Application of integral suture for medial hernia defect closure in eTEP hernioplasty for direct inguinal hernia by R. I. Barzak, A. V. Yuri, D. A. Tischenko, B. B. Orlov, I. A. Semenenko, N. R. Kopteev, V. A. Kashchenko

“…The OBJECTIVE was to evaluate the immediate and long-term results of integral suture application and to determine the indications for its use in eTEP hernioplasty for primary rectal inguinal hernia in men.METHODS AND MATERIALS. A prospective single-center double-blind randomized controlled study on the basis of the City Clinical Hospital named after S. …”
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Evaluating the immunogenicity and safety of ID93 + GLA-SE in BCG-vaccinated healthy adults: a systematic review and meta-analysis of randomized controlled trials by Erum Siddiqui, Mohammad Saad Khan, Maliha Khalid, Harshika Khaim Chandani, Umaimah Naeem, Muhammad Mohsin Khan, Syed Owais Wasti

“…Objective: To evaluate the immunogenicity and safety of ID93 + GLA-SE in BCG-vaccinated healthy adults. Methods: A comprehensive electronic search on PubMed (Medline), ScienceDirect, EMBASE, Scopus, and Cochrane Central database was conducted from inception till August 2024 for randomized controlled trials (RCTs) with a target population of BCG-vaccinated healthy adults. …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…The Pediatric Awareness and Sensory Motor Assessment (PASMA) was created to fill this gap, providing sensitive measurement of sensory awareness and motor response across five domains (i.e., olfactory, visual, auditory, gustatory, and tactile).MethodsIn this retrospective study, a Rasch analysis was conducted on PASMA data for CMC. …”
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Short-term real-world effectiveness of faricimab on macular edema due to retinal vein occlusion by Toshiaki Hirakata, Ai Toride, Kenta Ashikaga, Takanori Nakagawa, Fumihiro Hara, Yuta Nochi, Shutaro Yamamoto, Yoshimune Hiratsuka, Shintaro Nakao

“…Best-corrected visual acuity (BCVA) and central macular thickness (CMT) were analyzed. …”
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Prevalence of oncogenic human papillomavirus (HPV 16/18) infection, cervical lesions and its associated factors among women aged 21-49 years in Amhara region, Northern Ethiopia. by Minwuyelet Maru Temesgen, Tefera Alemu, Birtukan Shiferaw, Seid Legesse, Taye Zeru, Mahteme Haile, Tesfaye Gelanew

“…This study aimed to determine the prevalence of HPV infection and factors contributing to the progression of HPV infection to cervical cancer.<h4>Methods</h4>Facility-based cross-sectional study design was employed among women aged 21 to 49 years of age who came for routine cervical cancer screening to 4 randomly selected hospitals (2 general and 2 referral) of Amhara region from May to October, 2019. …”
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The Two-Year Outcomes of Phacoemulsification Combined with GATT Versus Standalone GATT in Open-Angle Glaucoma: A Comparative Study by Zübeyir Yozgat, Mehmet Cem Sabaner

“…<b>Background/Objectives</b>: The aim of this paper was to evaluate the two-year outcomes of phacoemulsification combined with gonioscopy-assisted transluminal trabeculotomy (PHACO-GATT) versus standalone GATT in terms of efficacy, safety, and surgical success. <b>Methods</b>: This retrospective, comparative study included 64 eyes of 64 patients with moderate-to-severe open-angle glaucoma: 35 patients (54.7%) with primary open-angle glaucoma (POAG) and 29 patients (45.3%) with pseudoexfoliative glaucoma (PEG). …”
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Comparative effectiveness and safety of tofacitinib vs. adalimumab in patients with rheumatoid arthritis: A systematic review and meta-analysis by Chunyan Zhu, Yibo Zheng, Zilu Wang, Guozong Chen, Yushi Li

“…ObjectivesTo provide the latest systematic review and meta-analysis comparing the effectiveness and safety of tofacitinib and adalimumab in rheumatoid arthritis (RA) patients.MethodsA systematic search of PubMed, Embase, Web of Science, and Cochrane databases was conducted until April 2025. …”
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Clinical manifestations, histopathological changes and quality of life in patients with advanced knee osteoarthritis caused by age, trauma, obesity and their combination by Kristina V. Korochina, Tatyana V. Chernysheva, Irina E. Korochina

“…Objective — to reveal and analyze clinical characteristics, knee joint histopathology, and quality of life in patients at late stages of knee osteoarthritis (OA) triggered by age, trauma, metabolic syndrome, or their combination. Material and methods — We studied 120 subjects with knee OA (sensu Altman R.D., 1991) of Kellgren-Lawrence Grades 3-4. …”
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Neuromuscular exercise in addition to celecoxib versus celecoxib alone for symptomatic and radiographic knee osteoarthritis: a randomized controlled trial by Xiaotian Yang, Haixin Song, Xuqing Li, Tao Wu, Jianhua Li, Chengqi He

“…The aim of this study was to investigate the effects of NEXA in addition to celecoxib compared to celecoxib alone on pain and physical function in patients with symptomatic and radiographic knee OA. Methods A prospective, assessor-blinded, two-arm, superiority randomised controlled trial. …”
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Ocular Hypertension Following Open Globe Injury in Patients Undergoing Pars Plana Vitrectomy by Karimaghaei S, Al-Hindi H, Chauhan MZ, Elhusseiny AM, Sanvicente CT, Uwaydat SH

