USE OF METHOTREXATE IN PATIENTS WITH CALCIUM PYROPHOSPHATE CRYSTAL DEPOSITION DISEASE by M. S. Eliseev, S. A. Vladimirov, E. L. Nasonov

“…Objective: to compare the efficacy of methotrexate (MTX) and colchicine in patients with chronic arthritis in calcium pyrophosphate crystal deposition disease (CPPDD).Subjects and methods. Data from a controlled prospective cross-sectional study of 10 patients (8 women and 2 men) with chronic arthritis in CPPDD are presented. …”
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Effect of Ropivacaine Epidural Block Combined with General Anesthesia on the Expression of Oxidative Stress and Immune Indexes in Elderly Patients with Ovarian Cancer Cell Cytoredu... by Jianmei Yang, Xiaoyan Xu, Lijun Guo, Yuxuan Yan, Huiling Liu

“…This study aims to evaluate the impact of REB combined with GA on oxidative stress and immune parameters in elderly patients undergoing cytoreductive surgery for OC. Methods: Out of 124 eligible patients undergone OC cytoreductive surgery at Lanzhou First People’s Hospital (June 2022–December 2023), 79 patients received intravenous general anesthesia and 45 patients received ropivacaine epidural block combined with general anesthesia. …”
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Impact of Midfoot Charcot Arthropathy (Brodsky Type 1) on Patient Reported Outcome Scores by Seth J. Tysor BS, Christopher E. Gross MD, Daniel J. Scott MBA, MD, Joshua L. Morningstar BS, Joseph Cutrone BS, Michael Otten MD

“…We will compare these values with PROMs from conditions like ESRD, knee and hip arthritis, highlighting Charcot arthropathy's comparable debilitation. Methods: A retrospective chart review identified 67 patients with Brodsky Type 1 Charcot arthropathy by one of two fellowship-trained foot and ankle surgeons at a single academic medical center between years 2015 and 2023. …”
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Thoracic paravertebral block versus local infiltration anesthesia for percutaneous kyphoplasty to treat osteoporotic vertebral compression fractures combined with intercostal neura... by Yimin Li, Haijie Xia, Shucheng Chen, Yunfan Qian, Guangjie Shen, Xiqiang Zhong, Zhiqiang Jia, Chengxuan Tang, Shaoqi He

“…This study aims to compare the efficacy and safety of thoracic paravertebral nerve block (TPVB) and local infiltration (LI) anesthesia for PKP to treat thoracic OVCFs combined with IN. Methods Patients with OVCFs combined with IN scheduled to undergo PKP between January 2021 and June 2022 were randomized into the following groups: TPVB and LI. …”
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Traditional Chinese medicine manual therapy for adolescent idiopathic scoliosis: a case report by Bowen Zhu, Miaoxiu Li, Jun Ren, Tianxiang He, Xin Zhou, Shoujian Wang, Lingjun Kong, Min Fang, Min Fang

“…ObjectivesThis case demonstrates the efficacy and safety of Traditional Chinese Medicine manual therapy (TCMMT) for the treatment of mild to moderate AIS.MethodsAn 10-year-old girl who suffered from low back pain (LBP) with marked shoulder inequality and razorback postural abnormalities, with a clinical diagnosis of idiopathic scoliosis, and the Cobb angle of 20° and angle of trunk rotation (ATR) of the thoracic vertebral segment at 7°, and ATR of the lumbar vertebral segment at 8°, was treated with TCMMT. …”
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Does the blood glucose control have an effect on the success of the painful diabetic neuropathy treatment? by Jovanikić Olivera, Anđelić Gordana, Lepić Milan, Mirković Dušica, Jovanović Bojan, Lepić Toplica, Dragović Tamara

“…We monitored the impact of glucoregulation on the efficacy of painful diabetic neuropathy (PDN) treatment, when all pharmaceutical treatment options were exhausted. Methods. Patients (n = 53, both gender, average age 68.3 ± 12.6) with PDN resistant to the pharmacotherapy were treated with the ultrasound- guided local anesthetic (0.5% procaine hydrochloride, 1% lidocaine, 0.25% levobupivacaine) blocks. …”
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Two-Port Needle-Assisted Pediatric Laparoscopic Herniotomy Using Tuohy Needle: Clinical Experience and Outcomes by Imran Abbas, Rida Fatima, Muhammad Aslam Javed, Muhammad Hassan, Mahmood Farooqi, Muhammad Mohsin Gillani

