Mean Arteriolar Diameter Measured from Wide-Field Swept-Source OCT Angiography: A Highly Sensitive Indicator for Mean Arterial Pressure by Yuchen Li, Yuyao Qu, Hanze Zhang, Yue Bian, Langxuan Yuan, Jingbo Hu, Shengrui Xu, Xiayu Xu, PhD, Jianqin Lei, MD

“…Eligible eyes had a corrected visual acuity of 20/25 or better and an intraocular pressure (IOP) not exceeding 21 mmHg. …”
Get full text

Predicting the risk of postoperative avascular necrosis in patients with talar fractures based on an interpretable machine learning model by Jian Zhang, Jian Zhang, Jian Zhang, Jihai Xu, Jihai Xu, Jiapei Yu, Jiapei Yu, Jiapei Yu, Hong Chen, Hong Chen, Xin Hong, Songou Zhang, Xin Wang, Xin Wang, Chengchun Shen, Chengchun Shen, Chengchun Shen

“…PurposeThis study aims to develop and validate an interpretable machine learning model for predicting avascular necrosis (AVN) following talar fracture, thereby aiding in personalized prevention and treatment.MethodsA retrospective cohort study included patients undergoing surgical intervention for talar fractures at Ningbo No.6 Hospital between January 2018 and December 2023. …”
Get full text

Optimizing Corticosteroid Sinonasal Irrigation Outcomes Through 3D Printing: A Randomized Pilot Clinical Trial by Zachary T. Root, Thomas J. Lepley, Kanghyun Kim, Aspen R. Schneller, Songzhu Zhao, Raymond Wen, Veronica L. Formanek, Sarah M. Sussman, Joseph S. Lee, Ahmad Odeh, Lai Wei, Kathleen M. Kelly, Bradley A. Otto, Kai Zhao

“…Patient‐reported outcome measures (Nasal Obstruction Symptom Evaluation, Sinonasal Outcome Test‐22, and Visual Analog Scale of nasal congestion) improved significantly among all groups. …”
Get full text

White matter hyperintensity tissue property spatial variations as a function of cognitive status in Parkinson’s disease by Mariyemuguli Reheman, Sagar Buch, Naying He, Pei Huang, Qiurong Yu, Xinhui Wang, Yu Liu, Youmin Zhang, Zhijia Jin, Yan Li, Peng Liu, Shengdi Chen, E. Mark Haacke, Fuhua Yan

“…Water content, T1, and T2* measures were derived from qMRI data and tissue property heatmaps and periventricular distance profiles were constructed for all groups to visualize location-dependent tissue alterations of WMH relative to the lateral ventricles. …”
Get full text

Photothermal‐Responsive Soluble Microneedle Patches for Meibomian Gland Dysfunction Therapy by Fei Yu, Xuan Zhao, Qian Wang, Yifei Niu, Peng Xiao, Jinze Zhang, Keyi Fei, Yuancong Huang, Liu Liu, Po‐Han Fang, Xinyue Du, Weihua Li, Dalian He, Tingting Zhang, Saiqun Li, Jin Yuan

Get full text

Machine learning discrimination of Gleason scores below GG3 and above GG4 for HSPC patients diagnosis by Bingyu Zhu, Longguo Dai, Huijian Wang, Kun Zhang, Chongjian Zhang, Yang Wang, Feiyu Yin, Ji Li, Enfa Ning, Qilin Wang, Libo Yang, Hong Yang, Ruiqian Li, Jun Li, Chen Hu, Hongyi Wu, Haiyang Jiang, Yu Bai

“…Among the ensemble learning methods, RF, XGBoost, and Adaboost performed the best. …”
Get full text

Effects of Varying Text Message Length and Driving Speed on the Disruptive Effects of Texting on Driving Simulator Performance: Differential Effects on Eye Glance Measures by Rimzim Taneja, Kawther Alali, Mohammed, Ki-Jana Malone, Brandon Buchanon, Ashley Blanchette, Dung Ho, Doreen Head, Randall Commissaris

“…Eye glances off the roadway are a measure of the visual distraction associated with texting while driving. …”
Get full text

