The first experience of using upadacitinib in the treatment of rheumatoid arthritis in real clinical practice (results of the multicenter project “RACURS”) by V. N. Amirjanova, A. E. Karateev, E. Y. Pogozheva, A. A. Baranov, V. I. Mazurov, R. R. Samigullina, O. N. Anoshenkova, N. A. Lapkina, T. Yu. Grineva, E. L. Nasonov, A. M. Lila

“…During the first week of taking the drug, there was a marked decrease in pain from 60 to 30 mm on a visual analogue scale, which lasted until the third month of therapy. …”
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Differential correlations of refractive error, axial length, and axial length-to-corneal curvature ratio with anterior segment biometrics in myopic refractive surgery candidates by Jian Zhang, Youlin Zhu, Ping Yuan, Xiaojuan Dong, Manyun Xie, Zongrui Ma, Rong Tian

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Age-related features of calcium pyrophosphate deposition disease by M. S. Eliseev, O. V. Zhelyabina, M. N. Chikina

“…The age-related features of the disease have not been studied.Objective: to study age-related features of CPPD.Subjects and methods. A total of 113 patients (54 men and 59 women) who had received inpatient or outpatient treatment at the V.A. …”
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Comparison of the effects of IMRT and IMPT on MRI features of normal brain tissue: a retrospective study by Jian Xu, Lili Zhang, Tingting Liu, Qingzeng Liu, Jian Zhu

“…And evaluate the potential application value of radiomic features in dose optimization and biological dose assessment. Methods A retrospective analysis included 113 patients undergoing brain-target radiotherapy: 44 receiving IMPT (average total dose: 5713.63 ± 774.32 cGy) and 69 receiving IMRT (average total dose: 5489.86 ± 627.05 cGy). …”
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The i‐gel® supraglottic airway device compared to endotracheal intubation as the initial prehospital advanced airway device: A natural experiment during the COVID‐19 pandemic by Daniel B. Levi, Joris Hoogendoorn, Shenae Samuels, Lindsay Maguire, Ruben Troncoso, Scott Gunn, Matthew Katz, Christine VanDillen, Susan A. Miller, Jay L. Falk, Steven H. Katz, Linda Papa

“…The objective was to compare first‐pass success and timing to successful airway placement between ETI and the i‐gel® SGA under extenuating circumstances. Methods This pre/post study compared airway placement metrics in prehospital patients requiring advance airway management for non‐trauma‐related conditions. …”
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Triple positivity for autoantibodies in patients with rheumatoid arthritis is associated with a severe course of the disease but not with bone turnover markers by Tomasz Budlewski, Joanna Sarnik, Olga Brzezinska, Anna Lewandowska-Polak, Tomasz Poplawski, Joanna Samanta Makowska

“…This study aimed to evaluate the correlation between autoantibody profiles, disease activity, bone turnover markers, and selected SNPs in a cohort of Polish RA patients. Material and methods A total of 138 RA patients from the Department of Rheumatology, Medical University of Lodz, were enrolled. …”
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Evaluating the Efficacy and Safety of 48-Week Low-Dose Dienogest Administration in Patients With Dysmenorrhea Caused by Endometriosis: Protocol for a Randomized, Open-Label, Parall... by Kyoko Kikuno, Ryuta Asada, Takuma Ishihara, Yoshimasa Bomoto, Saki Murase, Yoko Ueda, Tomomi Shiga, Yoh Hayasaki, Tatsuro Furui, Satoko Matsuzaki, Masahiko Takemura, Kazutoshi Matsunami, Makoto Kubo, Naoki Ito, Masanori Isobe, Ken-ichirou Morishige

“…The primary endpoint is the change in the pain visual analog scale (VAS) score from baseline to 48 weeks. …”
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Patient-specific computational flow simulation reveals significant differences in paravisceral aortic hemodynamics between fenestrated and branched endovascular aneurysm repair by Kenneth Tran, MD, Celine Deslarzes-Dubuis, MD, Sebastien DeGlise, MD, Adrien Kaladji, MD, Weiguang Yang, PhD, Alison L. Marsden, PhD, Jason T. Lee, MD

