Preserving one artery shortens the surgical time and does not affect the efficacy of microsurgical subinguinal varicocelectomy: preliminary findings from a retrospective study by Xu Cao, Cheng Tian, Wei Feng, Shu-xian Zhu, Kai Chen, Yu-hang Zheng, Jian-zhong Yao

“…Abstract Background To analyze the safety and efficacy of microsurgical subinguinal varicocelectomy(MSV) performed with and without preservation of all testicular arteries and lymphatic system. Methods All of the 98 patients with varicocele who underwent MSV were included in the analysis. …”
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The Effect of Low-Level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-Blind Placebo-Controlled, Split-Mouth Study by Alireza Khandan Dezfully, Márió Gajdács, Aliz Eperke Pató, Krisztina Kárpáti, Melinda Madléna

“…The aim of our study was to evaluate the effect of a single application of LLLT on the experience of pain following ES placement. <b>Methods:</b> A double-blind, placebo-controlled randomized controlled trial was performed—with implementation of the split-mouth technique—where <i>n</i> = 33 volunteers (12 male and 21 female; aged between 19 and 36 years) were enrolled. …”
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Optimal exercise temporal parameters of Traditional Chinese Exercises for cognitive function of older adults with mild cognitive impairment: a systematic review and dose–response m... by Qingpan Wen, Qin Luo, Yangjun Liu, Lu Li, Marcin Białas, Dominika Wilczyńska

“…A dose–response meta-analysis was conducted to evaluate the correlation between exercise temporal parameters and their effectiveness in older adults with MCI.MethodsRandomized controlled trials (RCTs) on TCEs for MCI were searched across eight databases from their inception to September 2024. …”
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Biomechanical and cellular assessment of novel partially demineralized allogeneic bone plates: an ex-vivo and in-vitro study by Philipp Becker, Andreas Pabst, Diana Heimes, Nadine Wiesmann-Imilowski, Sven Schumann, Peer W. Kämmerer

“…Abstract Purpose This study aimed to compare commercial allogeneic cortical bone plates (cCP) with innovative, differently demineralized CP (dCP) in biomechanics and human osteoblast (HOB) viability ex-vivo and in-vitro. Methods Breaking strength (BS; in N) and flexibility (F; in mm) of cCP and dCP were assessed and compared using four groups ((1) non-hydrated, (2) hydrated for 10, (3) 30, and (4) 60 min in saline), respectively. …”
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Construction and validation of a risk prediction model for extensive abdominal aortic calcification in hypertensive patients aged 40 and above: a cross-sectional study based on the... by Shanbing Hou, Ying Jiang, Fangfang Zhao, Zixuan Wei, Tingting Wang, Jing Chen, Min Dou, Lixiang Zhang

“…Methods This study extracted data from the 2013–2014 NHANES database, including 1,564 middle-aged and elderly hypertensive patients who met the inclusion criteria. …”
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Effects of esketamine combined with thoracic paravertebral block on postoperative early sleep in patients undergoing thoracoscopic lobectomy by LI Wenyan, ZHANG Yong, ZHANG Chen, SHI Li

“…Objective To observe the effects of continuous intravenous infusion of esketamine combined with thoracic paravertebral nerve block (TPVB) on postoperative early sleep, analgesia, and recovery quality in patients undergoing thoracoscopic lobectomy. Methods A total of 76 patients scheduled for elective thoracoscopic lobectomy at Nanjing First Hospital from January 2023 to January 2024 were randomly divided into two groups: the control group (C group) and the esketamine group (E group), with 38 patients in each group. …”
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Efficacy and Safety of Non-Pharmacological Therapies for Primary Dysmenorrhea: A Network Meta-Analysis by Liu J, Wang Y, Zhang J, Fan X, Chen H, Zuo G, Wang X, She Y

“…The outcomes were the Visual Analog Scale (VAS), the Cox menstrual symptom scale (CMSS), and response rate. …”
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Design of intelligent human-machine collaborative robot-assisted craniotomy system by Meng Cui, Wenqing Ren, Tengfei Cui, Ruifeng Chen, Yi Shan, Xiaodong Ma

