Machine Learning Model for Early Detection of COVID-19 by Heart Rhythm Abnormalities by M. S. Mezhov, V. O. Kozitsin, Iu. D. Katser

“…The possibility of integrating the results obtained with fitness bracelets and smart watches is shown.Materials and Methods. The work involved an open technology stack: Python, Scikit-learn, Lightgbm. …”
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Prognostic factors associated with achieving minimal disease activity in early psoriatic arthritis patients treated according to “treat-to-target” st rategy within 12 months by E. Yu. Loginova, T. V. Korotaeva, E. E. Gubar, S. I. Glukhova

“…But prognostic factors for achievement MDA in PsA patients (pts) at the early-stage hasn’t been studied yet.Objective – to determine the prognostic factors associated with achievement of minimal disease activity within 12 months (mo) of treatment according to T2T strategy in early psoriatic arthritis patients.Methods. 77 pts (M/F=36/41) with early PsA fulfilling the CASPAR criteria were included. …”
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Effects of varying longitudinal bending stiffness in running shoes on lower limb biomechanics of elite marathon runners by Hailiang Yang, Hailiang Yang, Yuhui Cai, Kuang Li, Xiangdong Wang, Tao Liu

“…ObjectiveThis study examined the effect of three levels of longitudinal bending stiffness (LBS) in carbon-plated shoes on lower limb biomechanics.MethodsFifteen elite male marathon runners, each with a personal best under 3 h, participated in the study. …”
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Fluorine-18-Labeled Positron Emission Tomography Probe Targeting Activated p38α: Design, Synthesis, and In Vivo Evaluation in Rodents by Mikiya Futatsugi, Anna Miyazaki, Yasukazu Kanai, Naoya Kondo, Takashi Temma

“…This study aimed to develop and evaluate a novel fluorine-18-labeled positron emission tomography (PET) probe for imaging activated p38α in vivo. <b>Methods:</b> We designed 6-(4-[¹⁸F]fluoro-2-fluorophenoxy)-8-methyl-2-(tetrahydro-2<i>H</i>-pyran-4-ylamino)-pyrido[2,3-<i>d</i>]pyrimidin-7(8<i>H</i>)-one ([¹⁸F]R1487) by replacing a fluorine atom in R1487, which is a highly selective p38α inhibitor, with ¹⁸F. …”
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Unilateral biportal endoscopy versus percutaneous endoscopic lumbar discectomy for lumbar disc herniation: a comparative study of clinical efficacy and radiological outcomes by Dongyue Li, Luming Tao, Xinuo Zhang, Qingjun Su, Bo Yin

“…The aim of this study is to compare the clinical efficacy and radiological outcomes between UBE and PELD in the treatment of LDH. Methods A retrospective analysis was conducted on 108 patients with LDH treated with spinal endoscopy in our hospital from January 2021 to July 2023. …”
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Association of Serum Uric Acid With Relative Muscle Loss: A US Population–Based Cross‐Sectional Study by Fuquan Wang, Lin Wen, Xiaopeng Guo, Weiwei Wang, Yanyan Cao, Guofeng Zhou, Jun Wang, Chuansheng Zheng

“…We sought to investigate the association of SUA levels with relative muscle loss in the National Health and Nutrition Examination Survey (NHANES) 2011–2018. Methods Relative muscle loss was defined by the Foundation for the National Institutes of Health (FNIH) as characterized by appendicular lean mass (ALM) adjusted by BMI (ALM/BMI) < 0.512 for women and < 0.789 for men. …”
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Effectiveness Of The Core Activation And Rehabilitation Exercises For Knee Osteoarthritis - Program (CARE -KOA©) Among Patients Diagnosed With Knee Osteoarthritis. [version 4; peer... by Saurabh Mehta, Ajit R. Mahale, Dias Tina Thomas, Prajwal Prabhudev Mane, Atmananda S Hegde, Charu Eapen

