Effect of icatibant on sweating-induced dermal pain by Shunsuke Takahagi, Shunsuke Takahagi, Daiki Matsubara, Emi Murakami, Yumi Aoyama, Shinya Imamura, Atsushi Fukunaga, Atsushi Fukunaga, Yoshiko Oda, Hiroyuki Murota, Michihiro Hide, Michihiro Hide

“…This study aimed to evaluate the analgesic effect of icatibant, a bradykinin B2 receptor antagonist, for the dermal pain induced by sweating stimuli and explored the role of bradykinin in its pathomechanism.MethodsThis single-blind, randomized, crossover study enrolled adult patients who had experienced severe sweating-induced dermal pain. …”
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The Micro-Structure of the Celiac Ganglia—A Two-Photon Microscopy Study on Parkinson’s Disease by Diana-Theodora Morgos, Lucian-George Eftimie, Horia Nicolae, Remus Iulian Nica, Constantin Stefani, Daniela Miricescu, Radu Hristu, George A. Stanciu, Adrian Tulin, Florin Filipoiu

“…SHG specifically allows detailed imaging of collagen fibers and neuronal structures, revealing alterations in collagen density and organization that correlate with dysautonomia. <b>Methods</b>: The cross-sectional study was conducted at “Dr. …”
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Multi-Channel Multi-Protocol Quantum Key Distribution System for Secure Image Transmission in Healthcare by Bandana Mallick, Priyadarsan Parida, Chittaranjan Nayak, Tarek Khalifa, Manoj Kumar Panda, Nawaf Ali, Gajanan Uttam Patil, Bibhu Prasad

“…To address the limitations of existing methods in securing electronic medical records, we have explored an encryption technique using a set of real-time medical images along with existing standard images using QKD protocols including BB84 (Bennett-Brassard 1984), CASCADE (Cascading Error Correction Algorithm for Data Exchange), and differential-phase-shift (DPS) under the fiber-based (OFC) and free-space (FSO) channels. …”
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Large models in medical imaging: Advances and prospects by Mengjie Fang, Zipei Wang, Sitian Pan, Xin Feng, Yunpeng Zhao, Dongzhi Hou, Ling Wu, Xuebin Xie, Xu-Yao Zhang, Jie Tian, Di Dong, Yuanyuan Ji

“…This review summarizes the concepts, methods, and progress of large models in medical imaging, highlighting their potential in precision medicine. …”
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Clinical efficacy of myometrial and endometrial microwave ablation in the treatment of patients with adenomyosis who had anemia by Zuolin Li, Xiaolian Li, Min Lin, Sihua Qiu, Liangqin Wang, Liping Lai, Xuefen Luo, Zunyu Mo, Gang Dong, Guorong Lyu, Shuiping Li

“…Objective This study evaluated the clinical efficacy of myometrial and endometrial microwave ablation (MEWA) for treating adenomyosis in patients with anemia.Methods This retrospective study enrolled 64 patients with adenomyosis who had anemia treated with either MEWA (MEWA group) or myometrial microwave ablation (MMWA group) between May 2019 and May 2021. …”
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Thelaziasis in humans: A systematic review of reported cases by D. Katterine Bonilla-Aldana, Jorge Luis Bonilla-Aldana, Jaime David Acosta-España, Ranjit Sah, Alfonso J. Rodriguez-Morales

“…Human thelaziasis remains underreported and poorly understood in many regions despite its growing relevance. Methods: This systematic review analyzed epidemiological, clinical, diagnostic, and therapeutic data from 134 documented human cases of thelaziasis reported across 18 countries. …”
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Global trends and research hotspots in the treatment of mental disorders with transcranial magnetic stimulation: a bibliometric analysis by Zong-ke Ma, Zong-ke Ma, Yi-xin Wei, Yi-xin Wei, Ling Rao, Ling Rao, Bao-jin Li, Bao-jin Li, Qiang Gao, Qiang Gao

“…The exploration and expanding application of various new TMS mode have significantly propelled the advancement of related clinical research.MethodsWe reviewed research published in the Science Citation Index Expanded of Web of Science Core Collection database. …”
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Temporomandibular Internal Derangements Denote Activity of Axial Spondyloarthritis by Ana-Marija Laškarin, Stjepan Špalj, Gordana Laskarin, Antonija Ružić Baršić, Jasmina Grđan, Emina Babarović, Tatjana Kehler, Viktor Peršić, Nikša Dulčić

