Polymorphisms of the KCNS1, COMT and OPRM1 genes and development of postoperative pain in patients with osteoarthritis who underwent total knee or hip replacement by K. E. Glemba, I. A. Guseva, A. E. Karateev, M. A. Makarov, E. Yu. Samarkina, N. V. Konovalova, D. A. Varlamov

“…The search for predictors of postoperative pain is an actual problem.The aim of the study – to assessing relationship the polymorphisms of the KCNS1, COMT and OPRM1 genes and the development of POP in OA patients who underwent TKA or THA.Material and methods. The study group consisted of 95 patients with OA knee or hip (64.6% of women, 65.4±9.0 years) who underwent TKA (47.8%) or THA (52.2%). …”
Get full text

Nice knots assistance in comminuted and displaced clavicle fractures reduce intraoperative blood and shorten operation time with a satisfactory postoperative clinical outcome by Chao Li, Weiwei Cao, Jinlei Dong, Lianxin Li, Lin Li, Huailin Kou, Fanxiao Liu

“…Abstract Background This study aims to evaluate the efficacy and clinical outcomes of Nice knot-assisted fixation in the management of comminuted and displaced clavicle fractures. Methods A systematic search was conducted across multiple electronic databases, including PubMed, Embase, Cochrane Library, China Biology Medicine (CBM) database, CNKI, Wanfang, and VIP database, to identify studies comparing Nice knot-assisted fixation with traditional surgical treatment for displaced midshaft clavicle fractures. …”
Get full text

Prevalence and factors associated with fertility desire among people living with HIV: A systematic review and meta-analysis. by Xiang Yan, Jie Du, GuoPing Ji

“…However, there are many studies among which the association remains controversial between the fertility desire of HIV-infected persons and antiretroviral therapy (ART), sex, marital status, and educational level.<h4>Methods</h4>We performed a literature search of these meta-analyses in PubMed, the Cochrane Library, Web of Science and ScienceDirect in November 2019. …”
Get full text

Effect of DMARD Therapy on Inflammatory Biomarkers and Disease Activity in Rheumatoid Arthritis Patients by Hardik Kharbanda, Manish Khanna, Krunal Thakrar, Manojit Basak, Manish Dwivedi, Partha Pratim Das

“…Objectives: The aim of this study is to evaluate the impact of DMARD therapy on inflammatory biomarkers and disease activity indices in patients with RA. Materials and Methods: The study aims to evaluate and compare pre- and post-therapy outcomes retrospectively of patients with seropositive and seronegative RA undergoing DMARD therapy. …”
Get full text

A Comparative Study of Short-Term Social Media Use with Face-to-Face Interaction in Adolescence by Inês Mendonça, Franz Coelho, Belén Rando, Ana Maria Abreu

“…This study aimed to examine the short-term cognitive effects of acute social media exposure and screen time habits by comparing cognitive performance in adolescents (13–15 years old) following 30 min of social media interaction versus face-to-face conversation, according to their screen time habits (more or less time spent in front of a screen). Methods: A total of 66 participants were divided into four groups: a social media group who used to spend less than 540 min per week in front of a screen (<i>n</i> = 19, a social media group with a habit of more than 540 min per week of screen time (<i>n</i> = 14), a face-to-face conversation group with a habit of less screen time per week (<i>n</i> = 15), and a face-to-face conversation group who used to spend more time per week in front of a screen (<i>n</i> = 18). …”
Get full text

Cold Atmospheric Plasma Improves the Therapeutic Success of Photodynamic Therapy on UV-B-Induced Squamous Cell Carcinoma in Hairless Mice by Stephanie Arndt, Petra Unger, Irina Ivanova, Wolfgang Bäumler, Konstantin Drexler, Mark Berneburg, Sigrid Karrer

“…The present study investigated the effects of combining CAP with ALA-PDT on cutaneous AK and SCC induced by ultraviolet B (UV-B) irradiation in SKH1 hairless mice. <b>Methods:</b> We compared various application sequences (CAP-ALA–red light, ALA–red light–CAP, and ALA-CAP–red light) against conventional ALA-PDT using visual, histological, and molecular assessments of the affected skin. …”
Get full text

