The efficacy of low-level laser therapy in oral surgery: A systematic review of randomized controlled trials by Alain Chaple Gil, Leonardo Díaz, Alfredo Von Marttens, Claudio Sotomayor, Javier Basualdo, Víctor Beltrán, Gilbert Jorquera, Rodrigo Caviedes, Eduardo Fernández

“…It also aimed to identify optimal laser parameters for future clinical application. Methods: A systematic review of randomized controlled trials (RCTs) was performed following PRISMA 2020 guidelines and the PROPS framework. …”
Get full text

Pretreatment with transcutaneous electrical acupoint stimulation to prevent postoperative ileus in patients undergoing laparoscopic colon surgery: study protocol for a randomised c... by Wei Song, Rui Feng, Lihua Fan, Jun Guo, Dongli Li, Wenting Chen, Yue Yong, Guijie Yu, Lan Yuan, Guoqiang Fu, Jiangang Song

“…This trial will evaluate the effects of pretreatment with TEAS on POI.Methods and analysis This will be a prospective, randomised controlled trial. …”
Get full text

Microwave ablation for subpleural stage I non-small cell lung cancer: a prospective, single-center study comparing three anesthesia models by Yu-Feng Wang, ZhiXin Bie, YuanMing Li, Sheng Xu, RunQi Guo, Xiao-Guang Li

“…Objectives To compare the analgesic efficacy and safety of three anesthetic techniques during microwave ablation (MWA) for subpleural stage I non-small cell lung cancer (NSCLC).Materials and Methods This prospective, single-center clinical trial enrolled patients with subpleural stage I NSCLC between January 2024 and December 2024. …”
Get full text

Presence of Potential Enteropathogenic Bacteria in Cats and Association With Diarrhea in Multicat Households by Kirsten Bogedale, Ute Klein‐Richers, Sandra Felten, Michèle Bergmann, Nikola Pantchev, Yury Zablotski, Jan Suchodolski, Kathrin Busch, Stefan Unterer, Katrin Hartmann

“…Animals In total, 234 cats from 41 privately owned catteries were included. Methods In this prospective study, feces were evaluated for consistency according to a visual scoring system (Purina Fecal Score). …”
Get full text

Using Key Predictors in an SVM Model for Differentiating Spinal Fractures and Herniated Intervertebral Discs in Preoperative Anesthesia Evaluation by Shih-Ying Yang, Shih-Yen Hsu, Yi-Kai Su, Nan-Han Lu, Kuo-Ying Liu, Tai-Been Chen, Kon-Ning Chiu, Yung-Hui Huang, Li-Ren Yeh

“…Accurate differentiation between these conditions is crucial for effective treatment, particularly in the context of preoperative anesthesia evaluation, where understanding the underlying condition can influence anesthesia planning and pain management. <b>Methods and Materials:</b> This study presents a Support Vector Machine (SVM) model designed to distinguish between spinal fractures and HIVDs using key clinical predictors, including age, gender, preoperative Visual Analog Scale (VAS) pain scores, and the number of spinal fractures. …”
Get full text

‘It Just Makes Sense to Me’: A qualitative study exploring patient decision‐making and experiences with prostate MRI during active surveillance for prostate cancer by Ryan Sutherland, Cary P. Gross, Xiaomei Ma, Farah Jeong, Tyler M. Seibert, Matthew R. Cooperberg, William J. Catalona, Shellie D. Ellis, Stacy Loeb, Dena Schulman‐Green, Michael S. Leapman

“…Abstract Introduction Although prostate magnetic resonance imaging (MRI) is commonly used in the diagnosis, staging and active surveillance of prostate cancer, little is known about patient perspectives on MRI. Methods We performed a qualitative study consisting of in‐depth, semi‐structured interviews of patients with low‐ and intermediate‐risk prostate cancer managed with active surveillance. …”
Get full text

Comparative analysis of upper body postural angles and their association with neck pain in car and motorcycle drivers by Aafreen Aafreen, Abdur Raheem Khan, Ashfaque Khan, Ausaf Ahmad, Monira I. Aldhahi, Weam Okab Alsalem, Mohammed M Alshehri, Almutasim Billa Moafa, Ahmed Ghazwani, Mohammad Abu Shaphe

