Application of comprehensive geriatric assessment in health management of older patients with grade Ⅲ to Ⅳ mixed hemorrhoids undergoing surgery by Jiang Zhiyuan, Zhong Shibiao, Tang Li, Li Zhen

“…[Objectives] To investigate the application of comprehensive geriatric assessment (CGA) in the health management of older patients with grade Ⅲ to Ⅳmixed hemorrhoids undergoing surgery. [Methods] Sixty older patients with grade Ⅲ to Ⅳ mixed hemorrhoids treated at the Department of Anorectal Surgery at our hospital between January and October 2021 were recruited and randomly assigned to the control group (n=30) and the treatment group (n=30). …”
Get full text

The impact of pyrethroid resistance on the efficacy of insecticide-treated bed nets against African anopheline mosquitoes: systematic review and meta-analysis. by Clare Strode, Sarah Donegan, Paul Garner, Ahmad Ali Enayati, Janet Hemingway

“…We therefore assessed the evidence that resistance is attenuating the effect of ITNs on entomological outcomes.<h4>Methods and findings</h4>We included laboratory and field studies of African malaria vectors that measured resistance at the time of the study and used World Health Organization-recommended impregnation regimens. …”
Get full text

Evaluation of the Effects of Retro-Cavity Preconditioning with or Without Ethylenediaminetetraacetic Acid on Root Surface pH and Dislodgement Resistance of NeoMTA2 and Mineral Trio... by Sedigheh Khedmat, Seyyed Ali Abaee, Hadi Assadian, Antonio Signore, Stefano Benedicenti

“…<b>Background:</b> The aim of this study was to investigate the effects of retro-cavity preconditioning with or without 17% ethylenediaminetetraacetic acid (EDTA) solution on root surface pH as well as dislodgement resistance of NeoMTA2 and MTA Flow retro-fills. <b>Methods:</b> Forty-eight single-rooted human incisors were selected. …”
Get full text

Prokineticin 2 neurons form diverse subpopulations in the suprachiasmatic nucleus and rely on VPAC2-signaling for diurnal rhythmicity by Ida Stangerup, Ida Stangerup, Birgitte Georg, Jens Hannibal, Jens Hannibal

“…Hence, the aim of this study was to characterize PK2 neurons in relations to light-responsiveness and neuropeptidergic markers of the core-shell division.MethodsDouble and triple immunohistochemistry of PK2 together with phenotypical neuropeptide/receptor markers of the core-shell division was performed at zeitgeber time (ZT) 8. …”
Get full text

Development and Validation of a Neonatal Hypothermia Prediction Model for In-Hospital Transport Using Machine Learning Algorithms: A Single-Center Retrospective Study by Zhang W, Gu X, Gu C, Yao L, Zhang Y, Wang K

“…Wenyan Zhang,1,&amp;ast; Xiaoying Gu,1,&amp;ast; Chunjie Gu,1 Lili Yao,1 You Zhang,2 Ke Wang1 1Department of Neonatology, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Information Center, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China&amp;ast;These authors contributed equally to this workCorrespondence: Ke Wang, Email wangkeyfy@126.com You Zhang, Email 122710487@qq.comObjective: This study aims to predict hypothermia during neonatal in-hospital transport using machine learning techniques, identify risk factors, rank their importance, and visualize the results, allowing healthcare providers to rapidly assess the probability of hypothermia risk during transport.Methods: Clinical data of 9,060 neonates transported within a tertiary maternity hospital in Shanghai between January 2023 and June 2024 were collected, including maternal and neonatal data. …”
Get full text

CT radiation dose reduction with tin filter for localisation/characterisation level image quality in PET-CT: a phantom study by Natalie Anne Bebbington, Lone Lange Østergård, Kenneth Boye Christensen, Paw Christian Holdgaard

“…The aim was to determine the level of CT dose reduction permitted with the tin filter in PET-CT, for comparable image quality to the clinical reference standard (CRS) L/C CT images acquired with standard filtration. Materials and methods A whole-body CT phantom was scanned with standard filtration in CRS protocols, using 120 kV with 20mAs-ref for bone L/C (used in 18F-Sodium Fluoride (NaF) PET-CT) and 40mAs-ref for soft tissue L/C (used in 18F-Fluorodeoxyglucose (FDG) PET-CT), followed by tin filter scans at 100 kV (Sn100kV) and 140 kV (Sn140kV) with a range of mAs settings. …”
Get full text

