Discrepancies in Peripheral Arterial Function Indices Among Healthy Young Black Africans: Findings from Pilot Study Interpreted Using AHA Reference Values by Tuntufyege Erasto Mwasanjobe, Ashabilan Ebrahim, Oscar Mbembela, Omary Chillo, Jacktan Josephat Ruhighira, Fredirick Mashili

“…The results were also analyzed across sex and between the left and right sides. Methods We carefully and systematically recruited 156 healthy black Africans aged 18–35 years with no characteristics indicative of peripheral arterial dysfunction. …”
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The impact of pituitary adenomas on cognitive performance: a systematic review by Ting-Chia Young, Kai-Yen Lin, Wan-Cheng Li, Chi-Ning Huang, Wen-Hsuan Tsai

“…PurposeIncreasing evidence suggests that beyond classical endocrine and visual symptoms, patients with pituitary adenoma (PA) may experience neurocognitive impairment, potentially resulting in reduced productivity and diminished quality of life. …”
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A Complete Functional Characterization of Patients with Severe Knee Osteoarthritis in Need of Total Knee Replacement by Vinicius Taboni Lisboa, Bruno de Paula Leite Arruda, Rafael de Andrade Tambascia, Alessandro Rozin Zorzi, Alberto Cliquet, Gustavo Constantino de Campos

“…The main outcome measures were Western Ontario and McMaster Universities Index (WOMAC), visual analog scale (VAS), Short Form-36, knee range of motion, thigh perimeter measurement, maximum voluntary isometric contraction, and 6-min walk test. …”
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Understanding Patient and Physiotherapist Requirements for a Personalized Automated Smartphone Telemonitored App for Posttotal Knee Arthroplasty Rehabilitation: Qualitative Study by Eleanor Shuxian Chew, Aileen Eugenia Scully, Samanth Shi-Man Koh, Ee-Lin Woon, Juanita Krysten Miao-Shi Low, Yu-Heng Kwan, John Wei-Ming Tan, Yong-Hao Pua, Celia Ia-Choo Tan, Luke Jonathan Haseler

“…To ensure uptake and long-term sustainability, this study adopted a person-based approach. MethodsA multistakeholder qualitative study of user needs was conducted. …”
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The relationship of tooth shade and skin tone and its influence on smile attractiveness in native South Indians: A web-based cross sectional survey by Hrudi Sundar Sahoo, Aishwarya Balasubramanian

“…These images were incorporated into a Google Form along with a questionnaire and a Visual Analog Scale (VAS) for attractiveness rating. …”
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Tracing inflammasomes in Alzheimer’s: insights from bibliometric analysis by Yingjun Chen, Yingjun Chen, Hui Pei, Hao Li, Wenjun Zeng, Zhitao Li

“…By identifying research hotspots and emerging topics, we aim to provide new insights and directions for researchers in this field.MethodsAll data related to inflammasomes in Alzheimer’s disease from 2000 to 2024 were collected from the Web of Science Core Collection (WoSCC), and annual publications, national publication trends, and proportion charts were analyzed and plotted using GraphPad price v8.0.2. …”
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Patient Experience with ABBV-444, a Proof-of-Concept Study for a Novel Artificial Tear with Trehalose and Sodium Hyaluronate for Dry Eye Symptoms by Hom MM, Ladhani O, Zhang Z, Liu H, Sonparote S, Dancey CC

“…We assessed symptom relief, tolerability, and patient experience of a novel carboxymethyl-cellulose–based artificial tear formulation with trehalose and sodium hyaluronate (ABBV-444) in patients with DED.Methods: This open-label, single-arm, single center study enrolled adult patients with baseline Ocular Surface Disease Index (OSDI) scores of ≥ 18 and ≤ 65. …”
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The burden of cough in idiopathic pulmonary fibrosis and other interstitial lung diseases: a systematic evidence synthesis by Rhiannon Green, Michael Baldwin, Nick Pooley, Kate Misso, Maureen PMH Rutten-van Mölken, Nina Patel, Marlies S. Wijsenbeek

“…To inform future research, treatment and care models, we conducted the first systematic synthesis of evidence on its associated burden. Methods A literature search was performed for articles published between January 2010 and October 2023 using databases including Embase, MEDLINE and the Cochrane Library. …”
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Effect of golimumab on endothelial vasomotor function and arterial stiffness in ankylosing spondylitis by L. A. Knyazeva, N. Damjanov, L. I. Knyazeva, N. S. Meshcherina, I. I. Goryainov, M. A. Stepchenko, Ya. I. Bobyntsev, O. S. Rudakov

“…Objective: to evaluate the effect of golimumab (GLM) on endothelial vasomotor function and arterial stiffness in patients with ankylosing spondylitis (AS).Subjects and methods. A total of 42 patients with advanced-stage AS, who were older than 18 years and met the 1984 modified New York criteria with a disease duration of ≤5 years, were examined. …”
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Unravelling the pathogenic role and genotype-phenotype correlation of the USH2A p.(Cys759Phe) variant among Spanish families. by Raquel Pérez-Carro, Fiona Blanco-Kelly, Lilián Galbis-Martínez, Gema García-García, Elena Aller, Blanca García-Sandoval, Pablo Mínguez, Marta Corton, Ignacio Mahíllo-Fernández, Inmaculada Martín-Mérida, Almudena Avila-Fernández, José M Millán, Carmen Ayuso

