¿Los pacientes octogenarios sometidos a reemplazo total de rodilla regresan a la actividad física? by J. Teves, F. Holc, A. García-Mansilla, S. Vildoza, R. Brandariz, L. Carbó, J. Costantini

“…The objective is evaluate the pre and postoperative physical activity measured with the Knee Society Score (KSS) score and the Tegner score. Materials and methods: A retrospective cohort analysis was conducted on patients who underwent total knee replacement (TKR) between January 2016 and December 2019 at our institution. …”
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[Translated article] Do octogenarian patients undergoing total knee replacement return to physical activity? by J. Teves, F. Holc, A. García-Mansilla, S. Vildoza, R. Brandariz, L. Carbó, J. Costantini

“…The objective is evaluate the pre and postoperative physical activity measured with the Knee Society Score (KSS) score and the Tegner score. Materials and methods: A retrospective cohort analysis was conducted on patients who underwent total knee replacement (TKR) between January 2016 and December 2019 at our institution. …”
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Combining patient-reported outcome measures to screen for active disease in rheumatoid arthritis and psoriatic arthritis by Annette H M van der Helm-van Mil, Pascal H P de Jong, Paco M J Welsing, Ilja Tchetverikov, Jolanda J Luime, Marijn Vis, Marc R Kok, Paul Baudoin, Lindy-Anne Korswagen, Selinde V J Snoeck Henkemans, Agnes E M Looijen, Gonul Hazal Koc

“…Objectives To investigate whether a combination of general health (Visual Analogue Scale (VAS)), Health Assessment Questionnaire-Disability Index (HAQ-DI), pain (VAS/Numerical Rating Scale (NRS)), quality of life (EQ-5D), fatigue (VAS/NRS) and presenteeism (0%–100% productivity loss) could aid as a screening tool to detect active disease in patients with rheumatoid arthritis (RA) and psoriatic arthritis (PsA).Methods RA patients from the tREACH trial and TARA trial (n=683) and PsA patients from the DEPAR cohort (n=525) were included. …”
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Increased Risk of Central Serous Chorioretinopathy among Patients with Nonorganic Sleep Disturbance by Peng-Tai Tien, Chien-Yu Lai, Chun-Ju Lin, Wen-Lu Chen, Po-Kang Lin, Chih-Hsin Muo, Yi-Yu Tsai, Lei Wan, Wen-Chao Ho, Hui-Ju Lin

“…Patients with central serous chorioretinopathy (CSC) typically present with acute visual impairment and metamorphopsia. The disease previously has been associated with psychological stress. …”
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Systemizing and Transforming Preterm Oral Feeding Through Innovative Algorithms by Rena Rosenthal, Jean Chow, Erin Sundseth Ross, Rudaina Banihani, Natalie Antonacci, Karli Gavendo, Elizabeth Asztalos

“…These resources included detailed instructions, visual aids, and step-by-step guides to help staff understand and apply the algorithms effectively. …”
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An Effective and Safe Laser Treatment Strategy of Fractional Carbon Dioxide Laser for Chinese Populations with Periorbital Wrinkles: A Randomized Split-Face Trial by Xianglei Wu, Qingqing Cen, Jian Jin, Wei Gao, Ying Shang, Linting Huang, Xiaoxi Lin

“…We aimed to explore the optimum energy and coverage parameters of CO2 AFL for treating static periorbital wrinkles in a Chinese population and to minimize PIH incidence. Methods In total, 30 patients with static periorbital wrinkles were recruited. …”
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Development and temporal external validation of a novel nomogram for predicting one-year mortality in the older adult with hip fracture by Yangfan Gong, Kai Zhang, Wei Chen, Qiqi Yang, Mingyue Shi, Zhao Dong, Zhuohao Yin, Yuyu Zhang, Wei Ge

