Comparison of intravitreal anti-VEGF agents and oral carbonic anhydrase inhibitors in the treatment of cystoid macular edema secondary to retinitis pigmentosa by Jia Liang, Xueping Wu, Lu Chen, Lujia Feng, Xiangqing Hei, Yingying Diao, Yuke Ji, Huiyan Zheng, Zhenhua Zou, Dong Fang, Shaochong Zhang

“…PurposeTo compare the efficacy of intravitreal antivascular endothelial growth factor (anti-VEGF) agents with oral carbonic anhydrase inhibitors (CAIs) in treating cystoid macular edema (CME) secondary to retinitis pigmentosa (RP).MethodsThis retrospective study analyzed 98 patients (98 eyes) with RP-CME: 47 (48.0%) received intravitreal anti-VEGF agents (Ranibizumab or Bevacizumab) and 51 (52.0%) were treated with oral CAIs (methazolamide 50 mg/day or acetazolamide 500 mg/day). …”
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Age-Related Variations in Anterior, Posterior, and Total Corneal Astigmatism by Pothikamjorn T, Surawatsatien N, Ueathaweephol S, Somkijrungroj T

“…However, age-related changes and sex-based differences in PCA and TCA remain inconclusive due to limited sample sizes in previous studies.Methods: We conducted a cross-sectional observational study using biometric measurements obtained with the IOLMaster 700. …”
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Advancing Nanomedicine Through Electron Microscopy: Insights Into Nanoparticle Cellular Interactions and Biomedical Applications by Akhtar S, Zuhair F

“…However, challenges like sample preparation and artifacts persist, with rapid freezing methods, such as plunge-freezing particularly, high-pressure freezing, proving effective in preserving native cellular structures. …”
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PLS-DA model for accurate identification of Chinese cabbage leaf color based on multispectral imaging by Ziwei Xie, Jinghui Yan, Hao Liang, Xiaonan Yue, Xiangjie Su, Huixin Wei, Yin Lu, Xiaofei Fan, Wei Ma, Xiaomeng Zhang, Xiaoxue Sun, Dongfang Zhang, Jingrui Li, Jianjun Zhao, Mengyang Liu

“…In this study, we constructed a partial least squares discriminant analysis (PLS-DA) leaf color identification model and compared four classification methods for leaf color, namely red, green, and blue (RGB) channels, hue, saturation, and lightness (HSL) color space, multi-spectrum and data-fusion. …”
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The Efficacy of Oral Dexamethasone in the Management of Symptomatic Irreversible Pulpitis Without Pulpotomy: A Non-Randomized Clinical Trial by Sara Chehab, Roula Abiad, Lara Nasr, Hala Sacre, Pascale Salameh, Reem Chamseddine, Romy Zouein, Louis Hardan, Naji Kharouf, Rim Bourgi, Roula El Hachem

“…The purpose of this clinical trial was to evaluate the effectiveness of an inferior alveolar nerve block (IANB) injection followed by oral dexamethasone administration in reducing the pain associated with symptomatic irreversible pulpitis (SIP) in mandibular molars, without performing conventional pulpotomy. Methods: A sample of 80 subjects suffering from acute pain due to SIP on a mandibular molar were assigned to the dexamethasone group, who received an IANB injection followed by one oral dose of 4 mg of dexamethasone during the emergency visit followed by one dose of 4 mg after 8 h, or the control group, who received a conventional pulpotomy. …”
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Relationship between cognitive impairments and psychopathological symptoms in female schizophrenia subsequent to 8 weeks treatment with antipsychotic drugs by Shuzhan Gao, Qing Xu, Yanlin Han, Jing Jiang, Fan Wu, Ting Peng, Chenxi Ling, Sulin Ni, Rongrong Zhang, Yidan Ming, Xuzhen Liu, Xijia Xu

“…Further exploration of the characteristics of female schizophrenia patients can offer valuable sex-related considerations for clinicians in diagnosis and interventions. Methods Our study involved 94 female patients with drug-naïve or drug-withdrawal schizophrenia who received antipsychotic drug for 8 weeks, along with 71 age-matched female healthy controls. …”
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Vitamin D insufficiency and sleep disturbances in children with ADHD: a case-control study by Panpan Zhang, Panpan Zhang, Yang Liu, Yang Liu, Yan Ma, Yan Ma, Tingting Zhao, Tingting Zhao, Chan Zhang, Chan Zhang, Hao Sun, Hao Sun

