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21481
Regular use of non-steroidal anti-inflammatory drugs can effectively control pain and global health in patients with moderate activity of rheumatoid arthritis
Published 2021-04-01“…In particular, this concerns the effect of NSAIDs on the inflammatory activity of the disease.Objective: to study the comparative efficacy and safety of NSAIDs in RA patients with moderate and low disease activity.Patients and methods. The study group consisted of 404 patients with RA, 69% women and 31% men, mean age 58.6±10.0 years, with moderate and low disease activity – DAS28<5.1 (mean value 3.7±1.5), who initially had moderate or severe pain: >4 cm on the visual analog scale (VAS) 0–10 cm. …”
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21482
Left ventricular segmental strain based on speckle tracking echocardiography versus indications of immune inflammation in patients after COVID-19 pneumonia
Published 2023-06-01“…Objective — To examine the association of echocardiographic parameters with indications of immune inflammation in patients recovered from COVID-19 pneumonia depending on segmental longitudinal strain (LS) of the left ventricle (LV) identified by STE. Methods — Our study encompassed 216 patients (51.1% men, mean age of 50.1±11.1 years) distributed among two groups: Group I (n=108) included study subjects with segmental LS (≥3 LV segments) revealed by the STE; Group II (n=108) comprised patients without visually detectable LV lesions. …”
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21483
A Pilot Study of Virtual Reality in Hemodialysis for Mitigating Pain and Anxiety: User Experiences and Perceptions
Published 2025-07-01“…This study analyzes VR’s effect on pain and anxiety in hemodialysis (HD) patients at two points: the vascular access puncture and disconnection.Methods: A prospective, non-randomized, crossover, multicenter pilot study assessing pre- and post-intervention outcomes with VR headsets. …”
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21484
How intravitreal anti-vascular endothelial growth factor initial dosing impacts patient outcomes in diabetic macular oedema
Published 2024-12-01“…Characteristics, treatment patterns and outcomes were compared for eyes with DME that did and did not receive such initial doses. Methods This was a retrospective database study using American Academy of Ophthalmology Intelligent Research in Sight® Registry data (01/01/15–31/12/20; index period). …”
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21485
The role of magnesium deficiency correction in the rehabilitation of women with climacteric syndrome and surgical menopause: results of the MAGYN study
Published 2023-01-01“…There were analyzed general somatic pathology, complaints, symptoms of magnesium deficiency by using visual analog scale, as well as the data of drug therapy, including a combination of magnesium citrate + vitamin B6 (pyridoxine) applied for 4 weeks.Results. …”
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21486
Dysgeusia in MASLD-related advanced chronic liver disease (ACLD): a silent driver towards the “Bermuda” triangle of malnutrition-sarcopenia-frailty severely affecting prognosis
Published 2025-01-01“…Dysgeusia was assessed by the Dysgeusia-Total-Score (DTS). A visual analog scale identified appetite impairment (VASAI). …”
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21487
Geostatistics Precision Agriculture Modeling on Moisture Root Zone Profiles in Clay Loam and Clay Soils, Using Time Domain Reflectometry Multisensors and Soil Analysis
Published 2025-07-01“…Two different sensor calibration methods (M1 and M2) were trialed, as well as the results of laboratory soil analysis for geospatial two-dimensional (2D) imaging for accurate GIS maps of root zone moisture profiles, granular, and hydraulic profiles in multiple soil layers (0–75 cm depth). …”
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21488
Combining an internal tension relieving technique with anterior cruciate ligament reconstruction (ACLR) reduces graft failure rate and improves functional outcomes: a systematic re...
