The effect of taurine supplementation on markers of muscle damage and muscle pain in an athletic population: A systematic review and meta-analysis of randomized controlled trials a... by Elaheh Dehghani, Fatemeh Naeini, Sakineh Shab Bidar, Mohammad Beba, Erfan Mortezapour, Ruhollah Nourian, Khashayar Danandeh, Zahra Gohari Dezfuli, Kurosh Djafarian

“…This systematic review and meta-analysis examines the effects of TS on EIMD and muscle pain in athletes. Methods: PubMed, Scopus, and Web of Science were systematically searched for randomized controlled trials (RCTs) on TS in athletic populations until March 2025. …”
Get full text

Factors influencing the prevalence and death rate of COPD: a pan-database ecological study covering 201 countries and regions from 1990 to 2021Research in context by Zihui Wang, Wenhan Cao, Zhixuan You, Shaoqiang Li, Mingshan Xue, Haiyang Li, Junfeng Lin, Guannan Cai, Yuqi Chen, Zhiman Liang, Chengtao Zhou, Xiaofang Wu, Guanghui Dong, Nanshan Zhong, Baoqing Sun, Zhangkai J. Cheng

“…This study aims to investigate the wide range of potential factors influencing COPD based on a pan-database ecological analysis. Methods: We integrated data from 17 global databases (e.g., the Global Burden of Disease Study) which encompass social, environmental, and health data across various regions. …”
Get full text

Disease activity in patients with idiopathic inflammatory myopathy according to time since diagnosis and positivity to antisynthetase autoantibodies: data from the Myo-Spain regist... by Tatiana Cobo-Ibáñez, Ivan Castellví, Ana Pros, Marta Domínguez-Álvaro, Laura Nuño-Nuño, Julia Martínez-Barrio, Vega Jovaní, Fredeswinda Romero-Bueno, Esther Ruiz-Lucea, Eva Tomero, Ernesto Trallero-Araguás, Javier Narváez, Jordi Camins-Fàbregas, Alberto Ruiz-Román, Jesús Loarce-Martos, Susana Holgado-Pérez, V Miguel Flores-Rodríguez, Francisca Sivera, Carolina Merino-Argumanez, Antonio Juan-Mas, Irene Altabás-González, María Martín-López, Joaquín María Belzunegui-Otano, Carmen Carrasco-Cubero, Mercedes Freire-González, Iñigo Rúa-Figueroa, Nuria Lozano-Rivas, Julio David Suarez-Cuba, Olga Martínez, Rafaela Ortega-Castro, Patricia Alcocer, Alejandro Gómez-Gómez, Olga Sánchez-Pernaute, José Luis Tandaipan, Irene Carrión-Barberà, Chamaida Plasencia-Rodríguez, Oihane Ibarguengoitia-Barrena, Paola Vidal-Montal, Vera Ortiz-Santamaria, Noemi Garrido-Puñal, Anne Riveros, Esmeralda Delgado-Frías, Juan Miguel López-Gómez, Carmen Barbadillo, José María Pego-Reigosa, Beatriz E. Joven-Ibáñez, Jesús Alejandro Valero-Jaimes, Elena Naveda, Ana Isabel Turrión-Nieves, Daniel Seoane-Mato, Francisco Javier Prado-Galbarro, M Ángeles Puche-Larrubia

“…Abstract Objective To evaluate the main outcomes of disease activity and their association with other measures of activity, damage, and quality of life in patients with idiopathic inflammatory myopathy (IIM) according to time since diagnosis and positivity to antisynthetase autoantibodies (ASAs). Methods Cross-sectional multicenter study within the Spanish Myo-Spain registry. …”
Get full text

Circulating DNA methylation level of CXCR5 correlates with inflammation in patients with rheumatoid arthritis by Yiming Shi, Cen Chang, Lingxia Xu, Ping Jiang, Kai Wei, Jianan Zhao, Linshuai Xu, Yehua Jin, Runrun Zhang, Huijuan Wang, Yi Qian, Yingying Qin, Qin Ding, Ting Jiang, Shicheng Guo, Rongsheng Wang, Dongyi He

“…Abstract Objectives To assess the differences in circulating DNA methylation levels of CXCR5 between rheumatoid arthritis (RA) and osteoarthritis (OA) and healthy controls (HC), and the correlation of methylation changes with clinical characteristics of RA patients. Methods Peripheral blood samples were collected from 239 RA patients, 30 patients with OA, and 29 HC. …”
Get full text

Implementing a Common Data Model in Ophthalmology: Mapping Structured Electronic Health Record Ophthalmic Examination Data to Standard Vocabularies by Justin C. Quon, MD, Christopher P. Long, MD, William Halfpenny, MBBS, MEng, Amy Chuang, MS, Cindy X. Cai, MD, MS, Sally L. Baxter, MD, MSc, Vamsi Daketi, MS, Amanda Schmitz, BS, Neil Bahroos, MS, Benjamin Y. Xu, MD, PhD, Brian C. Toy, MD

