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20901
Efficacy and Safety of Ultrasound-Guided Pulsed Radiofrequency Therapy of Stellate Ganglion on Refractory Painful Diabetic Peripheral Neuropathy
Published 2024-12-01“…Therefore, the study aimed to explore whether ultrasound-guided pulsed radiofrequency (PRF) therapy of the stellate ganglion (SG) in type 2 diabetes mellitus (T2DM) patients with painful DSPN could decrease pain severity and the need for analgesics.Methods: Fifty-six T2DM patients with refractory painful DSPN were enrolled in this study, who then received bilateral ultrasound-guided PRF therapy of SG. …”
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20902
Exploring Pain Empathy Among Doctors, Nurses and Patients: A Scoping Review
Published 2025-05-01“…The studies employed 75 distinct research tools, including the Empathy for Pain Scale (EPS), the Interpersonal Reactivity Index (IRI), pain empathy paradigms, and the Visual Analogue Scale (VAS), along with various detection technologies, such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG). …”
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20903
Changes in the ocular surface and meibomian glands following administration of 0.01 and 0.02% atropine
Published 2025-06-01“…PurposeTo investigate the changes in the ocular surface and meibomian glands following the administration of 0.01 and 0.02% atropine.SettingThe Second Affiliated Hospital of Anhui Medical University, Anhui, China.MethodsIn this randomized controlled study, the 0.01% group (18 patients, 36 eyes) and the 0.02% group (15 patients, 30 eyes) underwent assessments using the Ocular Surface Disease Index (OSDI), Visual Analogue scale (VAS), tear meniscus height (TMH), first noninvasive tear film breakup time (fNIBUT), and average noninvasive tear film breakup time (avNIBUT) at baseline (before administration) and at 1, 3, 6, and 12 months post-treatment. …”
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20904
Efficacy and Safety of Apremilast in Oncological Patients with Moderate-to-Severe Plaque Psoriasis: A 5 years Retrospective Observational Study
Published 2025-05-01“…However, data on its use in oncological patients remain limited.Methods: This retrospective observational study evaluated the efficacy and safety of Apremilast in 79 patients with a history of cancer who were treated for psoriasis and/or psoriatic arthritis over a period of approximately five years. …”
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20905
Building a Hand-Curated ceRNET for Endometrial Cancer, Striving for Clinical as Well as Medicolegal Soundness: A Systematic Review
Published 2025-04-01“…However, each RNA can interact with multiple targets, creating branched and intersected axes that, all together, constitute what is known as a competing endogenous RNA network (ceRNET). <b>Methods:</b> In this systematic review, we collected all available data from PubMed about experimentally verified (by luciferase assay) regulatory axes in endometrial cancer (EC), excluding works not using this test; <b>Results:</b> This search allowed the selection of 172 bibliographic sources, and manually building a series of ceRNETs of variable complexity showed the known axes and the deduced intersections. …”
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20906
Prediction efficiency and incremental processing strategy during spoken language comprehension in autistic children: an eye-tracking study
Published 2025-08-01“…This study addresses these gaps by investigating both prediction efficiency and incremental processing strategy during spoken language comprehension in autistic children compared to neurotypical peers. Methods Using the visual world paradigm, we compared 45 autistic children (3–8 years) with 52 age-, gender-, and verbal IQ-matched neurotypical children. …”
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20907
Cobalt Chloride-simulated Hypoxia Promoted Ossification of the Posterior Longitudinal Ligament Through the HIF1A–BMP4 Axis
Published 2025-06-01“…This study investigates the effects of cobalt chloride (CoCl2), which simulates an in vitro hypoxic microenvironment, on OPLL and explores its potential mechanisms, aiming to enhance our understanding of the pathogenesis of OPLL. Methods: Ligament cells were extracted from patients with OPLL and normal posterior longitudinal ligament (PLL) tissues, confirming their mesenchymal stem cell (MSC)-like properties. …”
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20908
Relationship between Hyponatremia and Peripheral Neuropathy in Patients with Diabetes
Published 2021-01-01“…This study was aimed at investigating the relationship between low serum sodium level and DPN in Chinese patients with type 2 diabetes mellitus. Methods. A retrospective study was performed on 1928 patients with type 2 diabetes between 2010 and 2018. …”
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20909
Health-related quality of life and productivity burden for non-professional caregivers of adults with rare diseases: a real-world study
Published 2025-06-01“…Patients’ mean (SD) EuroQol visual analogue scale (EQ VAS) score was 50.9 (23.3) and mean EQ-5D utility was 0.460 (0.350). …”
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20910
Cost utility analysis of acute rehabilitation approaches in the management of traumatic anterior shoulder dislocation
Published 2025-05-01“…Aims: We aimed to conduct a cost-utility analysis comparing one session of advice, supporting materials, and option to self-refer to physiotherapy with the same advice and materials, plus an additional programme of physiotherapy for people with a first-time, traumatic anterior shoulder dislocation. Methods: We conducted an economic evaluation within a randomized controlled trial from the UK NHS and personal social services (PSS) perspective. …”