“…Purpose: This study aimed to assess upper-body postural angles and neck pain among car drivers and motorcycle drivers separately, and to compare these outcomes between the two groups. Methods: This cross-sectional study comprised a total of 200 participants, with an equal distribution between car drivers (n = 100) and motorcycle drivers (n = 100). …”
Get full text

Learning a Foreign Language in Older Adults Shapes the Functional Connectivity of Distinct Cerebellar Sub‐Regions With Cortical Areas Rich in CB1 Receptor Expression by Giovanna Bubbico, Federica Tomaiuolo, Carlo Sestieri, Golnoush Akhlaghipour, Alberto Granzotto, Antonio Ferretti, Mauro Gianni Perrucci, Stefano L. Sensi, Stefano Delli Pizzi

“…We hypothesize that FLL primarily modulates the rs‐FC of the most “cognitive” cerebellar sub‐regions, such as the crus and the posterior lobules. Methods The rs‐FC pattern was analyzed in 27 participants who underwent a 4‐week FLL (n = 14) or a control (n = 13) protocol. …”
Get full text

Identification of Crucial Genes Associated With MYCN‐Driven Neuroblastoma Based on Single‐Cell Analysis and Machine Learning by Jiasi Zhang, Yichen Lei, Yaqin Wang, Wen Yu, Xiaoyan Zhao, Yongbing Zhu, Dedong Zhang, Siying Liu, Aiguo Liu

“…Elucidating these pathways is critical for advancing personalized treatments for MYCN‐driven NB. Methods We performed single‐cell transcriptomic analysis comparing NB samples with and without MYCN. …”
Get full text

Risk factors for biometry prediction error by Barrett Universal II intraocular lens formula in Chinese patients by Xu-Hao Chen, Ying Hong, Xiang-Han Ke, Si-Jia Song, Yu-Jie Cen, Chun Zhang

“…AIM: To investigate the influence of postoperative intraocular lens (IOL) positions on the accuracy of cataract surgery and examine the predictive factors of postoperative biometry prediction errors using the Barrett Universal II (BUII) IOL formula for calculation. METHODS: The prospective study included patients who had undergone cataract surgery performed by a single surgeon from June 2020 to April 2022. …”
Get full text

Identification of key pathways and molecular players potentially involved in endometrial cancer metastasis through integrated bioinformatics analyses by Maryam Rezazadeh, Shahla Danaei-Mehrabad, Nahideh Afshar Zakariya, Fatemeh Kazemi, Marziyeh Sadat Moslehian, Amin Tamadon, Reza Shirazi, Mahdi Mahdipour, Parvin Hakimi

“…This study aimed to identify new important molecular actors and clarify the molecular processes and pathways underlying EC metastasis. Methods: The GEOexplorer and R programming languages were used to analyze and visualize gene expression data from EC metastatic gene expression datasets, and differentially expressed genes (DEGs) and differentially expressed lncRNAs (DElncRNAs) were identified using bioinformatics with P-value thresholds of < 0.05, and |log2FC| > 1.5. …”
Get full text

Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research by Rossitza Draganova, Genisius Hartanto, Robert Jan Pawlik, Jana Luisa Aulenkamp, Jana Luisa Aulenkamp, Sigrid Elsenbruch, Sigrid Elsenbruch

“…We investigated responses to the experience of pain from the visceral (rectal distension) and somatic (cutaneous heat) pain modalities, with a focus on elucidating sex differences in EGG and HRV responses.MethodsIn a sample of healthy volunteers (29 males, 43 females), EGG and ECG data were collected during a baseline and a pain phase. …”
Get full text

Separating Subjective from Objective Food Value in the Human Insula: An Exploratory Study Using Intracranial EEG by Benjamin Hébert-Seropian, Olivier Boucher, Daphné Citherlet, Manon Robert, François Richer, Dang Khoa Nguyen

“…To address this gap, we conducted an exploratory study using an intracranial EEG (iEEG) to investigate how the insula encodes both the subjective and objective properties of food-related stimuli, and how this encoding is modulated by hunger and satiety. <b>Methods</b>: Eight patients with drug-resistant epilepsy undergoing a pre-surgical evaluation between 2017 and 2023 participated in this study. …”
Get full text

Individualized resting-state functional connectivity abnormalities unveil two major depressive disorder subtypes with contrasting abnormal patterns of abnormality by Keke Fang, Lianjie Niu, Baohong Wen, Liang Liu, Ya Tian, Huiting Yang, Ying Hou, Shaoqiang Han, Xianfu Sun, Wenzhou Zhang