“…Recent research highlights the role of kinetic chain and core muscle involvement in disease progression, yet evidence for structured core activation protocols such as CARE-KOA© remains limited.This study addresses this gap by evaluating the effectiveness of CARE-KOA©, which specifically targets proximal stability and biomechanical deficits in KOA, aiming to enhance pain, function, and core endurance beyond conventional approaches. Methods This prospective single-group pre-post study assessed the effect of a Participants underwent a 4-week CARE-KOA© regimen (12 supervised sessions, each including a 10-minute warm-up and core-focused exercises). …”
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Midterm Outcomes of Transfibular Total Ankle Arthroplasty: Clinical and Radiographic Analysis of 130 Cases with Minimum 5-Year Follow-Up by Jonathan Day MD, Amanda N. Fletcher MD, MSc, Morgan Motsay BS, Maggie K. Manchester BS, Mark Arthur MD, Zijun Zhang PhD, MD, Lew C. Schon MD

“…Here we present the largest midterm study to date by a single-surgeon, and analyze the survivorship, clinical, and radiographic outcomes of the transfibular TAA at a minimum of 5-years follow-up. Methods: Retrospective review was performed on prospectively followed patients who underwent primary transfibular TAA by a single surgeon from October 2012 to December 2018. …”
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Clinical efficacy of one-hole split endoscopy vs. unilateral biportal endoscopy for the treatment of single-segment lumbar spinal stenosis: a retrospective study with 2-year follow... by Peidong Qing, Wenlong Guo, Shiming Xie, Shengxin Zhao, Liqiang Cui, Mingfan Li, Shuangquan Gong, Youpeng Hu

“…This study aimed to compare the long-term efficacy of OSE and unilateral biportal endoscopy (UBE) in LSS treatment.MethodsThe clinical data of 77 patients diagnosed with LSS at our hospital between January 2020 and March 2022 were retrospectively analyzed. …”
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Validity and Feasibility of the Seated Medicine Ball Throw and Unilateral Shot-Put Tests in Assessing Upper Extremity Function in Rotator-Cuff-Related Shoulder Pain by Michal Linkovski, Jeremy Lewis, Hilla Sarig Bahat

“…This study aimed to evaluate the feasibility, discriminative validity, and convergent validity of these tests in individuals with RCRSP. <b>Methods:</b> This cross-sectional study included 64 participants: 30 with RCRSP and 34 asymptomatic controls. …”
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Comparative Efficacy of Different Exercise Therapies for Cardiorespiratory Fitness in Breast Cancer Survivors: A Systematic Review and Bayesian Network Meta-analysis by Xue Zhou, Yao Yang, Liwen Zhai, Jianing Gan, Conghui Li, Yi Zhu

“…Therefore, this network meta-analysis (NMA) aims to compare the effects of different exercise therapies and explore the possible optimal choice to improve CRF in breast cancer survivors. Methods A systematic search was conducted in EMBASE, the Cochrane Library, PubMed, Web of Science, and CINAHL to identify relevant randomized controlled trials (RCTs). …”
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Quantitative analysis of retinal vascular parameters changes in school-age children with refractive error using artificial intelligence by Linlin Liu, Lijie Zhong, Linggeng Zeng, Fang Liu, Xinghui Yu, Lianfeng Xie, Shuxiang Tan, Shuang Zhang, Yi-Ping Jiang

“…AimTo quantitatively analyze the relationship between spherical equivalent refraction (SER) and retinal vascular changes in school-age children with refractive error by applying fundus photography combined with artificial intelligence (AI) technology and explore the structural changes in retinal vasculature in these children.MethodsWe conducted a retrospective case–control study, collecting data on 113 cases involving 226 eyes of schoolchildren aged 6–12 years who attended outpatient clinics in our hospital between October 2021 and May 2022. …”
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Migraine and its childhood equivalents by P. V. Zhmyleva, G. R. Tabeeva

“…In addition to pain manifestations, episodic syndromes are also found in children, which often lack cephalgic manifestations and are difficult to verify in clinical practice.Objective: to determine the characteristics of the migraine and episodic syndromes associated with migraine in children of different age groups.Material and methods. The study included 250 children complaining of headaches (166 girls and 84 boys aged 5 to 18 years, mean age 13 years). …”
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Performance of OncoE6TM Cervical Test in detecting cervical precancer lesions in HIV-positive women attending an HIV clinic in Bujumbura, Burundi: a cross-sectional study by Zacharie Ndizeye, Sonia Menon, Jean-Pierre Van Geertruyden, Catherine Sauvaget, Y Jacquemyn, John-Paul Bogers, Ina Benoy, Davy Vanden Broeck