Modified Supraclavicular and Pectoral Nerves Blocks for Implantation of Intravenous Port System in Cancer Patients by M. P. Yakovenko, E. E. Antipin, N. A. Bochkareva, N. I. Koroleva, E. F. Drobotova, E. V. Nedashkovsky

“…Ultrasound-guided regional anesthesia can be an effective way to achieve analgesia during implantation of permanent intravenous port systems.The aim of the study was to improve the quality of perioperative analgesia during placement of permanent intravenous port systems.Material and methods. The prospective randomized study included 93 patients with malignant neoplasms. …”
Get full text

Effects of aerobic exercise in addition to core stabilization exercises on functional capacity, physical performance and fall risk in geriatric individuals with chronic non-specifi... by Şafak Kuzu, Mehmet Canli, İrem Valamur, Anıl Özüdoğru, Halil Alkan, Abdulmetin Hartavi

“…The aim of our study was to compare the effects of core stabilization exercises alone and aerobic exercises in addition to core stabilization exercises on functional capacity, physical performance and fall risk in geriatric individuals with chronic non-specific low back pain (CNLBP). Methods In this randomized controlled study, 30 participants in the core stabilization exercise group (CG) received intervention, and the mean age of this group was 70.43 ± 4.48 years. …”
Get full text

Platelet-rich Plasma versus Corticosteroid Injection for the Treatment of Lateral Epicondylitis – A Prospective Randomised Controlled Study by Suryakanth Kalluraya, Anand Varma, Gujjala Venkata Naga Yeswanth

“…Settings and Design: This was a prospective randomised controlled study. Materials and Methods: This study was a prospective randomised control trial of 100 patients, clinically diagnosed with lateral epicondylitis in Karnataka Institute of Medical Sciences Hospital, Hubli. …”
Get full text

Percentage macular ganglion cell complex and peripapillary retinal nerve fiber layer loss in different stages of glaucoma by Shah Zalak, Sihota Ramanjit, Sen Ray Swarnali, Choudhary Samiksha, Dhillon Jasleen

“…As only the eyes of the same patient with different severities of glaucoma were included in the present study, it could be inferred that the difference in parameters represents the loss leading to the next stage of glaucoma. Methods: This was a cross-sectional study of 136 adult primary glaucoma eyes of 68 patients. …”
Get full text

The association between sleep duration and myopia among Chinese school-age students: mediation effect of physical activity by Haiqing Feng, Yuexia Gao, Na An, Yitong Lu, Jianping Huang, Weiping Yang, Qingyun Lu

“…BackgroundThis study aimed to investigate the relationship between sleep duration and myopia in school-age students, as well as to observe the role of physical activity as a mediating variable in sleep duration and myopia.MethodsUsing multistage stratified sampling, 26,020 school-age students in Jiangsu Province, ages 7–18, were selected for this cross-sectional survey. …”
Get full text

Optimizing Virtual Follow-Up Care: Realist Evaluation of Experiences and Perspectives of Patients With Breast and Prostate Cancer by Sarah Scruton, Geoff Wong, Stephanie Babinski, Lauren R Squires, Alejandro Berlin, Julie Easley, Sharon McGee, Ken Noel, Danielle Rodin, Jonathan Sussman, Robin Urquhart, Jacqueline L Bender

“…ObjectiveThis study aims to examine how, for whom, and in what contexts VFU works for cancer survivorship care. MethodsWe conducted a realist evaluation of VFU among patients with breast cancer and prostate cancer at an urban cancer center during the COVID-19 pandemic. …”
Get full text

Study protocol for a Prospective Observational study of Safety Threats and Adverse events in Trauma (PrO-STAT): a pilot study at a level-1 trauma centre in Canada by Melissa McGowan, Charles Keown-Stoneman, Brodie Nolan, Teodor Grantcharov, Eliane M Shore, Anisa Nazir

“…Insights from this evaluation will inform targeted interventions to improve procedural adherence, communication and overall team performance, ultimately reducing preventable errors and improving patient safety.Methods and analysis A prospective observational study will be conducted at St. …”
Get full text

