Short-term outcomes of faricimab and aflibercept 8 mg in diabetic macular edema by Carlo Maccauro, Yanny Jimenez Perez, Piergiorgio Neri, Ibraheem El Ghrably, Haytham I Salti, Francesco Pichi

“…Primary outcomes included changes in best-corrected visual acuity (BCVA) measured in logarithm of the minimum angle of resolution (logMAR), central retinal thickness (CRT) assessed via optical coherence tomography (OCT), and the number of injections required. …”
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Chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels: a network analysis on 2018 CHARLS data by Qiaofeng LI, Yilong YAN, Yuehan HE, Yongtai LI, Guowu DING

“…ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment. MethodsData from 14 222 middle-aged and elderly individuals aged ≥ 45 years old were collected from the 2018 China Health and Retirement Longitudinal Study (CHARLS). …”
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Dry Eye Epidemiology in Patients before Refractive Operations by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Y. A. Kalantaevskaya, R. A. Ismaylova, E. M. Ehieva, M. V. Grishenko, I. V. Gorbunova, O. F. Ozhug, O. A. Klokova

“…To evaluate the prevalence, clinical severity, clinical and pathogenetic variants and etiology of dry eye (DE) in patientsbefore refractive surgery. Methods. OSDI testing, lipid interferential test, TBUT, Shirmer-1, -2 tests, compression Norn test in Korbmodification, calculation of xerosis index by Bijsterveld, tear meniscus index evaluation, LIPCOF test, evaluation of epitheliopaty and microerosion by Tseng and lid viper epitheliopaty were performed in 600 myopia (with or without astigmatism) patients (234 men, 366 women; 30.1 ± 6.26 years old) before refractive surgery. …”
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Comparative study on the quality of life and clinical efficacy of orthokeratology lens, defocus spectacle lens and single vision spectacles in myopic children and adolescents in Ch... by Sile Yu, Wei He, Yang Li, Tingting Zhao, Li Lin, Xiaonan Liu, Jiayan Chen, Guanghao Qin, Xingru He, Ruyi Li, Yibing Zhou

“…The Pediatric Refractive Error Profile questionnaire was used to compare the visual-related quality of life after 1 year of lens wear among the three groups. …”
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Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer's disease mediated by upregulation of BDNF and NGF and downre... by Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A.O.A. Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono

“…Interactions between the main substances of BUMSC-CM and beta-amyloid protein were visualized using in silico molecular docking. Results: Our result demonstrated that BUMSC-CM with the dosage of 0,5 ml/kg BW significantly increased BDNF concentration. …”
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Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study by Erika Endzelytė, Daiva Petruševičienė, Raimondas Kubilius, Sigitas Mingaila, Jolita Rapolienė, Inesa Rimdeikienė

“…We hypothesized that integrating BCI into occupational therapy would result in measurable improvements in hand strength, dexterity, independence in daily activities, and cognitive function compared to baseline. <i>Materials and Methods</i>: An observational study was conducted on 56 patients with subacute stroke. …”
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Investigating the Efficacy and Safety of the CyberKnife System for Treating Primary Pancreatic Cancer with Metastases to the Gastrointestinal Tract by Zhang Z, Tian B, Xu H, Huang H, Liang X, Bo C, Bian Y, Wei M, Zhao Z

“…The median OS was 8.17 months (range: 1– 25 months). Mean pain scores (Visual Analog Scale) decreased significantly from 5.38± 1.37 at baseline to 2.01± 0.35 post-treatment (p&lt; 0.001). …”
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Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…This study offers a genomic analysis of C. difficile, focusing on sequence types (STs), global distribution, antibiotic resistance genes, and virulence factors in its chromosomal and plasmid DNA.MethodsA total of 19,711 C. difficile genomes were retrieved from GenBank. …”
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Effects of single subanesthetic dose of oxycodone on pain and Th1/Th2 balance in patients after radical mastectomy by QU Na，ZHAO Xiaohong，NI Qiang

“…Objective To compare the effects of oxycodone and fentanyl on postoperative pain relief，immune balance of T-helper cells（Th），and adverse reactions in radical mastectomy. Methods A total of 120 female patients whounderwent elective radical mastectomy at Shanghai Public Health Clinical Center between December 2021 and January2024 were selected for this study. …”
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Effects of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression in the treatment of avascular necrosis of femoral he... by Lei Sun, Ziyao Xu, Zhongyuan Zhang, Jinwei Zhao, Mengshuai Sun, Guangling Gao, Fang Gao, Hongjiang Jiang, Changjun Ju

“…The objective of this study is to evaluate the effect of PRP injection combined with intersecting femoral head decompression versus combined with multiple core decompression (MCD) in the treatment of ANFH. Methods A retrospective cohort analysis comparing two surgical interventions was conducted between January 2020 and December 2020. …”
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Qualitative and quantitative ultrasound parameters of carotid atherosclerotic plaques in patients with moderate cardiovascular risk according to the SCORE scale: 7-year prospective... by O. A. Pogorelova, M. I. Tripoten, I. S. Melnikov, L. Sh. Khamchieva, B. M. Tamaeva, S. G. Kozlov, T. V. Balakhonova

“…Plaque number, maximum plaque height, total plaque height, total CA stenosis, visual plaque morphology, gray-scale median (GSM), and intima- media thickness of the right and left common CAs were assessed. …”
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Comparison of Milligan-Morgan Haemorrhoidectomy versus Laser Haemorrhoidoplasty in Patients with Grade II and III Haemorrhoids: A Prospective Observational Study by Asfar Ahamed Nawabjan, Sathish Rajkumar, Chudar Arumugam, Mohamed Marzook, Jasmine Sharmila, Lalith Kumar

