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21421
Meta-analyses of the effects of high-intensity interval training in elite athletes — part II: relationships between the mean effects on various performance measures
Published 2024-12-01“…Here, we extend the analyses to relationships between mean changes of these measures and consider implications for understanding and improving HIIT that were not apparent in the previous analyses.MethodsThe data were mean changes from HIIT with highly trained endurance and elite other (mainly team sport) athletes in studies where two or more measures or predictors of performance were available. …”
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21422
Effects of plant active substances in rheumatoid arthritis—a systematic review and network meta-analysis
Published 2025-02-01“…The main focus was on assessing primary outcomes, including the Visual Analogue Scale (VAS), inflammatory markers, Swollen Joint Count (SJC), Tender Joint Count (TJC), and Disease Activity Score on 28 joints (DAS28). …”
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21423
The burden of refraction disorders in 204 countries and territories from 1990 to 2021: A systematic analysis from the global burden of disease 2021
Published 2025-05-01“…Background: Refraction disorders are common eye conditions that cause blurred vision and, if left uncorrected, remain a leading cause of moderate to severe visual impairment worldwide. Despite this, a comprehensive assessment of the associated burden is lacking. …”
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21424
Effect of superficial cervical plexus nerve block with Ropivacaine or a combination of different adjuvants on perioperative analgesia and quality of postoperative recovery in patie...
Published 2025-03-01“…The primary observation index were postoperative resting and active Visual Analogue Score. The secondary observation index were hemodynamics, intraoperative sedative and analgesic medication use, postoperative analgesic requirements, postoperative recovery indicators, Richards-Campbell Sleep Questionnaire scores, Quality of Postoperative Recovery-15 scores, and adverse reactions. …”
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21425
Differential effects of sound interventions tuned to 432 Hz or 443 Hz on cardiovascular parameters in cancer patients: a randomized cross-over trial
Published 2025-01-01“…Abstract Background This study investigated whether a sound intervention tuned to 432 Hz (Hz) yields differential effects on cardiovascular parameters and psychological outcomes compared to 443 Hz, which is the concert pitch in German professional orchestras. Methods Using a randomized cross-over design, patients with cancer were recruited to receive both a 15-minute sound intervention with a body monochord tuned to 432–443 Hz. …”
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21426
Metformin treatment for patients with hand osteoarthritis: protocol for the multicentre, randomised, placebo-controlled METRO trial
Published 2025-03-01“…The primary endpoint is the between-group difference in least squares means for the change in the Visual Analogue Scale (VAS) finger joint pain scores between the metformin and placebo groups at 16 weeks. …”
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21427
Neurophysiological findings in Attention Deficit Hyperactivity Disorder, a Pandora’s box with therapeutic implications
Published 2025-03-01“…This study aimed to identify dysfunctional mechanisms behind ADHD symptoms and test if targeting these dysfunctions can improve clinical outcomes. Methods: 230 children with ADHD diagnosis studied with hypothesis-related variables from electroencephalogram (EEG) visual inspection and quantitative z-scored power, coherence and ratios, and from event-related brain potentials (ERPs) z-sored P50, N100, N200, P300 latencies amplitudes and ratios. …”
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21428
Efficacy of repetitive transcranial magnetic stimulation for smoking cessation: a systematic review and meta-analysis
Published 2025-07-01“…Objective To evaluate the efficacy of rTMS in smoking cessation, its impact on abstinence rates, nicotine dependence, and craving. Methods We conducted a comprehensive search across multiple databases (PubMed, Scopus, Web of Science, Cochrane, PsycINFO, and Clinicaltrials.gov) from inception to August 2024. …”
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21429
Anterior lumbar interbody fusion with a novel osteoinductive allograft – Mid-term clinical and radiographic outcomes
Published 2025-04-01“…Patient reported outcome measures included visual analog scale (VAS) back pain, Oswestry disability index (ODI) and 12-Item Short Form Survey (SF-12) measured at preoperative, 6-week, 6-month, 12-month, and 24-month time points. …”
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21430
Anterior cervical discectomy and fusion in treating acute myelopathy caused by Brucella cervical spondylitis: a case series
