Comparative evaluation of antimicrobial peptides: effect on formation, metabolic activity and viability of Klebsiella pneumoniae biofilms by Sophia Hanstein, Thomas Grochow, Marina Mötzing, Marina Mötzing, Simone A. Fietz, Ralf Hoffmann, Ralf Hoffmann, Christoph G. Baums, Sophie Kähl

“…The objective of this study was to comparatively evaluate the effect of selected AMPs on the formation, metabolic activity and viability of Klebsiella pneumoniae biofilms of veterinary and human origin.MethodsBiofilm formation of three K. pneumoniae strains was quantified using the crystal violet assay and visualized by scanning electron microscopy (SEM). …”
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Effects of Self-Assisted Manual Therapy Combined with a High-Intensity Walking Program on Musculoskeletal Pain, Functionality, and Posture in Older Adults: A Multicentre Randomized... by Gemma Victoria Espí-López, Laura Fuentes-Aparicio, Rocío Cogollos-de-la-Peña, Lucas Monzani, Elena Marques-Sule, Dagmar Pavlu, Anna Arnal-Gómez

“…This study aims to analyse the effect of a combined protocol of self-assisted manual therapy and high-intensity walking on musculoskeletal back pain, functionality, and shoulder posture in older adults, and to establish the short- and medium-term effects of this program. Methods: A multicentre, double-blind, randomized trial was conducted on older adults. …”
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InP/ZnS core/shell quantum dots: Synthesis, characterization and their application in fullerene derivative based flexible solar cells by Chen Zhichu, Muhammad Tahir, Fida Muhammad, Fakhra Aziz, Ambreen Ayub, Fazal Badshah, Moamen S. Refat, Sadiye M. Cakmak, Shanza Rehan, Abdel Majid A. Adam, Amnah Mohammed Alsuhaibani, Afida Ayob, Mahidur R Sarker, Adam Khan

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Artificial Intelligence‐Based Detection of Central Retinal Artery Occlusion Within 4.5 Hours on Standard Fundus Photographs by Ayse Gungor, Ilias Sarbout, Aubrey L. Gilbert, Steffen Hamann, Pierre Lebranchu, Cristina Hobeanu, Philippe Gohier, Catherine Vignal‐Clermont, Oana M. Dumitrascu, Salomon‐Yves Cohen, Wolf A. Lagrèze, Nicolas Feltgen, Frank van der Heide, Cédric Lamirel, Jost B. Jonas, Michael Obadia, Daniel Racoceanu, Dan Milea

“…Methods Our retrospective, cross‐sectional study included 1322 color fundus photographs from 771 patients with acute visual loss due to CRAO, central retinal vein occlusion, nonarteritic anterior ischemic optic neuropathy, and healthy controls. …”
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Machine learning discrimination of Gleason scores below GG3 and above GG4 for HSPC patients diagnosis by Bingyu Zhu, Longguo Dai, Huijian Wang, Kun Zhang, Chongjian Zhang, Yang Wang, Feiyu Yin, Ji Li, Enfa Ning, Qilin Wang, Libo Yang, Hong Yang, Ruiqian Li, Jun Li, Chen Hu, Hongyi Wu, Haiyang Jiang, Yu Bai

“…Among the ensemble learning methods, RF, XGBoost, and Adaboost performed the best. …”
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OCT Angiography Analysis of Retinal and Choroidal Flow after Proton Beam Therapy for Choroidal Melanoma by Su-Kyung Jung, MD, Edward H. Lee, MD, Kavita K. Mishra, MD, Inder K. Daftari, PhD, Susanna S. Park, MD, PhD

“…Methods: After a comprehensive eye examination, including BCVA, Optovue AngioVue was used to obtain the 4.5-mm optic disc and 6.0-mm macular OCT/OCT angiography (OCTA) images of both eyes. …”
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Efficacy and safety of intravitreal anti-VEGF for myopic choroidal neovascularization by Jing-Yao Liu, Ju-Ping Liu, Xiao-Rong Li

“…AIM: To report the 24mo outcomes of vascular endothelial growth factor (VEGF) inhibitors for myopic choroidal neovascularization (mCNV) in routine clinical practice and simultaneously evaluated the real-world safety. METHODS: The patients who received intravitreal injections of VEGF inhibitors of either ranibizumab (0.5 mg) or conbercept (0.5 mg) for mCNV were analyzed from 1 January 2017 to 1 January 2022. …”
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Efficacy of aerobic exercises for knee osteoarthritis: a network meta analysis of randomized clinical trials by Yuan Luo, Xiao Chen, Haibo Gong, Li Chen, Liyue Zhang, Shuqiang Li

