Effectiveness of Local Wound Infiltration with Morphine, Ketorolac, and Bupivacaine Compared to Bupivacaine Alone Following Tibial Osteotomy in Pediatric Patients: A Randomized Con... by Piyanuch Musikachart, Thanase Ariyawatkul, Jidapa Wongcharoenwatana, Nath Adulkasem, Perajit Eamsobhana

“… Objective: To compare postoperative pain in children receiving ketorolac plus morphine local wound infiltration as adjunct analgesic agents with bupivacaine for local wound infiltration following tibial osteotomy. Materials and Methods: This randomized, double-blind, placebo-controlled trial included patients aged 7-15 years who underwent tibial osteotomy. …”
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Efficacy and safety of first-line or second-line selective laser trabeculoplasty for normal-tension glaucoma: a multicentre cohort study by Tomoko Naito, Kazuyuki Hirooka, Toru Nakazawa, Masaki Tanito, Shiro Mizoue, Katsuyoshi Suzuki, Keiji Yoshikawa, Itaru Kimura, Yasushi Ikuno, Takako Miki, Kazuhisa Sugiyama, Tairo Kimura, Akiko Narita, Tadashi Nakano, Tomoyuki Watanabe, Koji Nitta, Kae Sugihara, Maki Katai, Takuji Matsuda, Hiroaki Ozaki, Kaori Komatsu, Yoshiaki Saito, Takeshi Sagara, Aika Tsutsui, Akiko Ishida, Satoru Tsuda, Toyoaki Tsumura, Naoki Tojo, Naoto Tokuda, Kenji Nakamoto, Naka Shiratori, Mami Nanno, Naoya Nezu, Yoshitaka Tasaka, Shigeru Mori, Shigeki Yamabayashi, Kimihito Konno, Miyuki Domoto

“…Background/aims This study aimed to investigate and compare the efficacy and safety of first-line and second-line selective laser trabeculoplasty (SLT) in Japanese patients with normal-tension glaucoma (NTG).Methods 100 patients with NTG were enrolled in this study. …”
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Individual-level characteristics and geospatial factors associated with cervical cancer screening participation in Alberta, Canada: a population-based cross-sectional study by Jessica Law, Geneviève Jessiman-Perreault, Amanda Alberga Machado, Linan Xu, Bonnie Chiang, Huiming Yang, Lisa Allen Scott, Rizwan Shahid, Curtis Mabilangan, Alvin Li, Kamala Adhikari, Gary Teare

“…This study aimed to identify these characteristics related to cervical cancer screening status. Methods The study population included women between the ages of 28 to 69 years in Alberta. …”
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Focal liver lesions: multiparametric microvasculature characterization via super-resolution ultrasound imaging by Qian-Qian Zeng, Shi-Zhe An, Chao-Nan Chen, Zhen Wang, Jia-Cheng Liu, Ming-Xi Wan, Yu-Jin Zong, Xiao-Hua Jian, Jie Yu, Ping Liang

“…Methods Patients with FLLs between June 2022 and February 2023 were prospectively screened. …”
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Combinations of polymorphisms in the regulatory regions of cytokine genes are associated with diabetic retinopathy in type 2 diabetic patients by V. I. Konenkov, A. V. Shevchenko, V. F. Prokof`ev, V. V. Klimontov, N. V. Tyan, V. V. Chernykh, D. V. Chernykh, A. V. Eremina, A. N. Trunov

“…Accordingly, we aimed to assess the frequencies of combinations of SNPs from promoters of cytokine genes in type 2 diabetic subjects with and without DR.Materials and methods: We enrolled 201 caucasian subjects with type 2 diabetes, including 90 ones with non-proliferative or preproliferative retinopathy and 111 subjects without DR. …”
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The Swiss Endometriosis Database: a retrospective multicentre cohort study on pain levels and multimodal treatment needs of endometriosis patients by Sara Imboden, Selina Lang, Antonalla Martino, Peter Martin Fehr, Lea Duempelmann, Cloé Vaineau, Heike Willi, Nicolas Samartzis, Simone Kamm, Dimitri Sarlos, Stephanie Verta, Tina Rohrbach, Christian Polli, Alexandra Kochanowski, Michael Mueller

“… STUDY AIMS: This study aimed to deepen the understanding of endometriosis symptoms, types, and therapy recommendations for Swiss endometriosis patients in Swiss-certified endometriosis centres in 2022. METHODS:In this exploratory retrospective multicentre cohort study, data from 3538 women who had their first consultation at a certified endometriosis centre in Switzerland in 2022 were analysed retrospectively. …”
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Erector spinae plane block versus transversus abdominis plane block with rectus sheath block for postoperative analgesia in laparoscopic hepatectomy: a randomized clinical trial by Mengke Liu, Xuan Mo, Ruonan Zhan, Han Wang, Yangxi Zhao, Yi Zhang