“…However, the clinical heterogeneity, likely stemming from diverse neurobiological disturbances, complicates findings from standard group comparison methods. This variability has driven the search for MDD subtypes using objective neuroimaging markers. …”
Get full text

ICT-Net: An Integrated Convolution and Transformer-Based Network for Complex Liver and Liver Tumor Region Segmentation by Chukwuemeka Clinton Atabansi, Hui Li, Sheng Wang, Jing Nie, Haijun Liu, Bo Xu, Xichuan Zhou, Dewei Li

“…However, two major challenges remain: 1) existing models struggle to extract robust spatial features for accurate liver and liver lesion segmentation, and 2) publicly available liver datasets with HCC annotations are limited. Methods: We first present a new liver dataset acquired from Chongqing University Cancer Hospital (CCH-LHCC-CT) with HCC annotations. …”
Get full text

Cognitive and motor disturbances in depression: insights from comprehensive behavioral assessments by Ioanna Douka, Marit F. L. Ruitenberg, Marit F. L. Ruitenberg, Kamile Weischedel, Carlos Phouthavongsay, Sara L. Weisenbach, Jos N. van der Geest, Brian J. Mickey, Vincent Koppelmans

“…However, comprehensive assessments of cognitive and motor domains in the same depression sample are rare.MethodsThis pilot study compared 20 depressed patients and 22 controls across multiple tests of cognitive and motor functions. …”
Get full text

Advancing 1.5T MR imaging: toward achieving 3T quality through deep learning super-resolution techniques by Sk Rahatul Jannat, Kirsten Lynch, Maryam Fotouhi, Steve Cen, Steve Cen, Jeiran Choupan, Nasim Sheikh-Bahaei, Nasim Sheikh-Bahaei, Gaurav Pandey, Bino A. Varghese

“…These factors impact heterogeneity in MRI neuroimaging data on account of the uneven distribution of 1.5T and 3T MRI scanners across healthcare institutions.MethodsIn our study, we investigated the efficacy of three deep learning-based super-resolution techniques to enhance 1.5T MRI images, aiming to achieve quality analogous to 3T scans. …”
Get full text

First Report on Rigid Plate Fixation for Enhanced Sternal Closure in Minimally Invasive Cardiac Surgery: Safety and Outcomes by Jules Miazza, Benedikt Reuthebuch, Florian Bruehlmeier, Ulisse Camponovo, Rory Maguire, Luca Koechlin, Ion Vasiloi, Brigitta Gahl, Luise Vöhringer, Oliver Reuthebuch, Friedrich Eckstein, David Santer

“…Introduction: This study reports of the use of a rigid-plate fixation (RPF) system designed for sternal closure after minimally invasive cardiac surgery (MICS). Methods: This retrospective analysis included all patients undergoing MICS with RPF (Zimmer Biomet, Jacksonville, FL, USA) at our institution. …”
Get full text

Examining Brain Function Changes in HIV‐Infected Patients With Asymptomatic Neurocognitive Impairment: A Longitudinal Study by Juming Ma, Zhongkai Zhou, Shuai Han, Chuanke Hou, Xingyuan Jiang, Fan Xu, Haixia Luo, Jiaojiao Liu, Wei Wang, Haiyan Zhao, Lingling Zhao, Hongjun Li

“…Resting‐state functional magnetic resonance imaging (rs‐fMRI) focusing on ANI among HIV‐related patients is rarely reported. Methods 60 right‐handed Chinese male patients with HIV‐associated ANI underwent baseline and follow‐up neurocognitive examination, and rs‐fMRI scans over an average interval of 1.68 years. …”
Get full text

Comparing Clinical Efficacy between Minimally Invasive Osteotomy and Weil Osteotomy for Treatment of Metatarsalgia by Zixing Bai, Xuhan Cao, Yanjun Yang, Chengyi Sun, Si Chen, Haiwei Hu, Jianmin Wen, Xinxiao Lin, Weidong Sun

“…Aim and objective: To investigate the differences of indications and clinical efficacy between the minimally invasive osteotomy and the Weil osteotomy for treatment of the metatarsalgia. Materials and methods: One hundred and four metatarsal bones in 64 feet of 51 patients with mild metatarsalgia were divided into two groups. …”
Get full text