The efficacy and safety of pilates exercise in patients with knee osteoarthritis: a systematic review with meta-analysis of randomized controlled trials by Kuayue Zhang, Yuan Li, Fanying Zhao, Xiaoming Xie, Shaoshuai Yan, Deming Kong, Wenshuo Zhang, Jun Zhou, Haoning Ma

“…This meta-analysis aimed to evaluate its efficacy and safety.Methods We searched PubMed, Web of Science, EMBASE, Cochrane Library, and Google Scholar up to May 21, 2024, for randomized controlled trials (RCTs). …”
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An innovative minimally invasive technique for lumbar adjacent segment disease: a retrospective comparative analysis between extreme-oblique lumbar interbody fusion combined with p... by Xiuqi Shan, Jilong An, Liang Li, Yapeng Sun, Jiaqi Li, Fei Zhang, Lei Guo, Wei Zhang

“…Abstract Purpose This study evaluates An Innovative Minimally Invasive Technique using extreme-oblique lumbar interbody fusion combined with percutaneous endoscopic lumbar discectomy (XOLIF + PELD) versus posterior lumbar interbody fusion (PLIF) for lumbar adjacent segment disease(ASD) treatment. Methods We retrospectively analyzed 58 patients (26 treated with the combined technique, 32 with posterior fusion) with minimum 24-month follow-up. …”
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Adding thread-embedding acupuncture to auricular acupuncture enhances short-term weight reduction in overweight and obesity: A double-blinded, randomized, sham-controlled trial by Dieu-Thuong Thi Trinh, Quoc-Viet Kieu, An Hoa Tran, Minh-Man Pham Bui, Nguyen Lam Vuong

“…This study was conducted to address this question. Methods: A randomized placebo-controlled trial was conducted involving 66 overweight or obese participants, divided into two groups: 33 received AA plus TEA, and 33 received AA plus sham TEA over eight weeks. …”
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Global hotspots and trends in pre-metastatic niche research: a bibliometric analysis(2005-2024) by Mengqi Cheng, Mengqi Cheng, Qianhui Sun, Qianhui Sun, Hua Duan, Hua Duan, Cihui Chen, Cihui Chen

“…This study aims to identify global research trends and hotspots in PMN through a systematic bibliometric evaluation, providing a foundation for future advancements in this field.MethodsPublications related to PMN research from 2005 to 2024 were retrieved from the Web of Science Core Collection database. …”
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ARTIFICIAL INTELLIGENCE TOOLS IN TEACHING SOCIAL AND HUMANITARIAN DISCIPLINES by Anna Kyrpa, Olena Stepanenko, Viktoriia Zinchenko, Tetiana Datsiuk, Iryna Karpan, Neonila Tilniak

“…This encourages the evaluation and development of new methods that provide a personalized approach to teaching and learning, including integration of artificial intelligence (AI) tools that can revolutionize education. …”
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Integrated bioinformatics analysis of the crucial candidate genes and pathways associated with glucocorticoid resistance in acute lymphoblastic leukemia by Yanxin Chen, Peifang Jiang, Jingjing Wen, Zhengjun Wu, Jiazheng Li, Yuwen Chen, Lingyan Wang, Donghui Gan, Yingyu Chen, Ting Yang, Minhui Lin, Jianda Hu

“…In this study, we used bioinformatic analysis methods to integrate the candidate genes and pathways participating in GC resistance in ALL and subsequently verified the bioinformatics findings with in vitro cell experiments. …”
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Optimization of Fermentation Conditions for Endophytic Fungi from <i>Schisandra chinensis</i> and Investigation of Their Antibacterial Mechanisms Against Methicillin-Resistant <i>S... by Mengyu Li, Yuewei Shi, Wenwei Ma, Shouyuan Cai, Xinyuan Yang, Lukai Xu, Xiyan Hou, Lulu Wang, Liming Jin, Chunshan Quan

“…Methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) is a highly pathogenic bacterium for which safe and effective prevention as well as treatment methods are currently lacking. In this study, <i>Rhizoctonia bicornis</i> S10 was isolated from <i>Schisandra chinensis</i> and used to inhibit MRSA. …”
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MultiAgency, prospective, exploratory, non-intervention, cohort Study on Human Impact Exposure oNboard high-speed boats (MASHIEN): protocol by Stephen D Myers, Ola Rolfson, Yohan Robinson, Spyros D Masouros, John J Fraser, Yann Daniel, Johan Ullman, Kai-Thorsten Bretschneider, Karen R Kelly, Victor Hurpin, Justus Kaehler, Jan Ivar Kåsin, Knut Hveding, Neil Mansfield, Daniel Perl, Nicole Wijnands, Isabelle Vallee, Veerle Stevens