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20911
The effect of listening to music and drawing on coping with dysmenorrhea complaints in nursing students: randomized controlled trial
Published 2024-10-01“…Abstract Aim To examine the effect of listening to music and drawing on coping with dysmenorrhea complaints of nursing students. Methods The study was a double-blind, three parallel-group randomized controlled trial conducted between August 2023 and May 2024 at Bartın University, Faculty of Health Sciences, Department of Nursing. …”
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20912
Construction of dynamic ceRNA regulatory networks in osteogenesis during fracture healing based on transcriptomic analysis
Published 2025-07-01“…This study aimed to investigate the key molecules involved in fracture healing and their potential competing endogenous RNA (ceRNA) regulatory mechanisms within the first 28 days post-fracture using bioinformatics methods. The experiment was conducted on 15 adult male SD rats, with tibia callus tissue samples collected at days 0, 3, 7, 14, and 28 (n = 3) post-fracture. …”
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20913
Real-World Outcomes of Allogeneic Immunosafe Plasma Rich in Growth Factors Eye Drops for Refractory Ocular Surface Diseases: A Prospective Observational Study
Published 2025-07-01“…We aimed to evaluate the safety and clinical outcomes of allogeneic is-ePRGF therapy for refractory OSD in real-world practice. Methods A single-center cohort was conducted involving consecutive patients with severe OSD nonresponsive to conventional therapy. …”
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20914
Midterm Outcomes Following Conversion of Failed Ankle Arthrodesis to Total Ankle Arthroplasty, Including Patients With a Deficient Fibula
Published 2025-07-01“…This retrospective study examines the midterm follow-up of 21 patients treated for a conversion of failed ankle arthrodesis by a single surgeon using a standard technique with a single prosthesis, with a focus on the treatment of 5 patients with a deficient distal fibula. Methods: Between May 2010 and August 2019, 27 patients underwent conversion using a prosthesis with an intramedullary tibial component, 21 of which were available for the study. …”
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20915
Indicators of rheumatoid arthritis disease activity. An association with a patient’s psychological status
Published 2020-05-01“…Objective: to study of the relationship between psychological factors and indicators of rheumatoid arthritis (RA) disease activity in patients who have been followed up for a long time after initiation of treat-to-target therapy.Patients and methods. The investigation enrolled 38 RA patients (29 women and 9 men) aged 33 to 80 years (mean age, 56.5±12.5 years) with a mean disease duration of 6.0±0.9 years. …”
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20916
Engagement and Follower Growth: Social Media Strategies of Swiss Athletes at the Paris Olympics
Published 2025-01-01“…This study investigates how athletic performance and social media behavior influence engagement and follower growth on Instagram among Swiss athletes during the Summer Olympic Games in Paris 2024. Methods The Instagram activity of the 128-member Swiss Olympic delegation to Paris 2024 was analyzed, focusing on posts made during the 2024 Olympics. …”
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20917
Gender characteristics of the course of toxoplasmic encephalitis in HIV-infected patients
Published 2025-04-01“…The purpose was to analyze the gender characteristics of TE in HIV-infected patients. Materials and methods. A retrospective analysis of the gender characteristics of the TE course was performed in 23 HIV-infected patients. …”
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20918
Elevated Blink Rates Predict Mind Wandering: Dopaminergic Insights into Attention and Task Focus
Published 2025-03-01“…This study sought to clarify the relationships between dopaminergic function and cognitive control during a task by utilizing EBR and EBV as proxy measures. Methods: Vertical electrooculogram and brain event-related potential (ERP) data were gathered from 24 adult participants while they performed a computerized cognitive task. …”
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20919
The Importance of the Correlation between CCT and Corneal Curvature in Refractive Surgery
Published 2025-06-01“…Background: The aim of this study was to analyze the relationship between central corneal thickness (CCT) and corneal curvature (CC) in patients with refractive anomalies and emmetropes, in three different age groups. Methods and Results: The study included 330 respondents, with a total of 660 eyes, divided into two groups. …”
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20920
Ocular graft host disease after allogeneic stem cell transplant: unique risk factors and outcomes
Published 2024-04-01“…Objective The aim of this study was to formulate a retrospective study investigating the ocular findings and associated risk factors in long-term survivors after allogenic-hematopoietic stem cell transplantation (HSCT) in Saudi Arabia. Patients and methods This observational study was conducted on patients who underwent HSCT from 1996 to 2016 at King Faisal Specialist Hospital and Research Center in Riyadh, Saudi Arabia. …”
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