Clinical outcomes following medial meniscus posterior root repairs: A minimum of 5‐year follow‐up study by Yuki Okazaki, Kazuhisa Sugiu, Yusuke Kamatsuki, Masanori Tamura, Koki Kawada, Tsubasa Hasegawa, Takayuki Furumatsu

“…Abstract Purpose This study assessed the clinical outcomes of the FasT‐Fix dependent modified Mason‐Allen suture (F‐MMA) and two simple stitches (TSS) on mid‐term postoperative outcomes following medial meniscus (MM) posterior root repair. Methods Forty‐three patients who underwent transtibial pullout repair for MM posterior root tear (PRT) between November 2016 and September 2018 were initially enrolled. …”
Get full text

Comparison of the donor site healing following free gingival graft procedure with and without topically applied ozonated oil as wound dressing by Kalaiselvan Dharani, P.T. Priyangha

“…Aim: The present study aimed to compare and assess the wound healing efficacy of topically applied ozonated oil in palatal wounds following a free gingival graft (FGG) procedure. Materials and Methods: A total of 10 patients were selected and randomly assigned to control or test groups. …”
Get full text

The Two Sides of Placebo Analgesia: Differential Functional Connectivity Reveals Mechanisms of Placebo Analgesic Response by Bush NJ, Cushnie AK, Boissoneault J, Aghabeigi S, Alexander C, Staud R, Robinson ME

“…However, despite robust research characterizing these effects, individual differences in predicting placebo analgesic responses are not well understood.Methods: Fifty-four healthy pain-free adults over 18 (M=22.8, SD=7.82) were recruited (66.7% women). …”
Get full text

Screening of necroptosis-related genes and evaluating the prognostic capacity, clinical value, and the effect of their copy number variations in acute myeloid leukemia by Dake Wen, Ru Yan, Lin Zhang, Haoyang Zhang, Xuyang Chen, Jian Zhou

“…Here, we evaluated the diagnostic ability, prognostic capacity of necroptosis-related genes (NRGs) and the effect of their copy number variations (CNVs) in AML. Methods Necroptosis-related differentially expressed genes (NRDEGs) were identified after intersecting differentially expressed genes (DEGs) from the Gene Expression Omnibus(GEO) database with NRGs from GeneCards, the Molecular Signatures Database (MSigDB) and literatures. …”
Get full text

The Effectiveness of Topical Treatment for Plantar Warts: A Retrospective Cohort Study by Ana Mª Rayo Pérez, José María Juárez Jiménez, Rafael Rayo Rosado, Raquel García de la Peña

“…<b>Objectives</b>: We aimed to evaluate and compare the clinical efficacy, post-treatment pain, and patient satisfaction among three common treatments (zinc and nitric complex, cantharidin, and bleomycin) in subjects with plantar warts, as well as identify the most effective and best-tolerated treatment. <b>Materials and Methods</b>: This is a retrospective case series study analyzing 60 records of subjects aged 18 to 40 years diagnosed with plantar warts without systemic diseases or allergies and without any prior treatment. …”
Get full text

Oblique lateral internal fusion combined with percutaneous pedicle screw fixation in severe lumbar spinal stenosis: clinical and radiographic outcome by Chen Liu, Yin Geng, Yifeng Li

“…Herein, we investigated the clinical and radiographic outcome of OLIF with percutaneous pedicle screws in the treatment of severe lumbar spinal stenosis. Methods A total of 15 patients who underwent OLIF with percutaneous pedicle screws were retrospectively analysed. …”
Get full text

Meta-analysis on effects of lymphatic drainage techniques in the management of carpal tunnel syndrome by Sina Shahshenas, Hossein Yarmohammadi, Masood Soltanipur, Zahra Sheikhi

“…This study aimed to evaluate the effects of lymphatic drainage techniques on symptom severity, functional outcomes, nerve conduction parameters, and pain relief in patients with CTS. Methods This meta-analysis was conducted following PRISMA guidelines. …”
Get full text