“…The MultiAgency, prospective, exploratory, non-intervention, cohort Study on Human Impact Exposure oNboard high-speed boats study aims to investigate the nature and magnitude of these impacts, their acute and long-term health effects, and potential injury prevention strategies to improve operational safety and performance.Methods and analysis This is an ongoing multicentre, prospective, non-intervention, observational cohort study. …”
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Immunohistochemical Expression of Haptoglobin in Skin Lesions of Hidradenitis Suppurativa by Nessr Abu Rached, Hanna Telkemeyer, Marina Skrygan, Martin Doerler, Yannik Haven, Lennart Ocker, Daniel Myszkowski, Thomas Meyer, Markus Stücker, Eggert Stockfleth, Falk G. Bechara

“…This study examines the relationship between haptoglobin expression in HS skin lesions and clinical parameters. Methods: An examination was performed on 44 skin samples from HS patients and 10 healthy skin samples. …”
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Cell graph analysis in hepatocellular carcinoma: predicting local recurrence and identifying spatial relationship biomarkers by Yizhe Yuan, Ziyin Zhao, Xin Fang, Qing Zhang, Wenqing Zhong, Midie Xu, Gongqi Li, Rushi Jiao, Heng Yu, Ruoxi Wang, Shuyu Liu, Weitao Zu, Bingsen Xue, Yuze Chen, Chengxiang Wang, Ya Zhang, Minghui Liang, Bing Han, Cheng Jin

“…The proposed HGTs outperformed existing SOTA methods, with the C-index improving by 23.1% to reach 0.823, by further integrating multimodal data, including clinical information and immunohistochemical markers. …”
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Determinants of academic performance of healthcare professional students in a medical university, Ajman, United Arab Emirates by Shahnaz Mohamed Wazil, Sathyapriya Nandagopal, Afreen Abdul Rahim Sanaullah, Liju Susan Mathew, Nermine Nosseir, Jayadevan Sreedharan, Jayadevan Sreedharan, Anusha Sreejith, Anusha Sreejith, Latifa Nabeel Alsaad, Latifa Nabeel Alsaad, Jayakumary Muttappallymyalil, Jayakumary Muttappallymyalil

“…Understanding these contributing factors is essential for supporting student success and optimizing educational outcomes.MethodsA cross-sectional study was conducted among 521 healthcare professional students aged 18 and above using a self-administered questionnaire. …”
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The network and interactive pattern of social adjustment and psychological symptoms in patients with spinal cord injury: a network analysis by Hui Liu, Yi Ni, Haixia Xie, Yijun Xie, Chenhui Fan, Yao Li, Weinan Shen, Hua Zhai, Chenghua Jiang, Jing Wu, Hengjing Wu

“…Objective To determine the network structure and interaction patterns of social adjustment and psychological symptoms in patients with spinal cord injury (SCI). Methods A cross-sectional patient-reported study was conducted using an online questionnaire survey disseminated from February to April 2023. …”
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Efficacy and safety of interferon-alpha 1b injection into the intervertebral foramen with ultrasonic guidance in patients with postherpetic neuralgia: study protocol for a randomiz... by Hui-Min Hu, Hui-Min Hu, Wen-Hui Liu, Wen-Hui Liu, Chen Li, Chen Li, Qing Shi, Qing Shi, Chun-Hua Liu, Chun-Hua Liu, An-Xiang Liu, An-Xiang Liu, Yi-Fan Li, Yi Zhang, Peng Mao, Bi-Fa Fan

“…In this study, we aim to evaluate the efficacy and safety of interferon (IFN)-α1b injection into the intervertebral foramen of patients with PHN.Patients and methodsThis is a study protocol for a randomized, double-blind placebo-controlled multicenter clinical trial. …”
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Use and meaning teachers assign to the integration of the MICA 3.0 kit for teaching climate change by Sonia Pino, César Cofre, Humberto Vergara, Luis Vergara, Jaime Solís-Pinilla, Andoni Arenas-Martija, Andoni Arenas-Martija, Andoni Arenas-Martija, Paulina Ampuero, Paulina Ampuero, Cristian Merino, Cristian Merino