Prevalence and characteristics of transthyretin amyloid cardiomyopathy in hypertrophic cardiomyopathy by Pablo Garcia‐Pavia, Thibaud Damy, Nicolas Piriou, Roberto Barriales‐Villa, Francesco Cappelli, Catherine Bahus, Carmen Munteanu, Denis Keohane, Pablo Mallaina, Perry Elliott, the TTRACK investigators

“…We examined the prevalence and characteristics of transthyretin amyloid cardiomyopathy in older patients with hypertrophic cardiomyopathy of unascertained aetiology. Methods and results TTRACK was a multicentre, non‐interventional, cross‐sectional epidemiologic study funded by Pfizer and conducted in 20 hospitals and medical centres in 11 countries (NCT03842163). …”
Get full text

A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores by Vasanop Vachiramon, Sonphet Chirasuthat, Suphagan Boonpethkaew, Nawara Sakpuwadol, Tanat Yongpisarn, Natthachat Jurairattanaporn

“…This study focuses on the efficacy and safety of combining Onabotulinumtoxin A (OnaBoNT-A) and hyaluronic acid filler (HA filler) to target enlarged facial pores in Asians. Materials and Methods: This study aimed to compare the efficacy and safety of OnaBoNT-A monotherapy in combination with HA filler for the treatment of enlarged facial pores. …”
Get full text

Benchmarking of Large Language Models for the Dental Admission Test by Yu Hou, Jay Patel, Liya Dai, Emily Zhang, Yang Liu, Zaifu Zhan, Pooja Gangwani, Rui Zhang

“…Understanding the capabilities and limitations of these models is critical for determining their suitability in test preparation. Methods: This study evaluated the ability of 16 LLMs, including general-purpose models (e.g., GPT-3.5, GPT-4, GPT-4o, GPT-o1, Google’s Bard, mistral-large, and Claude), domain-specific fine-tuned models (e.g., DentalGPT, MedGPT, and BioGPT), and open-source models (e.g., Llama2-7B, Llama2-13B, Llama2-70B, Llama3-8B, and Llama3-70B), to answer questions from a sample DAT. …”
Get full text

The efficacy and prognosis analysis of short-term spinal cord stimulation in the treatment of zoster-associated pain: a retrospective study by Xiang Wang, Yimin Gao, Jing Yu, Wenqu Yang, Wenjing Zhang, Jianzhong Huo

“…However, in the existing literature, there is a paucity of comprehensive reports elaborating on the risk factors that impact its treatment efficacy.ObjectiveThis study aimed to evaluate the clinical efficacy of stSCS in the treatment of ZAP, and to analyze the risk factors that influence the treatment efficacy.MethodsClinical data of patients diagnosed with ZAP and who underwent stSCS surgery in the Pain Department of Shanxi Bethune Hospital from January 2020 to December 2023 were collected. …”
Get full text

Virtual Reality for the Prevention and Cessation of Nicotine Vaping in Youths: Protocol for a Randomized Controlled Trial by Belinda Borrelli, Daniel Weinstein, Romano Endrighi, Nikki Ling, Kathleen Koval, Lisa M Quintiliani, Kaitlyn Konieczny

“…ObjectiveThis randomized controlled trial aimed to evaluate the feasibility and preliminary efficacy of a virtual reality (VR) intervention for teens that targets both determinants of vaping (eg, mood and stress) and vaping prevention and cessation skills. MethodsThe participants are 150 students attending 1 of 2 racially and ethnically diverse Boston-area high schools. …”
Get full text

Examining Demographic, Geographic, and Temporal Patterns of Melanoma Incidence in Texas From 2000 to 2018: Retrospective Study by Kehe Zhang, Madison M Taylor, Jocelyn Hunyadi, Hung Q Doan, Adewole S Adamson, Paige Miller, Kelly C Nelson, Cici Bauer

“…ObjectiveThis study aims to analyze temporal and spatial trends in melanoma incidence by stage at diagnosis (overall, early, and late) in Texas from 2000 to 2018, focusing on demographic and geographic variations to identify high-risk populations and regions for targeted prevention efforts. MethodsWe used melanoma incidence data from all 254 Texas counties from the Texas Cancer Registry (TCR) from 2000 to 2018, aggregated by county and year. …”
Get full text

Return to sport and patient reported outcomes in athletes participating in martial arts after anterior cruciate ligament reconstruction at mean follow‐up of 12 years by Yunseo Linda Park, Anja M. Wackerle, Brooke Collins, Ehab M. Nazzal, Joseph D. Giusto, Matthew Kolevar, James J. Irrgang, Jonathan D. Hughes, Volker Musahl

