Gallium Resistance in <i>Staphylococcus aureus</i>: Polymorphisms and Morphology Impacting Growth in Metals, Antibiotics and Polyfluorinated Compounds by Akamu Ewunkem, Felicia Simpson, David Holland, Tatyana Bowers, Ariyon Bailey, Ja’nyah Gore, Uchenna Iloghalu, Vera Williams, Sarah Adjei-Fremah, Larisa Kiki, Brittany Justice

“…This study utilized experimental evolution to test the evolvability of gallium resistance in <i>Staphylococcus aureus</i> and resistance traits potentially correlated with metals, antibiotics and polyfluorinated compounds, as well as its genomics foundations. Methods: Whole-genome sequencing was utilized to reveal functional networks of mutations associated with gallium resistance. …”
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Anti-Fibrotic Effect of Tacrolimus on Preventing Adhesion after Achilles Tendon Surgery in a Murine Model by Seyedeh Elnaz Nazari, Elnaz Ghorbani, Abdulridha Mohammed Al-Asady, Sayyed-Hadi Sayyed-Hosseinian, Farzad Rahmani, Ehsan Vahedi, Amir Avan, Mohammad-Mostafa Askarnia-Faal, Hamideh Naimi, Majid Khazaei, Seyed Mahdi Hassanian

“…This study aims to evaluate the repurposed potential of the immunosuppressive approved drug, tacrolimus, in decreasing adhesion band formation post-Achilles tendon surgeries in an animal model.Methods: Rats were randomly assigned to four groups: control, sham with surgical intervention but no adhesion, positive control group with surgical transection and adhesion received no treatment, tacrolimus group was the same as the positive control group except that rats were treated with 2 mg/Kg/day tacrolimus orally for 21 days. …”
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Lung ultrasound outperforms symptom-based screening to detect interstitial lung disease associated with rheumatoid arthritis by Wim Wuyts, Joseph Jacob, Patrick Verschueren, Veerle Taelman, Barbara Neerinckx, Heleen Cypers, Alexandros Kalkanis, Nico De Crem, Marie Vermant, Tinne Goos, Emanuela Elsa Cortesi, Tine Follet, Stefan Gogaert, Nathalie Veyt, Laurens J De Sadeleer

“…We assessed the role of symptoms and lung ultrasound (LUS) as potential screening tools.Methods 116 adult patients with RA presenting to the rheumatology outpatient clinic underwent high-resolution CT (HRCT) scans, pulmonary function tests, LUS (72 zones) and completed a Visual Analogue Scale (VAS) for cough and modified Medical Research Council dyspnoea scale (mMRC). …”
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Preliminary results of the EPIDIA4Kids study on brain function in children: multidimensional ADHD-related symptomatology screening using multimodality biometry by Yanice Guigou, Alexandre Hennequin, Théo Marchand, Théo Marchand, Mouna Chebli, Lucie Isoline Pisella, Pascal Staccini, Pascal Staccini, Vanessa Douet Vannucci, Vanessa Douet Vannucci

“…Currently, early diagnosis is constrained by clinical complexity and limited resources of professionals to conduct evaluations. Scalable methods for ADHD screening are thus needed. Recently, digital epidemiology and biometry, such as the visual, emotional, or digit pathway, have examined brain dysfunction in ADHD individuals. …”
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Therapeutic effect of focused-extracorporeal shockwave therapy on muscular and adjacent tissue stiffness and pain changes in myofascial pain syndrome: A randomized controlled trial... by Pijakkana Vasvit, Kultida Klarod, Oranat Sukkho, Sirirat Kiatkulanusorn, Phurichaya Werasirirat, Xue-Qiang Wang, Yong-Hui Zhang, Juntip Namsawang, Pornpimol Muanjai, Nongnuch Luangpon

“…This study aimed to investigate the effectiveness of fESWT and sham-fESWT in alleviating muscular stiffness, pain, and functional disability. Methods: Sixty-four office workers (mean age 31.4 ± 9.5 years) with myofascial pain syndrome of the upper trapezius were randomly and equally assigned to receive either the fESWT or sham-fESWT. …”
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Histological Grade, Tumor Breadth, and Hypertension Predict Early Recurrence in Pediatric Sarcoma: A LASSO-Regularized Micro-Cohort Study by Alexander Fiedler, Mehran Dadras, Marius Drysch, Sonja Verena Schmidt, Flemming Puscz, Felix Reinkemeier, Marcus Lehnhardt, Christoph Wallner