Published 2025-12-01“…This study aims to begin to investigate the clinical characteristics of acute cervical myelitis caused by Brucella infection and to evaluate the profile of clinical benefit of anterior cervical discectomy and fusion (ACDF) for this condition.Methods This retrospective case series included 6 patients who underwent surgical treatment for acute cervical spinal cord impairment due to Brucella infection at our institution between January 1, 2013, and January 1, 2023. …”
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21431
Multimodal Analgesia Approach in Acute Low Back Pain Management: A Phase III Study of a Novel Analgesic Combination of Etoricoxib/Tramadol
Published 2024-09-01“…The proportion of patients with a 30% reduction in Visual Analogue Scale (VAS) score was statistically significant when comparing the treatment groups on the third day of follow-up [p = 0.008, CI 95% 0.241 (0.061–0.421)]. …”
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21432
Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study
Published 2024-08-01“…Background/aims This study aimed to investigate and compare the efficacy and safety of first-line and second-line selective laser trabeculoplasty (SLT) in Japanese patients with normal-tension glaucoma (NTG).Methods 100 patients with NTG were enrolled in this study. …”
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21433
Individual-level characteristics and geospatial factors associated with cervical cancer screening participation in Alberta, Canada: a population-based cross-sectional study
Published 2025-08-01“…This study aimed to identify these characteristics related to cervical cancer screening status. Methods The study population included women between the ages of 28 to 69 years in Alberta. …”
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21434
Focal liver lesions: multiparametric microvasculature characterization via super-resolution ultrasound imaging
Published 2024-12-01“…Methods Patients with FLLs between June 2022 and February 2023 were prospectively screened. …”
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21435
Combinations of polymorphisms in the regulatory regions of cytokine genes are associated with diabetic retinopathy in type 2 diabetic patients
Published 2018-01-01“…Accordingly, we aimed to assess the frequencies of combinations of SNPs from promoters of cytokine genes in type 2 diabetic subjects with and without DR.Materials and methods: We enrolled 201 caucasian subjects with type 2 diabetes, including 90 ones with non-proliferative or preproliferative retinopathy and 111 subjects without DR. …”
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21436
The Swiss Endometriosis Database: a retrospective multicentre cohort study on pain levels and multimodal treatment needs of endometriosis patients
Published 2025-06-01“… STUDY AIMS: This study aimed to deepen the understanding of endometriosis symptoms, types, and therapy recommendations for Swiss endometriosis patients in Swiss-certified endometriosis centres in 2022. METHODS:In this exploratory retrospective multicentre cohort study, data from 3538 women who had their first consultation at a certified endometriosis centre in Switzerland in 2022 were analysed retrospectively. …”
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21437
Erector spinae plane block versus transversus abdominis plane block with rectus sheath block for postoperative analgesia in laparoscopic hepatectomy: a randomized clinical trial
Published 2025-04-01“…This study aims to compare the efficacy of bilateral ultrasound-guided ESPB versus subcostal TAPB with RSB for postoperative analgesia, addressing the gap in current research and optimizing pain management strategies for this procedure. Methods Sixty patients scheduled for laparoscopic hepatectomy were randomly divided into two groups: E group received ultrasound-guided ESPB, while the TR group received subcostal TAPB with RSB. …”
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21438
Am I attached? A patient-partnered approach to creating infographics about attachment to primary care in Ontario, Canada
Published 2024-11-01“…Our approach to engaging patients prevented both oversimplification and unnecessary complexity in a public-facing visual about attachment to primary care.…”
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21439
The Effect of Polymorphisms in the CYP2D6 and CYP2C9 Genes on the Clinical Efficacy of Tramadol and Ketorolac When Using the Accelerated Recovery Protocol in Patients With Uncompli...
Published 2020-10-01“…Analgesic efficacy was assessed using a visual analog scale (VAS) and McGill Pain Questionnaire.Results. …”
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21440
Episode-specific cortical functional connectome reorganization and neurobiological correlates in bipolar disorder: a cross-sectional study
Published 2025-08-01“…The mBD showed expanded visual and prefrontal regions but compressed motor and precuneus regions. …”
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