“…To address this knowledge gap, we performed a systematic network meta-analysis to compare and rank the clinical efficacy of various aerobic exercise regimens for managing KOA. Methods A systematic literature search was conducted across five electronic databases (PubMed, Cochrane Library, Web of Science, Embase, and Scopus) from database inception through June 2024. …”
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Brain temperature, brain metabolites, and immune system phenotypes in temporal lobe epilepsy by Christina Mueller, Huixian Hong, Ayushe A. Sharma, Hongwei Qin, Etty N. Benveniste, Jerzy P. Szaflarski

“…Methods Thirty‐six (36) participants, 18 with temporal lobe epilepsy (13 females) and 18 age‐matched healthy controls (nine females), were enrolled prospectively and underwent MRSI/MRSI‐t; TLE participants also provided blood samples. …”
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Perceived Risks, Mitigation Strategies, and Modifiability of Telehealth in Rural and Remote Emergency Departments: Qualitative Exploration Study by Christina Tsou, Justin Yeung, Melanie Goode, Josephine Mcdonnell, Aled Williams, Stephen Colin Andrew, Jenny Tetlow, Andrew Jamieson, Delia Hendrie, Christopher Reid, Sandra Thompson

“…Objective This study explores the perceptions of ETS clinicians regarding acceptability, appropriateness, and clinical decision-making when delivering emergency telemedicine in rural and remote settings. MethodsThis qualitative study used semistructured interviews to explore the perspectives of ETS clinicians regarding the factors influencing their clinical decision-making. …”
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Return to yoga following anatomic or reverse total shoulder arthroplasty by Tammy R. Hoffman, BS, Lisa A. Galasso, MD, Matthew B. Noble, DO, Javier Ardebol, MD, MBA, Patrick J. Denard, MD

“…Additionally, any differences between anatomic total shoulder arthroplasty (aTSA) and reverse total shoulder arthroplasty (rTSA) were investigated. Methods: A retrospective study was performed on patients who underwent primary aTSA or rTSA between 2012 and 2022. …”
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Cerebral microbleeds: prevalence and relationship to clinical features in cognitive impairment with lewy body disease by Zhihong Ren, Jinghuan Gan, Zhichao Chen, Zhihong Shi, Shuai Liu, Hao Lu, Guili Zhang, Yong Ji

“…Thus, we investigated the clinical prevalence of CMBs and its relationship to clinical features in patients with DLB, PDD, mild cognitive impairment with Lewy bodies (MCI-LB) and Parkinson’s disease with MCI (PD-MCI) in this study. Methods In this retrospective multicenter cohort study, the study population consisted of 486 patients with DLB, 262 cases with PDD, 74 cases with MCI-LB and 107 cases with PD-MCI from 22 memory clinics between January 2018 and June 2022 in China. …”
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Faricimab Outcomes in Chorioretinal Disorders: Indian Real-World Analysis (FOCUS Study) by Agrawal V, Gupta A, Agrawal V, Sheth JU

“…Virendra Laser Phaco Surgery Centre, Jaipur, Rajasthan, India; 3Department of Retina Services, Shantilal Shanghvi Eye Institute, Mumbai, IndiaCorrespondence: Jay Umed Sheth, Department of Retina Services, Shantilal Shanghvi Eye Institute, CS No: 3/207, 4/207, RJ Gaikwad Road, Barkat Ali Dargah Road, Wadala East, Mumbai, 400037, India, Tel +91-9961167200, Email drjay009@gmail.comPurpose: To assess the real-world efficacy and safety of intravitreal faricimab in treating Diabetic Macular Edema (DME), neovascular Age-related Macular Degeneration (nAMD), and Central Macular Edema (CME) secondary to retinal vein occlusion (RVO) in an Indian population.Patients and Methods: This single‑center, retrospective observational study reviewed the records of 49 patients (49 eyes) diagnosed with DME, nAMD, or cystoid macular edema secondary to RVO, who received a total of 150 intravitreal faricimab injections and were followed for at least 24 weeks. …”
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A cross-sectional analysis of fall risk among institutionalized older adults in Malaysia by Zahira Zohari, Azliza Rahim, Hazwan Mat Din, Nurfaizah Saibul, Asiah Jafri, Shafikah Rahim, Faizah Nasir, Hakimah Mohammad Sallehuddin