“…This exploratory study aimed to identify clinical features associated with first tumor recurrence using a machine learning approach tailored to low-event settings. <b>Methods</b>: We conducted a retrospective, single-center cohort study of 23 pediatric patients with histologically confirmed sarcoma. …”
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Comprehensive 1-year multilevel study of sports injuries in para athletes: impact of season timing, years of sports experience, impairment and sports type by Evert Verhagen, Erik Witvrouw, Evi Wezenbeek, Fernanda Madaleno, Juliana Ocarino, Renan Resende, Marco Túlio de Mello, Andressa Silva, Larissa Pinheiro, Mauro Heleno Chagas, Dawit Gonçalves

“…Objectives Investigate the associations between season timing, sports experience, impairments and sports type with injuries and time loss among para athletes over a 50-week sports season.Methods Data were collected in 2022 from two Brazilian Paralympic Centres, including para athletes competing in para swimming, para athletics, para powerlifting and para taekwondo. …”
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Psychometric properties of the pain anxiety symptom scale among postoperative patients in Amol, Iran by Hamid Sharif-Nia, Hamid Sharif-Nia, Erika Sivarajan Froelicher, Erika Sivarajan Froelicher, João Marôco, Esmaeil Hoseinzadeh, Sima Hejazi, Sima Hejazi, Reza Fatehi, Poorya Nowrozi, Bita Mohammadi

“…Therefore, this study was conducted to determine the validity and reliability of the Persian version of the Pain Anxiety Symptom Scale among a group of Iranian patients in Amol.MethodsThis methodological study was conducted in 2023 with a sample of 400 postoperative patients from Amol, Iran, selected through convenience sampling. …”
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Acupuncture for chronic nonspecific low back pain in middle-aged and older patients: A randomized controlled trial by Fei XU, Kai-qiong JIAO, Lin-peng WANG, Fan ZHANG

“…Objective: To observe the specific effects of acupuncture in middle-aged and older patients with chronic nonspecific low back pain (CNSLBP). Methods: Sixty-six patients with CNSLBP were randomized into the acupuncture or sham acupuncture groups (n = 33). …”
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Implementation and Pilot Data on Diabetic Retinopathy in a Teleophthalmology Program at a Multispecialty Primary Care Clinic by Joanne B. Tayapad, MD, Alfonso U. Bengzon, MD, Sherman O. Valero, MD, Milagros H. Arroyo, MD, Ricardo Tobias M. Papa, MD, Egidio Jose S. Fortuna, MD, Jocelyn G. Erni, BS, Myra Alisa J. Reyes, RN, Jerry D. Cavallerano, OD PhD, Lloyd Paul Aiello, MD PhD, Paolo S. Silva, MD

“…Objective: To report on the implementation and initial pilot data of diabetic retinopathy (DR) identified using a validated telemedicine program for DR in a multispecialty primary care clinic. Methods: This was a retrospective, cross-sectional pilot survey of diabetic patients imaged for the first time at the telemedicine program of The Medical City from November 26, 2012 to August 31, 2013. …”
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Habitat radiomics assists radiologists in accurately diagnosing lymph node metastasis of adenocarcinoma of the esophagogastric junction by Pingfan Jia, Yueying Li, Haonan Li, Yuan Li, Huijuan Qin, Anyu Xie, Yuru Li, Luyao Wang, Luqin Ke, Huijie Feng, Hongwei Yu, Juan Li, Ning Yuan, Xing Guo

“…Abstract Objectives This study aimed to develop a habitat radiomics (HR) model capable of preoperatively predicting lymph node metastasis (LNM) in adenocarcinoma of the esophagogastric junction (AEG) and to implement its use in clinical practice. Methods In this retrospective analysis, 337 patients from three centers were enrolled and divided into three cohorts: training, validation, and test (208, 52, and 77 patients, respectively). …”
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‘Water is life’: developing community participation for clean water in rural South Africa by Kathleen Kahn, Rhian Twine, Jennifer Hove, Lucia D'Ambruoso, Denny Mabetha, Maria van der Merwe, Peter Byass, Sonto Khosa, Sophie Witter

“…The objectives were to develop local knowledge on health priorities in a rural province as part of a programme developing community evidence for policy and planning.Methods We engaged 24 participants across three villages in the Agincourt Health and Socio-Demographic Surveillance System and codesigned the study. …”
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Repeated Cranial and Large‐Vessel Positron Emission Tomography/Computed Tomography Scans and the Association With Structural Aortic Disease in Giant Cell Arteritis: A Five‐Year Obs... by Anthony M. Sammel, Ivan Ho Shon, Daniel A. Moses, Stacey Fredericks, Gita Mathur, Claudia M. Hillenbrand, Edward Hsiao, Geoffrey Schembri, Rodger Laurent, Eva A. Wegner