“…IntroductionTeaching climate change requires teachers to have the educational resources that will facilitate teaching this content and visualize how a global problem has various local implications. …”
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Low-dose RaDiation therapy for patients with KNee osteoArthritis (LoRD-KNeA): a protocol for a sham-controlled randomised trial by Jiyu Sun, Won Park, Dong Hyun Kim, Ji Hyun Lee, Joon Ho Wang, Hak Jae Kim, Kichul Shin, Min Jung Kim, Ji Young Kim, Byoung Hyuck Kim, Du Hyun Ro, Dae-Hee Lee, Eun-Hee Hong, Seong-Jun Cho, Hyuk-Soo Han

“…The presented trial aims to evaluate the efficacy and safety of LDRT for patients with knee OA.Methods and analysis This prospective, multicentre, randomised trial will be conducted in the Republic of Korea. …”
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Distinguishing features of microvascular abnormalities in high myopia retinoschisis via multimodal imaging by Yunhan Tao, Xuhui Chen, Tao Li, Xian Zhang, Xufang Sun

“…Purpose: To report the differences between microvascular abnormalities (MVAs) and retinal vasculitis in patients with high myopia (HM) and retinoschisis and discuss the efficacy of treatments, including corticosteroids, and posterior vitreous detachment (PVD). Methods: We enrolled seven patients with HM retinoschisis in the Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology. …”
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Effect of seasonal exposure in aeroallergen-sensitised patients with irritable bowel syndrome-diarrhoea by Carlo Maria Rossi, Carlo Maria Rossi, Marco Vincenzo Lenti, Marco Vincenzo Lenti, Stefania Merli, Martina Fiorita, Martina Fiorita, Antonio Lo Bello, Antonio Lo Bello, Mario Andrea Latorre, Mario Andrea Latorre, Paola Ilaria Bianchi, Nicola Aronico, Annalisa De Silvestri, Antonio Di Sabatino, Antonio Di Sabatino

“…BackgroundPollen allergy may influence irritable bowel syndrome (IBS) symptoms; however, available data are scant.AimsThis study aims to assess symptom variability in atopic IBS patients.MethodsWe retrospectively analysed consecutive adult IBS patients evaluated between 2021 and 2024. …”
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Quantifying the spatial patterns of retinal ganglion cell loss and progression in optic neuropathy by applying a deep learning variational autoencoder approach to optical coherence... by Jui-Kai Wang, Jui-Kai Wang, Brett A. Johnson, Zhi Chen, Zhi Chen, Honghai Zhang, Honghai Zhang, David Szanto, Brian Woods, Brian Woods, Michael Wall, Young H. Kwon, Young H. Kwon, Edward F. Linton, Edward F. Linton, Andrew Pouw, Mark J. Kupersmith, Mark J. Kupersmith, Mark J. Kupersmith, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Mona K. Garvin, Randy H. Kardon, Randy H. Kardon

“…Furthermore, the bVAE model is capable of tracking the spatial pattern of RGC thinning over time and classifying the underlying cause.MethodsThe bVAE model consists of an encoder, a display decoder, and a booster decoder. …”
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Gender-specific association of STON2 rs2371597 polymorphism in keratoconus patients of Saudi origin by Altaf A. Kondkar, Altaf A. Kondkar, Altaf A. Kondkar, Tahira Sultan, Taif A. Azad, Tanvir Khatlani, Glenn P. Lobo, Hatem Kalantan, Saleh A. Al-Obeidan, Saleh A. Al-Obeidan, Abdulrahman M. Al-Muammar

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Retinal ganglion cell repopulation for vision restoration in optic neuropathy: a roadmap from the RReSTORe Consortium by Jonathan R. Soucy, Erika A. Aguzzi, Julie Cho, Michael James Gilhooley, Casey Keuthan, Ziming Luo, Aboozar Monavarfeshani, Meher A. Saleem, Xue-Wei Wang, Juilette Wohlschlegel, The RReSTORe Consortium, Petr Baranov, Adriana Di Polo, Brad Fortune, Kimberly K. Gokoffski, Jeffrey L. Goldberg, William Guido, Alex L. Kolodkin, Carol A. Mason, Yvonne Ou, Thomas A. Reh, Ahmara G. Ross, Brian C. Samuels, Derek Welsbie, Donald J. Zack, Thomas V. Johnson

“…The RGC Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration (RReSTORe) Consortium was established to address the challenges associated with the therapeutic repair of the visual pathway in optic neuropathy. In 2022, the RReSTORe Consortium initiated ongoing international collaborative discussions to advance the RGC repopulation field and has identified five critical areas of focus: (1) RGC development and differentiation, (2) Transplantation methods and models, (3) RGC survival, maturation, and host interactions, (4) Inner retinal wiring, and (5) Eye-to-brain connectivity. …”
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