“…ObjectiveThe aim of this study was to develop a novel nomogram for predicting one-year mortality in the older adult patients with hip fracture and to further evaluate its effectiveness.MethodsThis retrospective cohort research analyzed the clinical data of 1,263 older adult patients with hip fractures who underwent surgery at the First Affiliated Hospital of Air Force Military Medical University from January 2014 to December 2022. …”
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Epigenetic modifications are associated with mRNA and cytokine expression changes in chronic rhinosinusitis: a multiomics study from the United States by Devyani Lal, Tripti Brar, Chantal McCabe, Erik Jessen, Nitish Kumar, Pedro Lança Gomes, Michael J. Marino, Amar Miglani, Hirohito Kita

“…We therefore performed a multi-omics study integrating epigenetic (DNA methylation), transcriptomic (mRNA), and proteomic (cytokine) data of CRS sinonasal tissue to visualize interactions amongst these modalities to study our hypothesis.MethodsSinonasal tissue was collected from 14 prospectively enrolled CRS and control subjects. …”
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Aspartate aminotransferase-to-platelet ratio index as a novel predictor of early mortality in heat stroke patients: a multi-centre retrospective study by Min Wang, Yun Li, Yuan Cao, Meng-Meng Yang, Fu-Jing Liu, Jie Jiao, Sheng-Yuan Wang, Bin Song, Lu Wang, Yi-Qi Wu, Hong-Jun Kang

“…Restricted cubic splines (RCS) were utilized to visualize the relationship between APRI and 28-day mortality risk. …”
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Effect of Traditional Chinese Medicine ointment rubbing therapy in the treatment of primary dysmenorrheal (中药膏摩治疗原发性痛经疗效观察) by CAO Lei (曹蕾), ZHANG Lijun (张丽君), KONG Xiaochun (孔晓春), CHEN Hong (陈宏)

“…The pain degree was evaluated by Visual Analogue Scale (VAS), and the effect of intervention was compared between two groups. …”
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AlphaMissense Predictions and ClinVar Annotations: A Deep Learning Approach to Uveal Melanoma by David J. Taylor Gonzalez, MD, Mak B. Djulbegovic, MD, MSc, Meghan Sharma, MD, MPH, Michael Antonietti, BS, Colin K. Kim, BS, Vladimir N. Uversky, PhD, DSc, Carol L. Karp, MD, Carol L. Shields, MD, Matthew W. Wilson, MD

“…Subjects: Genetic data from patients diagnosed with UM were analyzed, explicitly focusing on missense mutations sourced from the Catalogue of Somatic Mutations in Cancer (COSMIC) database. Methods: We identified missense mutations frequently observed in UM using the COSMIC database, assessed their potential pathogenicity using AlphaMissense, and visualized mutations using AlphaFold. …”
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Pediatric endoscopic retrograde pancreatography expertise in chronic pancreatitis: a single-center analysis by Hongxi Guo, Juan Luo, Hu Yang, Jun Yang, Hongqiang Bian, Xufei Duan, Xin Wang

“…Postoperative pancreatitis developed in 2 cases (5.9%, 2/34), and hyperamylasemia occurred in 5 cases (14.7%, 5/34). The postprocedure visual analogue scale (VAS) score for abdominal pain significantly decreased from 6 to 1 (P < 0.001). …”
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Outcomes of Bilateral Scandinavian Total Ankle Replacement: A Detailed Analysis of Implant Survivability and Patient-Reported Outcomes by Alexandra Hunter Aitchison BS, Albert T. Anastasio MD, Kevin A. Wu BS, Emily Poehlein MB, Cynthia Green PhD, Samuel B. Adams MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD

“…This study aimed to evaluate the survivability and patient-reported outcomes of simultaneous bilateral STAR, focusing on implant survival rates and improvements in quality of life, function, and pain relief. Methods: A retrospective cohort study was conducted on all patients managed with primary TAR performed simultaneously with bilateral STAR prostheses at our institution from July 1998 to February 2008. …”
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Comparative efficacy of the modified minimally invasive “Parachute Technique” vs. the intermuscular GAP Approach in proximal humeral fracture management: a prospective study by Jia Jia Wei, Jia Jia Wei, Jun Li, Tao Chen, Hong Chi Yi, Wen Tao Zhao, Tian Tian, Jian Wei Wang