“…To this end, we evaluated the clinical performance of the OncoE6 Cervical Test in detecting cervical intraepithelial neoplasia (CIN) among HIV-infected women in Bujumbura, Burundi.Methods From June to December 2017, a cross-sectional study was conducted in 680 HIV-positive women at the University Hospital. …”
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Results from AD-HEARING (ADherence to and adjustment of HEARING aids in clinical routine care as preventive dementia strategy): a prospective 6-month follow-up study on cognition a... by Michael Belz, Sebastian Gmeinwieser, Mona Abdel-Hamid, Mona Abdel-Hamid, Robert Kühler, Jenny Blum, Philipp Hessmann, Nicola Strenzke, Claudia Bartels

“…Hearing aid use might reduce this risk by preserving cognitive and psychological functions.ObjectiveThis study aims to investigate the influence of ARHL and hearing aid use on cognition and different aspects of psychological well-being.MethodsDuring 05/2021 and 05/2023, 31 subjects with audiometrically confirmed ARHL were included and 28 underwent follow-up 6 months later (final analysis sample). …”
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Arthroscopic Margin Convergence Repair Without Suture Anchors Improves Clinical Outcomes for Full- and Partial-Thickness Rotator Cuff Tears by S. Ali Ghasemi, M.D., Benjamin Murray, D.O., Adam Lencer, D.O., Emily Schueppert, D.O., James Raphael, M.D., Craig Morgan, M.D., Arthur Bartolozzi, M.D.

“…Purpose: To evaluate the clinical outcome scores of an arthroscopic margin convergence technique without the use of suture anchors to repair different types of rotator cuff tears and to determine whether the type or extent of the tear has an effect on clinical outcome scores after this procedure. Methods: Patients receiving arthroscopic margin convergence repair without suture anchors for rotator cuff tears from 2013 to 2018 were retrospectively analyzed. …”
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The effectiveness of the REAL™, a school-based, virtual reality-integrated social emotional learning intervention to promote mental health for early Malaysian adolescents by Aimi Nur Athira Putri Baharuddin, Nik Ruzyanei Nik Jaafar, Normala Ibrahim, Abdul Rahman Ahmad Badayai, Hajar Mohd Salleh Sahimi, Nurul Ain Mohamad Kamal, Nur Husna Ismail, Ely Salwana, Mohd Pilus Abdullah, Mohd ‘Ammar Ihsan Ahmad Zamzuri

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Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Objective: To prospectively evaluate the long-term effects of orthognathic surgery on masticatory function in individuals with repaired complete cleft lip and palate and to compare the results with a control group. Material and methods: A total of 40 individuals were prospectively analyzed before (PRE-ORTHOG) and approximately 12 months after orthognathic surgery (POST-ORTHOG). …”
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The assessment of dupilumab in children with moderate-to-severe asthma and comorbid type 2 inflammatory diseases by Tingting Shi, Shuning Wu, Rongshan Chen, Yaping Xie, Genquan Yin, Chunhui He, Cuiping Liang, Gen Lu

“…Abstract Background Dupilumab inhibiting the signaling of interleukin(IL)-4 and IL-13 was recommended for the treatment of severe asthma in children ≥ 6 years old according to the Global Initiative for Asthma (GINA,2024).This study aimed to analyse the efficacy and safety of dupilumab in paediatric patients with moderate-to-severe asthma and comorbid type 2 inflammatory disease in a real-world population. Methods We evaluated the medical records of paediatric patients with moderate-to-severe asthma and comorbid type 2 inflammatory diseases, such as atopic dermatitis (AD) and allergic rhinitis (AR), receiving dupilumab treatment. …”
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Double-level knee valgization osteotomy has high survivorship and a low complication rate in a single-center series of 58 cases with a mean clinical follow-up of 10 years by Ahmed Mabrouk, Michael Risebury, Sam Yasen

“…This study reports on the early to midterm outcomes, both clinical and radiological, of valgization DLO for varus knees and the first study to report the 10-year survivorship of this procedure. Methods A retrospective review of a prospectively maintained single-center database of 1170 knee osteotomies was undertaken. …”
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