Factors influencing the course of post-COVID-19-related symptoms: A bidirectional cohort study among employees in health and welfare services in Germany by Steinke, Lara, Peters, Claudia, Nienhaus, Albert, Bethge, Matthias, Koch, Peter

“…Objective: The aim of this study was to determine the prevalence and trajectory of persistent symptoms following COVID-19 and to investigate factors influencing these among employees in the health and welfare services in Germany.Methods: This exploratory, mixed retro- and prospective cohort study using paper-and-pencil questionnaires was conducted among insured persons of the German Social Accident Insurance Institution for the health and welfare services with a SARS-CoV-2 infection in 2020. …”
Get full text

Comparison of Cemented Bipolar Hemiarthroplasty versus Proximal Femoral Nail Antirotation in Patients with Unstable Intertrochanteric Femur Fractures: A Prospective Interventional... by Aditya Kumar Singh, Akshat Mittal, Manvendra Singh Rawat, Sanjay Dalakoti, Anil Kumar Joshi, Pavneesh Kumar Lohan, Chandra Shekhar, Indrajit Das Bhoumik

“…Outcomes assessed included Harris Hip Score (HHS), pain using the Visual Analogue Scale (VAS), operative time, blood loss, time to weight-bearing, hospital stay and complications. …”
Get full text

Assessing the Use of BotulinumtoxinA for Hyperactive Urinary Tract Dysfunction a Decade After Approval: General Versus Local Anesthesia for BotulinumtoxinA Detrusor Injection by Heinrich Schulte-Baukloh, Apostolos Apostolidis, Catarina Weiss, Thorsten Schlomm, Sarah Weinberger, Dirk Höppner, Kathrin Haberecht, Carsten Waskow, Hendrik Borgmann, Jörg Neymeyer, Bernhard Ralla

“…We examined the level of anxiety and pain experienced by patients who wanted to have the procedure performed under LA or general anesthesia (GA). <b>Material and Methods</b>: Patients scheduled for OnabotA DI were able to choose the anesthesia procedure (LA or GA). …”
Get full text

Clinical characteristics and surgical treatment comparison of multisegmental spinal tuberculosis: a retrospective analysis by Zongqiang Yang, Zongqiang Yang, Zhangui Gu, Zhangui Gu, Qiang Liu, Qiang Liu, Long Ma, Le Fei, Le Fei, Ningkui Niu, Ningkui Niu, Jiandang Shi

“…BackgroundTo analyze the therapeutic efficacy of intervertebral surgery in the treatment of multisegmental spinal tuberculosis (MSTB) by evaluating its clinical outcomes and perioperative indicators, thereby providing evidence-based insights to optimize surgical strategies and improve clinical decision-making.MethodsThis retrospective cohort study analyzed 134 MSTB patients treated at our hospital between January 2000 and June 2022. …”
Get full text

Prediction of solid pseudopapillary tumor invasiveness of the pancreas based on multiphase contrast-enhanced CT radiomics nomogram by Dabin Ren, Liqiu Liu, Aiyun Sun, Yuguo Wei, Tingfan Wu, Yongtao Wang, Xiaxia He, Zishan Liu, Jie Zhu, Guoyu Wang

“…A radiomics nomogram was subsequently constructed and visualized by combining traditional CT independent predictors and radiomics signature. …”
Get full text

Effect of Traditional Chinese Medicine collapse stains combined with western medicine in treating acute herpes zoster (中药溻渍联合西医治疗急性期带状疱疹的疗效观察)... by YAO Meiyu (姚美玉), SUN Mingli (孙明丽), TANG Ling (唐玲), ZHOU Jie (周洁), CHEN Hong (陈宏)

“…The pain degree measured by Visual Analogue Scale (VAS) and treatment efficacy of the two groups were compared. …”
Get full text

Prevalence of falls and associations with family functioning among community-dwelling older adults in Guangzhou, China by Si-Yu Sun, Zhi-Wei Wang, Zhi-Li Peng, Le-Xin Yuan, Wen-Hao Yang, Wen-Jian Zhang, Jia-Min Chen, Wei-Quan Lin, Wei Zhu, Wei Zhu

