Efficacy of combining posterior scleral contraction and intravitreal C3F8 injection in high myopia with macular hole retinal detachment by Si Chen, Jie Ye, Qin-Tuo Pan, Fang Huang, Lin-Yan Zheng, Hui-Fang Ye, Yan-Feng Su, Yan Li, Shuang-Qian Zhu

“…AIM: To evaluate the efficacy and safety of combining posterior scleral contraction (PSC) with intravitreal perfluoropropane (C3F8) injection in high myopia with macular hole retinal detachment (MHRD). METHODS: A total of 22 participants (22 eyes) with high myopia [axial length (AL)≥26.5 mm] and MHRD who underwent PSC combined with intravitreal C3F8 injection, with at least 6mo of follow-up were retrospectively recruited. …”
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Silver diamine fluoride alters microbial communities in subsurface dentinWhy Is This Important? by Rosalyn M. Sulyanto, DMD, MS, Clifford J. Beall, MS, PhD, Martin T. Berger, DMD, Christopher P. Goodell, DMD, Stephanie Koo, DMD, Fiorella Candamo, DMD, John R. Dickson, MD, PhD, Misun Kang, PhD, Sunita P. Ho, PhD, Man Wai Ng, DDS, MPH, Shahr B. Hashmi, BS, Eugene J. Leys, PhD, Ann L. Griffen, MS, DDS

“…This study examines the mechanisms by which SDF may impact the oral microbiota. Methods: This case-control study uses samples from carious lesions of primary teeth with or without SDF treatment; the authors used microbial viability testing and next-generation sequencing to compare untreated or SDF-treated carious surface biofilm and subsurface carious dentin. …”
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Identification of maize leaf diseases using red, green, blue-based images with convolutional neural network (CNN) and residual network (ResNet50) models by Basani Lammy Nkuna, Khaled Abutaleb, Johannes George Chirima, Solomon W. Newete, Adriaan Johannes van der Walt, Adolph Nyamugama

“…However, it is susceptible to diseases that drastically reduce yields if not controlled. Traditional methods of disease detection of visual inspections are often inaccurate and uncertain. …”
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Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance by Santiago Rodríguez de Córdoba, Andrea Reparaz, Daniel Sanchez, Sheila Pinto, Lucia Juana Lopez, Héctor Martin Merinero, Iria Calvete, Julian Perez-Perez, Sydney S. Jellison, Yuzhou Zhang, Richard J. H. Smith, Inmaculada Moreno, Mercedes Dominguez

“…Current FHAA analysis normally identify free FHAAs that bind surface-bound FH using ELISA techniques. These methods require well-equipped laboratories and qualified staff, and do not measure FH-FHAA complexes, which can make it difficult to correlate titers with clinical outcomes. …”
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Prevalence of eating disorders in South Asian countries: a systematic analysis of Global Burden of Disease (1990–2021) by Prakasini Satapathy, Vijay Kumar, Mahalaqua Nazli Khatib, Lalji Baldaniya, Suhas Ballal, V. Kavitha, Laxmidhar Maharana, Renu Arya, Ganesh Bushi, Muhammed Shabil, Rukshar Syed, Manika Gupta, Sunil Kumar, Sabah Ansar, Sanjit Sah, Diptismita Jena, Edward Mawejje

“…This systematic analysis examines trends and prevalence of Anorexia nervosa (AN) and Bulimia nervosa (BN) using the Global Burden of Disease (GBD) data from 1990 to 2021. Methods This analysis used data from the GBD study on age-standardized prevalence rates (ASPRs) for AN and BN, as well as their total percentage changes (TPCs) from 1990 to 2021. …”
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Extracellular vesicle GABA responds to cadmium stress, and GAD overexpression alleviates cadmium damage in duckweed by Zhanpeng Sun, Zhanpeng Sun, Ziyang Qu, Yuman He, Yujie Han, Yun Xing, Sizheng Liu, Yi Hu, Yumeng Jiang, Yiqi Yu, Yuanyuan Liu, Weibo Sun, Lin Yang

“…While γ-aminobutyric acid (GABA) is known to accumulate rapidly under environmental stress, the real-time dynamics of GABA signaling and its mechanistic link to stress adaptation remain poorly understood.MethodsIn this study, a sensitive GABA biosensor, iGABASnFR, was introduced into plants for the first time to monitor GABA signaling. …”
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Acupuncture for cancer-related insomnia: An evidence mapping by Zining Guo, Liying Wang, Yuting Wang, Wenhao Liu, Yi Zhao, Xiaorong Tang, Run Lin, Zhennan Wu, Shaoyang Cui, Nenggui Xu

“…This study systematically examined research quality and used evidence mapping (EM) to map and present evidence information to identify gaps and inform future research. Methods: Two reviewers searched eight databases from inception to May 2024, screened eligible randomized controlled trials (RCTs), and extracted key characteristics from included studies. …”
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Vibrotactile Stimulation in Lower Extremity Amputation Patients Using a Noninvasive Vibration Device: A Pilot Study by Floris V. Raasveld, MD, Jenna Daddario, PA, Wen-Chih Liu, MD, Dun-Wei Huang, MD, Rachel E. Cross, BA, Karan Amin, BA, Arthur Graham, CP, David Crandell, MD, David Hao, MD, Ian L. Valerio, MD, MS, MBA, FACS, Kyle R. Eberlin, MD