“…Objective: To identify the fall risk factors among older adults in institutional care and evaluate their relationships with overall fall risk. Methods: This retrospective cross-sectional study analyzed data from 184 residents of a public institutional care home in Selangor, Malaysia. …”
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Bleb Morphology Using Anterior-Segment Optical Coherence Tomography after Ahmed Glaucoma Valve Surgery with Tenon Capsule Resection by Faried M. Wagdy

“…To evaluate the internal morphology of blebs using anterior-segment optical coherence tomography (AS-OCT) and the surgical outcomes of Ahmed glaucoma valve (AGV) surgery with Tenon capsule resection compared to conventional AGV surgery in patients with refractory glaucoma. Patients and Methods. This randomised prospective study included 30 eyes from 30 patients (age range: 42–55 y) with refractory glaucoma from March 2018 to February 2020. …”
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Multicentre assessment of transperineal targeted prostate biopsy performed as part of a targeted and systematic biopsy diagnostic strategy in men without previous prostate biopsies by Mohammed Sheweita, Liam Blaney, Jon Oxley, Douglas Kopcke, Stefanos Bolomytis, Paul Burn, Adrian Andreou, Jon Heron, Raj Persad, Nick Burns‐Cox, Jonathan Aning, the South West Prostate Dashboard collaborative

“…Patients and methods The outcomes of 2611 biopsy naïve men with MRI Score≥3 who underwent visual registration combined targeted and systematic LATPB at 5 hospitals between 2021 and 2024 were studied. …”
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Cataract Surgery Results after Penetrating Keratoplasty by M. A. Tanash, M. A. Frolov, V. Kumar, L. T. Ababneh, A. A. Alqudah

“…To compare clinical and refractive outcomes of cataract surgery by phacoemulsification and by extracapsular cataract extraction with implantation of foldable and rigid intraocular lenses in patients previously having undergone penetrating keratoplasty (PK).Patients and methods. This is a retrospective study. Medical records of all patients admitted for cataract surgery between 2010 and 2018 to the King Abdullah University Hospital (KAUH) were reviewed and medical records of patients who underwent cataract surgery after PK were analyzed. …”
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Myopic choroidal neovascularization with dilated choroid vessels is prone to progression into subretinal fibrosis following anti-vascular endothelial growth factor therapy: a retro... by Xiangjun She, Qiwei Cai, Wangjing Yao, Shixin Zhao, Zhe Lv, Suyan Shan, Jiwei Tao, Yun Zhang

“…Abstract Background This retrospective study aimed to identify risk factors for subretinal fibrosis (SF) and evaluate the response to anti-vascular endothelial growth factor (anti-VEGF) therapy in patients with myopic choroidal neovascularization (mCNV), with a specific focus on the role of dilated choroidal vessels (DCVs) in disease progression. Methods In this retrospective study, patients with high myopia (spherical equivalent < −6.0 D, pathological myopia, Asian ethnicity) and active mCNV lesions, diagnosed between 2021 to 2023, were evaluated. …”
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Obese Patients Demonstrate Higher Failure Rates, Infection Rates, and Inferior Patient-Reported Outcomes Compared With Nonobese Patients Following Multiligamentous Knee Surgery by Adam V. Daniel, M.D., Warren A. Williams, M.D., Brendan J. Kosko, M.D., Joshua A. Cohen, Andrew D. Carbone, M.D., Stanley J. Kupiszewski, M.D.

“…Purpose: To examine outcomes following surgically treated multiligamentous knee injuries (MLKIs) in obese versus nonobese patients. Methods: Patients who were surgically treated for MLKIs between 2008 and 2021 were included in this study. …”
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A web-based prediction model for brain metastasis in non-small cell lung cancer patients by Jianing Chen, Li Wang, Li Liu, Qi Wang, Jing Zhao, Xin Yu, Shiji Zhang, Chunxia Su

“…Accurate prediction of BM occurrence is essential for effective disease prevention and control during patient management. Methods Clinical characteristics from a cohort of 39,930 non-small cell lung cancer (NSCLC) patients were meticulously collected. 12 candidate variables were screened out through Least absolute shrinkage and selection operator (LASSO) regression analysis. …”
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