Treatment of osteoarthritic knee with high tibial osteotomy and allogeneic human umbilical cord blood–derived mesenchymal stem cells combined with hyaluronate hydrogel composite by Bo Seung Bae, Jae Woong Jung, Gyeong Ok Jo, Seon Ae Kim, Eun Jeong Go, Mi-La Cho, Asode Ananthram Shetty, Seok Jung Kim

“…Therefore, this study aimed to assess cartilage regeneration following the implantation of allogeneic human umbilical cord blood–derived mesenchymal stem cells (hUCB-MSCs) with HTO. Methods In this case series, ten patients underwent hUCB-MSC implantation with HTO. …”
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Roxadustat attenuates brain injury in mice with heat stroke by regulating mitochondrial fission and fusion by 10.16016/j.2097-0927.202405009, HUANG Xueyan, SHEN Tingting

“… Objective To explore the protective effect and underlying mechanism of roxadustat (FG-4592), hypoxia-inducible factor-α (HIF-α) prolyl hydroxylase inhibitor, on brain injury caused by heat stroke (HS). Methods A total of 140 male C57BL/6J mice (6~8 weeks old, weighing 18~22 g) were subjected, and 40 of them were randomly divided into HS group, and low-, medium- and high-dose roxadustat groups (LD, MD and HD groups, 5, 10 and 20 mg/kg), with 10 mice in each group. …”
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Use of a multidimensional RAPID3 questionnaire to assess the achievement of remission and minimal disease activity in patients with early psoriatic arthritis treated according to T... by E. Yu. Loginova, T. V. Korotaeva, A. D. Koltakova

“…The possibilities of using the RAPID3 questionnaire in patients with early PsA (ePsA) with T2T strategy have not yet been studied.Objective: to investigate whether the multi-dimensional RAPID3 questionnaire may be used to assess the achievement of remission and MDA in ePsA patients with a T2T (Treat-to-target) strategySubjects and methods. The investigation enrolled 61 patients (29 men and 32 women) with ePsA meeting the 2006 CASPAR criteria; the mean age of the patients was 37±10.6 years; the duration of PsA and psoriasis was 11.3±10.2 and 75.4±80.9 months, respectively. …”
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Association of Estimated Glucose Disposal Rate With Risk of Abdominal Aortic Aneurysm: Evidence From a Large-Scale Prospective Cohort Study of the UK Biobank by Yuanwei Chen, Ting Zhou, Songyuan Luo, Jizhong Wang, Fan Yang, Yingqing Feng, Lixin Fang, Jianfang Luo

“…This study sought to investigate the association between the eGDR levels and the risk of AAA development. Methods: This prospective cohort study enrolled participants from the UK Biobank who had complete eGDR measurements and no pre-existing AAA at baseline (2006–2010). …”
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Effect of Traditional Chinese Medicine nursing on functional rehabilitation and postoperative complications in patients undergoing percutaneous transforaminal endoscopic surgery fo... by XU Li (徐丽)

“…Objective To evaluate the application of Traditional Chinese Medicine nursing on functional rehabilitation and postoperative complications in patients undergoing percutaneous transforaminal endoscopic technique for lumbar disc herniation (LDH). Methods Totally 84 LDH patients undergoing percutaneous transforaminal endoscopic surgery were randomly divided into the control group and observation group, with 42 cases in each group. …”
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ML Auditing and Reproducibility: Applying a Core Criteria Catalog to an Early Sepsis Onset Detection System by Markus Schwarz, Ludwig Christian Hinske, Ulrich Mansmann, Fady Albashiti

“…In this paper, we apply our catalog to an early sepsis onset detection system use case. Methods: The assessment of the ML algorithm behind the sepsis prediction system takes place in a kind of external audit. …”
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The influence of the interfacing angle between the pedicle screw and support rods on the clinical outcomes after posterior lumbar-sacral topping-off surgery: A retrospective clinic... by Mingzheng Zhao, Honghao Yang, Shixuan Guo, Fengqi Cheng, Yaoshen Zhang, Yong Hai, Yuzeng Liu