“…This study evaluated the application of a vibrotactile sensory feedback device that aims at enhancing gait and reducing phantom limb pain (PLP) in lower extremity (LE) amputation patients who have undergone targeted muscle reinnervation (TMR). Methods:. Four male LE amputation patients, 25–68 years of age, who underwent primary TMR, were fitted with a vibrotactile device using pressure sensors located on the sole of the prosthesis and a vibrating actuator on the proximal LE. …”
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Multimodal analgesia with parasternal plane block protocol within an enhanced recovery after cardiac surgery program decreases opioid useCentral MessagePerspective by Marc Darras, MD, Clément Schneider, MD, Sandrine Marguerite, MD, Saadé Saadé, MD, Anne-Lise Maechel, MD, Walid Oulehri, MD, Olivier Collange, MD, PhD, Jean-Philippe Mazzucotelli, MD, PhD, Paul-Michel Mertes, MD, PhD, Michel Kindo, MD, PhD

“…Objective: This study investigated the efficacy of a multimodal analgesia (MMA) with an opioid-sparing strategy, incorporating a parasternal plane block (PPB) within a systematic standardized Enhanced Recovery After Surgery (ERAS) program for patients undergoing elective cardiac surgery. Methods: From 2015 to 2021, 3153 patients underwent elective coronary artery bypass grafting and/or valve procedures. …”
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Pharmacopuncture therapy for adhesive capsulitis: A pragmatic randomized controlled pilot study by Doori Kim, Kyoung Sun Park, Sun-A Kim, Ji Yeon Seo, Hyun-Woo Cho, Yoon Jae Lee, Changsop Yang, In-Hyuk Ha, Chang-Hyun Han

“…We compared the effectiveness and safety of pharmacopuncture and physiotherapy for AC. Methods: This pragmatic, randomized, controlled, parallel-group pilot study enrolled patients with limitations of shoulder movement and a numeric rating scale (NRS) score for shoulder pain ≥5 randomized (1:1) to the pharmacopuncture therapy (PPT) and physiotherapy (PT) groups. …”
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Prevalence of the anti-CASPR2 autoantibody in patients with somatic symptom disorder accompanied by medically unexplained pain by Shingo Katayama, Gayatri Nayanar, Takayuki Suga, Motoko Watanabe, Chihiro Takao, Yojiro Umezaki, Hidehiko Takahashi, Akira Toyofuku, Hiroki Shiwaku

“…Thus, the current study aims to investigate the seroprevalence of the anti-CASPR2 autoantibody among patients with SSD accompanied with pain and their associations with disease characteristics. Methods: The serum samples obtained from 264 patients with SSD accompanied with pain and 260 healthy controls were screened for anti-CASPR2 autoantibodies using a cell-based assay. …”
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Development and validation of a diagnostic model for tuberculous meningitis based on laboratory data by Fuyong Liu, Zheng Li, Xuejiao Li, Wei Hong, Yanlin Zhou, Yungang Han, Shuang Xia, Jiao Tan, Yunchang Yang, Shiqi Li, Zhi Li, Wenyi He, Huihui Chen, Pengxiang Li, Yali Wang, Xu Yang, Jingcai Gao, Wei Wang

“…ObjectiveWe developed and validated a diagnostic scoring system for tuberculous meningitis (TBM) using 13 laboratory parameters, comparing tuberculous meningitis (TBM) and non-tuberculous meningitis (non-TBM).MethodsThis study enrolled patients diagnosed with meningitis. …”
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Anesthesiologic management of pregnant women with SARS-COV-2 infection undergoing cesarean delivery by Antonio Coviello, Concetta Posillipo, Ludovica Golino, Carlo De Angelis, Elisabetta Gragnano, Gabriele Saccone, Marilena Ianniello, Gaetano Castellano, Annachiara Marra, Alfredo Maresca, Maria Vargas, Giuseppe Servillo

“…The aim of this study was to evaluate an innovative anesthesiologic opioid-free management protocol in symptomatic pregnant women, with COVID-19 and with oxygen therapy, undergoing cesarean delivery with spinal anesthesia. Methods: With the patient in the sitting position, spinal anesthesia was performed at the L1–L2 level. …”
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Microstructural and functional abnormalities of the locus coeruleus in freezing of gait in Parkinson's disease by Huimin Sun, Caiting Gan, Xingyue Cao, Yongsheng Yuan, Heng Zhang, Chenhui Wan, Jiaxin Shi, Xufeng Wang, Youyong Kong, Tao Feng, Kezhong Zhang