“…This study aimed to investigate SpA activity in patients with ID of TMJ. Materials and Methods: We assessed 200 patients with neck pain using the Assessment of Spondyloarthritis International Society (ASAS) criteria. …”
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Current research status and trends of potassium-competitive acid blockers in the treatment of acid-related diseases: a bibliometric analysis by Baoqiang Zhu, Long Chen, Xue Tao, Hong Zheng, Xia Li, Qingfang Wu, Enwu Long, Haixia Lin

“…ObjectiveTo explore the current research status and trends of potassium-competitive acid blockers (P-CABs) in the treatment of acid related diseases (ARDs) using bibliometric analysis.Materials and methodsWe collected publications related to P-CAB in the treatment of acid-related diseases in the Web of Science (WOS) Core Collection from the establishment of the database to 30 June 2024. …”
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Treatment of thoracolumbar fractures with severe collapse of the anterior and middle columns via balloon-assisted endplate reduction, transpedicular bone grafting and pedicle screw... by Hai-qiang Shen, Yun-qin Xu, You-rong Yao, Qi Liu, Lin-ying Zhou, Xiao-jie Chen, Xiao-hong Lu, Xing Zhao, Yong Tang

“…Therefore, we evaluated the effectiveness of balloon-assisted endplate reduction (BAER), transpedicular bone grafting, and pedicle screw fixation for this type of thoracolumbar fracture. Methods This retrospective study included 87 patients with thoracolumbar fractures involving severe collapse of the anterior and middle columns treated from January 2020 to January 2022. …”
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Anti-VEGF treatment switch in real-world DME patients: ranibizumab versus aflibercept for bevacizumab DME non-responding patients (SWIRL study) by Yu Qiang Soh, Zheng Xian Thng, Wei Kiong Ngo, Colin S Tan, Tock Han Lim, Louis W Lim, Augustinus Laude, Darren Choy, Wen Jun Song, Helen Fang Mi, Koh Lilian, Jacob Yu Hang Chin, Karen Jhi Wen Chia, Issac Too, Nicola Y Gan, Rajesh Rajagopalan

“…Background/aims To describe the functional outcomes of patients with diabetic macular oedema (DME) non-responsive to bevacizumab switched to ranibizumab or aflibercept over 1 year and the demographic and anatomic predictors of these functional outcomes.Methods In a retrospective real-world cohort study, 76 consecutive patients with DME non-responsive to bevacizumab were reviewed at baseline and 12 months after switch to ranibizumab or aflibercept. …”
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Efficacy and safety of herbal medicine (Dangguijagyag-san) for primary dysmenorrhea: study protocol for a randomized, double-blind, placebo-controlled, parallel-group, multi-center... by Hye Lin Woo, Hae Ri Ji, Siin Kim, Hae Sun Suh, Kwan-Il Kim, Jin Moo Lee, Kyoung Sun Park

“…The purpose of this trial is to evaluate the efficacy and safety of the herbal medicine, Dangguijagyag-san, relative to those of active control, Gamisoyo-san, and a placebo control for primary dysmenorrhea. Methods: This protocol details a randomized, double-blind, parallel-group, multi-center, investigator-initiated, controlled trial evaluating treatment of primary dysmenorrhea. …”
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Integrated bulk and single-cell RNA sequencing reveals a cuproptosis-related LncRNA prognostic signature in neuroblastoma by Ke Chen, Jing Wang, Shimin Yang, Jun Xiao, Luyao Wu, Zejian Li, Xiang Zhao, Xuyong Chen, Honglin Li, Jiexiong Feng, Xinyao Meng

“…While cuproptosis has emerged as a critical regulator in oncobiology, its mechanistic involvement in NB remains poorly characterized. Methods RNA-seq data of NB patients was analyzed using limma and ClusterProfiler. …”
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Twelve-Month Follow-Up of Dexamethasone Implants for Macular Edema from Various Diseases in Vitrectomized and Nonvitrectomized Eyes by Eduardo A. Novais, Mauricio Maia, Paulo Augusto de Arruda Mello Filho, João Rafael de Oliveira Dias, José Maurício B. B. Garcia, Gabriel C. de Andrade, Ricardo N. Louzada, Marcos Ávila, André Maia, J. Fernando Arevalo, Lihteh Wu, Maria Berrocal, Emmerson Badaró, Michel Farah