Published 2025-01-01“…The purpose of this study is to compare the graft failure rates and clinical functional outcomes between ITRT-assisted ACLR and conventional ACLR. Methods Following the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines, a search was conducted in databases including Ovid, PubMed, Web of Science, Embase, Cochrane Library, Wanfang Data, CNKI, and VIP Medical Database for clinical controlled trials comparing the ITRT combined with ACLR to conventional ACLR. …”
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21489
Machine Learning Model for Early Detection of COVID-19 by Heart Rhythm Abnormalities
Published 2023-07-01“…The possibility of integrating the results obtained with fitness bracelets and smart watches is shown.Materials and Methods. The work involved an open technology stack: Python, Scikit-learn, Lightgbm. …”
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21490
Prognostic factors associated with achieving minimal disease activity in early psoriatic arthritis patients treated according to “treat-to-target” st rategy within 12 months
Published 2022-12-01“…But prognostic factors for achievement MDA in PsA patients (pts) at the early-stage hasn’t been studied yet.Objective – to determine the prognostic factors associated with achievement of minimal disease activity within 12 months (mo) of treatment according to T2T strategy in early psoriatic arthritis patients.Methods. 77 pts (M/F=36/41) with early PsA fulfilling the CASPAR criteria were included. …”
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21491
Effects of varying longitudinal bending stiffness in running shoes on lower limb biomechanics of elite marathon runners
Published 2025-05-01“…ObjectiveThis study examined the effect of three levels of longitudinal bending stiffness (LBS) in carbon-plated shoes on lower limb biomechanics.MethodsFifteen elite male marathon runners, each with a personal best under 3 h, participated in the study. …”
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21492
Fluorine-18-Labeled Positron Emission Tomography Probe Targeting Activated p38α: Design, Synthesis, and In Vivo Evaluation in Rodents
Published 2025-04-01“…This study aimed to develop and evaluate a novel fluorine-18-labeled positron emission tomography (PET) probe for imaging activated p38α in vivo. <b>Methods:</b> We designed 6-(4-[<sup>18</sup>F]fluoro-2-fluorophenoxy)-8-methyl-2-(tetrahydro-2<i>H</i>-pyran-4-ylamino)-pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-one ([<sup>18</sup>F]R1487) by replacing a fluorine atom in R1487, which is a highly selective p38α inhibitor, with <sup>18</sup>F. …”
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21493
Unilateral biportal endoscopy versus percutaneous endoscopic lumbar discectomy for lumbar disc herniation: a comparative study of clinical efficacy and radiological outcomes
Published 2025-07-01“…The aim of this study is to compare the clinical efficacy and radiological outcomes between UBE and PELD in the treatment of LDH. Methods A retrospective analysis was conducted on 108 patients with LDH treated with spinal endoscopy in our hospital from January 2021 to July 2023. …”
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21494
Association of Serum Uric Acid With Relative Muscle Loss: A US Population–Based Cross‐Sectional Study
Published 2025-06-01“…We sought to investigate the association of SUA levels with relative muscle loss in the National Health and Nutrition Examination Survey (NHANES) 2011–2018. Methods Relative muscle loss was defined by the Foundation for the National Institutes of Health (FNIH) as characterized by appendicular lean mass (ALM) adjusted by BMI (ALM/BMI) < 0.512 for women and < 0.789 for men. …”
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21495
Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer...
Published 2025-07-01“…Pre- and post-intervention assessments included pain (Visual Analog Scale, VAS), patient-reported outcomes (Knee Injury and Osteoarthritis Outcome Score, KOOS), physical function tests (30-second sit-to-stand, 40-meter fast-paced walk, stair climb, timed up-and-go), and knee muscle strength and core endurance. …”
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21496
Midterm Outcomes of Transfibular Total Ankle Arthroplasty: Clinical and Radiographic Analysis of 130 Cases with Minimum 5-Year Follow-Up
Published 2024-12-01“…Here we present the largest midterm study to date by a single-surgeon, and analyze the survivorship, clinical, and radiographic outcomes of the transfibular TAA at a minimum of 5-years follow-up. Methods: Retrospective review was performed on prospectively followed patients who underwent primary transfibular TAA by a single surgeon from October 2012 to December 2018. …”
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21497
Clinical efficacy of one-hole split endoscopy vs. unilateral biportal endoscopy for the treatment of single-segment lumbar spinal stenosis: a retrospective study with 2-year follow...
Published 2025-02-01“…This study aimed to compare the long-term efficacy of OSE and unilateral biportal endoscopy (UBE) in LSS treatment.MethodsThe clinical data of 77 patients diagnosed with LSS at our hospital between January 2020 and March 2022 were retrospectively analyzed. …”
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21498
Validity and Feasibility of the Seated Medicine Ball Throw and Unilateral Shot-Put Tests in Assessing Upper Extremity Function in Rotator-Cuff-Related Shoulder Pain
Published 2024-12-01“…Pain was assessed using a 10 cm visual analog scale (VAS) at multiple time points. …”
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21499
Comparative Efficacy of Different Exercise Therapies for Cardiorespiratory Fitness in Breast Cancer Survivors: A Systematic Review and Bayesian Network Meta-analysis
Published 2025-06-01“…A network graph was constructed to visualize the relative relationship for each exercise therapy in relation to the others. …”
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21500
Quantitative analysis of retinal vascular parameters changes in school-age children with refractive error using artificial intelligence
Published 2024-12-01“…All participants underwent a series of examinations, including naked-eye and best-corrected visual acuity, cycloplegic spherical equivalent refraction, intraocular pressure measurement, ocular axial measurement (AL), and color fundus photography. …”
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