“…Objectives: To develop an intelligent human-machine collaborative control robot-assisted craniotomy system, and test its efficacy by experiments. Methods: The system integrated a UR5 robotic arm (Universal Robots, Denmark), a host computer, a double six-degree-of-freedom force sensor(Nanjing Yuli Instrument Co., Ltd.), a medical drill(AESCULAP®, Germany), a Polaris Optical navigation system(NDI,Canada), with a self-designed navigation procedure and a visual graphical user interface(GUI). …”
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Prediction of radiosensitivity in non-small cell lung cancer based on computed tomography and tumor genomics: a multiple real world cohort study by Peimeng You, Qiaxuan Li, Yu Lei, Chuhao Xu, Daipeng Xie, Lintong Yao, Jiaxin Yuan, Junyu Li, Haiyu Zhou

“…In this research, based on single cell sequence data we used radiomics to help identify and screen feature signatures to distinguish varying radiosensitivity in different regions of the target area of non-small cell lung cancer can provide a new pattern to assess sensitivity of radiotherapy and assist in clinical decision-making. Methods This retrospective study included CT radiology data from 454 patients diagnosed with non-small cell lung cancer in multiple real-world cohorts prior to radiotherapy. …”
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Pooling the complex survey data across the 64 lower and middle-income countries: A study on antibiotic usage in under-five children by Md Fakrul Islam, Prosenjit Basak Arka, Mahfuzer Rohman, Md Sabbir Hossain, Md Rashed Babu, Hasin Anupama Azhari, Md Jamal Uddin

“…As a result, it's crucial to look at the variables that affect antibiotic exposure and highlight the subgroups among whom antibiotic abuse is the most prevalent. Methods: We used the most recent standard Demographic and Health Survey (DHS) data for 64 LMICs. …”
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Clinical efficacy of circular laser half-fistula canal ablation in the treatment of anal fistula by Zhang Feigong, Li Youlong, Yan Hua

“…[Objectives] To observe the clinical efficacy of circular laser half-fistula canal ablation in the treatment of anal fistula. [Methods] A total of 52 patients with anal fistula admitted to Zhabei Central Hospital, Shanghai Jing’an District from July 2019 to December 2020 were selected as the research subjects and randomly divided into an experimental group (n=26) and a control group (n=26). …”
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Prognostic value of ALBI score for all-cause mortality in metabolic associated fatty liver disease patients: a cohort study from NHANES 2003–2018 by Guoxing Zhou, Weiwei Han, Jinhong Luan, Baozhu Ma

“…This study aims to investigate the association between ALBI scores and all-cause mortality in individuals with MAFLD and to evaluate its prognostic potential using large-scale NHANES data. Methods Drawing on data from the population-based National Health and Nutrition Examination Survey (NHANES) conducted between 2003 and 2018, we employed weighted multivariable Cox proportional hazards regression to assess the relationship between ALBI scores and all-cause mortality in a cohort of 5,666 MAFLD patients. …”
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Dynamic nomogram for predicting the overall survival and cancer-specific survival of patients with gastrointestinal neuroendocrine tumor: a SEER-based retrospective cohort study an... by Yipu Wang, Gongning Wang, Chao Song, Wenqian Ma, Xiuli Zheng, Shuo Guo, Qi Wang, Lan Zhang, Limian Er

“…Our study aims to develop and validate two new nomograms to predict the overall survival (OS) and cancer-specific survival (CSS) of GI-net patients and investigate their application value.MethodsSEER*Stat 8.4.4 software was used to download clinicopathological information of GI-net patients between 2010 and 2015 from the Surveillance, Epidemiology, and End Results (SEER) database. …”
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Evaluation of Postoperative Pain in Periodontal Flap Surgery with and without Photobiomodulation using Diode LASER: A Split-mouth Randomised Controlled Study by Neeraj Chandrahas Deshpande, Aayushi Shah, Monali Amit Shah

“…Aim: To evaluate and compare postoperative pain in periodontal flap surgery with and without PBM using a diode laser. Materials and Methods: A split-mouth randomised controlled study was carried out in the Department of Periodontology at KM Shah Dental College and Hospital, Vadodara, Gujarat, India. …”
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Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study by Yilmaz Karaduman, Arzu Muz, Azize Serçe, Servi Yildirim, Ismail Eren Durmus, Suna Akin Takmaz

