Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain by Christina Stevens, Elizabeth Kawecki-Wright, Avery Rowlison de Ortiz, Andrea Thomson, Savannah Aker, Erin Perry, Emily Haupt, Alejandra Mondino, Masataka Enomoto, Margaret E. Gruen, Margaret E. Gruen, B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles, B. Duncan X. Lascelles

“…This study aimed to use FLM to investigate the effect of various factors on physical activity patterns in a cohort of dogs with OA pain.MethodsNinety-nine client-owned dogs with radiographic and clinical evidence of OA were fitted with a collar-based activity monitor (Actigraph GT3X). …”
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Free-breathing, non-contrast, three-dimensional whole-heart coronary magnetic resonance imaging for the identification of culprit and vulnerable atherosclerotic plaque by Reza Hajhosseiny, Adam Hartley, Graham Cole, Camilla Munoz, Amarjit Sethi, Rasha Al-Lamee, Saud Khawaja, Sameer Zaman, James Howard, Deepa Gopalan, Ben Ariff, Raffi Kaprielian, Radhouene Neji, Karl P. Kunze, Amit Kaura, Claudia Prieto, Ramzi Khamis, René M. Botnar

“…Objectives: To validate iT2prep-BOOST in patients with non-ST-segment elevation myocardial infarction (NSTEMI). Methods: 41 patients with suspected NSTEMI were recruited. …”
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Evaluating Dental Pain in Diverse Conditions: Findings From Short-Form McGill Pain Questionnaire Study by Jin Wang, Yin-Fei Pu, Hong-Tao Chen, Xiang-Song Bai, Xue Yang, Ai-Ping Ji, Jie Bai

“…In this study, we compared the characteristics of dental pain in patients with different conditions using a Short-Form McGill Pain Questionnaire (SF-MPQ). Methods: A total of 1541 patients admitted to the Peking University School of Stomatology between February 2022 and July 2023 were assessed. …”
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Feasibility of relaxation along a fictitious field in the 2nd rotating frame (TRAFF2) mapping in the human myocardium at 3 T by Joao Tourais, Joao Tourais, Joao Tourais, Maša Božić-Iven, Maša Božić-Iven, Maša Božić-Iven, Yidong Zhao, Qian Tao, Iain Pierce, Iain Pierce, Christian Nitsche, Christian Nitsche, George D. Thornton, George D. Thornton, Lothar R. Schad, Lothar R. Schad, Thomas A. Treibel, Thomas A. Treibel, Sebastian Weingärtner, Mehmet Akçakaya, Mehmet Akçakaya

“…PurposeEvaluate the feasibility of quantification of Relaxation Along a Fictitious Field in the 2nd rotating frame (RAFF2) relaxation times in the human myocardium at 3 T.MethodsTRAFF2 mapping was performed using a breath-held ECG-gated acquisition of five images: one without preparation, three preceded by RAFF2 trains of varying duration, and one preceded by a saturation prepulse. …”
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Onset of End-Stage Atrophic Age-Related Macular Degeneration as an End Point—A Delphi Study: Classification of Atrophy Meetings Report 7 by Zhichao Wu, BAppSc(Optom), PhD, Srinivas R. Sadda, MD, Thomas Ach, MD, Barbara A. Blodi, MD, Ferdinando Bottoni, MD, Usha Chakravarthy, MD, PhD, Emily Y. Chew, MD, Christine A. Curcio, PhD, Frederick L. Ferris, III, MD, Monika Fleckenstein, MD, K. Bailey Freund, MD, Juan E. Grunwald, MD, Frank G. Holz, MD, Glenn J. Jaffe, MD, Sandra Liakopoulos, MD, Tock Han Lim, FRCSEd, Jordi M. Monés, MD, PhD, Sergio Pagliarini, MD, FRCOphth, Daniel Pauleikhoff, MD, Maximilian Pfau, MD, Philip J. Rosenfeld, MD, PhD, David Sarraf, MD, Steffen Schmitz-Valckenberg, MD, Richard F. Spaide, MD, Janet R. Sparrow, PhD, Giovanni Staurenghi, MD, Adnan Tufail, MD, Francesco Viola, MD, Robyn H. Guymer, MBBS, PhD

