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20561
Health‐Related Quality of Life One Year After Intensive Care Unit Admission for COVID‐19: A Retrospective, Cross‐Sectional, Longitudinal Observational Study
Published 2025-02-01“…Therefore, the aims were to describe HRQoL and to identify early factors associated with impaired HRQoL 1 year after ICU admission following COVID‐19. Methods This retrospective, cross‐sectional, longitudinal observational study assessed HRQoL 1 year after ICU admission for COVID‐19 during the first wave of the pandemic. …”
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20562
Development of Predictive Nomograms for Clinical Use to Quantify the Risk of Amputation in Patients with Diabetic Foot Ulcer
Published 2021-01-01“…To determine the novel proposed nomogram model accuracy in the prediction of the lower-extremity amputations (LEA) risk in diabetic foot ulcer (DFU). Methods and Materials. In this retrospective study, data of 125 patients with diabetic foot ulcer who met the research criteria in Zhongnan Hospital of Wuhan University from January 2015 to December 2019 were collected by filling in the clinical investigation case report form. …”
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20563
Effects of remimazolam and propofol on sleep rhythm and delirium after spinal surgery in elderly patients
Published 2025-02-01“…Abstract Objective This study aims to investigate the effects of remimazolam on postoperative melatonin secretion, sleep rhythm, and postoperative delirium (POD) in elderly patients undergoing spinal surgery. Methods We selected 120 elderly patients scheduled for elective spinal surgery (lumbar interbody fusion via a posterior approach) under general anaesthesia from November 2023 to January 2024. …”
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20564
Adalimumab in Focus: Evaluating Effectiveness and Safety in Non-Infectious Uveitis at a Tertiary Referral Center in Türkiye
Published 2025-08-01“…Objectives: To evaluate the indications, efficacy, and safety of adalimumab (ADA) in treating active non-infectious uveitis (NIU) in the Turkish population in a real-world setting. Materials and Methods: This retrospective observational study included patients diagnosed with NIU treated with ADA on-label. …”
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20565
Predictive Value of Optical Coherence Tomography Biomarkers in Patients with Persistent Diabetic Macular Edema Undergoing Cataract Surgery Combined with a Dexamethasone Intravitrea...
Published 2025-05-01“…Limited data exist on the role of optical coherence tomography (OCT) biomarkers as predictors of success in non-responders to anti-VEGF treatment undergoing simultaneous cataract surgery and dexamethasone intravitreal implant (DEX-I). <b>Methods:</b> This study was designed as a retrospective analysis of patients with DME who were refractory to anti-VEGF treatment but underwent cataract surgery and received a DEX-I at the time of surgery. …”
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20566
Association of alcohol abstinence with risk of hyperuricemia in rural Chinese adults: the Henan Rural Cohort Study
Published 2025-02-01“…This study aimed to evaluate the associations of abstinence with HUA in rural Chinese adults. Methods This was a cross-sectional study of 38,855 participants (15,371 males and 23,484 females) using the baseline data (2015–2017) from the Henan Rural Cohort Study. …”
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20567
Genome-wide identification of PP2A gene family in Camellia sinensis reveals the potential role of CsPP2A-TON2/FASS1 in abiotic stress
Published 2025-05-01“…Protein phosphatase 2A (PP2A) are a class of Ser/Thr protein phosphatases which are present widely across plant species and facilitate plant responses to biotic and abiotic stresses, and hormone treatment. Methods Using BLASTp, tea PP2A genes were found and their physicochemical characteristics (ExPASy), subcellular localization, and intron-exon structure (GSDS) were described. …”
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20568
Predictors and Correlates of Depression and Anxiety Symptom Trajectories in a Large Digital Mental Health Provider: Retrospective Analysis of Data From Rula Health
Published 2025-07-01“…We aimed to (1) explore the trajectories of anxiety and depression symptoms and (2) examine the impact of demographics and primary diagnosis on depression and anxiety trajectories. MethodsWe retrospectively analyzed longitudinal symptom data from adults receiving therapy through Rula Health, an MBC-based DMHI. …”
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20569
Early Effects of Perfluorohexyloctane Ophthalmic Solution on Patient-Reported Outcomes in Dry Eye Disease: A Prospective, Open-Label, Multicenter Study
Published 2025-02-01“…This study evaluated patient-reported outcomes early in treatment with PFHO. Methods This prospective, multicenter, open-label, phase 4 study enrolled adults with a history of DED for ≥ 6 months. …”
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20570
Analysis of Quality Indicators of Preanalytical and Analytical Phases in Cervical Pap Smear Cytology: A Cross-sectional Study
Published 2025-04-01“…Aim: To assess the quality indicators of the preanalytical and analytical phases of cervical Pap smear cytology in order to evaluate Non Conformity (NC) through root cause analysis for appropriate corrective and preventive measures. Materials and Methods: The cross-sectional study was conducted in the cytology section of the Department of Pathology at Mahatma Gandhi Medical College and Research Institute in Puducherry, India, planned and executed over a period of twelve months, starting in June 2023 and concluding in May 2024. …”
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20571
Shared pyroptosis pathways and crosstalk genes underpin inflammatory links between periodontitis and atherosclerosis
Published 2025-03-01“…The goal was to uncover common regulatory mechanisms underlying these two inflammatory conditions. Methods: Gene expression datasets for PD (GSE10334) and AS (GSE43292) were retrieved from public databases. …”