“…Aim: To evaluate and compare the effectiveness of USG intra-articular ozone therapy versus corticosteroid injections in managing hip OA (coxarthrosis) in patients who have not responded to conventional treatments. Materials and Methods: A retrospective comparative study was conducted at Ankara Training and Research Hospital, Ankara, Altındag, Turkey, from August 2021 to August 2022. …”
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Optical coherence tomography findings as a predictor of clinical course in patients with branch retinal vein occlusion treated with ranibizumab. by Akira Shiono, Jiro Kogo, Hiroki Sasaki, Ryo Yomoda, Tatsuya Jujo, Naoto Tokuda, Yasushi Kitaoka, Hitoshi Takagi

“…<h4>Participants</h4>Thirty eyes of 30 patients with BRVO treated with IVR.<h4>Methods</h4>All patients received 1 initial IVR followed by repeated injections in the pro re nata (PRN) regimen. …”
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Short-Term Effects of Fruit Juice Enriched with Vitamin D3, n-3 PUFA, and Probiotics on Subjective Appetite and Blood Pressure: A Randomized Controlled Clinical Trial in Healthy Ad... by Dionysia-Lydia Bothou, Nikolaos Zacharodimos, Christina Athanasaki, Stamatia Vitsou-Anastasiou, Olga Papadopoulou, Chrysoula Tassou, Emilia Papakonstantinou

“…This study aimed to determine the effects of consuming a mixed commercial FJ (apple, orange, grape, pomegranate; FJ-control) and the same FJ fortified either with 2 probiotics strains (108 cfu/mL Lacticaseibacillus casei Shirota and Lacticaseibacillus rhamnosus GG), 50 μg vitamin D3, 8.33 g n-3 polyunsaturated fatty acids, or with the combination of all of these biofunctional ingredients (vitamin-D3-n-3-probiotics), on subjective appetite and blood pressure (BP). Methods: Clinically healthy volunteers participated in this randomized, double-blind, crossover, controlled trial. …”
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Epidemiology of interpersonal violence among Mexican children and adolescents: a national analysis of injury data from public hospitals from 2015 to 2022 by Magdalena Gruendl, Diana D. del Valle, Letícia Nunes Campos, Theoneste Nkurunziza, Taylor Wurdeman, Tanujit Dey, Arturo Cervantes Trejo, Stefanie J. Klug, Tarsicio Uribe-Leitz

“…We aim to investigate the epidemiology of IPV cases among children and adolescents in Mexico. Methods This retrospective registry-based analysis used a nationwide injury dataset (Lesiones) from the Mexican Ministry of Health. …”
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Efficacy of Resorbable versus Non Eugenol Packs in Enhancing Early Wound Healing following Gingival Excisional Procedures: A Randomised Controlled Study by Lakshmi Ramachandran, Anupama Tadepalli, Priyanka Cholan, Santo Grace Umesh, Harinath Parthasarathy, Chinmaya Agarwal

“…Aim: To clinically evaluate wound healing following the use of a resorbable periodontal dressing following gingival excisional procedures and to compare the outcomes with the conventional COE-PAKTM periodontal dressing. Materials and Methods: A randomised controlled trial was conducted in the Department of Periodontology, SRM Dental College, Chennai, Tamil Nadu, India from June 2022 to March 2023. …”
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Designing novel cabozantinib analogues as p-glycoprotein inhibitors to target cancer cell resistance using molecular docking study, ADMET screening, bioisosteric approach, and mole... by Gajendra Singh Thakur, Ajay Kumar Gupta, Dipti Pal, Yogesh Vaishnav, Neeraj Kumar, Sivakumar Annadurai, Sanmati Kumar Jain

“…Consequently, P-gp has emerged as a critical target for research in anti-cancer therapies.MethodsThe purpose of this study was to computationally identify new andsafer analogues of CBZ using bioisosteric approach, focusing on improved pharmacokinetic properties andreduced toxicity. …”
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