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The Knee-SCHOOL: a brief patient-centered multidisciplinary educational program for knee osteoarthritis by Denise Vianna Machado Ayres, Sabrina Saemy Tome Uchiyama, Andréa Oliveira Prates, Rosana Aparecida Freitas Lopes, Antenor Bispo Santos Silva, Denise Rodrigues Tsukimoto, Rosimeire Alves Amorim, Taynah Souza Ribeiro, Artur Cesar Aquino Santos, André Tadeu Sugawara, André Tadeu Sugawara, Marcos Montagnini, Linamara Rizzo Battistella, Linamara Rizzo Battistella, Marta Imamura, Marta Imamura

“…BackgroundKnee osteoarthritis (KOA) is the most common form of arthritis in adults and a leading cause of years lived with disability, representing a significant burden on healthcare worldwide.ObjectiveDescribe the structure and educational elements of the Knee-SCHOOL, a brief patient-centered multidisciplinary educational program for patients with KOA.DesignObservational prospective study.SettingAcademically affiliated rehabilitation outpatient center in Brazil.MethodsThe program consisted of three in-person educational sessions (4.5 hr each) for 55 community dwelling adults, aged ≥50 years, with primary KOA-related pain. …”
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MODULATION AS A MULTIMODAL TRANSLATION STRATEGY OF GRAPHIC NOVEL PERSEPOLIS BY M. SATRAPI by Anna V. Khodorenko

“…The methodology, therefore, combines a qualitative approach with methods of observation, description, and comparison, alongside elements of multimodal discourse analysis. …”
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Multimodal imaging analysis and structure-function correlation in patients exposed to pentosan polysulfate sodium by Sandra Hoyek, Eleni Konstantinou, Francesco Romano, Darren Chen, Celine Chaaya, Magdalena G. Krzystolik, Daniel Hu, Rachel Huckfeldt, Demetrios G. Vavvas, Leo A. Kim, Jason Lee, Elise De, John B. Miller, Nimesh A. Patel

“…Design: A cross-sectional consecutive case series. Methods: Patients exposed to PPS with and without maculopathy underwent color fundus photographs (CFP), optical coherence tomography (OCT), fundus autofluorescence (FAF; Spectralis OCT2, Heidelberg Engineering), macular swept-source OCT angiography (SS-OCTA; PLEX® Elite 9000, Carl Zeiss Meditec) using 3 × 3, 6 × 6, and 12 × 12-mm protocols, microperimetry (MAIA, CenterVue), and 10–2 Humphrey visual field. …”
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Neuropsychic manifestations in the Kyrgyz cohort of patients with systemic lupus erythematosus by G. M. Koylubaeva, T. M. Reshetnyak, E. A. Aseeva, K. S. Solovyov, A. S. Dzhumagulova, N. P. Tkachenko, E. R. Karimovа, A. Zh. Zhumakadyrova, E. Zh. Dzhishambaev, K. A. Dzhailobayeva, E. L. Nasonov

“…The aim of the investigation was to study neuropsychic manifestations (NPM) of systemic lupus erythematosus (SLE) in the Kyrgyz cohort of patients. Material and methods. The prospective study included 460 patients with a reliable diagnosis of SLE, verified according to the diagnostic criteria ACR (1997) and SLICC (2012), observed in the clinic of the Academician M. …”
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The median Effective Dose (ED50) and the 95% Effective Dose (ED95) of alfentanil in inhibiting responses to cervical dilation when combined with ciprofol during hysteroscopic proce... by Run Gao, Shu-Xi Li, Yan-Hong Zhou, Li Xing, Jin-Peng Fu, Jian-Jun Shen, Xin-Zhong Chen, Li-Li Xu

“…The requirement of ciprofol, the emergence time, the visual analogue scale score of pain at five time points, and the incidence of adverse events were recorded. …”
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Cross-sectional study of the perceived wellbeing of children in palliative care by Daniel Toro-Pérez, Ester Camprodon-Rosanas, Catalina Bolancé, Montserrat Guillen, Sergi Navarro Vilarrubí, Joaquin T. Limonero