“…This study compares the Modified Minimally Invasive Parachute Technique and the Intermuscular Gap Approach in the management of displaced PHFs.ObjectiveTo compare clinical outcomes, including surgical efficiency, complication rates, functional recovery, and radiographic healing, between the two surgical techniques.MethodsA total of 40 patients aged 60 or older with displaced two- or three-part PHFs were randomized into two groups (n = 20 per group). …”
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Identification of subgroups of early-stage mycosis fungoides patients with increased itch and impaired quality of life by Julia Nenonen, Anna H. Winther, Anna H. Winther, Pontus Jonsson, Pontus Jonsson, Lina U. Ivert, Lina U. Ivert, Hanna Brauner, Hanna Brauner

“…This single center study investigated associations between QoL/itch/depressive symptoms and clinical phenotypes in patients with CTCL with particular focus on early MF-stages.MethodsPatients were included during routine dermatological care. …”
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Hyperreflective focuses as a biomarker of multiple sclerosis progression by A. Zh. Fursova, M. Y. Zubkova, M. A. Vasilyeva, Y. A. Gamza, A. S. Derbeneva, I. F. Nikulich, N. A. Malkova, A. I. Prokaeva, P. N. Pozdnyakova

“…Purpose: to identify the intraretinal hyperreflective foci (HRF), their specific characteristics, localization features and correlations with the duration of the disease, type of course and previous episodes of optic neuritis (ON) in multiple sclerosis (MS) patients using a high-resolution OCT scanning protocol. Materials and methods. The study included 160 patients (318 eyes) divided into 8 groups, i.e. …”
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Feasibility and safety of transvaginal natural orifice transluminal endoscopic surgery (V-NOTES) panhysterectomy: a polycentric retrospective study by Panlian Qian, Weimin Chen, Bin Su, Yao Chen, Wulin Shan, Huimin Tang, Weiwei Wei, Huihui Wang, Bairong Xia, Jiming Chen

“…The operation duration, intraoperative blood loss, postoperative exsufflation time, postoperative activity time, hospital stay, treatment cost, 6 h activities of daily living (ADL) score after the operation, cosmetic score, visual analog score, and complications were observed in the two groups. …”
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Outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries: a single-center study by Shengwen Xiang, Zhen Hu, Zihao Ren, Guangqing Cai, Zhijiang Ao, Weiguo Hu, Yangbo Liu, Xing Li, Licheng Wei

“…Abstract Objective To evaluate the outcomes of arthroscopic one-stage repair and reconstruction of Schenck II–IV knee dislocations with multiple ligament injuries. Methods We retrospectively reviewed the data of patients with Schenck II–IV knee dislocations and multiple ligament injuries treated in our hospital during 2019–2022. …”
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The influence of type 2 diabetes mellitus on clinical manifestations of osteoarthritis by E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, E. P. Sharapova, N. M. Savushkina, K. M. Mikhailov, T. A. Raskina, I. B. Vinogradova, E. N. Otteva, E. V. Zonova, O. N. Anoshenkova, A. M. Lila

“…Objective: to investigate in a multicenter study relationship between type 2 diabetes mellitus (DM) and clinical manifestations of osteoarthritis (OA). Material and methods. The study involved 767 patients aged 40–75 years with a confirmed diagnosis of stage I–III knee OA who had signed an informed consent form. …”
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The dose-dependent efficacy of esketamine in spinal surgery with intraoperative neuroelectrophysiological monitoring: a randomized controlled trial by Chunyan Lin, Chunyan Lin, Jianlin Wang, Long Zhang, Long Zhang, Liyong Yuan, Guanyi Liu, Guanyi Liu, Miao Zhu, Liangguang Zhang

“…PurposeThis study aims to validate the efficacy and safety of combining different doses of esketamine with propofol, remifentanil, and dexmedetomidine in spinal surgery under intra-operative neuroelectrophysiological monitoring (IONM).MethodsAll enrolled patients underwent a total intravenous anesthesia (TIVA) maintenance regimen, which included propofol, remifentanil, and dexmedetomidine. …”
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