“…Regrettably, no studies have looked at whether vitamin D insufficiency exacerbates sleep problems in ADHD children and further affects ADHD symptoms.ObjectiveThis study aimed to examine whether vitamin D insufficiency exacerbates sleep problems and ADHD symptoms in children aged 6–14 years.MethodsThis is a case-control study, 260 ADHD children (aged 6-14 years) were enrolled in, of whom 95 had vitamin D insufficiency and 165 had sufficiency. …”
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Increased concentration of tumour necrosis factor alpha in the plasma of glaucoma patients by Trenkić Marija, Jevtović-Stoimenov Tatjana, Bašić Jelena, Vasilijević Jelena, Ristić Dragana, Trenkić Milan, Veselinović Aleksandar, Cvetanović Marija

“…The aim of the study was to determine concentrations of tumor necrosis factor (TNF)-α in the plasma of patients with OAG and subjects without glaucoma and examine the correlation between the TNF-α concentration in plasma in glaucoma patients and specific clinical parameters. Methods. The study included 87 participants (87 eyes) divided into three groups: 35 subjects (35 eyes) with primary OAG (POAG) with elevated intraocular pressure (IOP) – hypertension glaucoma (HTG) (POAG-HTG), 23 subjects (23 eyes) with pseudoexfoliative OAG (XFG), and 29 subjects in the control group (healthy subjects) matched with the patient groups in terms of age and gender. …”
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Expression and clinical significance of FANCI gene in pan-cancer: a comprehensive analysis based on multi-omics data by Yunzheng Zhao, Yunzheng Zhao, Qingyu Li, Qingyu Li, Jiajun Li, Jiajun Li, YiFeng Cui, YiFeng Cui, Zhaoyang Lu, Zhaoyang Lu

“…This investigation seeks to clarify the expression profiles, prognostic relevance, and diagnostic capabilities of FANCI across multiple malignancies, along with its links to immune cell infiltration, genetic alterations, protein-protein interactions, and functional roles.MethodsBy utilizing data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx) databases, we conducted a comprehensive analysis of FANCI mRNA expression using R software and visualized the results with the ggplot2 package. …”
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Conservative treatment versus hip arthroscopy in patients with femoroacetabular impingement: a multilevel meta-analysis of randomized controlled trials by Nikolai Ramadanov, Jonathan Lettner, Maximilian Voss, Robert Hable, Robert Prill, Dobromir Dimitrov, Roland Becker

“…The aim of this multilevel meta-analysis of randomized controlled trials (RCTs) was to evaluate the outcomes of FAI patients treated conservatively compared with those treated with hip arthroscopy (HAS). Methods: A systematic literature search of PubMed, CENTRAL of the Cochrane Library, Epistemonikos, and Embase databases was conducted up to 30 June 2024. …”
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Deep Learning and Edge Computing in Agriculture: A Comprehensive Review of Recent Trends and Innovations by Apri Junaidi, Siti Zaiton Mohd Hashim, Mohd Shahizan Bin Othman, Mohd Murtadha Bin Mohamad, Hitham Alhussian, Said Jadid Abdulkadir, Maged Nasser, Yunusa Adamu Bena

“…Traditional inspection methods are labor-intensive and error-prone, highlighting the need for automated, intelligent solutions. …”
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Directly anterior approach for total hip arthroplasty with an acetabular structural bone graft for developmental dysplasia of the hip (Crowe III and IV): a concise 5-year follow-up... by Lijia Pei, Ben Liu, Yifan Wu, Yuanhang Wang, Wenhao Sun, Wenju Chang, Xinshe Zhou

“…Abstract Background This study evaluated the results of total hip arthroplasty (THA) via the direct anterior approach (DAA) in the lateral decubitus position combined with acetabular reconstruction via a bulk autograft for patients with developmental dysplasia of the hip (Crowe III and IV). Patients and methods A retrospective study was conducted to analyse 16 patients (16 hips) with Crowe type III and IV developmental dysplasia of the hip (DDH) who underwent THA from June 2016 to July 2021. …”
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Clinical profile, associated events and safety of vericiguat in a real‐world cohort: The VERITA study by Mario Galván Ruiz, Miguel Fernández de Sanmamed Girón, María delVal Groba Marco, Lorena Rojo Jorge, Claudia Peña Saavedra, Elvira Martín Bou, Rubén Andrade Guerra, Eduardo Caballero Dorta, Antonio García Quintana