“…This study aims to compare the efficacy of bilateral ultrasound-guided ESPB versus subcostal TAPB with RSB for postoperative analgesia, addressing the gap in current research and optimizing pain management strategies for this procedure. Methods Sixty patients scheduled for laparoscopic hepatectomy were randomly divided into two groups: E group received ultrasound-guided ESPB, while the TR group received subcostal TAPB with RSB. …”
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Am I attached? A patient-partnered approach to creating infographics about attachment to primary care in Ontario, Canada by Maggie MacNeil, Aya Tagami, Peter Sheffield, Vivian R. Ramsden, Joan Barker, Jennifer Boyle, Clare Cruickshank, Eliot Frymire, Richard H. Glazier, Anita Gombos Hill, Michael E. Green, Mary Huang, Marijke Jurriaans, Caron Leid, Melissa McCallum, Sarah Precious, Jo-Ann Stans, Julie Vizza, Murray Walz, Sue Wilkins, Rebecca Ganann

“…Our approach to engaging patients prevented both oversimplification and unnecessary complexity in a public-facing visual about attachment to primary care.…”
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The Effect of Polymorphisms in the CYP2D6 and CYP2C9 Genes on the Clinical Efficacy of Tramadol and Ketorolac When Using the Accelerated Recovery Protocol in Patients With Uncompli... by A. A. Muradyan, D. A. Blagovestnov, D. A. Sychev, P. A. Yartsev, M. L. Rogal, L. N. Kerimova, V. T. Koroshvili, I. A. Yepifanova

“…Analgesic efficacy was assessed using a visual analog scale (VAS) and McGill Pain Questionnaire.Results. …”
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Episode-specific cortical functional connectome reorganization and neurobiological correlates in bipolar disorder: a cross-sectional study by Xiaobo Liu, Bin Wan, Xi-Han Zhang, Ruifang Cui, Siyu Long, Ruiyang Ge, Lang Liu, Jinming Xiao, Zhen-Qi Liu, Jiadong Yan, Ke Xie, Meng Yao, Xin Wen, Sanwang Wang, Yujun Gao

“…The mBD showed expanded visual and prefrontal regions but compressed motor and precuneus regions. …”
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Melanin-concentrating hormone attenuates the hedonic feeding induced by orexin-A in the ventral tegmental area of high-fat diet male mice by Xiaoning Liu, Xiaoning Liu, Helin Yang, Wenguang Xu, Xuezhe Wang, Wenhui Tang, Xiaoxuan Wang, Yang Jiao, Xinchi Luan, Pengmeng Li, Feifei Guo

“…This study aims to investigate the modulatory role of MCH and OX-A in hedonic feeding within the VTA of high-fat diet (HFD) mice.MethodsMale mice were subjected to an 8-week high-fat diet. …”
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Comparison of clinical effectiveness between stapled transanal rectal resection and procedure for prolapse and hemorrhoids for young male patients with prolapsed hemorrhoids by Pei Yan, Gao Jihua, Qi Wenyue, Tian Maosheng, Wu Qiong, Duan Bingqian, Wang Ran, Liu Ziyi

“…[Objectives] To compare the clinical effectiveness between stapled transanal rectal resection (STARR) and procedure for prolapse and hemorrhoids (PPH) for young male patients with prolapsed hemorrhoids. [Methods] This was a retrospective analysis of 84 young male patients with prolapsed hemorrhoids who were treated at the Department of Colorectal Surgery, The First Affiliated Hospital of Hebei College of Chinese Medicine, between January 2019 and December 2019. …”
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Psychiatric drugs dispensing trends in the affected population following Brumadinho dam failure by Marcelo Farah Dell'Aringa, Gabriel Elias Correa-Oliveira, Francesco Della Corte, Luca Ragazzoni, Ives Hubloue, Virginia Murray, Thais Piazza, Claudia Garcia Serpa Osorio-de-Castro, Elaine Miranda, Francesco Barone-Adesi

“…This study aims to investigate the impact of this disaster in the dispensing of psychiatric drugs.MethodsWe evaluated monthly aggregated data from 12 months before to 12 months after the event from two data sources, one accounting for psychiatric drugs dispensed by private pharmacies and the other by public health services. …”
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Global trends and interdisciplinary insights in Tai Chi research: a bibliometric analysis (2004–2024) by Bei Li, Xiwei Zhu, Xiwei Zhu, Xiwei Zhu, Haoli Zhang, Su Zhang, Yanwei Li, Shuxi Wu, Shuxi Wu, Shuxi Wu, Jie Han, Jie Han, Jie Han

