Anterior lumbar interbody fusion with a novel osteoinductive allograft – Mid-term clinical and radiographic outcomes by Charlie R. Faulks, Dean T. Biddau, Michael D. Selby, Ralph J. Mobbs, Gregory M. Malham

“…We aimed to evaluate the clinical and radiographic outcomes of patients who underwent ALIF with a novel osteoinductive demineralised bone allograft (DBA) due to the paucity of peer reviewed literature. Methods: Includes 112 consecutive patients from 3 senior spine surgeons (multi-centre) undergoing stand-alone ALIF with osteoinductive DBA (Allovance® Crunch Plus) between January 1, 2019 and January 1, 2022. …”
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Anterior cervical discectomy and fusion in treating acute myelopathy caused by Brucella cervical spondylitis: a case series by Long Chen, Tao Zhang, Xing-yu Chen, Yi-zhe Wang, Xing-guo Tan, Da-shuai Huang, Yan-peng Lu, Song-kai Li

“…This study aims to begin to investigate the clinical characteristics of acute cervical myelitis caused by Brucella infection and to evaluate the profile of clinical benefit of anterior cervical discectomy and fusion (ACDF) for this condition.Methods This retrospective case series included 6 patients who underwent surgical treatment for acute cervical spinal cord impairment due to Brucella infection at our institution between January 1, 2013, and January 1, 2023. …”
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Multimodal Analgesia Approach in Acute Low Back Pain Management: A Phase III Study of a Novel Analgesic Combination of Etoricoxib/Tramadol by Miguel A. Zuqui-Ramírez, Victor M. Belalcazar-López, Adelfia Urenda-Quezada, Alejandro González-Rebatu y González, José G. Sander-Padilla, Laura A. Lugo-Sánchez, Ileana C. Rodríguez-Vázquez, Kevin F. Rios-Brito, María M. Arguedas-Núñez, Emmanuel Canales-Vázquez, Jorge González-Canudas

“…This study evaluated the efficacy and safety between two fixed-dose combinations (FDC): etoricoxib/tramadol compared to paracetamol/tramadol for the management of acute low back pain (LBP) in a 7-day treatment. Methods We conducted a phase IIIb, prospective, randomized, and multicenter study in patients with acute LBP treated with etoricoxib 90 mg/tramadol 50 mg (one packet of granules diluted in 100 ml of water, once a day [QD], for 7 days) or paracetamol 975 mg/tramadol 112.5 mg (one tablet of 325 mg/37.5 mg, three times a day [TID], for 7 days) to assess the efficacy (in terms of pain and disability improvement) and safety. …”
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Neuroprotective effects of healthful plant-based diets on retinal structure: insights from a large cohort by Qian Zhu, Xiaoxin Liu, Yuan Qu, Yan Jiang, Xinyi Liu, Yu Xiao, Kangjia Lv, Yupeng Xu, Kun Liu

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Ophiopogon japonicus (L. f.) Ker Gawl. extract treats dry eye disease via anti-inflammatory, antioxidant, and goblet cell-stimulating effects by Guoliang Li, Rui Feng, Jiayi Yu, Boliang Li, Yanni Luo, Hongyi Luo, Cheng Zhang, Guanghong Zhang, Jianglong Li, Chao Qu

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Relative peripheral refractive errors in Chinese children with myopic anisometropia by Yu-Ting Tong, Yu-Qin Du, Shan-Shan Ge, Li Chen, Xiao-Qi Ma, Yu-Juan Guo, Yue-Hua Zhou

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Association of serum potassium time in target range with cardiovascular outcomes in patients with HFpEF by Yu Liu, Jianping Bin, Yating Tang, Yanmei Chen, Wenlong Xu, Yuegang Wang, Zhiwen Xiao, Yingxuan Li, Xingqiao Chen, Fengling He, Haoxiang Huang, Chuling Li, Jiajun Zhou

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Comorbidity health pathways in heart failure patients: A sequences-of-regressions analysis using cross-sectional data from 10,575 patients in the Swedish Heart Failure Registry. by Claire A Lawson, Ivonne Solis-Trapala, Ulf Dahlstrom, Mamas Mamas, Tiny Jaarsma, Umesh T Kadam, Anna Stromberg

