Sub-Perfluorocarbon Ophthalmic Viscoelastic Injection (SPOT) technique for macular hole retinal detachment surgery by Hung-Da Chou, Wee Min Teh, Kuan-Jen Chen, Yih-Shiou Hwang, Laura Liu, Ling Yeung, Wei-Chi Wu, Chi-Chun Lai

“…The purpose of this extended study is to report the outcomes in a larger cohort with a longer follow-up. Methods A retrospective case series of 20 eyes with MHRD that underwent vitrectomy with internal limiting membrane (ILM) peeling and inverted flap (16 eyes, 80%), ILM insertion (3 eyes, 15%), or ILM free flap (1 eye, 5%) assisted by the SPOT technique in a tertiary referral center. …”
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Association of glutamine metabolites in synovial fluid with the severity of temporomandibular joint osteoarthritis by Zhiqiang Song, Yingjie Xu, Chenxi Li, Bo Shao, Zhongcheng Gong

“…Correlations between these factors and TMJ-OA severity were assessed, and changes in these factors before and after hyaluronic acid (HA) treatment were analysed. Methods SF samples from 30 patients with unilateral TMJ-ID and unilateral TMJ-OA were analysed, along with visual analogue scale (VAS) scores, maximum mouth opening (MMO), and radiographic stages. …”
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Therapeutic potential of miR-204-5p in intervertebral disc degeneration: targeting the SSRP1/NF-κB pathway to inhibit apoptosis by Chenhao Zhao, Qiuwei Li, Cailiang Shen

“…Mendelian randomization (MR), experimental validation, and bioinformatics analysis were used. Methods We began with bidirectional MR analysis to explore the causal relationships between 40 microRNAs and IVDD, identifying miR-204-5p as negatively correlated with IVDD. …”
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Reporting of Safety Events during Anti-VEGF Treatment: Pharmacovigilance in a Noninterventional Trial by Focke Ziemssen, Thomas Hammer, Matthias Grueb, Bettina Mueller, Hüsnü Berk, Maria-Andreea Gamulescu, Jessica Voegeler, Joachim Wachtlin, OCEAN Study Group

“…The prospective, noninterventional OCEAN study assessed the safety of intravitreal ranibizumab injections for treatment of neovascular age-related macular degeneration, diabetic macular edema, and retinal vein occlusion under real-world conditions in Germany. Methods. Adults receiving ≥1 ranibizumab (0.5 mg) injections were recruited by 369 ophthalmologists and followed for 24 months. …”
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HIGH HEART RATE AS A POTENTIAL RISK FACTOR FOR DEVELOPMENT OF CARDIOVASCULAR DISEASES IN WOMEN WITH RHEUMATOID ARTHRITIS by D. S. Novikova, T. V. Popkova, A. N. Gerasimov, A. V. Volkov, E. L. Nasonov

“…To study relationship between heart rate (HR) and traditional risk factors for cardiovascular diseases (TRF for CVD), subclinical structural and functional changes in the heart and vessels, as well as the activity and severity of rheumatoid inflammation in women with rheumatoid arthritis (RA). Material and methods. A total of 291 female patients less than 60 years of age with a definite diagnosis of RA were examined. …”
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Comprehensive geriatric assessment-based screening and integrated intervention for osteosarcopenia risk factors in older adults: an application analysis in patients aged ≥80 years... by Tian ZHANG, Jiangming SHA, Liming JIANG, Quanzhong YIN, Yihang GU

“…Objective To explore the utility of comprehensive geriatric assessment (CGA) in screening risk factors for osteosarcopenia (OS) among older adults (≥80 years old) and to evaluate the therapeutic efficacy of CGA-guided integrated interventions for OS. MethodsA total of 420 patients aged ≥80 years, recruited from the Department of Geriatrics, General Practice of The Affiliated Jiangyin Hospital of Nantong University, and community health centers from January 2022 to October 2024, were enrolled. …”
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Migraine in men – differences in phenotype and treatment patterns: results from the Migraine in Poland cross-sectional national survey by Marta Waliszewska-Prosół, Karol Marschollek, Sławomir Budrewicz, Mieszko Więckiewicz, Magdalena Nowaczewska, Marcin Straburzyński