“…Methods This study is a monocentric retrospective observational study that included patients diagnosed with lumbosacral degenerative disease and underwent topping-off surgery. …”
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Treatment of Patients With Vertical Maxillary Excess: Orthognathic Surgery vs Strategic Implant® (Clinical Cases Report) by A. Ihde, A. Chakranarayan, O. Sipic, P. Soni, S. Ihde, Y. Vares

“…To demonstrate on the example of two clinical cases the effectiveness of differential (depending on patient’s age and dental status) treatment of vertical maxillary excess by means of orthognathic surgery and Strategic implantation®. Materials and methods. Two clinical cases of vertical maxillary excess are shown, one of which was treated with orthognathic surgery, and the other – with Strategic Implant® technology. …”
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Comparative analgesic efficacy of ultrasound-guided nerve blocks induced by three anesthetics with different duration of action in the treatment of resistant neuropathic pain in th... by Jovanikić Olivera, Anđelić Gordana, Lepić Milan, Mirković Dušica, Jovanović Bojan, Dragović Tamara, Pavličević Goran, Lepić Toplica

“…Complications, side effects, the execution time of procedure and the onset time of local anesthetic were also investigated. Methods. In this prospective, randomized and doubleblinded study, 108 patients (of which 53 were diagnosed with diabetes and 55 with radiculopathy) with the resistant and chronic peripheral neuropathic pain in the lower extremities were treated with a series of ultra-sound assisted peripheral nerve blocks. …”
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Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

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End-to-end deep fusion of hyperspectral imaging and computer vision techniques for rapid detection of wheat seed quality by Tingting Zhang, Jing Li, Jinpeng Tong, Yihu Song, Li Wang, Renye Wu, Xuan Wei, Yuanyuan Song, Rensen Zeng

“…These findings were further supported by external samples and visualizations. The proposed end-to-end decision fusion DCNN model simplifies the training process compared to traditional two-stage fusion methods. …”
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Midline 1 associated with Fas signaling enhances murine antigen-induced arthritis by Nina Lukač, Nina Lukač, Darja Flegar, Darja Flegar, Sara Priselac, Tomislav Kelava, Tomislav Kelava, Alan Šućur, Alan Šućur, Maša Filipović, Maša Filipović, Dino Šisl, Dino Šisl, Martina Fadljević, Igor Radanović, Vedran Katavić, Vedran Katavić, Nives Zimmermann, Danka Grčević, Danka Grčević, Nataša Kovačić, Nataša Kovačić

“…In our study, absence of Fas resulted in decreased accumulation of myeloid cells in affected joints.MethodsProportions of synovial hematopoietic cells were assessed by flow cytometry in wild-type and Fas −/− mice with antigen-induced arthritis. …”
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Applications of Human‐Centered Design to Food Is Medicine Interventions: The THRIVE Pilot Trial by Khadijat Adeleye, Kennedy McDaniel, Irma Iribe, Adeline Assani‐Uva, Janice Dugbartey, Aminata Sinyan, Bijaya Bhattarai, Samantha DeMarco, Tosin Tomiwa, Mojisola Olusola‐Bello, Chelsea Akubo, Faith E. Metlock, D’Janee Kyeremeh, Adrián McMahon, Maya Kramer‐Johansen, India Washington, Peiyu Chen, Christy Rodriguez, Mia Johnson, William Xiao, Samuel Gledhill, Samuel Yeboah‐Manson, Natania Kurien, Lydia Vassiliadi, Jennifer Freeman, Anna Maria Izquierdo‐Porrera, Lessly Palencia, Valerie K. Sullivan, Yvonne Commodore‐Mensah, Oluwabunmi Ogungbe