“…Methods. This multicenter retrospective cohort study included 112 patients with CME secondary to retinal diseases treated pro re nata (PRN) with a 0.7 mg intravitreal dexamethasone implant for 12 months. …”
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5HT2A Receptors are Involved in the Pharmaco-Toxicological Effects of the Synthetic Cannabinoids JWH-018 and 5F-PB22: in Vivo Studies in Mice by G. Corli, M. Tirri, T. Bernardi, F. Boccuto, M. Borsari, M. Bassi, S. Bilel, M. Marti

“…Thus, this study aims to evaluate the involvement of 5HT2A receptors in the effects provoked by these substances. Methods: The effects induced by acute systemic administration of 1-pentyl-3-(1-naphthoyl)indole (JWH-018; 1 mg/kg) and quinolin-8-yl 1-pentyfluoro-1H-indole-3-8-carboxylate (5F-PB22; 1 mg/kg) on sensorimotor (visual, acoustic and tactile) responses, pain threshold (acute mechanical and thermal nociception), core temperature, breath rate and motor performance (stepping activity), as well as their interaction with the selective 5HT2A receptors antagonist MDL100907 (0.1 mg/kg), have been evaluated in CD-1 male mice. …”
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Bleaching efficacy of in-office bleaching with violet light using low-concentration hydrogen peroxide nanoparticulate photocatalyst gel: A randomized controlled trial by Gustavo Garcia Castro, Palena Araújo Pinto, Michael Willian Favoreto, Alessandra Reis, Maria Viviana-Mora, Rita de Cássia Mendonça de Miranda, Andres Felipe Milan Cardenas, Alessandro D. Loguercio, Rudys Rodolfo de Jesus Tavarez

“…The risk and intensity of TS were recorded using a 0–10 visual analogue scale (VAS) and a 0–4 numerical scale (NRS). …”
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STIED: a deep learning model for the spatiotemporal detection of focal interictal epileptiform discharges with MEG by Raquel Fernández-Martín, Alfonso Gijón, Odile Feys, Elodie Juvené, Alec Aeby, Charline Urbain, Xavier De Tiège, Vincent Wens

“…Automatic, data-driven detection methods exist but show limited performance. Still, the rise of deep learning (DL)—with its ability to reproduce human-like abilities—could revolutionize clinical MEG practice. …”
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Predicting risk factors for Epstein-Barr virus reactivation using Bayesian network analysis: a population-based study of high-risk areas for nasopharyngeal cancer by Zhiwen Zeng, Kena Lin, Xueqi Li, Xueqi Li, Tong Li, Xiaoman Li, Jiayi Li, Zule Ning, Qinxian Liu, Shanghang Xie, Sumei Cao, Sumei Cao, Jinlin Du

“…This study aimed to investigate the risk factors for EBV reactivation associated with NPC in high-prevalence areas in China using a Bayesian network (BN) model combined with structural equation modeling tools.MethodsThe baseline information for this study was derived from NPC screening data from a population-based prospective cohort in Sihui City, Guangdong Province, China. …”
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Efficacy of single vision spectacles combined with low-level red-light therapy in myopic amblyopia for children aged 4-8 by Lin Li, Ya Liao, Wei Wang, Yinghui Xiong, Qin Li, Lin Zhang, Xiaojuan Wang

“…Purpose: This study evaluated the efficacy and safety of Low-Level Red Light(LLRL) therapy for improving amblyopia and controlling myopia in children aged 4-8 years with myopic amblyopia. Methods: A prospective clinical trial with 66 children, conducted from September 2023 to May 2024, included those with Spherical Equivalent Refraction (SER = sphere power + ½ cylinder power) ≤ -0.50 D and astigmatism ≤ 2.50 D, excluding pathological myopia cases. …”
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Rapid-onset neovascular glaucoma following cataract surgery in diabetes: outcomes of pars plana vitrectomy combined with Ahmed glaucoma valve implantation by Hui-Ping Yao, Ya-Nuo Wang, Yan-Wei Chen, Sha Gao, Yi-Sheng Zhong, Xi Shen

“…AIM: To present a case series of rapid-onset neovascular glaucoma (NVG) accompanied by vitreous haemorrhage (VH) following cataract surgery in diabetic patients, and to evaluate the efficacy of pars plana vitrectomy (PPV) combined with Ahmed glaucoma valve (AGV) implantation. METHODS: This is a retrospective, single-center, consecutive case series. …”
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