“…Tuohy Needle-assisted Laparoscopic hernia repair has several advantages over the open repair technique, including shorter recovery times, the ability to evaluate and repair contralateral defects, reduced postoperative complications, and improved outcomes. Methods: This descriptive case series study was conducted in the Department of General Surgery at Sharif Medical City Hospital, Lahore, over a period of six months. …”
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Rhinoplasty without nasal packing and splinting by Vulović Dejan, Kozarski Jevta, Radivojčević Uroš, Stepić Nenad, Milićević Saša, Petrović Nenad T.

“…In assessing postoparative pain, the visual analogue scale (VAS) in a range of 1 to 5 was used. …”
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Examining differences in exposure to digital marketing of unhealthy foods reported by Canadian children and adolescents in two policy environments by Laura Vergeer, Carolina Soto, Mariangela Bagnato, Elise Pauzé, Ashley Amson, Tim Ramsay, Dana Lee Olstad, Vivian Welch, Monique Potvin Kent

“…This study examined differences in self-reported exposure to digital food marketing between children and adolescents in different policy environments: Ontario (where food marketing is self-regulated) and Quebec (where advertising is government regulated). Methods An observational cross-sectional online survey was conducted in April 2023 among children (aged 10–12 years) and adolescents (13–17 years) from Ontario and Quebec, recruited by Leger Marketing. …”
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Çocuklarda Dental Anksiyete: Başarılı Dental Tedavinin Önündeki Engel by Aysun Avşar, Büşra Mutlu

“…In order to progress and complete the steps of dental treatment, anxiety can be managed non-pharmacologically with pharmacological methods such as sedation and general anesthesia, aromatherapy, music therapy, visual and auditory distraction and hypnosis by watching videos during treatment. …”
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Efficacy of Different Doses of Intra‐Articular Tranexamic Acid for Reducing Blood Loss and Lower Limb Swelling After Total Knee Arthroplasty: A Prospective, Randomized, Controlled... by Shuwei Ye, Yue Luo, Qianhao Li, Lijun Cai, Pengde Kang

“…The aim of this trial was to investigate whether different doses of intra‐articular tranexamic acid (TXA) can reduce blood loss and postoperative lower limb swelling. Methods In a prospective, randomized‐controlled trial, a total of 225 patients were randomly assigned to three groups from September 2020 through January 2021: intra‐articular injections of 3 g, 1 g of TXA, or placebo (saline solution). …”
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Innovative machine learning-based prediction of early airway hyperresponsiveness using baseline pulmonary function parameters by Hua Yang, Xingru Zhao, Zhuochang Chen, Lihong Yang, Guihua Zhao, Chenxiao Xu, Jinyi Xu

“…This study explores the potential of baseline pulmonary function parameters, particularly small airway indices, in predicting AHR and develops a machine learning-based model to improve screening efficiency and reduce unnecessary BPT referrals.MethodsThis retrospective study analyzed baseline pulmonary function data and BPT results from Henan Provincial People’s Hospital (May to September 2024). …”
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The impact of anterior cruciate ligament deficiency severity on the outcomes of fixed-bearing unicompartmental knee arthroplasty: a retrospective study by Shuhan Jia, Di Long, Bo Zhang, Mingyang Sun, Fengji Liu, Yixuan Jiao, Guoan Wang, Bin Zhang

“…This study aimed to evaluate the impact of varying severities of ACLD on the clinical outcomes of FB-UKA. Methods This retrospective analysis included 81 patients (87 knees) who underwent FB-UKA for anteromedial osteoarthritis (AMOA). …”
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Efficacy of Bilateral Transverse Abdominis Plane Block and Ilioinguinal Iliohypogastric Nerve Block for Post Lower Segment Caesarean Section Pain Relief: A Randomised Clinical Stud... by Jigisha Bharatbhai Mehta, Gayatri Vasagadekar, Sara Mary Thomas