“…Abstract Aims The aim of this study was to determine the clinical profile, associated events and safety of vericiguat in a real‐world cohort of patients with heart failure with reduced ejection fraction (HFrEF). Methods This study is a prospective and observational cohort study of patients with HFrEF and recent HF worsening episodes requiring intravenous therapy who initiated vericiguat in an HF outpatient clinic. …”
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Surgical long-term outcomes of Hirschsprung Disease in the Democratic Republic of Congo: a case series of 31 patients in a resource-limited setting by Fabrice Gulimwentuga Cikomola, Arsene Daniel Nyalundja, Alliance Wani Bisimwa, Bijoux Safi Matabaro, Franck Masumbuko Mukamba, Costa Musilimu Sudi, Paul Budema Munguakonkwa, Leon-Emmanuel Mukengeshayi Mubenga, Kinja Nyamugabo, Désiré Munyali Alumeti, Théophile Kabesha, Marc Miserez, Dieudonné Mushengezi Sengeyi

“…We aimed at assessing the long-term follow-up outcomes following an innovate resection approach in South Kivu, eastern DRC. Methods In this case series, the authors elucidate the admissions for HD spanning from 2016 to 2021 at a Pediatric Surgical Center in the DRC. …”
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Association between triglyceride–glucose index and mortality in critically ill patients with atrial fibrillation: a retrospective cohort study by Rong Ding, Erjing Cheng, Miao Wei, Liya Pan, Lu Ye, Yi Han, Xuan Zhang, Chao Xue, Jiannan Gong, Hui Zhao

“…This study aimed to investigate the association between the TyG index and all-cause mortality in this high-risk population. Methods We identified critically ill patients with AF from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database and categorized them into tertiles based on their TyG index levels. …”
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Radiomics Signature of Aging Myocardium in Cardiac Photon-Counting Computed Tomography by Alexander Hertel, Mustafa Kuru, Johann S. Rink, Florian Haag, Abhinay Vellala, Theano Papavassiliu, Matthias F. Froelich, Stefan O. Schoenberg, Isabelle Ayx

“…Detecting structural changes in aging left-ventricular myocardium may help predict cardiovascular risk. <b>Methods</b>: In this retrospective, single-center, IRB-approved study, 90 patients underwent ECG-gated contrast-enhanced cardiac CT using dual-source PCCT (NAEOTOM Alpha, Siemens). …”
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Comparative Genomics of Rhamnolipid Synthesis and Monoaromatic Hydrocarbon Tolerance Genes in Environmental Pseudomonas aeruginosa strains [version 2; peer review: 2 approved] by Sandro B. Martel-Torres, Camila Castillo-Vilcahuaman, ROGER A. PALOMINO HUARCAYA, Susana M. Gutiérrez Moreno, Fernando A. Merino Rafael

“…This study aimed to investigate the rhl and mla systems in six strains isolated from hydrocarbon-contaminated sites in Peru. Methods Six Pseudomonas aeruginosa strains were evaluated in this study. …”
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Application of hyperbaric oxygen therapy in femoral head necrosis: a systematic review and meta-analysis by Yangbin Cao, Peiyuan Tang, Han Tan, Wenbo Ma, Hua Chai, Bin Lin, Ying Zhu, Wenfeng Xiao, Ting Wen, Jun Zhang, Yusheng Li, Shuguang Liu

“…Purpose: To evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) in the treatment of osteonecrosis of the femoral head (ONFH). Methods: Search for term systems related to ONFH and HBOT in PubMed, Cochrane Library, Embase and Web of Science databases. …”
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Risk factors of obstructive sleep apnea syndrome in children by Zhifei Xu, Yunxiao Wu, Jun Tai, Guoshuang Feng, Wentong Ge, Li Zheng, Zhe Zhou, Xin Ni

“…Our objective is to identify risk factors of OSAS in children in a clinical setting. Methods Children between 2 and 15 years of age exhibiting snoring symptoms who visited the sleep center for polysomnography (PSG) were enrolled. …”
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Effect of herbal medicine Bojungikgi-tang on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial by Boram Lee, Mi Mi Ko, You Mee Ahn, Hyo-Ju Park, So Young Jung, Hyun-A Jung, Hesol Lee, Pyung-Wha Kim, Yujin Choi, Kyungsun Han, Sarah Shin, Jeeyoun Jung

“…This study aimed to evaluate the effects and safety of BJT in anorexic patients with AD and to investigate its therapeutic mechanism through gut microbiome analysis.MethodsThe trial included 26 adults with AD and anorexia, randomized (1:1) into BJT or waiting list groups for 12 weeks, including 8 weeks of treatment and 4 weeks of follow-up. …”
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