“…Sam Karimaghaei, Hytham Al-Hindi, Muhammad Z Chauhan, Abdelrahman M Elhusseiny, Carina T Sanvicente, Sami H Uwaydat Harvey and Bernice Jones Eye Institute, Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, AR, USACorrespondence: Sami H Uwaydat, Department of Ophthalmology, Jones Eye Institute, University of Arkansas for Medical Sciences, 4301 W Markham Street &num; 523, Little Rock, AR, 72205, USA, Email SHUwaydat@uams.eduPurpose: To identify risk factors and rates of post-traumatic ocular hypertension (OHT) in patients undergoing pars plana vitrectomy (PPV) for open-globe injuries.Patients and Methods: Retrospective chart study including 98 eyes from 98 patients between 2008 and 2022 with open globe injuries who were hospitalized at a single academic institution and received first repair or exploration followed by PPV. …”
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Affects for stress reaction and hemodynamics by multimodal opioid free anesthesia on patients with video-assisted thoracoscopic surgery by WU Meichao, YANG Fangfang, CAI Ning, MA Xingjun

“…Objective To compare the hemodynamics and stress reaction of opioid free anesthesia (OFA) and opioid anesthesia (OA) in patients undergoing video-assisted thoracoscopic surgery. Methods A total of 110 patients who underwent thoracoscopic bullectomy or lobectomy under general anesthesia at Fuyang People’s Hospital from January to October 2023 were randomly divided into OA group (n=55) and OFA group (n=55). …”
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Dual plating in the management of nonunion complex distal femur fractures following lateral locked plate fixation: radiological and functional outcomes of a prospective study by Nilesh Barwar, Gypsy Gargi, Ankit Rai, Abhay Elhence, Sumit Banerjee, Nitesh Gahlot

“…Revision surgery was performed by applying dual plates, and their efficiency was evaluated. Methods This study investigated 24 aseptic and 3 septic nonunions of distal femur fractures, classified as AO/OTA type C, that were previously managed with open reduction and internal fixation using only a lateral locked plate. …”
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X-RAY ASSESSMENT OF JAW BONE TISSUE IN PATIENTS WITH SYSTEMIC OSTEOPOROSIS BEFORE THE SURGICAL STAGE OF DENTAL IMPLANTATION by M.A. Datsenko

“…The aim of the study – to conduct a comparative analysis of the condition, structure and mineral density of jaw bone tissue in patients with systemic osteoporosis, depending on the sex, before the surgical stage of dental implantation. Materials and Methods. The condition, structure and density of bone tissue before the surgical stage of dental implantation were determined in 87 patients who needed dental implantation. …”
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Long‐term survival outcomes of patients with primary ocular adnexal MALT lymphoma: A large single‐center cohort study by Yuanzheng Liang, Rui‐ying Fu, Xue‐lin Liu, Xin‐di Liu, Ying‐shi Piao, Jian‐min Ma, Liang Wang

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Combining gene expression microarrays and Mendelian randomization: exploring key immune-related genes in multiple sclerosis by Shuangfeng Ding, Yunyun Zhang, Yunzhe Tang, Ying Zhang, Mingyuan Liu

“…This study aims to explore potential immune-related genes associated with MS and assess the causal relationship between these genes and the risk of developing MS.MethodsWe retrieved expression datasets of peripheral blood mononuclear cells from MS patients from the Gene Expression Omnibus (GEO) database. …”
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Comparative evaluation of central serous retinopathy in pilots and non-pilot patients by Yan-Yan Zhao, Hua Wang, Wei Chen, Quan Wang, Yong Liu

“…The objective of this study was to evaluate the clinical diagnosis, treatment, and aviation medical assessment principles for CSC in military pilots. Methods: The clinical data and aviation medical assessments of 15 pilots with CSC who were admitted to the Air Force Medical Center between January 2003 and December 2021 were analyzed, and three typical cases were reported. …”
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Microplastic detectives: a citizen-science project reveals large variation in meso- and microplastic pollution along German coastlines by Bruno Andreas Walther, Franco Pasolini, Franco Pasolini, Špela Korez Lupše, Melanie Bergmann

“…Here, we describe in detail 1) how we recruited, instructed, and engaged citizen scientists, 2) why we chose bulk sampling over reduced-volume sampling, and 3) the laboratory methods we used. The citizen scientists collected 1,139 samples from 71 locations along the German coast, totalling 2.2 tons of sand. …”
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The acute cross-education effect of foam rolling on the thigh muscles in patients after total knee arthroplasty by Masanobu Yokochi, Masanobu Yokochi, Masatoshi Nakamura, Ayaka Iwata, Ryota Kaneko, Noboru Yamada, Andreas Konrad

“…In this study, we aimed to expand this knowledge for TKA rehabilitation and investigated the acute effects of FR intervention on the non-operative side on ROM, stiffness, and pain of the operative side in postoperative patients within the first week after TKA.Materials and methodsThe study employed a randomized crossover design: 20 patients (mean age 75.0 ± 7.8 years) in the first postoperative week after TKA were divided alternately into Roll_Break and Break_Roll groups in the order of prescription. …”
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Spontaneous Associations under Mild Compression of the Hippocampal Area by Olga A. Krotkova, Arina N. Kiseleva, Alesia S. Bichkova, Mariya U. Kaverina

“…The groups were comparable in terms of morphometric characteristics of the tumors, degree of hemisphere compression, and socio-demographic factors. Methods. The study consisted of two sessions at rest, each lasting 3 minutes. …”
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Revision hip arthroscopy for hip synovial chondromatosis is effective despite inferior postoperative clinical outcomes compared to patients undergoing primary hip arthroscopy: a ma... by Yichuan Zhu, Xin Zhang, Jianquan Wang, Guanying Gao, Yan Xu

“…Abstract Purpose (1) To determine the clinical outcomes following revision arthroscopy for patients with hip synovial chondromatosis (SC), and (2) to compare the clinical outcomes between patients undergoing revision hip arthroscopy and primary hip arthroscopy. Methods Patients undergoing hip arthroscopy between December 2014 and January 2021 was reviewed. …”
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