Clinical efficacy of AUSS/UNSES-TLIF in the treatment of single-segment degenerative lumbar spinal stenosis: a retrospective study by Zhide Liu, Shiyuan Hao, XiangLong Li, En Song, Yabo Yao

“…Abstract Objective To explore the clinical efficacy and advantages of Arthroscopic-assisted Uni-portal Spinal Surgery (AUSS)-Transforaminal Lumbar Interbody Fusion (TLIF) in the treatment of degenerative lumbar spinal stenosis (LSS). Methods This study included 71 patients with lumbar spinal stenosis who underwent surgical treatment at the Department of Spine Surgery, Second Affiliated Hospital of Xi’an Medical University, between January 2022 and December 2023. …”
Get full text

Research Progress and Prospects of Urban-Rural Integration Based on Scientific Knowledge Map by Gong Weixia, Ma Shujiao

“…This study employed CiteSpace software to visually analyze 2,164 papers on urban-rural integration between 2002 and 2023 from the CNKI database. …”
Get full text

Comparative Evaluation of Efficacy and Complications Between Biportal Endoscopic Lumbar Interbody Fusion and Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar De... by Hu Q, Xiao K, Nan JN, Jhang SW, Chen CM, Lin GX

“…The evaluative framework encompassed a diverse array of parameters, including but not limited to operation time, hospitalization, quantification of estimated blood loss, the assessment of outcomes via the application of the Visual Analog Scale (VAS) to gauge pain intensity, and the utilization of the Oswestry Disability Index (ODI) to measure functional impairment.Results: The current meta-analysis included ten studies with a total of 736 participants. …”
Get full text

Comparison of [18F]fluorodeoxyglucose and [68Ga]Gallium DOTA-TATE in patients with active giant cell arteritis by Alison H. Clifford, Jonathan Abele, Ryan Hung, Frank Wuest, Jan Andersson, Susan Pike, Elaine Yacyshyn, Eric Lenza, Glen Jickling, Paolo Raggi, Jan Willem Cohen Tervaert

“…We aimed to compare [68Ga]Ga-HA-DOTA-TATE, a somatostatin 2-analogue tracer, to [18F]FDG in a pilot study of patients with GCA. Methods Eight patients with active GCA were prospectively, sequentially scanned with both [18F]FDG PET/CT and [68Ga]Ga-HA-DOTA-TATE PET/CT imaging. …”
Get full text

Correlation analysis between preoperative odontoid incidence and clinical outcomes 2 years after anterior cervical discectomy and fusion by Yan Gong, Hao Liu, Yanchi Gan, Jiahui He, Zelin Zhou, Hang Zhuo, Yu Liu, De Liang, Hui Ren, Xiaobing Jiang, Zhaojun Cheng

“…Abstract Objective This study presents a novel odontoid parameter, the odontoid incidence (OI), to examine the correlation between OI on preoperative cervical sagittal radiographs and 2-year clinical outcomes following short-segment anterior cervical discectomy and fusion (ACDF) in patients with cervical spondylotic myelopathy (CSM). Methods A retrospective analysis of the clinical data of 87 patients with CSM who underwent ACDF surgery from January 2018 to December 2023 was conducted. …”
Get full text

Influence of herbicide Granstar Pro 75, w.g., in vitro conditions on the seed growth of Amarantus retroflexus L. by I. Storchous

“…., regarding its effect on the germination of Amaranthus retroflexus L. seeds, to ensure targeted and rational use in wheat crops, with maximum preservation of the crop and minimal environmental impact. Methods. Laboratory, visual, computational and comparative, mathematical and statistical. …”
Get full text

Trends and determinants of female genital mutilation prevalence among women of reproductive age in Tanzania and Kenya: a demographic and health survey analysis (2008–2022) by Dotto Daniel Kisendi, D. Lyakurwa, Heavenlight A. Paulo, Elizabeth Malingumu, Virna Vong, E. Matthews, Ebrima Huma, Mgole Eliud Mkama, kang Wu, Yili Zhang, Bei Li

“…Therefore, the study seeks to examine the socio-economic/demographic determinants of FGM in Kenya and Tanzania to inform more targeted interventions. Methods A retrospective analysis of Demographic and Health Survey (DHS) data from 6,517 women aged 15–49 in Kenya and Tanzania (2008–2022) was conducted. …”
Get full text

GAN-enhanced deep learning for improved Alzheimer's disease classification and longitudinal brain change analysis by Purushottam Pandey, Surbhi Bhatia Khan, Surbhi Bhatia Khan, Surbhi Bhatia Khan, Jyoti Pruthi, Eid Albalawi, Ali Algarni, Ahlam Almusharraf