“…The laser group had significantly lower postoperative pain {Visual Analogue Scale (VAS) 4.60±1.14 vs. 9.15±0.67 on Day 1, p<0.001}, shorter operative time (19.85 min vs. 54.75 min), reduced intraoperative blood loss (7±2.51 mL vs. 23±5.23 mL, p<0.001), and shorter hospital stay (1.1 vs. 1.85 days, p<0.001). …”
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Anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids by Yuan Ke, Lei Yinfu, Chen Lina, Yu Lelai, Liu Huan, Shen Qingbo, Huang Qi, Pei Xi

“…[Objectives] To investigate the effect of anatomical hemorrhoidectomy and semi-shutting suture combined with mucosal ligation for mixed hemorrhoids. [Methods] Eighty patients with mixed hemorrhoids treated at our hospital between May 2019 and May 2020 were recruited and randomly assigned to the treatment and control group using the random number table. …”
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Safety and efficacy of robot-assisted percutaneous kyphoplasty under local anesthesia in a day-surgery setting for osteoporotic vertebral compression fractures by Yaming Wu, Yang Yuan, Yi Yin, Yaqin Gong, Yaowei Ye, Li Wu, Lizhen Qian

“…This retrospective study evaluates the safety and efficacy of robot-assisted percutaneous kyphoplasty (PKP) performed under local anesthesia within a day-surgery framework.MethodsClinical data from 127 patients with OVCFs who underwent robot-assisted PKP under local anesthesia in a day-surgery setting at the First People's Hospital of Kunshan between May 2022 and April 2024 were retrospectively analyzed. …”
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Knowledge of telemedicine and its associated factors among health professional in Ethiopia: A systematic review and meta-analysis. by Adamu Ambachew Shibabaw, Alex Ayenew Chereka, Agmasie Damtew Walle, Addisalem Workie Demsash, Geleta Nenko Dube, Abiy Tasew Dubale, Sisay Yitayh Kassie, Gemeda Wakgari Kitil, Mesafint Zewold Jember, Chernet Desalegn Gebeyehu, Aster Temesgen Ariger, Eshetie Andargie Dires

“…The funnel plot was visually inspected, and Egger's regression test was run to check for publication bias. …”
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Noninferiority of 0.25% versus 0.375% Ropivacaine in Popliteal Sciatic and Saphenous Nerve Blocks for Analgesia After Foot and Ankle Surgery: A Randomized Self-Paired Noninferiorit... by Wu L, Xi C, Lei G, Li H, Yin Y, Wan M, Wu H, Wang Y, Hu C, Wang G

“…Hence, we hypothesized that the analgesic effect of 0.25% ropivacaine would be noninferior to that of 0.375% ropivacaine at the same volume and would reduce the degree of weakness.Patients and Methods: In this randomized, double-blind, self-paired, noninferiority trial, 31 patients who were scheduled for similar, elective, bilateral foot and ankle surgeries under general anesthesia combined with popliteal sciatic and saphenous nerve blocks were enrolled. …”
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Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The &ldquo;Village Bondeko&rdquo; Center, In Kinshasa by Masamba GR, Sokolo Gedikondele J, Longo-Mbenza B, Nganga Nkanga MS, Matanda Nzanza R, Matonda-ma-Nzuzi T, Ikanga J, Nge Okwe A, Lema Mabwaka G, Mawalala Malengele H, Nangi Mampuya C, Lumbu Malundama D

“…Thus, the objective of the present study was to investigate the relationship between sensorineural hearing loss and cognitive disorders in a correlational approach.Methods: This is a cross-sectional and analytical study conducted in the ENT department of the Center for the Disabled (visual, auditory, and mental) “Village Bondeko”, from June to September 2023, involving 150 adults (≥ 20 years) with acquired sensorineural hearing loss; without a history of neuropsychic disorders. …”
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Assessment of publication time in Campbell Systematic Reviews: A cross‐sectional survey by Bei Pan, Long Ge, Xiaoman Wang, Ning Ma, Zhipeng Wei, Lai Honghao, Liangying Hou, Kehu Yang

“…There was no significant difference between Campbell coordinating groups' median publication times and time gap from searches of databases to full review publication existed. However, the methods group only published one full review with almost a 3‐year time gap from searches of databases to review publication. …”
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Analysis of clinical knowledge, absenteeism and availability of resources for maternal and child health: a cross-sectional quality of care study in 10 African countries by Laura Di Giorgio, David K Evans, Magnus Lindelow, Son Nam Nguyen, Jakob Svensson, Waly Wane, Anna Welander Tärneberg

“…Objective Assess the quality of healthcare across African countries based on health providers’ clinical knowledge, their clinic attendance and drug availability, with a focus on seven conditions accounting for a large share of child and maternal mortality in sub-Saharan Africa: malaria, tuberculosis, diarrhoea, pneumonia, diabetes, neonatal asphyxia and postpartum haemorrhage.Methods With nationally representative, cross-sectional data from ten countries in sub-Saharan Africa, collected using clinical vignettes (to assess provider knowledge), unannounced visits (to assess provider absenteeism) and visual inspections of facilities (to assess availability of drugs and equipment), we assess whether health providers are available and have sufficient knowledge and means to diagnose and treat patients suffering from common conditions amenable to primary healthcare. …”
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Effectiveness of telerehabilitation in non-operatively managed shoulder conditions: a systematic review and meta-analysis by Ting-wan Lin, Yang Yang, Hai-yan Hong, Xiao-bo Zhou, Tao-Hsin Tung, Bin-bin Zheng, Jian-min Zhang

“…However, its overall efficacy remains uncertain due to inconsistent findings in prior studies. Methods This systematic review and meta-analysis assessed the effectiveness of telerehabilitation for non-operatively managed shoulder conditions, concentrating on randomized controlled trials (RCTs). …”
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