“…This study sought to use patient-specific computational flow simulation (CFS) to assess differences in postoperative hemodynamic effects associated with fEVAR vs bEVAR. Methods: Patients from two institutions who underwent four-vessel fEVAR with the Cook Zenith Fenestrated platform and bEVAR with the Jotec E-xtra Design platform were retrospectively selected. …”
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In vitro Study of Fungus-Like Organisms Peronospora ficariae and Wilsoniana bliti as Potential Inhalant Allergens by Sztandera-Tymoczek M, Wdowiak-Wróbel S, Świderska U, Palusińska-Szysz M, Szuster-Ciesielska A

“…This research sought to explore the potential of two fungus-like species from the Peronosporales (Peronospora ficariae) and Albuginales (Wilsoniana bliti) to induce a proinflammatory response in vitro models of the upper and lower respiratory tract.Materials and Methods: BEAS-2B and A549 cell lines were used to mimic upper and lower respiratory epithelial cells. …”
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Expression characteristics of miR-502-5p/p53/NF-κB signaling pathway in patients with different degrees of knee osteoarthritis: a cross-sectional observational study with methodolo... by Xiaozhe Zhang, Kesong Shi, Anmin Ruan, Pu Chen, Tao Zhang, Qingpu Wang

“…This study aimed to investigate the expression patterns and correlations of the miR-502-5p/p53/NF-κB signaling pathway in KOA synovial tissue across different disease severities. Methods This cross-sectional observational study enrolled 80 KOA patients undergoing knee arthroscopy from March 2019 to October 2019, stratified by Kellgren-Lawrence (KL) grades (20 patients per grade). …”
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Acupuncture effects of post-stroke thalamic pain: a systematic review and meta-analysis of randomized controlled trials by Tianwei Zhang, Tianwei Zhang, Junying Zhai, Junying Zhai, Ling Cheng, Ling Cheng, Kaixin Jiang, Kaixin Jiang, Dayang Wang, Huawei Shi, Bin Wang, Xing Chen, Xinglu Dong, Li Zhou

“…This systematic review and meta-analysis aimed to evaluate the efficacy and safety of acupuncture treatment for PS-TP.MethodsAccording to the established search strategy, randomized controlled trials (RCTs) of acupuncture therapy for PS-TP were retrieved from eight Chinese and English databases as well as two clinical trial registration platforms, up to February 2024. …”
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Capabilities of Dynamic Magnetic Resonance Angiography in Patients With Cerebral Aneurysms in the Postoperative Period by D. O. Kardailskaya, E. I. Zyablova, T. N. Trofimova, I. N. Sever, D. V. Litvinenko, V. V. Tkachev, V. A. Pоrhanov

“…Magnetic resonance angiography (MRA) has recently become increasingly attractive for the follow-up of surgically treated CAs because it is noninvasive, does not require hospitalization, and reduces complications associated with the frequent use of cerebral angiography.Objective: To evaluate capabilities of dynamic MRA in postoperative monitoring of patients with CAs.Materials and methods: The study was conducted at the premises of the Scientific Research Institute – Ochapovsky Regional Clinical Hospital No. 1 (Krasnodar, Russian Federation). …”
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Problematic Social Media Use, Self-Objectification, and Body Image Disturbance: The Moderating Roles of Physical Activity and Diet Intensity by Çınaroğlu M, Yılmazer E

“…It also explores the psychological outcomes of depression and anxiety.Methods: A cross-sectional study was conducted with 594 women aged 18– 65 in Istanbul, Türkiye. …”
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Application of auricular acupoint scraping therapy in postoperative patients with lower extremity fracture (耳穴推刮术在下肢骨折术后患者中的应用) by GUI Huiqiong (桂辉琼), WANG Yihua (王一华), YUAN Qingna (袁庆娜), JI Chen (冀晨), YANG Yihua (杨毅华)