“…Subjects: Not applicable. Methods: Source eye examination data elements from the default Cerner Model Experience EHR and a local implementation of the Cerner Millennium EHR were extracted, classified into one of 8 subject categories, and mapped to the semantically closest standard concept in the OMOP CDM. …”
Get full text

Evidence of functional connectivity disruptions between auditory and non-auditory regions in adolescents living with HIV by Joanah Madzime, Joanah Madzime, Marcin Jankiewicz, Marcin Jankiewicz, Marcin Jankiewicz, Ernesta M. Meintjes, Ernesta M. Meintjes, Ernesta M. Meintjes, Peter Torre, Barbara Laughton, Martha J. Holmes, Martha J. Holmes, Martha J. Holmes, Martha J. Holmes

“…Investigating the functional connectivity (FC) within the CAS and between the CAS and non-auditory regions may reveal the influence of HIV on regions involved in auditory function.MethodsWithin a Bayesian statistical framework, we used resting-state functional magnetic resonance imaging to map FC in the CAS as well as between CAS regions and non-auditory regions of 11-year-old CPHIV. …”
Get full text

16 weeks of moderate intensity resistance exercise improves strength but is insufficient to alter brain structure in Gulf War Veterans with chronic musculoskeletal pain: a randomiz... by Stephanie M. Van Riper, Jacob V. Ninneman, Jacob V. Ninneman, Aaron J. Stegner, Aaron J. Stegner, Brady A. Riedner, Brady A. Riedner, Laura D. Ellingson, Ryan J. Dougherty, Patrick J. O’Connor, Gunnar A. Roberge, Gunnar A. Roberge, Andrew L. Alexander, Andrew L. Alexander, Andrew L. Alexander, Doug C. Dean, Doug C. Dean, Doug C. Dean, Jill N. Barnes, Dane B. Cook, Dane B. Cook

“…This study tested the effects of 16 weeks of resistance exercise training (RET) on gray matter (GM) volume and white matter (WM) microstructure in Gulf War Veterans (GWVs) with CMP compared to GWV waitlist controls (WLC).MethodsFifty-four GWVs were randomly assigned to 16 weeks of RET (n = 28) or WLC (n = 26). …”
Get full text

Group Psychological Therapy Program in Adult Patients with Congenital Heart Disease and Anxious–Depressive Symptoms by Efrén Martínez-Quintana, Karen Codana-Alcántara, Hector M. Montesdeoca-Naranjo, Marta Isabel García-Suárez, María Pino Fleitas-Álvarez, María Alcántara-Castellano, Alejandro Ruiz-Castellano, Ana González-Isasi, Fayna Rodríguez-González, Esperanza Bosch-Casañas

“…As group therapy has proven to be a valuable and effective treatment option for managing anxiety and depression, the aim of this study was to determine its effects on patients with CHD and anxious–depressive symptoms. <i>Methods</i>: We used non-pharmacological psychological group intervention, of six weekly sessions of 90 min each, administered by trained personnel, in adult patients with CHD. …”
Get full text

Assessment of the diagnostic utility of the electroencephalogram in pediatric emergencies by M.J. Abenza Abildúa, T. Olmedo Menchen, A. Pérez Villena, S. Ruhland Paulete, F.J. Navacerrada Barrero, J. de Ojeda Ruíz de Luna, C. Algarra Lucas, G. Cordero Martín, S. Martínez Ubierna, C. Jimeno Montero, I.J. Navarro López, E. Suárez Gisbert, Á. Gómez de la Riva, C. Pérez López, M.L. Herreros Fernández

“…Introduction: We analyze the diagnostic utility of urgent EEG (electroencephalogram) performed in children under 16 years of age in our center. Material and methods: Descriptive, retrospective, observational study of consecutive patients from 0 to 16 years of age, who underwent an urgent EEG for any reason, from January to December 2022. …”
Get full text

Refractive status and ocular characteristics of preschool children with retinopathy of prematurity after different treatments by Wu-Yang Jiang, Man-Hong Li, Hao Wang, Dong Niu, Yu-Sheng Wang, Zi-Feng Zhang

“…AIM: To compare the changes in preschool refractive status, ocular biological parameters, and higher-order aberrations in children with retinopathy of prematurity (ROP) after retinal laser photocoagulation or anti-vascular endothelial growth factor (anti-VEGF) treatment and explore their underlying factors. METHODS: This observational study involved 118 eyes of 59 children, aged 3 to 6y, with ROP followed up between March 2023 and October 2024. …”
Get full text

FEATURES OF LOCAL IMMUNITY IN PATIENTS WITH OROPHARYNGEAL CANCER by O. I. Keith, M. N. Tilliashaihov, P. V. Svetitsky, E. Yu. Zlatnik, G. I. Zakora, A. A. Ganiev, G. P. Nistratov

“…This makes it necessary to improve the methods of its diagnosis and treatment. Modern laboratory techniques allow predicting patient’s condition before and during the course of treatment; they were implemented into clinical practice for successful treatment correction. …”
Get full text