“…Early detection is crucial to mitigate the devastating impacts of AD, which can significantly impair a person's quality of life. Traditional methods for diagnosing AD, while still in use, often involve time-consuming processes that are prone to errors and inefficiencies. …”
Get full text

Investigation of the Potential Association Between Atherosclerotic Cardiovascular Disease Risk Score and Diabetic Retinopathy in Patients with Type 2 Diabetes: A Cross-Sectional St... by Chrysa Agapitou, Theodoros N. Sergentanis, Effie G. Papageorgiou, Panagiotis Theodossiadis, Ignatios Ikonomidis, Vaia Lambadiari, Irini Chatziralli

“…<b>Purpose</b>: To examine the association between diabetic retinopathy (DR) and the atherosclerotic cardiovascular disease (ASCVD) risk score using the “ASCVD Risk Estimator Plus” tool in patients with type 2 diabetes mellitus (DM) and to assess risk factors potentially associated with DR. <b>Methods</b>: Participants in the study included 181 patients with type 2 DM who underwent a thorough ophthalmic examination, including a best-corrected visual acuity (BCVA) measurement, a dilated fundoscopy, fundus photography, an optical coherence tomography (OCT), and an OCT-angiography (OCT-A). …”
Get full text

The Spectrum of Ocular Diseases in the Onchocerciasis-Endemic Focus of Raga in South Sudan by Sube KL, Lako JDW, Tongun JB, Gerber T, Mamur JP, Hamid Moto SJ, Jada SRL, Siewe Fodjo JN, Hopkins AD, Mackenzie CD, Colebunders R

“…The objective of this study was to determine the causes of eye disease and blindness in Raga County as well as to assess the relationship of eye diseases with other prevalent conditions like onchocerciasis and epilepsy.Methods: We reviewed unpublished pre-community directed treatment with ivermectin (CDTI) data about eye disease and onchocerciasis in Western Bahr El Ghazal including Raga. …”
Get full text

Comparative Efficacy of Carbamazepine Therapy With and Without Transcutaneous Electrical Nerve Stimulation Therapy in Trigeminal Neuralgia Patients: A Randomised Controlled Trial P... by Rutumbara Gajanan Dhone, Vidya Krunshnarao Lohe

“…Aim: To evaluate and compare the efficacy of CBZ therapy with and without TENS therapy for the management of TN. Materials and Methods: A Randomised Controlled Trial (RCT) will be conducted in the Outpatient Department (OPD) of Oral Medicine and Radiology at Sharad Pawar Dental College and Hospital, Wardha, Maharashatra, India between July 2024 and May 2026. …”
Get full text

Kinematic and kinetic features of an unaffected limb during walking in children with spastic hemiplegia by Ulvi F. Mamedov, Tamara I. Dolganova, Lidiia V. Smolkova, Anatoly O. Trofimov, Orkhan I. Gatamov, Dmitry A. Popkov

“…Objective To determine the features of compensatory and adaptive behavior of the limb not involved in the pathogenesis in children with hemiplegia during walking and their dependence on age and previous surgical interventions on the triceps surae. Materials and methods Locomotor characteristics of 78 children under 16 years of age with spastic hemiplegia and motor disorders corresponding to levels I–II GMFCS (Gross Motor Function Classification System) were compared with 77 healthy peers. …”

Short-term outcomes of faricimab and aflibercept 8 mg in diabetic macular edema by Carlo Maccauro, Yanny Jimenez Perez, Piergiorgio Neri, Ibraheem El Ghrably, Haytham I Salti, Francesco Pichi

“…Patients were selected based on clinical and imaging criteria confirming the presence of center-involving DME requiring anti-vascular endothelial growth factor (VEGF) therapy. Methods: Patients received loading doses of either four monthly faricimab injections or three aflibercept 8 mg injections and were followed for a total of approximately 6 to 9 months, including both loading and PRN phases. …”
Get full text

Chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels: a network analysis on 2018 CHARLS data by Qiaofeng LI, Yilong YAN, Yuehan HE, Yongtai LI, Guowu DING

“…ObjectiveTo understand the chronic disease comorbidities among middle-aged and elderly Chinese population with different depression levels and provide a scientific basis for optimizing depression screening and chronic disease prevention and treatment. MethodsData from 14 222 middle-aged and elderly individuals aged ≥ 45 years old were collected from the 2018 China Health and Retirement Longitudinal Study (CHARLS). …”
Get full text