“…Objective To observe the effect of auricular acupoint scraping therapy on postoperative pain and sleep quality of patients with lower extremity fracture. Methods Totally 70 cases of patients undergoing surgery for lower limb fracture were randomly divided into control group and observation group, with 35 cases in each group. …”
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Effect of bagging on nutritional quality and mineral element content of peach fruit in different varieties by CHEN Meng, ZHANG Xue, LI Yue, LI Yong, CHEN Xiaolong, CHEN Jian, YU Xiangyang

“…The study aimed to evaluate the impact of bagging on the nutritional quality and mineral element content of peach fruit in various varieties. [Methods] Three peach varieties from Jiangsu including Baifeng, Xiacui, and Xiahui were tested. …”
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CD79A and GADD45A as novel immune-related biomarkers for respiratory syncytial virus severity in children: an integrated machine learning analysis and clinical validation by Juan Juan Chen, Zhang Ze Lu, Yu Xin Jing, Xing Mei Nong, Yi Qin, Jin Yang Huang, Na Lin, Jie Wei

“…Herein, we investigated the differential expression biomarkers between RSV infected hospitalized patients, healthy groups and RSV infected outpatients.MethodsTwo publicly available transcriptomic datasets (GSE77087 and GSE188427) were retrieved from the Gene Expression Omnibus (GEO) database. …”
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Kirjeldamisest lavastamiseni. Loovuurimuslik vaade / From Describing to Staging: A Practice-as-Research Look by Karl Saks, Hedi-Liis Toome, Anu Sööt, Ele Viskus

“…The research shows that using ekphrasis and thin and thick description—methods used in other fields—is a fruitful practice and the description based exercises are later useful in their professional career as directors. …”
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Evaluation of the efficacy of high molecular weight hyaluronic acid with chondroitin sulfate in post-traumatic knee osteoarthritis by E. I. Bialik, M. A. Makarov, V. A. Nesterenko, V. E. Bialik, A. E. Karateev, A. A. Bialik, V. I. Stadnik

“…Objective: to evaluate the efficacy of a single or double administration of a preparation of high molecular weight hyaluronic acid (HLA) with chondroitin sulfate (CS) in post-traumatic knee osteoarthritis (OA). Material and methods. The study included 91 patients with stage III post-traumatic knee OA. …”
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Damage to the Cardiovascular System in Patients with SARS-CoV-2 Coronavirus Infection. Part 2: Correction of Myocardial Systolic Dysfunction by V. I. Podzolkov, A. I. Tarzimanova, A. E. Bragina, I. I. Shvedov, E. E. Bykova, A. A. Ivannikov, L. V. Vasilyeva

“…To study changes in myocardial contractile function when prescribing mineralocorticoid receptor antagonists of spironolactone in patients after coronavirus infection SARS-CoV-2 with symptoms of chronic heart failure (CHF).Materials and methods. The study included 90 hospitalized patients with a diagnosis of SARS-CoV-2 coronavirus infection. …”
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Overcoming challenges and achieving high HPV vaccination uptake in Cameroon: lessons learned from a gender-neutral and single-dose program and community engagement by Andreas Ateke Njoh, Dur-E-Nayab Waheed, Tchokfe Shalom Ndoula Josue Kedakse, Lionel Junior Ebongue, Eugene Justine Kongnyuy, Adidja Amani, Afizu Chrakoh Tambasho, Yauba Saidu, Mohamed II Kaba, Clovis Nchinjoh Sangwe, Herman Kenfack, Judith Seungue, Daniel Nebongo, Nadege Edwige Nnang, Alex Vorsters, Laurent Cleenewerck de Kiev

“…This paper highlights the challenges, lessons learned, and progress in HPV vaccination as part of Cameroon’s gender-neutral-single-dose approach and the periodic intensification of routine immunization (PIRI). Methods This ecological cross-sectional study, conducted from July to December 2023, examines the introduction of the HPV vaccine in Cameroon, along with associated challenges, strategies, and progress. …”
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