Comparative analysis of clinical efficacy of unilateral biportal endoscopic and open transforaminal lumbar interbody fusion in the treatment of lumbar degenerative by Tao Ma, Xiaoshuang Tu, Junyang Li, Yongcun Geng, Yongcun Geng, Jingwei Wu, Senlin Chen, Dengming Yan, Dengming Yan, Ming Jiang, Ming Jiang, Gongming Gao, Luming Nong

“…Clinical efficacy was assessed preoperatively and at 1 month, 3 months, and 12 months postoperatively using the Visual Analogue Scale (VAS) and the Oswestry Disability Index (ODI). …”
Get full text

Metabolism and Microstructure of the Small Intestine Wall in Patients With Colorectal Cancer by M. V. Bagryantsev, M. G. Ryabkov, E. L. Bederina, M. M. Loginova, A. V. Bazayev, A. I. Abelevich, I. L. Dezortsev, S. S. Bunova, M. V. Shirmanova, V. I. Shcheslavskiy, E. B. Kiseleva

“…Bioimaging technologies, namely, methods of optical coherence tomography and fluorescence lifetime macroimaging, made it possible to objectively display microstructural and metabolic disorders in the ileum wall. …”
Get full text

Prevalence of Refractive Errors Among School-Age Children and Adolescents in Saudi Arabia: A Systematic Review and Meta-Analysis by Al Khathami A, Baklola M, Alshehri AA, Alnasser LH, Alshehri RS, Salawi MA, Alwadai RH, Al Ghazwi M, Alanazi AAQ, Alshammari AM, Al-bawah N, Hafez M, Abu Melha A

“…While studies using cycloplegic refraction reported a slightly higher myopia prevalence (7.2%, 95% CI: 4.7% to 11%) than those using non-cycloplegic methods (6.7%, 95% CI: 2.4% to 17.5%), the difference was not statistically significant (p = 0.9). …”
Get full text

Metabolomic Profiling of the Blood of Patients with Chronic Consciousness Disorders by A. A. Orlova, E. A. Kondrat'eva, Ya. A. Dubrovskii, N. V. Dryagina, E. V. Verbitskaya, S. A. Kondratev, A. A. Kostareva, A. N. Kondratev

“…The aim of the study was to investigate the main differences in metabolomic abnormalities in patients with VS / UWS and MCS, as well as to identify changes in metabolomics depending on sleep or wakefulness phase.   Materials and Methods. Untargeted metabolome analysis of blood plasma of 10 patients in VS / UWS (group 1) and 6 patients in MCS (group 2) was performed using reversed-phase and hydrophilic chromatography methods. …”
Get full text

Photon counting detector CT-derived virtual non-contrast images of the liver: comparison of conventional and liver-specific algorithms across arterial and portal venous phase scans by Anna-Katharina Gerstner, Franka Risch, Luca Canalini, Gerlig Widmann, Elke R. Gizewski, Stefanie Bette, Simon Hellbrueck, Thomas Kroencke, Josua A. Decker

“…Bland-Altman plots were utilised to visually assess the agreement between results and Passing-Bablok regression, thereby quantifying the observed agreement. …”
Get full text

Research Progress on the Impact of Nighttime Outdoor Environments on Residents’ Health by Chongxian CHEN, Xinrui XIONG, Guangsi LIN, Jingyi LIU

“…The ultimate goal is to provide a scientific foundation for health-oriented nighttime urban planning and policymaking.MethodsThis research conducts a comprehensive review of Chinese and English literature on nighttime outdoor environments and public health, using publications retrieved from the Web of Science (WoS) and China National Knowledge Infrastructure (CNKI) databases that span the period from 1999 to 2025. …”
Get full text

From background diabetic retinopathy to its proliferative stage. What is the role of gut microbiota in the trajectory of DR? a Mendelian randomization study with mediation analysis by Yifan Zhou, Jialong Dong, Zhenyu Wang, Chen Huang, Xiaotong Yu, Xinjun Wang, Bo Yang, Yuechen Wu, Qing Peng

Get full text

Pragmatic Randomized Controlled Trial of Pharmacopuncture Therapy for Cervical Disc Herniation: A Pilot Study by Lee SW, Ahn YJ, Kim S, Lee Y, Cho HW, Hong Y, Nam D, Park YC, Kim EJ, Lee YJ, Ha IH

“…Although pharmacopuncture therapy is one of the most widely used treatment methods for CDH in Korean medicine clinical practice, there are few high-quality studies conducted in Korea. …”
Get full text

Influence of dendritic cells on corneal nerve morphological analysis and clinical relevance in chronic dry eye disease after femtosecond laser-assisted laser in situ keratomileusis by Yilin Liu, Yilin Liu, Baikai Ma, Baikai Ma, Lu Zhao, Hongshuo Li, Wenlong Li, Wenlong Li, Zhengze Sun, Zhengze Sun, Hongyu Duan, Hongyu Duan, Yitian Zhao, Hong Qi, Hong Qi

Get full text