Deep learning based on multiparametric MRI predicts early recurrence in hepatocellular carcinoma patients with solitary tumors ≤5 cm by Tingting Mu, Xinde Zheng, Danjun Song, Jiejun Chen, Xuewang Yue, Wentao Wang, Shengxiang Rao

“…Purpose: To evaluate the effectiveness of a constructed deep learning model in predicting early recurrence after surgery in hepatocellular carcinoma (HCC) patients with solitary tumors ≤5 cm. Materials and methods: Our study included a total of 331 HCC patients who underwent curative resection, with all patients having preoperative dynamic contrast-enhanced MRI (DCE-MRI). …”
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Reconceptualizing Pediatric Strabismus as a Condition Rooted in Sensory Processing Disorder: A Novel Case-Based Hypothesis by Mirjana Bjeloš, Ana Ćurić, Mladen Bušić, Katja Rončević, Adrian Elabjer

“…<b>Background/Objectives:</b> A direct link between sensory processing disorder (SPD) and strabismus has not been systematically investigated, though prior studies suggest sensory modulation may influence visual behaviors. Traditional approaches view strabismus through a binary lens—either normal or pathological motor deviation. …”
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Short-term clinical and functional outcomes of distal biceps tendon fixation: all-suture vs. titanium anchors by Felix Hochberger, MD, Julian Hess, MD, Christian Konrads, MD, Tizian Heinz, MD, Ella Segatz, Maximilian Rudert, MD, Kilian List, MD

“…Background: The objective of this study was to evaluate the preliminary clinical and functional outcomes of patients with distal biceps tendon ruptures undergoing surgical fixation using 2 intramedullary all-suture anchors (ASAs) and to compare these outcomes with a control group treated with 2 intramedullary titanium anchors (TAs). Methods: A retrospective case series was conducted on patients who underwent distal biceps tendon fixation using either TAs (Mitek Sports Medicine, Raynham, MA, USA) or ASAs (Arthrex, Naples, FL, USA). …”
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Comparative analysis of stentless aortic root and composite valve grafts for aortic root replacement: a retrospective single-centre study by Maria Comanici, Mohammad Yousuf Salmasi, Fabio De Robertis, Toufan Bahrami, Sunil K. Bhudia, Jullien A. Gaer, Shahzad G. Raja

“…This study aims to analyze the in-hospital outcomes and long-term survival of these two surgical approaches. Methods: A retrospective analysis was conducted on 594 patients who underwent ARR between July 2003 and December 2023. …”
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Modified minimally invasive surgical technique plus Bio-Oss Collagen for regenerative therapy of isolated interdental intrabony defects: study protocol for a randomised controlled... by Ye Han, Churen Zhang, Haidong Zhang, Zhaoguo Yue, Lili Miao, Kaining Liu, Jianxia Hou

“…This study will search for differences between M-MIST combined with Bio-Oss Collagen, and M-MIST alone in regeneration therapy for intrabony defects.Methods and analysis The present research is designed as a two-group parallel randomised controlled trial. …”
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Transanal Irrigation in Patients with Low Anterior Resection Syndrome After Rectal-Sphincter-Preserving Surgery for Oncological and Non-Oncological Disease: A Systematic Review by Andrea Morini, Massimiliano Fabozzi, Magda Zanelli, Francesca Sanguedolce, Andrea Palicelli, Alfredo Annicchiarico, Candida Bonelli, Maurizio Zizzo

“…The aim of the present systematic review was to evaluate the feasibility and effectiveness of TAI in patients with significant LARS symptoms. Methods: We performed a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and guidelines in addition to the <i>Cochrane Handbook for Systematic Reviews of Interventions</i>. …”
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Resting-State Brain Network Characteristics Related to Mild Cognitive Impairment: A Preliminary fNIRS Proof-of-Concept Study by Guohui Yang, Chenyu Fan, Haozheng Li, Yu Tong, Shuang Lin, Yashuo Feng, Fengzhi Liu, Chunrong Bao, Hongyu Xie, Yi Wu

“…Background: This study investigates the reliability of functional near-infrared spectroscopy (fNIRS) in detecting resting-state brain network characteristics in patients with mild cognitive impairment (MCI), focusing on static resting-state functional connectivity (sRSFC) and dynamic resting-state functional connectivity (dRSFC) patterns in MCI patients and healthy controls (HCs) without cognitive impairment. Methods: A total of 89 MCI patients and 83 HCs were characterized using neuropsychological scales. …”
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The Impact of Prostate-Specific Antigen and Gleason Scores on Cardiovascular Death in Prostate Cancer Patients after Radiotherapy or Chemotherapy: A Population-Based Study by Huijuan He, Liyu Guo, Peipei Wang, Yuting Yang, Zhenxing Lu, Xiaoping Peng, Tianwang Guan