Dry Eye Epidemiology in Patients before Refractive Operations by S. N. Sakhnov, S. V. Yanchenko, A. V. Malyshev, Y. A. Kalantaevskaya, R. A. Ismaylova, E. M. Ehieva, M. V. Grishenko, I. V. Gorbunova, O. F. Ozhug, O. A. Klokova

“…To evaluate the prevalence, clinical severity, clinical and pathogenetic variants and etiology of dry eye (DE) in patientsbefore refractive surgery. Methods. OSDI testing, lipid interferential test, TBUT, Shirmer-1, -2 tests, compression Norn test in Korbmodification, calculation of xerosis index by Bijsterveld, tear meniscus index evaluation, LIPCOF test, evaluation of epitheliopaty and microerosion by Tseng and lid viper epitheliopaty were performed in 600 myopia (with or without astigmatism) patients (234 men, 366 women; 30.1 ± 6.26 years old) before refractive surgery. …”
Get full text

Comparative study on the quality of life and clinical efficacy of orthokeratology lens, defocus spectacle lens and single vision spectacles in myopic children and adolescents in Ch... by Sile Yu, Wei He, Yang Li, Tingting Zhao, Li Lin, Xiaonan Liu, Jiayan Chen, Guanghao Qin, Xingru He, Ruyi Li, Yibing Zhou

“…Purpose To evaluate and compare the vision-related quality of life and efficacy between myopic children and adolescents wearing orthokeratology (OK) lens, defocus spectacle (DS) lens and single vision spectacle (SVS).Methods This ambispective cohort study involved 93 participants who had worn optical correction lenses (31 OK lens, 31 DS lens and 31 SVS) for 1 year. …”
Get full text

Neuroprotection effect of bovine umbilical mesenchymal stem cell-conditioned medium on the rat model of Alzheimer&apos;s disease mediated by upregulation of BDNF and NGF and downre... by Hevi Wihadmadyatami, Muhammad Ali Zulfikar, Herawati Herawati, Srikanth Karnati, Golda Rani Saragih, Dinda Aliffia, Dyah A.O.A. Pratama, Nurrahmi Handayani, Ulayatul Kustiati, Dewi Ratih Tirtosari, Yudy Tjahjono

“…Aim: This study analyzes the therapeutic efficiency of conditioned medium or secretome produced from BUMSC-CM in treating neurodegeneration in animal models of AD. Methods: Five groups consisting of twenty-five male rats were assigned: untreated (Group A, n=5), positive control group given normal saline 1 ml/100 g BW (Group B, n=5), AD rats model followed by Donepezil treatment (Group C, n=5), AD rats model with BUMSC-CM 0.2 ml/kg BW post-TMT induction (Group D, n=5), and AD rats model with BUMSC-CM 0.5 ml/kg BW post-TMT induction (Group E, n=5). …”
Get full text

Integrating Brain-Computer Interface Systems into Occupational Therapy for Enhanced Independence of Stroke Patients: An Observational Study by Erika Endzelytė, Daiva Petruševičienė, Raimondas Kubilius, Sigitas Mingaila, Jolita Rapolienė, Inesa Rimdeikienė

“…We hypothesized that integrating BCI into occupational therapy would result in measurable improvements in hand strength, dexterity, independence in daily activities, and cognitive function compared to baseline. <i>Materials and Methods</i>: An observational study was conducted on 56 patients with subacute stroke. …”
Get full text

Investigating the Efficacy and Safety of the CyberKnife System for Treating Primary Pancreatic Cancer with Metastases to the Gastrointestinal Tract by Zhang Z, Tian B, Xu H, Huang H, Liang X, Bo C, Bian Y, Wei M, Zhao Z

“…The median OS was 8.17 months (range: 1– 25 months). Mean pain scores (Visual Analog Scale) decreased significantly from 5.38± 1.37 at baseline to 2.01± 0.35 post-treatment (p&lt; 0.001). …”
Get full text

Global insights into the genome dynamics of Clostridioides difficile associated with antimicrobial resistance, virulence, and genomic adaptations among clonal lineages by Mohammad Sholeh, Mohammad Sholeh, Masoumeh Beig, Masoumeh Beig, Ebrahim Kouhsari, Mahdi Rohani, Mohammad Katouli, Farzad Badmasti

“…This study offers a genomic analysis of C. difficile, focusing on sequence types (STs), global distribution, antibiotic resistance genes, and virulence factors in its chromosomal and plasmid DNA.MethodsA total of 19,711 C. difficile genomes were retrieved from GenBank. …”
Get full text