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20572
Pattern and Prevalence of Retinal Vein Occlusion in Bhutan: A 3-Year National Survey at Vitreoretinal Clinics
Published 2024-10-01“…Bhim B Rai,1,2 Phuntsho Dorji,2 Ted Maddess1 1John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; 2Department of Ophthalmology, JDW National Referral Hospital, Thimphu, BhutanCorrespondence: Bhim B Rai, Building 131, Garran Road, John Curtin School of Medical Research, Australian National University, Canberra, ACT, 2601, Tel +61 2 61259253, Email bhim.rai@anu.edu.auPurpose: We conducted this study to determine the pattern and prevalence of retinal vein occlusion (RVO) in Bhutan to inform national health policy as no data has been compiled previously.Methods: A retrospective cross-sectional survey was conducted over 3 years, including all new RVO cases. …”
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20573
Short Term Outcomes Utilizing Custom Total Talus Replacement with Subtalar Arthrodesis for Revision and Complex Total Ankle Arthroplasty
Published 2024-12-01“…Our hypothesis is that custom 3D printed talar body replacements lead to good outcome scores and patient satisfaction scores. Methods: We performed a retrospective chart review on 8 patients (9 TTRs) who underwent a TTR at our institution between May 2019 and October 2023. …”
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20574
Natural history of the aortic wall changes in adults with the degenerative tricuspid aortic valve stenosis: The morphometric proofs and implications for echocardiography
Published 2019-01-01“…The aim of this study was to grade the histopathological changes in the wall of the nonseverely dilated ascending aorta in patients with the severe, calcific TAV stenosis and to correlate them with the echocardiographic parameters in order to analyze when the ascending aorta should be replaced simultaneously with the aortic valve replacement (AVR). Methods. The samples from 37 patients subjected to the AVR and the samples from the control group were analyzed morphologically. …”
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20575
Risk Factors for Correction Loss of Vertebral Slippage after Minimally Invasive Transforaminal Lumbar Interbody Fusion Surgery for Lumbar Degenerative Spondylolisthesis
Published 2025-07-01“…We aimed to identify the risk factors for correction loss after minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) and to determine the effect of postoperative correction loss on postoperative clinical outcomes. Methods: In this retrospective study, a total of 111 patients (mean age 69.5 years, 37 men and 74 women) who underwent single-level MIS-TLIF with slippage reduction for lumbar degenerative spondylolisthesis and were followed up for >1 year were included in the study. …”
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20576
Factors influencing outcome satisfaction after cataract surgery: patient-reported insights from the RayPro database
Published 2024-12-01“…The purpose of this study is to investigate determinants of patient satisfaction following cataract surgery by analysing PROMs. Methods A multicentre, retrospective, observational study was conducted analysing the PROMs recorded in the RayPro database (Rayner, Worthing, UK) from May 2019 to February 2024. …”
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20577
Anatomic and Functional Outcomes of Lamellar Macular Hole and Epiretinal Membrane Foveoschisis Surgery: Predictive Factors and Associated Complications — A Retrospective Inte...
Published 2025-04-01“…Yosra Er-reguyeg,1 Sihame Doukkali,2 Mélanie Hébert,2 Eunice Linh You,2 Serge Bourgault,2 Mathieu Caissie,2 Éric Tourville,2 Ali Dirani2 1Faculty of Medicine, Laval University, Quebec City, Quebec, Canada; 2Department of Ophthalmology, Hospital Saint-Sacrement, Laval University, Quebec City, Quebec, CanadaCorrespondence: Ali Dirani, Hôpital du Saint-Sacrement, 1050 Chemin Sainte-Foy, Québec, QC, D2-44C, Canada, Tel +1 418 525 4444, Email drdirani@gmail.comPurpose: To analyze the anatomic and functional outcomes of lamellar macular hole (LMH) and epiretinal membrane foveoschisis (ERMF) surgery.Patients and Methods: This is a retrospective interventional cohort study of ninety patients with unilateral idiopathic LMH or ERMF who underwent pars plana vitrectomy (PPV) with membrane peeling between 2014 and 2021. …”
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20578
Social behavioral analysis of the influence of residential area and grade on pupils’ myopia rate: a cross-sectional survey in Nanjing, China
Published 2025-03-01“…ObjectiveThis study aims to examine the prevalence of myopia among pupils in different residential areas (city center, nearby suburbs, and far suburbs) and grade levels (lower, middle, and upper), analyzing social behaviors and risk factors to guide early intervention.MethodsA cross-sectional survey was conducted with elementary students across various regions in Nanjing. …”
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20579
Real-world clinical insights and aqueous humor biomarker analysis of diabetic macular edema subtypes classified by OCT following intravitreal injections
Published 2025-07-01“…Methods Ninety-four eyes from seventy-eight patients were enrolled between July 1, 2018, and June 30, 2023. …”
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20580
[Translated article] The influence of socioeconomic status and psychological factors on surgical outcomes of the carpometacarpal osteoarthritis of the thumb
Published 2025-03-01“…Objective: This study aimed to investigate to what extent people with carpometacarpal thumb osteoarthritis that are socioeconomically disadvantaged and have psychological disorders report higher pain levels and worse patient-rated upper-extremity functionality after surgical treatment. Material and method: A single centre, retrospective observational cohort study analysing 100 patients diagnosed with thumb carpometacarpal osteoarthritis between 2013 and 2019. …”
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