“…Consequently, this study aims to investigate the prevalence and influencing factors of falls among community-dwelling older adults in Guangzhou, China, with a particular emphasis on the impact of family functioning.MethodsWe used a multi-stage stratified cluster random sampling technique to successfully survey 2,399 individuals aged 65 and above across 11 districts in Guangzhou City. …”
Get full text

Efficacy of topical Raphanus sativus seed powder mixed with honey versus hydroquinone 4 % cream in the treatment of melasma – A randomized controlled trial by Arshan Horti, Shaikh Nisar Ahmed Abbas, Shavana Fathima, Mamadapur Saba Abdul Razzaq, Arsheya Parvez Mistry, Farooqui Shazia Parveen, Nazim Husain

“…Secondary measures examined subjective nuances using a 100 mm visual analogue scale (VAS) and recorded the dermatology life quality index (DLQI) at baseline and the conclusion of the study. …”
Get full text

Biomechanical and clinical differences in muscle tone, stiffness, range of motion, and pain perception in children with cerebral palsy: a cross-sectional study by Ramón González-Matilla, Ramón González-Matilla, Ramón González-Matilla, Vanesa Abuín-Porras, Isabel Mínguez-Esteban, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo, Alberto M. Heredia-Rizo

“…ROM was assessed by goniometry, and pain perception was evaluated using the Visual Analog Scale during a Straight Leg Raise (SLR) test. …”
Get full text

Rheumatoid arthritis and psoriatic arthritis: is the disease impact different? A large matching study at diagnosis and after 1 year of treatment by Annette H M van der Helm-van Mil, Pascal H P de Jong, Sytske Anne Bergstra, Elise van Mulligen, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Maikel van Oosterhout, Jos H van der Kaap, Selinde V J Snoeck Henkemans, Anne-Fleur van den Biggelaar

“…Therefore, we aimed to determine the difference in disease impact between matched RA and PsA patients at diagnosis and after 1 year in two different regions.Methods RA patients from the treatment in the Rotterdam Early Arthritis CoHort trial (tREACH), PsA patients from the Dutch southwest Early PsA cohoRt (DEPAR) and RA and PsA patients from the Leiden Early Arthritis Clinic (EAC) were included. …”
Get full text

Efficacy and safety of photobiomodulation combined with oral cryotherapy on oral mucosa pain in patients with burning mouth syndrome: a multi-institutional, randomized, controlled... by Chenghui Lu, Xuan Zhou, Chenglong Yang, Xinxiang Jiang, Xin Li, Zefan Huang, Qing Du, Guoyao Tang

“…The coprimary outcome measures were changes in visual analogue scale (VAS) scores and the overall response rate between baseline and 7 weeks of treatment. …”
Get full text

The effect of supplementation with type I and type III collagen peptide and type II hydrolyzed collagen on pain, quality of life and physical function in patients with meniscopathy... by Ahmet Serhat Genç, Ali Kerim Yılmaz, Berna Anıl, Esra Korkmaz Salkılıç, Enes Akdemir, Berna Güzel, Ahmet Mor, Hacı Ahmet Yarar, Nizamettin Güzel, Lokman Kehribar

“…This study aimed to evaluate the effects of Naturagen® 4 Joint product containing type I, II, and III collagen on pain, quality of life, and physical functions in patients with meniscopathy. Methods This randomized, double-blind, placebo-controlled clinical study included 32 patients (collagen = 17 and placebo = 15) with meniscopathy. …”
Get full text

NETs activate the GAS6-AXL-NLRP3 axis in macrophages to drive morphine tolerance by Qingyan Tian, Haiyue Guo, Mengyao Zhang, Kunmao Jiang, Fan Hu, Yan Xu, Li Wan, Xiaokai Zhou, Yinbing Pan, Wentao Liu, Chun-Yi Jiang

“…Confocal laser scanning microscopy was utilized to visualize NETs in the dorsal root ganglion (DRG) and in cells. …”
Get full text