“…The following hypotheses were tested: (i) comorbidities are associated with more severe symptoms and functional limitations and subsequently worse patient-rated health in HF, and (ii) these patterns of association differ among selected comorbidities.<h4>Methods and findings</h4>The Swedish Heart Failure Registry (SHFR) is a national population-based register of HF patients admitted to >85% of hospitals in Sweden or attending outpatient clinics. …”
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Vibration Energy Color Doppler Imaging (VECDI) in Evaluating the Effect of Screw Fixation on Sacroiliac Joint Stiffness: A Prospective Pilot Study by Caleb Gottlich, Thomas Githens, Alex Drusch, Neil Jain, Cyrus Caroom, Phillip S. Sizer

“…Questions/purposes This pilot study examined SIJ stiffness in patients with intact sacroiliac screw fixation to: (1) establish vibration energy color Doppler imaging (VECDI) SIJ intra-rater reliability; (2) measure SIJ stiffness in subjects following surgical fixation using VECDI; (3) compare stiffness data between post-surgical and healthy control subjects; (4) evaluate the relationship between stiffness data and pain and disability scores. Methods 13 reliability and 19 experimental subjects were tested using VECDI. …”
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A prospective randomized controlled trial comparing biphasic cartilage repair implant with microfracture in small chondral lesions of knee: findings at five-year-follow-up by Yao-Yi Kuo, Si-Qi Chiu, Wen-Pei Chang, Chih-Yu Chen, Chih-Hwa Chen, Chen-Kun Liaw, Cheng-Aun Tan, Pei-Wei Weng

“…This study aimed to compare the clinical and radiological outcomes of Biphasic Cartilage Repair Implant (BiCRI) and microfracture treatments for knee cartilage defects. Methods This randomized controlled clinical trial enrolled patients with symptomatic knee chondral lesions smaller than 3 cm2. …”
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Impact of cessation of caffeine citrate therapy on intermittent hypoxemia patterns among preterm infants born before 34 weeks by Peter Kipkurui Mashep, Roseline Ochieng, Jesse Coleman, Mary Waiyego, Amy Sarah Ginsburg, Dorothy Chomba, Morris Ogero Ondieki, Grace Irimu, William M. Macharia, J. Mark Ansermino

“…Standard patient monitors cannot detect IH events due to long averaging times.ObjectiveDescribe change in patterns of IH events in preterms &lt;34 weeks before and after cessation of caffeine citrate and factors associated.MethodsInterrupted time series study design. Data was collected from 1 December 2022 to 30 June 2023. …”
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Microcirculation Disorders in Patients with Severe COVID-19 by E. E. Ladozhskaya-Gapeenko, K. N. Khrapov, Yu. S. Polushin, I. V. Shlyk, N. N. Petrishchev, I. V. Vartanova

“…The presence of avascular zones,  the number of capillaries in the visualized field with circulating aggregates in the lumen, and the shape of capillaries were taken into account.  …”
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Association of self-efficacy, risk attitudes, and time preferences with health-related quality of life and functioning after total hip or knee replacement – Results of the MobilE-T... by Sebastian Fuchs, Lars Schwettmann, Benedict Katzenberger, Alexander Paulus, Boris Michael Holzapfel, Johanna Theresia Biebl, Martin Weigl

“…This study explored the associations between self-efficacy, willingness to take risk regarding health (H-WTTR), and future orientation, and the 3-month course of health-related quality of life (HRQoL) and OA-specific health status. Methods As part of the prospective and observational MobilE-TRA 2 cohort study, 147 patients aged 60 years and older were assessed by self-administered questionnaires before and three months after THR/TKR at a single German hospital. …”
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Effects of the subanesthetic dose of esketamine on postoperative sleep quality in patients undergoing modified radical mastectomy: a randomized, double-blind controlled trial by Ying Chen, Junchen He, Rong Huang, Zhuoqi Pan, Min Zhong, Wenxuan Zhang

“…The purpose of this study was to observe the effects of intraoperative subanesthetic dose of esketamine on the sleep of patients undergoing modified radical mastectomy.MethodsThis randomized, double-blind, controlled trial enrolled 145 female patients, who were randomly assigned to either the esketamine group (Group E, n = 72) or the control group (Group C, n = 73). …”
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Mapping the Epidemiologic Features of Endotracheal Tube ObstructionTake-Home Points by Vimal Bhardwaj, MD, FNB(Critical Care), EDIC, Abhishek Samprathi, MD, DrNB, EDIC, Manu M.K. Varma, MD, DM, Kingshuk Saha, MSc, Ross Prager, MD, John Basmaji, MD, Nicolas Orozco, MD, Srirang Ramamoorthy, MSc, Jose Chacko, MD, EDIC, Arjun Alva, MD