“…The purpose of this paper is to define migraine phenotype and patterns of care for Polish men. Methods Participants were recruited through various channels, primarily targeting individuals experiencing headaches. …”
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Emergence and evolution of rare ST592 blaNDM-1-positive carbapenem-resistant hypervirulent Klebsiella pneumoniae in China by Huan Zhang, Su Dong, Caiping Mao, Yuejuan Fang, Junjie Ying

“…ObjectivesThis study aimed to characterize the genomes of two rare ST592 Klebsiella pneumoniae isolates and to explore their evolution into carbapenem-resistant hypervirulent K. pneumoniae (CR-hvKp).MethodsThe minimum inhibitory concentrations (MICs) were determined using a VITEK 2 compact system. …”
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A Comparative Study of Sugammadex and Neostigmine: A Bibliometric Analysis of the Past 15 Years by Yin D, Tang B, Hu X, Hu H

“…Therefore, this study employed bibliometric analysis to map the evolutionary trajectory and research frontiers in sugammadex studies over the past 15 years.Methods: Publications on sugammadex (2009– 2024) along with neostigmine studies (1993– 2008) were retrieved from the Web of Science Core Collection. …”
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Interpretable machine learning analysis of environmental characteristics on bacillary dysentery in Sichuan Province by Yao Zhang, Qiao-Lin Wang, Wei Peng, Meng-Yuan Zhang, Yao Qin, Lun Zhang, Rong-Jie Wei, Dian-Ju Kang

“…However, a climate zone-specific predictive model for BD was currently lacking in Sichuan Province.ObjectiveThis study aims to employ interpretable machine learning to explore the influence of environmental factors on BD incidence across different climate zones and to elucidate their interaction mechanisms.MethodsMonthly data on meteorological and ecological factors, along with BD case reports, were collected from 183 counties in Sichuan Province (2005–2023). …”
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Effect of High Maintenance Dose Versus Low Dose of Remifentanil on Incidence of Postoperative Nausea and Vomiting (PONV) in Patients Under Gynecological Laparoscopic Procedure: A P... by Liu ZY, Yang XY, Lv C, Ye L, Chen JJ, Chen XY, Wang SP, Wu L, Zhang WQ, Lu M, Guo XW

“…Zao-Yu Liu,* Xin-Yu Yang,* Chen Lv, Ling Ye, Jia-Jia Chen, Xin-Yuan Chen, Shi-Ping Wang, Li Wu, Wei-Qiao Zhang, Man Lu, Xiao-Wen Guo Department of Anesthesiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xiao-Wen Guo, Department of Anesthesiology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, 310003, People’s Republic of China, Email guoxiaowen1315@hotmail.comPurpose: The aim of this trial was to investigate postoperative nausea and vomiting (PONV) incidence between low- and high-dose remifentanil with propofol for total intravenous anaesthesia (TIVA) in adult female patients with gynecologic laparoscopy.Patients and Methods: The randomized clinical trial consisted of two groups: 0.1ug/kg/min remifentanil (L group) (n=39) and 0.4ug/kg/min remifentanil (H group) (n=40). …”
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Age-Related Differences in the Appetite-Regulating Hormone Response to Exercise by Christoph Höchsmann, Hyeon Jung Heselton, Safiya E Beckford, Jeffrey A French, Jeffrey R Stevens, James L Dorling, Julie B Boron, Karsten Koehler

“…Objectives: We aimed to examine age-related differences in the effect of acute exercise on appetite-regulating hormones. Methods: Participants from 2 age cohorts (younger adults, 19–29 y, n = 39; older adults, 65–75 y, n = 29) completed 2 45-min study conditions on separate days in randomized order: 1) an exercise bout (60% V̇O2peak) on a bicycle ergometer (Exercise), and 2) a seated rest period (Rest). …”
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The Chain Mediating Effect of Health Literacy and Self-Care Ability on the Relationship Between Dysmenorrhea Symptoms and Negative Emotions Among Chinese Female College Students by Luo Y, Liu D, Sun G, Lu Y, Fang M, Zhang Y, Xu C, Bai G, Chen C