“…We aimed to co‐design the THRIVE program (Adaptive Personalized Dietitian Coaching and Messaging With Produce Prescriptions to Improve Healthy Dietary Behaviors) among Black and Hispanic adults with hypertension living in healthy food priority areas in Maryland. Methods Using social cognitive theory and the human‐centered design double‐diamond framework, 3 iterative co‐design sessions were conducted. …”
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Positive rate and influencing factors of adolescent idiopathic scoliosis among school children aged 9 to 18 years in Xiamen, China by Zhongrui Peng, Yuanchao Li, Hong Yang, Yanfang Jiang, Yuqing Li, Mengyang Gao, Yangjingling Hua, Guimei Liu, Manqi Zhou, Tianmu Chen, Huarong Hong, Lei Li

“…Abstract Objective The present study aimed to investigate the positive rate of adolescent idiopathic scoliosis (AIS) among school children in Xiamen, Fujian province, China, and evaluate its possible risk factors. Methods The study was a school-based, cross-sectional scoliosis screening program in Xiamen city. …”
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Daily activities change is linked to acute angle closure occurrence in COVID-19 co-infected patients by Xiaojie Wang, Aijun Tian, Shaodan Zhang, Bo Qu, Lijun Zhao, Xiaojing Pan, Peng Lu, Xinqi Chang, Lu Yang, Shaoping Ha, Jibing Wang, Jiangang Yang, Xiaohui Wang, Peng Yao, Yuxia Yang, Wenzong Zhou, Zhaoyi Wang, Juntao Zhang, Chuanqi Lin, Junhua Li, Yanhua Jiang, Zhongxia Cheng, Zhixiang Ding, Siying Xiong, Cong Ye, Houyu Zhao, Nathan Congdon, Yuanbo Liang

“…Abstract Objectives To analyze the influence of daily activity-related factors associated with COVID-19 infection on the occurrence of acute angle closure (AAC). Methods A multicenter hospital-based study was conducted at 23 ophthalmic centers in 17 provincial-level regions across China to recruit patients with confirmed AAC during the post-lockdown time of COVID-19 (P-TOC) from Dec 7, 2022, to Jan 17, 2023, and three lockdown time of COVID-19 (TOC) periods, which included the TOC-2022 (Sep 7, 2022 - Dec 6, 2022), TOC-2021(Sep 7, 2021 - Jan 6, 2022) and TOC-2020 (Sep 7, 2020 - Jan 6, 2021). …”
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Osteopenia Metabolomic Biomarkers for Early Warning of Osteoporosis by Jie Wang, Dandan Yan, Suna Wang, Aihua Zhao, Xuhong Hou, Xiaojiao Zheng, Jingyi Guo, Li Shen, Yuqian Bao, Wei Jia, Xiangtian Yu, Cheng Hu, Zhenlin Zhang

“…<b>Introduction</b>: This study aimed to capture the early metabolic changes before osteoporosis occurs and identify metabolomic biomarkers at the osteopenia stage for the early prevention of osteoporosis. <b>Materials and Methods</b>: Metabolomic data were generated from normal, osteopenia, and osteoporosis groups with 320 participants recruited from the Nicheng community in Shanghai. …”
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Changes in pain perception in women undergoing Breast Screening Mammograms: a Study based on Breast structure. by Deborah Esposito, Carmen Ludeno, Simona Marinelli, Anna Bertoldi, Valeria Selvestrel, Marianna Giannattasio, Lauretta Rizzari, Vincenzo Marra, Luisella Milanesio, Alfonso Frigerio, Andrea Luparia, Adriana Aiello, Livia Giordano, Emanuela Bovo, Elisa Camussi, Franca Artuso