“…Abstract Purpose This study aims to assess anterior cruciate ligament reconstruction (ACLR) outcomes and return to pre‐injury sports (RTPS) characteristics in athletes participating in martial arts. Methods Martial arts athletes over the age of 14 years who underwent primary ACLR with a minimum 1‐year follow‐up were eligible for this study. …”
Get full text

Effect of ropivacaine scalp nerve block on postoperative recovery quality after craniotomy by LI Wenjing, LIAO Jinwen, HEI Ziqing, CAI Jun, XING Jibin

“…Objective To evaluate the effect of 0.5% ropivacaine for scalp nerve block on postoperative pain and recovery quality in craniotomy patients， and provide a reference for optimizing clinical anesthesia plans. Methods Sixty-six patients scheduled for craniotomy under general anesthesia were selected and randomly divided into ropivacaine group （R group） and control group （C group） in a 1∶1 ratio. …”
Get full text

Intraosseous endoscopic-assisted lesion debridement combined with free fibular vascularized transplantation for non-traumatic femoral head necrosis: A comparative study with core d... by Yalong Yang, Zhao Zhang, Yuanyuan Wei, Yang Li, Junliang Liu, Bo Wang, Shouhu Mi, Jintong Liu, Yongqiang Zhang, Yongming Guo, Meng Wu

“…This study compares the efficacy of endoscopy-assisted lesion debridement with free vascularized fibular grafting versus core decompression (CD) to identify a more effective surgical approach for treating osteonecrosis of the femoral head (ONFH). Methods This retrospective study included 83 patients with femoral head necrosis who were treated between January 2010 and December 2020. …”
Get full text

Predicting student achievement through peer network analysis for timely personalization via generative AI by Ivica Pesovski, Petar Jolakoski, Vladimir Trajkovik, Zuzana Kubincova, Michael A. Herzog

“…Building on these clusters, a novel AI-driven approach is introduced to personalize the learning experiences for each group, providing content aligned with students' predicted achievement levels and ensuring that students receive the right resources throughout their entire education. Methods: Bi-weekly surveys were conducted throughout the academic year with 45 students enrolled in a computer science program, where students nominated up to five peers they collaborated with the most. …”
Get full text

Decades of discovery: unveiling emerging trends, pivotal research areas, and landmark publications in national tobacco research in India by Alok Singh, Akanksha Kashyap, Saurabh Varshney, Sudip Bhattacharya

“…However, there is a need to map the growth and direction of this research to identify strengths, gaps, and emerging trends within the Indian context.MethodsA bibliometric analysis was conducted to evaluate tobacco-related research output affiliated with Indian institutions between 2003 and 2024. …”
Get full text

A prospective study on the effects of glucosamine hydrochloride and chondroitin sulfate combination on systemic inflammation markers in patients with knee osteoarthritis (report 1) by A. M. Lila, E. A. Taskina, L. I. Alekseeva, N. G. Kashevarova, E. A. Strebkova, N. M. Savushkina, N. M. Savushkina, T. A. Korotkova, A. S. Avdeeva, E. Yu. Samarkina, M. E. Diatroptov

“…Objective: to assess the effect of a combination of glucosamine hydrochloride (GH) 500 mg and chondroitin sulfate (CS) 500 mg (Artra®) on systemic inflammation markers in patients with knee osteoarthritis (KOA).Material and methods. The study included 70 patients with a confirmed diagnosis of KOA stage II–III and walking pain ≥4 points on a numerical rating scale (NRS). …”
Get full text

Impact of surgical margin status on the survival outcome after surgical resection of gastric cancer: a protocol for systematic review and meta-analysis by Bo Zhang, Yiqiong Yin, Zhaolun Cai, Yuan Yin, Chaoyong Shen, Jinming Huang

“…Therefore, we plan to conduct a systematic review and meta-analysis to quantitatively explore the role of R1 margin on gastric (including oesophagogastric junction) cancer survival after curative intent resection.Methods and analysis The protocol was conducted according to Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols guideline. …”
Get full text

Comparative analysis of the refractive and functional results of toric intraocular lens with wavefront-shaping mechanism implantation during the surgical treatment of cataracts i... by D.A. Khvan, G.A. Fedyashev

“…To evaluate the effectiveness of toric IOL with a wavefront shaping mechanism implantation in cataract surgical treatment in patients after PKP. Material and methods. This prospective study included 65 patients (65 eyes) who underwent cataract surgery after prevous PKP (the time after removal of corneal sutures averaged 1.4±0.8 years). …”
Get full text