“…This study explored the association between PC tumor characteristics and CVD risk in PC patients who had received RT or CT. Methods: Fine-gray competitive risk analysis was employed to identify CVD risk factors. …”
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Alflutop Russian longitudinal multicenter observational study: use in patients with chronic back pain (message 3) by A. M. Lila, A. E. Karateev, L. I. Alexeeva, E. A. Taskina, An. B. Danilov, S. A. Zhivolupov, I. N. Samartsev, E. R. Barantsevich, A. P. Rachin

“…The use of slow-acting disease-modifying symptomatic drugs, such as bioactive concentrate from small marine fish (BCSMF, Alflutop), is considered a potential element of complex therapy for chronic non-specific back pain (CNBP).Objective: to evaluate the efficacy of the BCSMF in patients with CNBP in real-life clinical practice.Material and methods. An open observational study included 10,047 patients with CNBP (age – 58.3±14.9 years, 58.4% women) with moderate or severe pain – 60 [50; 70] mm on the visual analogue scale (VAS). …”
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Observation of the clinical effectiveness of transanal opening of the intersphincteric space in the treatment of high intersphincteric anal fistula and suprasphincteric anal fistul... by Huang Luqiao, Li Shanshan, Yang Yong, Meng Qingliang, Liang Chunhui, Pan Dong, Sun Shangying, Xie Guangwei, Zhang Zhengguo

“…[Objectives] To investigate the clinical effectiveness of transanal opening of the intersphincteric space (TROPIS) in the treatment of high intersphincteric anal fistula and suprasphincteric anal fistula. [Methods] A total of 124 patients with high intersphincteric anal fistula and suprasphincteric anal fistula who underwent surgical treatment at the Department of Anorectal Surgery, Xuzhou Central Hospital from September 2021 to June 2023 were selected as the study subjects. …”
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PHARMACOEPIDEMIOLOGY OF ORIGINAL DROTAVERINE USE IN DYSMENORRHEA: RESULTS OF AN INTERNATIONAL MULTICENTER STUDY by A. L. Unanyan, V. A. Alimov, S. E. Arakelov, M. S. Afanasyev, D. V. Baburin, D. V. Blinov, T. D. Guriyev, U. V. Zimovina, A. E. Kadyrova, Yu. M. Kossovich, L. S. Polonskaya

“…Pain was evaluated asking patients to rate the worst abdominal pain over the past 12 hours (11-point Numerical Pain Rating Scale, NPRS) and a Visual Analogue Scale (VAS) to evaluate the drotaverine onset of action. …”
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Based on Network Pharmacology Tools to Investigate the Molecular Mechanism of Cordyceps sinensis on the Treatment of Diabetic Nephropathy by Yan Li, Lei Wang, Bojun Xu, Liangbin Zhao, Li Li, Keyang Xu, Anqi Tang, Shasha Zhou, Lu Song, Xiao Zhang, Huakui Zhan

“…This study is aimed at revealing the therapeutic mechanisms of Cordyceps in DN by undertaking a network pharmacology analysis. Materials and Methods. In this study, active ingredients and associated target proteins of Cordyceps sinensis were obtained via Traditional Chinese Medicine Systems Pharmacology Database (TCMSP) and Swiss Target Prediction platform, then reconfirmed by using PubChem databases. …”
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Correlations between symptoms, nasal endoscopy and computed tomography findings in patients with chronic rhinosinusitis without nasal polyps by Savović Slobodan, Dragnić Nataša, Kljajić Vladimir, Jovančević Ljiljana, Buljčik-Čupić Maja, Lemajić-Komazec Slobodanka

“…The aim of this paper was to determine if there is a correlation between the symptoms, nasal endoscopy and CT in patients with CRSsNP. Methods. The study included 110 patients with CRSsNP. …”
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NUCLEAR MEDICINE IMAGING IN THE DETECTION OF LOCALLY ADVANCED LARYNGEAL AND HYPOPHARYNGEAL CANCER by A. A. Medvedeva, V. I. Chernov, R. V. Zeltchan, I. G. Sinilkin, I. G. Frolova, S. V. Chizevskaya, E. L. Choynzonov, O. V. Cheremisina, A. V. Goldberg

