A Multidisciplinary Approach for the Assessment of the Last Surviving ‘Marrone di Chiusa Pesio’ Chestnut Trees in the Piemonte Region (Italy) by Giovanna Neirotti, Alessandro Tomatis, Federica Germanà, Alessia Imparato, Andrea Valisena, Maria Gabriella Mellano, Paola Ruffa, Dario Donno, Daniela Torello Marinoni, Gabriele Loris Beccaro, Giovanni Gamba

“…A multidisciplinary approach was applied, involving genetic and morphological analyses, Visual Tree Assessment (VTA), and phytochemical and nutritional profiling. …”
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A Multihead Attention Deep Learning Algorithm to Detect Amblyopia Using Fixation Eye Movements by Dipak P. Upadhyaya, MS, Gokce Cakir, MD, Stefano Ramat, PhD, Jeffrey Albert, PhD, Aasef Shaikh, MD, PhD, Satya S. Sahoo, PhD, Fatema Ghasia, MD

“…Objective: To develop an attention-based deep learning (DL) model based on eye movements acquired during a simple visual fixation task to detect amblyopic subjects across different types and severity from controls. …”
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Assessment of enthesitis in patients with psoriasis: Relationships with clinical features, screening questionnaries results, and quality of life: An ultrasound study by Dulović Dragan, Rančić Nemanja, Božić Ksenija, Stamatović Ratko, Mijušković Željko, Pešić Jasna, Kremić Zorana, Vojinović Radiša, Petronijević Milan

“…The aims of this study were to establish the prevalence of US signs of en-thesitis, compare it with screening questionnaires results, and estimate possible connections of US verified enthesitis with quality of life (QOL) of patients with psoriasis without PsA diagnosis. Methods. A cross-sectional study was performed on 67 patients with psoriasis who were without systemic therapy. …”
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TOTAL HIP ARTHROPLASTY IN PATIENTS WITH JUVENILE ARTHRITIS by D. V. Ivanov, S. A. Makarov, D. E. Karateev, V. P. Pavlov, M. A. Makarov, A. L. Logunov, I. P. Nikishina, T. A. Shelepina, V. N. Amirdzhanova

“…Prolonged hip arthritis in juvenile arthritis (JA) is a cause of serious joint destruction, leading to severe pain and functional disorders.Objective: to assess the results of total hip arthroplasty (THA) in patients with JA. Subjects and methods. The investigation enrolled 20 women and 2 men. …”
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Efficacy of fosaprepitant for the prevention of postoperative nausea and vomiting in patients undergoing gynecologic surgery: a multicenter, randomized, double-blind study by Yingjun Zhang, Xiaolin Luo, Qisen Fan, Sha Zhou, Yinqian Kang, Zhongqiao Mo, Jierong Luo, Bin Zheng, Lan Lan, Jingdun Xie

“…Abstract Purpose This study aims to investigate whether adding fosaprepitant to palonosetron and dexamethasone is effective in preventing postoperative nausea and vomiting (PONV) in high-risk patients undergoing gynecologic surgery. Methods Eligible patients undergoing gynecological surgery were randomized into two groups (1:1). …”
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Mannitol for cerebral oedema after acute intracerebral haemorrhage (MACE-ICH): protocol for a prospective, randomised, open-label, blinded-endpoint phase IIb trial by Jesse Dawson, David J Werring, Nikola Sprigg, Christine Roffe, Zhe Kang Law, Kailash Krishnan, Philip Bath, Rob A Dineen, Diane Havard, Timothy J England, Mary Joan Macleod, Stefan Pszczolkowski, Jennifer Craig, Amanda Buck, David W Hewson, Lisa Woodhouse, Fergus Doubal, Emma Grace, Keenan Wells

“…We aim to assess the feasibility of a phase II randomised, controlled trial of mannitol in patients with ICH with, or at risk of, cerebral oedema to inform a definitive trial.Methods The mannitol for cerebral oedema after acute intracerebral haemorrhage trial (MACE-ICH) aims to include 45 ICH participants from 10 UK sites with estimated largest diameter of haematoma volume >2 cm, presenting within 72 hours of onset with, or at risk of, cerebral oedema (limited Glasgow Coma Scale (GCS)<9, including motor and visual components only, and National Institutes of Health Stroke Scale>8) with or without mass effect. …”
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Arthroscopic Pectoralis Minor Release and Infraclavicular Brachial Plexus Decompression for Neurogenic Thoracic Outlet Syndrome by Eric R. Wagner, MD, MS, FAOA, Thomas J. McQuillan, MD, Oluwakorede Omole, MD, Sameer R. Khawaja, BS, Kevin R. Cuneo, BS, Zaamin B. Hussain, MD, EdM, Hayden L. Cooke, BS, Krishna N. Chopra, MA, Michael B. Gottschalk, MD, FAOA, Robert L. Bowers, DO, PhD