“…Therefore, a bibliometric analysis of Tai Chi literature can help us better understand the research status and development trends in this field.MethodsThe article and commentary on Tai Chi from 2004 to 2024 were retrieved from the Web of Science Core Collection. …”
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Performance and Safety of a Sodium Hyaluronate, Xanthan Gum, and Osmoprotectants Ophthalmic Solution in the Treatment of Dry Eye Disease: An Observational Clinical Investigation by Mercedes Molero Senosiaín, Barbara Burgos-Blasco, Pilar Perez-García, Álvaro Sánchez-Ventosa, Marta Villalba-González, María Dolores López Pérez, José Carlos Díaz, Vanesa Díaz-Mesa, Alberto Villarrubia Cuadrado, Enrique Artiaga Elordi, Jose Manuel Larrosa Poves, Alejandro Blasco, Antonio Mateo, Claudine Civiale, Laura Bonino, Antonio Cano-Ortiz

“…To evaluate the clinical performance and safety of a hypotonic ophthalmic solution containing sodium hyaluronate 0.2%, xanthan gum 0.2%, and osmoprotectants (glycine and betaine) for treating DED. Methods This multicenter, prospective, observational clinical investigation included 35 subjects treated with one drop of the ophthalmic solution four times daily. …”
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Performance Comparison of 10 State-of-the-Art Machine Learning Algorithms for Outcome Prediction Modeling of Radiation-Induced Toxicity by Ramon M. Salazar, PhD, Saurabh S. Nair, MS, Alexandra O. Leone, MBS, Ting Xu, PhD, Raymond P. Mumme, BS, Jack D. Duryea, BA, Brian De, MD, Kelsey L. Corrigan, MD, Michael K. Rooney, MD, Matthew S. Ning, MD, Prajnan Das, MD, Emma B. Holliday, MD, Zhongxing Liao, MD, Laurence E. Court, PhD, Joshua S. Niedzielski, PhD

“…Figures were generated to visually compare the performance of the algorithms. …”
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Prediction of EGFR mutations in non-small cell lung cancer: a nomogram based on 18F-FDG PET and thin-section CT radiomics with machine learning by Jianbo Li, Qin Shi, Yi Yang, Jikui Xie, Qiang Xie, Ming Ni, Xuemei Wang, Xuemei Wang

“…BackgroundThis study aimed to develop and validate radiomics-based nomograms for the identification of EGFR mutations in non-small cell lung cancer (NSCLC).MethodsA retrospective analysis was performed on 313 NSCLC patients, who were randomly divided into training (n = 250) and validation (n = 63) groups. …”
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The interdependence of mid-trimester blood pressure and glucose levels in shaping fetal growth and neonatal outcomes: implications for risk–benefit assessment and co-management by Lijuan Lv, Jingbo Yang, Linjie Li, Chuanyi Huang, Huihua Shi, Yiwen Fang, Lushu Zuo, Ting Liu, Hongli Duan, Jiying Wen, Qing Yang, Amanda Henry, Cha Han, Aihua Yin, Xin Zhou

“…How the interdependence of blood pressure (BP) and glucose levels quantitatively influences risk patterns for abnormal fetal growth and neonatal complications remains unexplored. Methods Maternal BP and fasting plasma glucose (FPG) levels were measured between 20 and 28 weeks of gestation in a cohort including 56,881 singleton pregnancies. …”
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Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema: a prospe... by Yao-Yao Sun, Jie Meng, Shan-Shan Li, Qin Xiao, Tian-Zi Zhang, Heng Miao, Ming-Wei Zhao, Hui-Jun Qi

“…AIM: To evaluate the efficacy and safety of concurrent intravitreal ranibizumab (IVR) and extended-release dexamethasone injections (Dex-I) in naïve and refractory patients with retinal vein occlusion macular edema (RVO-ME). METHODS: This was a prospective, interventional, and open-label clinical trial. …”
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Modified double-row suture bridge technique for anterior colliculus fractures combined with deltoid ligament injury: a retrospective study by Jianlong Ni, Zhihao Chen, Wang Wei, Ruiying Li, Dazhi Wang, Dongjian Wang, Zenan Tian, Zhikun Jia, Qichun Song, Meng Feng, Zhibin Shi

“…The purpose of the present study was to describe the application of a modified double-row suture bridge technique and evaluate its early clinical outcomes in the management of anterior colliculus fracture combined with deltoid ligament injury. Methods From 2020 to 2022, 12 patients with anterior colliculus fracture combined with deltoid ligament injury were treated using a modified double-row suture bridge technique. …”
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