“…The 99mTc-MIBI uptake in metastatic lymph nodes was visualized in 2 (17 %) of the 12 patients. 28 SLNs were detected by SPECT and 31 SLNs were identifed using the intraoperative gamma probe. …”
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Effect of Laser Photobiomodulation on Postoperative Pain After Single-Visit Endodontic Treatment in Children: A Randomized Control Trial by Yashaswini S. Angolkar, Sadanand Kulkarni, Chandrashekar M. Yavagal, Puja C. Yavagal, Umesh Bhosle, Viplavi Chavan Patil, Sultan Abdulrahman Almalki, Inderjit Murugendrappa Gowdar, Khalid Gufran

“…Pain scores were measured using a 10-point Visual Analog Scale (VAS) at 4, 12, 24, and 48 h post-treatment. …”
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Oral donor site evaluation in the early and late postoperative periods for augmentation and replacement urethroplasty by M. M. Iritsyan, A. A. Klimenko, A. A. Mantsov, I.-N. K. Suyundikov, A. P. But, R. A. Rakhmatov, M. V. Prismakova, E. M. Alekberov, S. V. Kotov

“…To evaluate early and late postoperative changes in the donor area after oral graft extraction for urethroplastyMaterials &amp; methods. A retrospective analysis of the results of surgical treatment using oral mucosa from 2017 to 2022 was carried out. …”
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Language function improvement and cortical activity alteration using scalp acupuncture coupled with speech-language training in post-stroke aphasia: A randomised controlled study by Bingbing Lin, Jinglei Ni, Xiao Xiong, Lanlan Zhang, Jian Song, Mengxue Wang, Linsong Chai, Yunshi Huang, Jia Huang

“…Our objectives were to evaluate the impact of scalp acupuncture on the cerebral cortex of post-stroke aphasia patients. Methods: This assessor-blinded, parallel-arm design, single-center, randomized clinical trial recruited 64 patients with post-stroke aphasia. …”
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Generating synthetic brain PET images of synaptic density based on MR T1 images using deep learning by Xinyuan Zheng, Patrick Worhunsky, Qiong Liu, Xueqi Guo, Xiongchao Chen, Heng Sun, Jiazhen Zhang, Takuya Toyonaga, Adam P. Mecca, Ryan S. O’Dell, Christopher H. van Dyck, Gustavo A. Angarita, Kelly Cosgrove, Deepak D’Souza, David Matuskey, Irina Esterlis, Richard E. Carson, Rajiv Radhakrishnan, Chi Liu

“…We therefore aim to generate synthetic [11C]UCB-J PET images based on MRI in this study. Methods We implemented a convolution-based 3D encoder-decoder to predict [11C]UCB-J SV2A PET images. …”
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Health-related quality of life with bemarituzumab plus mFOLFOX6 in patients with FGFR2b-overexpressing, advanced gastric or gastroesophageal junction cancer by Z.A. Wainberg, P.C. Enzinger, S. Qin, K. Yamaguchi, J. Wang, X. Zhou, A. Gnanasakthy, K. Taylor, A. Yusuf, I. Majer, A. Jamotte, Y.-K. Kang

“…Using data from the final analysis, we analyzed patient-reported outcomes (PROs) to evaluate the impact of adding bemarituzumab to mFOLFOX6 on health-related quality of life (HRQoL). Materials and methods: Patients were randomized 1 : 1 to bemarituzumab plus mFOLFOX6 (n = 77) or placebo plus mFOLFOX (n = 78). …”
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Functional Recovery After Hip Arthroplasty with a Minimal Invasive or Classical Approach Eight Years After Intervention by Mirela Vuckovic, Lana Ruzic, Karlo Tudor, Tomislav Prpic, Zdravko Jotanovic, Silvije Segulja, Andrica Lekic, Ksenija Bazdaric

“…<b>Background:</b> The aim of this study was to investigate differences in functional recovery eight years after total hip arthroplasty in patients who underwent hip joint surgery using two different approaches: the classic lateral approach and the anterolateral minimally invasive surgical approach. <b>Methods:</b> Eight years after the hip replacement, 68 subjects, 32 in the classic and 36 in the minimally invasive group, underwent follow-up measurements involving the Harris Hip Score (HHS), range of motion, strength of the abductor muscles, 50-m walk time, body mass index (BMI), physical activity questionnaire, and visual analogue scale (VAS) pain during general activities. …”
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