“…This study aims to assess the current status of dysmenorrhea and negative emotions among female college students and explore the factors influencing the relationship between menstrual pain and negative emotions.Methods: A total of 1,117 female college students with moderate to severe dysmenorrhea (based on a Visual Analog Scale (VAS) ≥ 4) were recruited from five universities in Guangdong Province through purposive and convenience sampling to complete an online survey between August and October 2024. …”
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Efficacy of virtual reality balance training on rehabilitation outcomes following anterior cruciate ligament reconstruction: A systematic review and meta-analysis. by Chao Du, Nei-Meng Gu, Tian-Ci Guo, Ai-Feng Liu

“…<h4>Objective</h4>The objective of this systematic review and meta-analysis is to clarify the rehabilitation efficacy of virtual reality (VR) balance training after anterior cruciate ligament reconstruction (ACLR).<h4>Methods</h4>This meta-analysis was registered in PROSPERO with the registration number CRD42024520383. …”
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Random Forest Regression May Become the Optimal Regression Model for Osteoarthritis of the Knee in Elderly, in the Context of Embodied Cognition and Psychosomatic Medicine by Ma G, Chen J, Li J, Shi H, Chen Y

“…Psychological and physical metrics included the Visual Analog Scale (VAS), Beck Anxiety Inventory (BAI), Geriatric Depression Scale (GDS), and Pittsburgh Sleep Quality Index (PSQI). …”
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Did COVID-19 surveillance system sensitivity change after Omicron? a retrospective observational study in England by Julii Brainard, Iain R. Lake, Roger A. Morbey, Alex J. Elliot, Paul R. Hunter

“…However, surveillance sensitivity may have changed as different variants were introduced to the population, due to greater disease-resistance after comprehensive vaccination programmes and widespread natural infection or for other reasons. Methods Time series data from ten epidemic trackers in England that were available Sept 2021-June 2022 were compared to each other using Spearman correlation statistics. …”
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Association of Risk-Taking Behaviors, Vestibular Provocation and Action Boundary Perception Following Sport-Related Concussion in Adolescents by Shawn R. Eagle, Anthony P. Kontos, Shawn D. Flanagan, Christopher Connaboy

“…<b>Background/Objectives</b>: The purpose of this study was to evaluate the association between risk-taking behaviors, vestibular symptoms/impairment and perception–action coupling behavior in recently concussed adolescents. <b>Methods</b>: This study utilized a cross-sectional design to evaluate the early effects of concussion on 12–18-year-old adolescents (n = 47) recruited from a concussion specialty clinic at their presenting clinical appointment. …”
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Impact of General Anesthesia and Antioxidants on Cognitive, Static and Locomotor Functions During Laparoscopic Cholecystectomy by V. V. Moroz, V. T. Dolgikh, S. A. Karpitskaya

“…Aim of the study: to reduce cognitive impairment during laparoscopic cholecystectomy by perioperative administration of drugs with antihypoxic and antioxidant effects under the control of stabilography.   Materials and methods. We studied the effect of general anesthesia and antioxidants on cognitive, static and locomotor functions during laparoscopic cholecystectomy. …”
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Accessibility of Massive Open Online Courses in Computer Sciences and Programming for Persons with Disabilities by E. A. Kosova, A S. Gapon, K. I. Redkokosh

“…At the same time, the specifics of online courses on programming require greater attention to the web content accessibility for persons with disabilities, especially in a program code.Material and methods. The selection of MOOCs was carried out in July 2020 by browsing catalogs of platforms with Russian-language content. …”
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Ultrasound-Guided Sural Nerve and Tibial Nerve Block Provides Comparable Analgesia to Popliteal Sciatic Nerve Block Following Calcaneal Surgery: A Single Center Randomized Controll... by Yao J, Cai J, Lu Q, Huang X

“…This study compared the efficacy of ultrasound-guided sural and tibial nerve blocks (ST) with popliteal sciatic nerve block (PS) for operative and postoperative analgesia.Methods: A total of 80 patients (40 per group) undergoing calcaneal surgery were randomized to receive either ST or PS nerve blocks. …”
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