“…(Cys759Phe) allele.<h4>Materials and methods</h4>Diagnosis was set according to previously reported protocols. …”
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Effects of Remimazolam-Propofol with Flumazenil Reversal on the Emergence Time and Hemodynamics of Patients Undergoing Laparoscopic Partial Hepatectomy: A Prospective Randomized Co... by Feng Y, Jia JM, Cheng YX, Lin J, Zhang XY, Wang YZ, Zuo YB

“…Whether remimazolam and propofol combined with flumazenil reversal can accelerate the recovery and enhance hemodynamic stability remains controversial.Methods: Fifty patients aged 18– 70 years with American Society of Anesthesiologists (ASA) class I–III and Child-Pugh classification A or B undergoing elective laparoscopic partial hepatectomy were enrolled. …”
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Endoscopic signs of gastroesophageal reflux disease with different hiatal hernias types by A. O. Nykonenko, Ye. I. Haidarzhi, О. М. Kiosov

“…The proximal edges of the gastric folds, which are visualized in all patients, were considered the reference point for the true esophageal-gastric junction. …”
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18F−Prostate−Specific Membrane Antigen PET/CT imaging for potentially resectable pancreatic cancer (PANSCAN−2): a phase I/II study by Jisce R. Puik, Thomas T. Poels, Gerrit K. J. Hooijer, Matthijs C. F. Cysouw, Joanne Verheij, Johanna W. Wilmink, Elisa Giovannetti, Geert Kazemier, Arantza Farina Sarasqueta, Daniela E. Oprea-Lager, Rutger-Jan Swijnenburg

“…This phase I/II study aimed to assess the feasibility of 18F-PSMA PET/CT to detect PDAC. Methods Seventeen patients with clinically resectable PDAC underwent 18F-PSMA PET/CT prior to surgical resection. …”
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An explainable AI-driven deep neural network for accurate breast cancer detection from histopathological and ultrasound images by Md. Romzan Alom, Fahmid Al Farid, Muhammad Aminur Rahaman, Anichur Rahman, Tanoy Debnath, Abu Saleh Musa Miah, Sarina Mansor

“…This research introduces the Deep Neural Breast Cancer Detection (DNBCD) model, an explainable AI-based framework that utilizes deep learning methods for classifying breast cancer using histopathological and ultrasound images. …”
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Immediate Analgesic Efficacy of Acupuncture in Acute Postoperative Pain Following Internal Fixation of Intertrochanteric Femoral Fractures: Protocol for a Randomized Controlled Tri... by Wang H, Wang T, Tang X, Tang X, Li C, Deng Y, Li Q, Liang F, Liao J, Guo T

“…The primary outcome will be pain intensity measured by the Visual Analogue Scale (VAS) at 10 minutes post-treatment. …”
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A novel infrapatellar fat pad preservation technique in anterior cruciate ligament reconstruction reduces postoperative pain and cartilage damage: a retrospective study by Shilin Li, Mingfeng Lu, Lilian Zhao, Lilei He, Weifeng Fan, Jie Zhou, Sumin Yan

“…Comparative assessments included the Kujala score, International Knee Documentation Committee (IKDC) score, KT-1000 arthrometer measurements, visual analogue scale (VAS) score, and range of motion (ROM). …”
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Additive Therapeutic Effects of Topical Sirolimus Following Oral Propranolol Therapy for Kaposiform Hemangioendothelioma by Xiu B, Xu Z, Xu Z, Zhang B, Wei L, Ma L

“…Efficacy was assessed by Visual Analog Scale (VAS), Doppler ultrasound, and a four-grade evaluation system; safety was monitored throughout.Results: All patients showed significant improvement within 6– 12 months (mean: 9.6 months), achieving Grade III or IV response. …”
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A bibliometric analysis of studies related to the nuclear factor kappa B signaling pathway in knee osteoarthritis between 2004 and 2023 by Yafeng Mo, Jiahao Chu, Tiewu Chen, Wenbing Liu, Jing Tang

“…ObjectiveThis study aimed to identify the principal research areas and trends in the nuclear factor kappa B (NF-κB) signaling pathway in knee osteoarthritis (KOA).MethodsThe Web of Science core collection (WoSCC) database was searched for studies related to the NF-κB signaling pathway in KOA published between 2004 and 2023. …”
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Holiday Weight Change in a US College Student Sample: A Prospective Observational Cohort Study by Hannah B. Yoo, Casen Bigham, Tanisha Basu, Sharmin Akter, Tiffany Tsai, Alexis Brown, Sara Kiros, Shruthi Durai, Claire Brown, Martin Binks

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An Analysis of the Vocational-Educational Problematics for Substantiating Production Specialist Competencies by V. E. Steinberg, L. V. Vakhidova, E. M. Gabitova

“…The methodology was designed for the differentiation, specification and justification of relevant specialised competencies, which complement universal and general professional competencies documented in educational standards.Methodology and research methods. As a research methodology, a causal approach was used, specifically implemented in the form of a multi-dimensional matrix informing a stage-by-stage analysis, which links the need for qualified personnel (experts, who have necessary competencies) with the pedagogical conditions for their preparation (formation of necessary competencies in students).Results and scientific novelty. …”
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