“…Patients showed significant improvement in visual analog scale pain (7.0-2.1) and single alpha-numeric evaluation scores (37% to 84%). …”
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Optimizing oral 3-hydroxybutyrate dosage using pharmacokinetic model to improve cognitive function and mood in healthy subjects by Kentaro Nishioka, Kentaro Nishioka, Kentaro Nishioka, Takahiro Ishimoto, Mariko Sato, Ruki Yasuda, Yumi Nakamura, Hiroshi Watanabe, Toshihide Suzuki, Yudai Araragi, Yukio Kato, Ken-ichi Yoshida, Norihito Murayama

“…Previous studies indicated that achieving a maximum concentration (Cmax) of 3-HB in plasma at 0.28 mM could initiate ketone metabolism in the brain; we hypothesized that attaining this Cmax would improve brain health.MethodsWe aimed to demonstrate the efficacy of an optimized single oral dose of 3-HB on cognitive function and mood through two clinical studies: a pharmacokinetic study and an efficacy study. …”
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Targeting ERRs to counteract age-related muscle atrophy associated with physical inactivity: a pilot study by Roberto Bonanni, Angela Falvino, Antonio Matticari, Anna Maria Rinaldi, Giovanna D’Arcangelo, Giovanna D’Arcangelo, Pierangelo Cifelli, Riccardo Iundusi, Elena Gasbarra, Virginia Tancredi, Virginia Tancredi, Ida Cariati, Umberto Tarantino

“…This study aimed to evaluate the targeting of ERRs in myoblasts isolated from the skeletal muscle of inactive women by assessing the metabolic and expression changes associated with its activation.MethodsTwenty women undergoing hip arthroplasty for coxarthrosis were enrolled and divided into an active group (n = 10) and an inactive group (n = 10) based on self-reported physical activity. …”
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A study on the status of myopia and pre-myopia among primary school students in different regions of Shaanxi Province, China by Dong Wei, Dong Wei, Li Yangbing, Liu Chengfei, Liu Chengfei, Zhang Ye, Zhang Ye, Wang Zihao, Wang Zihao, Li Yanying, Li Yanying, He Xiaokang, He Xiaokang, Fu Kunlin, Du Zhaojiang

“…Comprehensive ophthalmic examinations including uncorrected visual acuity and non-cycloplegic autorefraction were conducted. …”
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Neurotropic effects of distilled water real exposed to Kyokushin Karate katas. Neurotropic Resonance: Biophotonic Information Transfer through Kyokushin Karate-Exposed Water by Valeriy Babelyuk, Igor Popovych, Olga Smoleńska, Anna Michalska, Radosław Muszkieta, Magdalena Hagner-Derengowska, Yuriy Dobrovolsky, Galyna Dubkova, Tetyana Korolyshyn, Walery Zukow

“…This report presents data on neurotropic effects of water actually exposed to KKK. Material and methods. The study involved five male participants (aged 26-60 years, right-handed, without clinical diagnoses). …”
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Evaluation of the efficiency and safety of magnet therapy for osteoarthritis. Results of the multicenter blind placebo-controlled study COSMO (Clinical Evaluation of Current Magnet... by A. E. Karateev, E. Yu. Pogozheva, M. L. Sukhareva, A. M. Lila, A. V. Ivanov, I. P. Osnovina, O. V. Shchashkova, S. V. Borisova, N. Е. Larinsky, Yu. A. Israelyan, S. А. Afoshin, T. P. Bondarenko, E. А. Repchanskaya, L. A. Chernyavskaya, S. P. Pupina, T. V. Darmova

“…Objective: to determine the efficiency and safety of Mt for knee OA.Subjects and methods. A study group consisted of 231 patients with knee OA (77.9% were women; mean age,61.9+12.2 years; body mass index, 30.6+5.8 kg/m2; median disease duration, 5.0 [2, 0; 10.0] years). …”
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Efficacy of sensorimotor training combined with core strength training for low back pain in adult idiopathic scoliosis: a study protocol for a randomized controlled trial by Tongtong Zhang, Xin Li, Xuan Zhou, Nan Chen, Qing Du, Hong Yu, Xiaoqing Zhu, Qimeng Fan, Juping Liang, Zhengquan Chen, Xiangyue Zhou