“…This study was to investigate the role of the LC-norepinephrine system in FOG pathophysiology using FW imaging and resting-state functional magnetic resonance imaging. Methods: FW metrics of LC were analyzed in 52 healthy controls, 79 PD patients without FOG (Non-FOG), and 110 PD patients with FOG (48 “Off-period” FOG and 62 “Levodopa unresponsive” FOG). …”
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Relationship between the Degrees of Itch and Serum Lipocalin-2 Levels in Patients with Psoriasis by Norie Aizawa, Yozo Ishiuji, Mitsutoshi Tominaga, Sanae Sakata, Nobuaki Takahashi, Koichi Yanaba, Yoshinori Umezawa, Akihiko Asahina, Utako Kimura, Yasushi Suga, Kenji Takamori, Hidemi Nakagawa

“…This study examined the correlation between serum LCN2 levels and the degrees of itch in patients with psoriasis. Methods. Serum LCN2 concentrations were measured by enzyme-linked immunosorbent assays (ELISA) in patients with psoriasis and AD and in healthy controls. …”
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Patient Outcomes of Thumb Arthroplasty Using a Hybrid Technique for Severe Osteoarthritis by Shiny Chih-Hsuan Wu, MD, Chen-Heng Hsu, MD, Chieh-An Chuang, MD, Sheu Huan, MD, You-Hung Cheng, MD, Cheng-Pang Yang, MD, Joe Chih-Hao Chiu, MD, PhD, Chun-Ying Cheng, MD, Yi-Shen Chan, MD, Alvin Chao-Yu Chen, MD

“…With multiple surgical techniques for thumb carpometacarpal (CMC) arthritis, we propose a hybrid technique combining trapeziectomy with ligament reconstruction and tendon interposition and suture button suspensionplasty to evaluate its statistical significance and clinical relevance. Methods:. We conducted a retrospective study on patients receiving primary surgery of combining trapeziectomy with ligament reconstruction and tendon interposition and suture button suspensionoplasty for advanced osteoarthritis from 2017 to 2023. …”
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Cone mosaic in eyes with varied axial length using adaptive optics scanning laser ophthalmoscopy by Wen-Da Zhou, Li Dong, Han-Xu Shi, Rui-Heng Zhang, Yu-hang Yang, Han-qing Zhao, Yi-Tong Li, Chu-Yao Yu, He-Yan Li, Hao-Tian Wu, Lei Shao, Wen-Bin Wei

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Automated pixel-based quantification of porcine circovirus 2 genome in formalin-fixed, paraffin-embedded tissues using in situ hybridisation by Mònica Sagrera, Mònica Sagrera, Mònica Sagrera, Àlex Cobos, Àlex Cobos, Àlex Cobos, Àlex Cobos, Laura Garza-Moreno, Mónica Pérez, Mónica Pérez, Mónica Pérez, Gema García-Buendía, Gema García-Buendía, Gema García-Buendía, Eva Huerta, Eva Huerta, Eva Huerta, Anna Maria Llorens, Anna Maria Llorens, Anna Maria Llorens, David Espigares, Marina Sibila, Marina Sibila, Marina Sibila, Joaquim Segalés, Joaquim Segalés, Joaquim Segalés

“…In situ hybridisation (ISH) enables the localisation of viral genomes in tissue sections but is traditionally assessed visually, which may introduce subjectivity.MethodsThis study developed an automated pixel classifier to quantify the PCV2 genome using RNAscope® ISH technology. …”
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Advanced Doppler Ultrasound Insights: A Multicenter Prospective Study on Healthy Skin by Priscila Giavedoni, Jorge Romaní, Francisco de Cabo, Francisco Javier García-Martínez, Mónica Quintana-Codina, Esther Roè-Crespo, Irene Fuertes de Vega, Xavier Soria-Gili, Rafael Aguayo-Ortiz, Patricia Garbayo-Salmons, Gonzalo Castillo, David Vidal-Sarró, Jordi Mollet, Laura Serra, Carlos Gonzalez, Emilio López-Trujillo, Miquel Just, Marc Combalia, Sebastian Podlipnik, Josep Malvehy, Ximena Wortsman

“…<b>Objective:</b> This study aimed to evaluate the visible vessels of healthy skin using Doppler ultrasound. <b>Methods:</b> Prospective multicenter study using Doppler ultrasound to analyze healthy skin. …”
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Real-Life Clinical Use and Outcomes of Fusion Imaging-Guided Percutaneous Microwave Ablation of Hepatocellular Carcinoma: Experience from Two Italian Centers by Pierpaolo Biondetti, Francesco Cicchetti, Gaetano Valerio Davide Amato, Velio Ascenti, Niccolò Finardi, Jacopo Tintori, Francesco Ugo Iovino, Carolina Lanza, Salvatore Alessio Angileri, Pierluca Torcia, Anna Maria Ierardi, Giacomo Vignati, Lorenzo Giovanni Monfardini, Gianpaolo Carrafiello

“…This study reports real-life outcomes of USFI-guided microwave ablation (MWA) for HCC in two Italian centers. <b>Materials and Methods:</b> In this multicentric retrospective study, 56 patients with 73 poorly or non-visible HCC nodules underwent USFI-guided percutaneous MWA with no visibility or poor visibility on B-mode US. …”
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