“…Scans were reported for overall metabolic disease activity and a visual FDG avidity grade at each vascular territory. …”
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Neuroadaptive changes in brain structural–functional coupling among pilots by Xi Chen, Qingbin Meng, Qingsong Song, Peiran Xu, Shicong Zhang, Donglin Huang, Qi Chu, Jiamin Fan, Cheng Luo, Xiuyi Li

“…However, prior research has predominantly focused on identifying structural and functional differences in the brain, while the relationship between structure and function remains insufficiently elucidated.MethodsThis study collected T1-weighted structural magnetic resonance imaging (MRI), resting-state functional MRI (rs-fMRI), and diffusion tensor imaging (DTI) data from 47 pilots and 38 matched controls. …”
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Evaluation of blood flow in arteritic anterior ischemic optic neuropathy using laser speckle flowgraphy: A case series by Chiaki Yamaguchi, Naoki Kiyota, Noriko Himori, Takahiro Oshima, Takayuki Takeshita, Kazuko Omodaka, Satoru Tsuda, Toru Nakazawa

“…This disease results in significant ocular blood flow (BF) impairment, though data on ocular hemodynamics are limited. Methods: This observational case series enrolled four patients treated for AAION (age: 81.8 ± 7.8 years; male to female ratio: 3:1) who underwent laser speckle flowgraphy (LSFG) scanning at the initial visit and after steroid treatment in both eyes. …”
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Long-term Quality of Life After Intensive Care Unit Admission (a Single-Center Observational Study) by C. Leggieri, L. Dezza, B. Oltolini, R. Lembo, B. Noto, S. M. Villa, A. Belletti, G. Lombardi, A. Battaini, E. Pedrini, C. F. Zuccato, A. Zangrillo

“…The relative contribution of each of these components to long-term quality of life was never investigated.The aim of this study is to identify the type and severity of disability and QoL at the discharge from ICU and up to following 6 months.Material and Methods. All patients (n=218) discharged from a university hospital ICU between April 2016 and July 2017 were eligible. …”
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iTBS on RDLPFC improves performance of motor imagery: a brain-computer interface study combining EEG and fNIRS by Jialin Chen, Quan Liu, Gengbin Chen, Guiyuan Cai, Junbo Jiang, Xueru Yang, Chunqiu Tan, Cailin Zhang, Guangqing Xu, Yue Lan

“…This study aimed to enhance motor imagery ability and MI-BCI performance by modulating the excitability of the right dorsolateral prefrontal cortex (RDLPFC) through intermittent theta-burst stimulation (iTBS), inducing neuroplastic changes. Methods Fifty-two healthy right-handed participants were randomly assigned to either the iTBS or sham group. …”
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The Effect of Rosa Foetida Extract along with Self-Care Education on Primary Dysmenorrhea: A Prospective Randomized Clinical Trial by Fatemeh Shabani, Shabnam Omidvar, Parvin Sajadi Kaboudi, Hajar Pasha, Soraya Khafri, Hossein Najafzadehvarzi, Fatemeh Nasiri-Amiri, Mahbobeh Faramarzi, Zinatossadat Bouzari

“…The purpose of this study was to determine the effect of Rosa Foetida extract along with self-care behaviors on primary dysmenorrhea. Methods: A randomized clinical trial was conducted on 135 students residing in dormitories. …”
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Evolving multimorbidity patterns among ageing adults with cardiovascular disease continuum in Southwest China: A longitudinal cohort study by Xiaoya Qi, Ziyue Zhang, Meng Jia, Yangping Zhang, Shuang Feng, Ruixue Bai, Siyao Wang, Jinning Mao, Shu Su

“…This study investigates the longitudinal evolution of cardiovascular disease continuum (CVDC)-related multimorbidity patterns in this population. Methods: The observational study analyzed medical examination reports from individuals aged 65 and older who underwent regular physical examinations during January 1, 2010 to December 31, 2022 at the Second Affiliated Hospital of Chongqing Medical University. …”
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Home-based self-administered transcranial direct current stimulation for women affected by primary dysmenorrhoea in Northeastern Brazil: a protocol study by Thiago Anderson Brito De Araújo, Edson Silva-Filho, Rodrigo Pegado, Tatiana Camila de Lima Alves da Silva, Yvinna Tamiris Rodrigues, Paloma Cristina Alves de Oliveira, Ervinas Bernatavicius, Alexander Anthony Cook, Emilè Radytè, Maria Thereza Micussi

“…This protocol aims to evaluate the effects of home-based self-administered tDCS for pain, premenstrual symptoms, physical performance, quality of life, electroencephalography and patient global impression in women affected by primary dysmenorrhoea.Methods and analysis This is a single-centre, parallel, randomised, double-blinded clinical trial protocol. 40 women affected by primary dysmenorrhoea will be randomised into two groups (active-tDCS or sham-tDCS). …”
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