“…This randomied controlled trial protocol aims to determine whether the combination of SoMT and CST can significantly reduce LBP, and improve scoliosis-related outcomes and overall functional status in adult idiopathic scoliosis (AdIS) patients.Methods and analysis A total of 300 AdIS patients will be recruited from the outpatient clinic and randomly assigned to one of three groups: CST group, SoMT group or the combined therapy group, using stratified block randomization based on the severity of scoliosis curve. …”
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The relationship between vitamin D levels and Alzheimer’s disease risk: insights from a centenarian study of Chinese women by Yupeng Li, Xujie Wang, Mei Yu, Fei Wang, Dong Song, Musong Liu, Xu Liang, Hongzhou Liu, Jiangbo Liu, Shihui Fu, Shihui Fu, Xuhui Liu

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Deep Learning to Predict the Future Growth of Geographic Atrophy from Fundus Autofluorescence by Anish Salvi, MS, Julia Cluceru, PhD, Simon S. Gao, PhD, Christina Rabe, PhD, Courtney Schiffman, PhD, Qi Yang, PhD, Aaron Y. Lee, MD, MSCI, Pearse A. Keane, MD, FRCOphth, Srinivas R. Sadda, MD, Frank G. Holz, MD, Daniela Ferrara, MD, PhD, Neha Anegondi, MTech

“…Purpose: The region of growth (ROG) of geographic atrophy (GA) throughout the macular area has an impact on visual outcomes. Here, we developed multiple deep learning models to predict the 1-year ROG of GA lesions using fundus autofluorescence (FAF) images. …”
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Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study by Jaesub Park, Jaesub Park, Woo Jung Kim, Woo Jung Kim, Han Wool Jung, Han Wool Jung, Jae-Jin Kim, Jae-Jin Kim, Jin Young Park, Jin Young Park, Jin Young Park

“…This study aimed to explore the relationship between regional EEG abnormalities and amyloid deposition in patients with mild cognitive impairment (MCI).MethodsWe recruited 24 older adults with MCI from a community center for dementia prevention, and 21 participants were included in the final analysis. …”
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Ibuprofen, Flurbiprofen or Naproxen Sodium Minimally Influences Musculoskeletal Adaptations to Treadmill Exercise in Rats by Brandon M. Roberts, Alyssa V. Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa N. Varanoske, Alyssa M. Kelley, Maximus C. Leiss, Alexander L. Kolb, Julie M. Hughes, Marshall A. Naimo, Ryan E. Tomlinson, Jeffery S. Staab

“…The purpose of this study was to compare the effects of three different NSAIDS: naproxen sodium, ibuprofen, flurbiprofen or a placebo on musculoskeletal adaptations in rodents with or without 6 weeks of aerobic exercise. Methods Nine‐week‐old male Wistar rats (n = 80) were randomized to either exercise (EX) or no‐exercise control (CON) conditions and treated with naproxen, ibuprofen (IBU), flurbiprofen (FLU) or placebo (PLA). …”
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Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry by Jae Myeong Kang, Manchumad Manjavong, Chengshi Jin, Adam Diaz, Miriam T. Ashford, Joseph Eichenbaum, Emily Thorp, Elizabeth Wragg, Kenton H. Zavitz, Francesca Cormack, Anna Aaronson, R. Scott Mackin, Rachana Tank, Bernard Landavazo, Erika Cavallone, Diana Truran, Sarah Tomaszewski Farias, Michael W. Weiner, Rachel L. Nosheny

“…We hypothesized that the Everyday Cognition Scale (ECog), a subjective change measure, predicts longitudinal change in cognition in the Brain Health Registry (BHR), an online registry for neuroscience research. Methods This study included BHR participants aged 55 + who completed both the baseline ECog and repeated administrations of the CANTAB® Paired Associates Learning (PAL) visual learning and memory test. …”
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Two different unilateral percutaneous vertebroplasty approaches for acute osteoporotic vertebral compression fractures: clinical and radiological outcomes by Anquan Huang, Haijun Liu, Yubo Liu, Jun Shen, Guoqing Zhu, Yefeng Wang, Shiming Li, Tianming Zou, Chenxi Gu, Bin Lv

“…Clinical efficacy indicators, including the Visual analogue scale (VAS) score and Oswestry Disability Index (ODI), were compared. …”
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Mental fatigue and sleep restriction effects on perceptual-cognitive performance in trained beach volleyball athletes by Bruno Teixeira Barbosa, Bruno Teixeira Barbosa, Bruno Teixeira Barbosa, Dalton de Lima-Junior, Alexandre Moreira, Fábio Yuzo Nakamura, Gilmário Ricarte Batista, Gilmário Ricarte Batista, Heloiana Faro, Leonardo de Sousa Fortes, Leonardo de Sousa Fortes

“…This suggests that MF and SR conditions may impair athletes’ ability to respond quickly to visual stimuli in different scenarios.…”
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