“…Objective: To describe the perceived wellbeing (pWB) and the psychological characteristics of young people with life-limiting and life-threatening conditions (LLTCs). Methods: We conducted a cross-sectional study in young people aged 8 years or older with collection of data on demographic and disease-related variables from the health records. …”
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Single-cell analysis reveals the loss of FABP4-positive proliferating valvular endothelial cells relates to functional mitral regurgitation by Xiaohu Wang, Mengxia Fu, Weiteng Wang, Songren Shu, Ningning Zhang, Ruojin Zhao, Xiao Chen, Xiumeng Hua, Xin Wang, Wei Feng, Xianqiang Wang, Jiangping Song

“…Therefore, we aimed to comprehensively examine the cellular and molecular components of mitral valves in patients with MR. Methods We conducted a single-cell RNA sequencing (scRNA-seq) analysis of mitral valve leaflets extracted from six patients who underwent heart transplantation. …”
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Clinical efficacy of Ni-Ti memory alloy four-corner arthrodesis concentrator in the treatment of scaphoid nonunion advanced collapse: a follow-up of over 10 years by Baochuang Qi, Minzheng Guo, Chen Meng, Teng Wang, Chuan Li, Yongqing Xu

“… Purpose: Exploring the therapeutic effects of Ni-Ti shape memory alloy four-corner arthrodesis concentrator (NT-FCAC) in treating scaphoid nonunion advanced collapse (SNAC) and providing a decade-long follow-up report. Materials and methods: Twenty-six patients with SNAC underwent scaphoidectomy, along with four-corner arthrodesis fusion involving the capitate, lunate, triquetrum, and hamate, using NT-MFCAC. …”
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Natural orifice transluminal endoscopic surgery in urology: The Chinese experience by Xiaofeng Zou, Guoxi Zhang, Tianpeng Xie, Yuanhu Yuan, Rihai Xiao, Gengqing Wu, Xiaoning Wang, Hui Xu, Folin Liu, Yuting Wu, Yunfeng Liao, Quanliang Liu, Yinghao Sun, Bo Yang, Linhui Wang, Chuanliang Xu, Xiaofeng Gao

“…Objective: To describe the Chinese experience of natural orifice transluminal endoscopic surgery (NOTES) in urology. Methods: From December 2008 to May 2017, 35 animal experiments and 305 clinical surgeries of NOTES or natural orifices specimen extractions (NOSE) were performed in China. …”
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The Potential Benefits of a Novel Food Supplement Based on Cannabis Sativa, Boswellia, and Fish Oil for Pain and Inflammation in Physical Activity: Unraveling the Role of Orexin-A... by Antonietta Messina, Antonietta Monda, Valentina Vassallo, Girolamo Di Maio, Rita Polito, Marco La Marra, Salvatore Allocca, Maria Casillo, Fiorenzo Moscatelli, Cristina Scavone, Francesco Taturi, Vincenzo Monda, Giovanni Messina, Chiara Schiraldi, Marcellino Monda

“…This study aimed to evaluate the effects of Flector Softgel FS Integratore, a multi-component food supplement, on joint pain, inflammatory markers, metabolic health, and orexin-A levels in physically active adults. Methods: In this randomized, controlled, low-intervention study, 25 adult participants (aged 30–60 years and amateur athletes engaging in at least 3 sessions/week of moderate physical activity) were assigned to either a treatment group (n = 15 received Flector Softgel FS for 14 days) or a placebo group (n = 10). …”
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Impact of postoperative depression and immune-inflammatory biomarkers on the prognosis of patients with esophageal cancer receiving minimally invasive esophagectomy: a retrospectiv... by Pei-xin Tan, Lin-xin Wu, Shuang Ma, Shi-jing Wei, Tai-hang Wang, Bing-chen Wang, Bing-bing Fu, Jia-shuo Yang, Qing Zhao, Qing Zhao, Li Sun, Yi Liu, Tao Yan