“…Research Question: What are the incidence, risk factors, and associated clinical and ventilator factors of ETBs in ventilated patients in the ICU? Study Design and Methods: We assessed 369 endotracheal tubes (ETTs) of mechanically ventilated patients after extubation. …”
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Clinical application of kangfuxin liquid combined with metronidazole after impacted mandibular third molar extraction by SHOU Wangjin, CHEN Guoyong

“…[Objective:] To evaluate the efficacy of kangfuxin liquid combined with metronidazole in patients with impacted mandibular third molar (IMTM) extraction. [Methods:] A total of 100 patients who underwent IMTM extraction surgery at our hospital from January 2022 to May 2023 were enrolled. …”
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Efficacy of External Beam Radiotherapy with Concurrent Capecitabine versus Radiotherapy alone for the Treatment of Painful Bone Metastasis in Primary Breast Cancer Patients: A Pros... by Lucy Pattanayak, Tapan Kumar Sahoo, Manoranjan Meher, Pragyna Paramita Das, Tapas Kumar Dash

“…Aim: To compare the safety and efficacy of EBRT with concurrent capecitabine against EBRT alone in pain control of painful bone metastasis. Materials and Methods: This prospective interventional study was conducted in the Department of Radiation Oncology at Acharya Harihar Postgraduate Institute of Cancer, Cuttack, Odisha, India from September 2022 to March 2024. …”
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Clinical efficacy analysis of extrapedicular unilateral percutaneous vertebroplasty via the upper edge of the transverse process for lumbar osteoporotic vertebral compression fract... by Junru Zheng, Haopeng Luan, Ying He, Lei Hong, Pengyuan Han, Xiaonan Wang, Xing Wang, Qiaojuan Wang, Qisong Shang

“…Abstract Objective To investigate the clinical effect of vertebroplasty through unilateral upper edge of transverse process in the treatment of lumbar osteoporotic vertebral compression fracture (OVCF), and to explore the surgical indications and operation points of this technique. Methods Ninety patients with osteoporotic vertebral compression fractures of the lumbar spine treated in our hospital from June 2020 to June 2021 were retrospectively analyzed and divided into the experimental group and the control group for vertebroplasty according to the principle of randomization; the experimental group was treated with a lateral pedicle approach through the upper edge of the unilateral transverse process, and the control group was treated with a unilateral pedicle approach. …”
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Status of Digital Health Technology Adoption in 5 Vietnamese Hospitals: Cross-Sectional Assessment by Duc Minh Tran, Nguyen Thanh Dung, Chau Minh Duc, Huynh Ngoc Hon, Le Minh Khoi, Nguyen Phuc Hau, Duong Thi Thu Huyen, Huynh Thi Le Thu, Tran Van Duc, Lam Minh Yen, C Louise Thwaites, Chris Paton

“…ObjectiveWe aimed to explore the current digital maturity in 5 Vietnamese public hospitals to understand their readiness in implementing new DHTs. MethodsWe assessed the adoption of some key DHTs and infrastructure in 5 top-tier public hospitals in Vietnam using a questionnaire adapted from the Vietnam Health Information Technology (HIT) Maturity Model. …”
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Comparison of Gabapentin and Placebo as Pre-emptive Analgesic Agent for Postoperative Analgesia in Patients Undergoing Elective Abdominal Hysterectomy under Spinal Anaesthesia: A R... by Divyang Satishkumar Sutaria, Anjali Tripathi, Vishwa Rameshbhai Patel, Chandrika V Bhut

“…Aim: The purpose of the study was to assess the efficacy of gabapentin and placebo in providing pre-emptive analgesia for postoperative pain management among patients undergoing elective abdominal hysterectomy under spinal anesthesia. Materials and Methods: A single-blind randomised controlled trial was conducted among patients undergoing elective abdominal hysterectomy who had American Society of Anesthesiologists (ASA) physical status I-II. …”
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