andrea Giani, MD, Elizabeth Pearce, PhD, Martin Gliem, MD, Mohamed Ahmed, MBBCh, MD, Sobha Sivaprasad, DM

    Published 2025-09-01
    “…Participants: Adults with DMI and stable diabetic retinopathy (DR) treated with pan-retinal photocoagulation and without center-involving diabetic macular edema. Methods: Twelve participants received single IVT doses of BI 764524 0.5 mg (n = 3), 1.0 mg (n = 3), or 2.5 mg (n = 6) in the SRD part. …”
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  18. 21718

    Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid... by Yaoyao Xu, Qiaoyan Cai, Chunyu Zhao, Weixiang Zhang, Xinting Xu, Haowei Lin, Yuxing Lin, Daxin Chen, Shan Lin, Peizhi Jia, Meiling Wang, Ling Zhang, Wei Lin

    Published 2024-12-01
    “…But the precise mechanisms underlying its anti-inflammatory and anti-tumor effects are not fully elucidated. <b>Methods</b>: Use network pharmacology to identify targets and pathways of GQD. …”
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  19. 21719

    Good Arts, Good Mental Health®: the effectiveness of an Australian health promotion media campaign in promoting community mental wellbeing via the arts by Christina R. Davies, Melanie T. Pescud, Rhonda Clifford, Richard McGrath, Annie Thomson, Mia Jeffrey, Melissa Stoneham, Terri Pikora, Peter Wright, Sonya Girdler, Sonya Girdler, Loretta Baldassar, Stephen Clift

    Published 2025-06-01
    “…The objectives of the campaign (Wave 1) were to increase brand awareness, comprehension, and agreement with the tagline Good Arts, Good Mental Health® and empower the general population to form an intention to engage in the Arts for their mental wellbeing.MethodsThe campaign ran from August to September 2024 (4 weeks), cost AUD$198,965 (23% creative and 77% media/advertising distribution), and targeted the Western Australian (WA) general population aged 18–65 years, all genders, in both metropolitan and regional areas. …”
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  20. 21720

    A novel nomogram for predicting osteoporosis with low back pain among the patients in Wenshan Zhuang and Miao Autonomous Prefecture of China by Man Jia, Man Jia, Qinzuo Dong, Zeqin Ren, Liwei Xing, Jinjie Li, Xiaomei Wang, Shun Yu, Xiaoyan Wang, Rong Zhao, Rong Zhao

    Published 2025-06-01
    “…However, there are currently no convenient tools available to identify patients with low back pain caused by osteoporosis.MethodsWe consecutively enrolled 769 patients diagnosed with low back pain in our hospital from January 2019 to March 2024. …”
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