“…This study aimed to investigate the interrelationship between depression and prognosis in patients with EC, with a focus on immune-inflammatory biomarkers.MethodsThis single-center retrospective trial was conducted at the National Cancer Center/Cancer Hospital of the Chinese Academy of Medical Sciences. …”
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16 weeks of moderate intensity resistance exercise improves strength but is insufficient to alter brain structure in Gulf War Veterans with chronic musculoskeletal pain: a randomiz... by Stephanie M. Van Riper, Jacob V. Ninneman, Jacob V. Ninneman, Aaron J. Stegner, Aaron J. Stegner, Brady A. Riedner, Brady A. Riedner, Laura D. Ellingson, Ryan J. Dougherty, Patrick J. O’Connor, Gunnar A. Roberge, Gunnar A. Roberge, Andrew L. Alexander, Andrew L. Alexander, Andrew L. Alexander, Doug C. Dean, Doug C. Dean, Doug C. Dean, Jill N. Barnes, Dane B. Cook, Dane B. Cook

“…This study tested the effects of 16 weeks of resistance exercise training (RET) on gray matter (GM) volume and white matter (WM) microstructure in Gulf War Veterans (GWVs) with CMP compared to GWV waitlist controls (WLC).MethodsFifty-four GWVs were randomly assigned to 16 weeks of RET (n = 28) or WLC (n = 26). …”
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Development and external validation of a nomogram prediction model based on quantitative coronary angiography for predicting ischemic lesions: a multi-centre study by Shuai Yang, Shuai Yang, Shuang Leng, Shuang Leng, Zhouchi Wang, Jiang Ming Fam, Jiang Ming Fam, Adrian Fatt Hoe Low, Adrian Fatt Hoe Low, Ru-San Tan, Ru-San Tan, Ping Chai, Ping Chai, Lynette Teo, Lynette Teo, Chee Yang Chin, Chee Yang Chin, John C. Allen, Mark Yan-Yee Chan, Mark Yan-Yee Chan, Khung Keong Yeo, Khung Keong Yeo, Aaron Sung Lung Wong, Aaron Sung Lung Wong, Soo Teik Lim, Soo Teik Lim, Qinghua Wu, Liang Zhong, Liang Zhong, Liang Zhong

“…This study aimed to construct and validate a QCA-based prediction model, represented as a nomogram, for predicting ischemic lesions defined by invasive fractional flow reserve (FFR) ≤ 0.80.MethodsIn this multi-centre study, we enrolled 220 patients with 303 interrogated vessels who underwent FFR measurements during clinically indicated invasive coronary angiography. …”
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Adolescents and adults with FOXP1 syndrome show high rates of anxiety and externalizing behaviors but not psychiatric decompensation or skill loss by Tess Levy, Tess Levy, Hailey Silver, Hailey Silver, Renee Soufer, Renee Soufer, Audrey Rouhandeh, Audrey Rouhandeh, Audrey Rouhandeh, Alexander Kolevzon, Alexander Kolevzon, Alexander Kolevzon, Alexander Kolevzon, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Joseph D. Buxbaum, Paige M. Siper, Paige M. Siper, Paige M. Siper

“…To date, much of the literature focuses on childhood symptoms and little is known about the FOXP1 syndrome phenotype in adolescence or adulthood.MethodsA series of caregiver interviews and standardized questionnaires assessed psychiatric and behavioral features of 20 adolescents and adults with FOXP1 syndrome. …”
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Three-Dimensional-Printed Isoniazid Chewable Gels for On-Demand Latent Tuberculosis Treatment in Children by Amanda de O. E. Moreira, Lêda Maria S. Azevedo Neta, Márcia Pietroluongo, Ana Paula dos S. Matos, Beatriz B. Correa, Beatriz H. Ortiz, André da S. Guimarães, Marcio Nele, Carollyne M. Santos, Ana Elizabeth C. Fai, Maria Helena Gonçalves, Flávio M. Shimizu, Monique S. Dos Santos, Rosemberg B. Moure, Diogo D. Nascimento, André Luis de A. Guimarães, Saint Clair dos S. G. Junior, Alessandra L. Vicosa, Lucio M. Cabral

“…This study aims to develop innovative 3D-printed chewable gels containing INH for LTBI treatment. <b>Methods</b>: The gels were formulated using gelatin and carrageenan gum, sugar-free sweeteners, and flavoring. …”
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