“…Quality technical standards have been evaluated by two technical experts of Referring Regional Mammography Centers of Turin. MATERIALS AND METHODS Pain, in order to be detected, has been measured through the Visual Analogical Scale. …”
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Post Hoc Analysis of Anxiety and Behavioral Changes in Japanese Patients With Inflammatory Bowel Disease due to the COVID‐19 Pandemic: Relationship Between Municipal Population at... by Kohei Wagatsuma, Masanori Nojima, Takayuki Matsumoto, Minoru Matsuura, Hideki Iijima, Katsuyoshi Matsuoka, Naoki Ohmiya, Shunji Ishihara, Fumihito Hirai, Ken Takeuchi, Satoshi Tamura, Fukunori Kinjo, Nobuhiro Ueno, Makoto Naganuma, Kenji Watanabe, Rintaro Moroi, Nobuaki Nishimata, Satoshi Motoya, Koichi Kurahara, Sakuma Takahashi, Atsuo Maemoto, Hiroto Hiraga, Masayuki Saruta, Keiichi Tominaga, Takashi Hisabe, Hiroki Tanaka, Shuji Terai, Toshihiro Inokuchi, Hironobu Takedomi, Kazuyuki Narimatsu, Katsuya Endo, Masanao Nakamura, Tadakazu Hisamatsu, Hiroshi Nakase, J‐DESIRE Group

“…In this post hoc analysis of J‐DESIRE, we investigated the relationship between the municipal population size at the place of residence (MPSPR) and anxiety among patients with IBD in Japan during the COVID‐19 pandemic. Methods and Results We analyzed 2958 questionnaires collected from patients with IBD aged ≥ 16 years between March 2020 and June 2021. …”
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‘A good decision is the one that feels right for me’: Codesign with patients to inform theoretical underpinning of a decision aid website by Kelly Kohut, Kate Morton, Karen Hurley, Lesley Turner, The CanGene‐CanVar Patient Reference Panel, Caroline Dale, Susan Eastbrook, Rochelle Gold, Kate Henwood, Sonia Patton, Reshma Punjabi, Helen White, Charlene Young, Julie Young, Elizabeth Bancroft, Lily Barnett, Sarah Cable, Gaya Connolly, Beth Coad, Andrea Forman, Helen Hanson, Grace Kavanaugh, Katherine Sahan, Katie Snape, Bethany Torr, Rosalind Way, Elizabeth Winchester, Alice Youngs, The International Lynch Decision Aid Stakeholder Panel, Diana Eccles, Claire Foster

“…The aim of an innovative workshop described here was to engage with the people who will use the PtDA regarding the theoretical underpinning and logic model outlining our hypothesis of how the PtDA would lead to more informed decision‐making. Methods Short presentations about psychological and behavioural theories by an expert were interspersed with facilitated, small‐group discussions led by patients. …”
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Evaluation of the efficacy and safety of a combination of chondroitin sulfate and glucosamine sulfate for knee and hip osteoarthritis in real clinical practice by A. E. Karateev, Yu. V. Barysheva, Ya. V. Belokon, T. Yu. Bolshakova, Yu. Yu. Grabovetskaya, E. A. Dolzhenkova, L. N. Eliseeva, O. B. Ershova, E. V. Zonova, I. Yu. Chernova, A. O. Isakanova, M. N. Kirpikova, V. T. Komarov, E. V. Kryukova, A. I. Kulikov, D. I. Lakhin, L. A. Levasheva, L. V. Masneva, L. V. Menshikova, Yu. V. Mishina, S. V. Norina, Yu. N. Pashkovsky, A. V. Petrov, A. G. Rusanov, A. V. Sarapulova, K. A. Svodtseva, O. V. Semagina, A. N. Sudakova, S. N. Tkachenko, M. M. Toporkov, S. K. Tutelyan, G. R. Fadienko, O. S. Filonenko, O. P. Fomina, A. S. Chernov

“…The emergence of new drugs based on this combination substantially expands treatment options for OA therapy.Objective: to evaluate the efficacy and safety of Artroflex® that is a combination of chondroitin sulfate 400 mg and glucosamine sulfate 500 mg (CS + GS) to support joint health in patients with knee and/or hip OA.Patients and methods. When implementing an open observational research program, the results of using the CS + GS complex were assessed in 644 OA patients (74.7% women) (mean age, 58.0±14.6 years) who experienced moderate/severe pain and required to continuously take non-steroidal anti-inflammatory drugs (NSAIDs). …”
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