“…Aim: To compare the efficacy of bilateral Transverse Abdominis Plane block (TAP) and Ilioinguinal Iliohypogastric block (II-IH) for postcaesarean section pain relief. Materials and Methods: A randomised clinical study was conducted at Dhiraj Hospital, Piparia, Vadodara, Gujarat, India, on 60 pregnant women, aged between 18 to 45 years, who were posted for elective Lower Segment Caesarean Section (LSCS). …”
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Improving frailty documentation from admission to discharge: a quality improvement project in an elderly care ward by Thomas Kirwin, Carmel Halevy, Yass Hatahet, Jan Chiu, Iris Soteriou, Marcus Geyer, Ruth Mizoguchi, Iraida Safiulova

“…Key components of CGA, including Treatment Escalation Plans (TEPs), Universal Care Plans (UCPs), and the Abbreviated Mental Test Score (AMTS), have pivotal roles in recognising frailty, guiding appropriate management and ensuring holistic care from hospital to community settings. Methods: A retrospective analysis of documentation of three CGA parameters (TEP, UCP and AMTS) in clinical notes on admission to a Care of the Elderly Care ward was conducted over four cycles. …”
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Efficacy and Safety of Tranexamic Acid on Hidden Blood Loss in Osteoporotic Vertebral Compression Fractures Patients Treated with Percutaneous Kyphoplasty: A Prospective Randomized... by Lou Z, Jiang K, Xia S, Chen S, Jiang Y, Zhu J, Zhu J

“…HBL was calculated and compared on postoperative days 1 (POD1) and 3 (POD3). Visual analog scale (VAS) scores were also recorded preoperatively and during the follow-up. …”
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Comparison of surgical efficacy between direct anterior approach and posterolateral approach in the treatment of sarcopenia with femoral neck fractures by Zhaoyang Yin, Qin Hu, Bin Zhang, Jin Yi, Hailong Zhang, Jian Yin

“…This study aims to compare the effects of the DAA and the posterolateral approach (PLA) on the efficacy of TJA surgery in patients with FNF who also present with sarcopenia. Methods This study retrospectively analyzed the clinical data of patients with FNF who underwent total hip arthroplasty (THA) using either DAA or PLA from December 2019 to December 2022. …”
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Reliability of the electronic patient reported outcome measures for assessing xerostomia, dysphagia and quality of life in Spanish patients with head and neck cancer: a randomised... by Mario Lozano-Lozano, Maria Lopez-Garzon, Paula Cuadrado-Guerrero, Paula Postigo-Martin, Carolina Fernández-Lao, Isabel Tovar-Martín, Noelia Galiano-Castillo

“…We hypothesised notable reliability and equivalence between the two modalities. Methods A total of 24 patients (median age 63.00 years, undergone radiotherapy, either alone or in combination with surgery and/or chemotherapy, and suffering xerostomia) were randomised to either paper-based (PROM) or ePROM in a two-arm crossover design with a within-subject comparison of the two modalities (washout period 90 min). …”
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OncoPSM: an interactive tool for cost-effectiveness analysis using partitioned survival models in oncology trial by Xulong Qiu, Xulong Qiu, Jidi Chen, Jidi Chen, Muting Wang, Kaixin Zheng, Ruixiong Li

“…However, many CEA tools are not specifically tailored to address the intricate cost composition resulting from the complex treatment regimens in oncology trials.MethodsWe extracted data from Kaplan-Meier (KM) curves, reconstructed individual patient data (IPD) using an iterative KM algorithm, and fitted parametric survival functions to the IPD data. …”
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Modifying reaction time tasks parameters in the automated IntelliCage identifies heightened impulsivity and impaired attention in the 3xTg-AD model of Alzheimer’s disease by Jessica M. Judd, Wendy Winslow, Ian McDonough, Faizan Mistry, Ramon Velazquez, Ramon Velazquez, Ramon Velazquez

“…Each of the four corners of a cage contains doors to manipulate access to water, visual LED cues, and a valve allowing administration of an air puff. …”
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