Fundus changes in healthy adults after high altitude exposure by Jiaxin Li, Yunzhu Kong, Peiyu Wang, Chen Chen, Juping Liu, Xiaorong Li, Yan Shao

“…The aim is to provide a reference for the prevention and treatment of high altitude ophthalmopathy. Methods: 30 eyes of 15 healthy participants exposed to high altitude were recruited in this study. …”
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Single-row arthroscopic rotator cuff repair improves functional outcomes at a minimum follow-up of 3 years by Hastomo A. Wibowo, MD, Iman W. Aminata, MD, Andri M.T. Lubis, MD, PhD, Indah S. Widyahening, MD, PhD, Achmad F. Kamal, MD, PhD, Aryadi Kurniawan, MD, PhD, Ismail H. Dilogo, MD, PhD, Wahyu Widodo, MD, Thomas Erwin C.J. Huwae, MD, PhD, Renaldi P.N. Rasyid, MD, PhD, Oryza Satria, MD, Dina Aprilya, MD, Ali R. Alkaff, MD

“…Background: To evaluate patients who underwent arthroscopic rotator cuff repair (ARCR) using a single-row technique and compare functional outcomes before and after surgery at a minimum follow-up of 3 years. Methods: This retrospective cohort study reviewed the functional outcomes of 38 patients who underwent ARCR with a single-row technique between 2015 and 2020 with a minimum follow-up of 3 years. …”
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Media Role of Graphic in Harmonizing The Meanings Association Pattern with Forms of Expression and Literacy Genre by Amir Reza Estakhrian Haghighi, Setareh Ahsant

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Patient participation in free cataract surgery: a cross-sectional study of the low-income elderly in urban China by Bo Qu, Hui Chen, Xuhua Tan, Xiaohang Wu, Haotian Lin, Zhenzhen Liu, Lixia Luo, Bo Zhang, Erping Long, Duoru Lin, Weirong Chen, Yizhi Liu, Haofeng Jiang, Jingjing Chen, Zhuoling Lin, Xiaoyan Li, Jinzhu Tang, Yingfen Lin

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Metformin inhibits pathological retinal neovascularization but promotes retinal fibrosis in experimental neovascular age-related macular degeneration by Xin Wang, Xin Wang, Xu Liang, Shiya Huang, Mingyan Wei, Yuan Xu, Xiaodong Chen, Yanliang Miao, Rongrong Zong, Xiang Lin, Shiying Li, Zuguo Liu, Zuguo Liu, Qian Chen, Qian Chen

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Cytokine profile of intraocular fluids to predict macular edema in surgical treatment of rhegmatogenous retinal detachment by I.V. Khizhnyak, E.V. Boiko, I.E. Panova, A.N. Trunov, E.M. Svistunova, Yu. P. Koval’chuk

“…Based on the study of cytokines content in the vitreous body and subsilicone fluid (SSF), to evaluate risk factors for the development of macular edema in patients with rhegmatogenous retinal detachment (RRD) after endovitreal surgery. Material and methods. An analysis of the treatment of 28 patients (28 eyes) with RRD complicated by PVR Sr type 1–4 involving the macular area was carried out. …”
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Assessing the neurological impact of vitamin B12 deficiency among the population of Riyadh, Saudi Arabia by Khalid A. Bin Abdulrahman, Abdulelah F. Alshehri, Faisal Marzouq Almutairi, Faisal Ali Almahyawi, Rayan Saleh Alzahrani, Osama Thamer Al-Ahmari, Khalid Alshammari, Turki Ahmed Aljuhani, Yazeed Yahya Alkadi, Mohammed Atiah Alisi

“…BackgroundVitamin B12 (cobalamin) deficiency can cause anemia, peripheral neuropathy, visual impairment and irreversible neurological damage. …”
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Regional homogeneity patterns reveal the genetic and neurobiological basis of State-Trait Anxiety by Yuanhao Li, Su Yan, Jia Li, Yuanyuan Qin, Li Li, Nanxi Shen, Yan Xie, Dong Liu, Jicheng Fang, Tian Tian, Wenzhen Zhu

“…However, the genetic and neurobiological basis of anxiety-related functional changes remain largely unknown. Methods Participants aged 18–30 from the community underwent resting-state fMRI and were assessed with the State-Trait Anxiety Inventory. …”
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Bibliometric mapping of diabetes mellitus and sarcopenia research: hotspots and emerging trends by Min Wang, Qiyang Zhou, Xinyu Guo, Xiaolong Cui, Zhongquan Tang, Ting Ou, Xiaomin Zhao, Chen Liang, Peiyu Xu, Xinyu Dai, Jingqing Yao, Guozhong Ji, Yuntao Li

“…This study pioneers a bibliometric analysis to systematically investigate their association, aiming to map the knowledge structure, evolutionary trajectories, current foci, and emerging frontiers within this area.MethodsWe retrieved 2,773 publications from the Web of Science Core Collection from inception until December 26, 2024, and visual analyses were conducted using CiteSpace, VOSviewer, R, and Microsoft Excel. …”
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AI-based Assessment of Risk Factors for Coronary Heart Disease in Patients With Diabetes Mellitus and Construction of a Prediction Model for a Treatment Regimen by Zhen Gao, Qiyuan Bai, Mingyu Wei, Hao Chen, Yan Yan, Jiahao Mao, Xiangzhi Kong, Yang Yu

“…The SHAP algorithm also provided clear explanations and visualizations of the model's predictions. …”
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The relationship between the CYP2C19*17 genetic polymorphism and the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome by V. Yu. Skryabin, M. S. Zastrozhin, E. A. Grishina, K. A. Ryzhikova, V. V. Shipitsyn, I. V. Barna, T. E. Galaktionova, A. S. Sorokin, E. A. Bryun, D. A. Sychev

“…The aim of our study was to study the relationship between the CYP2C19 genetic polymorphism and the efficacy and safety of diazepam in patients with alcohol withdrawal syndrome in order to develop algorithms for optimizing the therapy of diazepam to reduce the risk of dose-dependent adverse drug reactions and pharmacoresistance.Materials and methods. The study was conducted on 30 Russian male patients suffering from alcohol withdrawal syndrome. …”
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Development of a Recombinase Polymerase Amplification-Coupled CRISPR/Cas12a Platform for Rapid Detection of Antimicrobial-Resistant Genes in Carbapenem-Resistant <i>Enterobacterale... by Ji Woo Yang, Heesu Kim, Lee-Sang Hyeon, Jung Sik Yoo, Sangrim Kang

“…Traditional diagnostic methods are often too slow and complex for rapid point-of-care testing. …”
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Thoracic duct drainage patterns in heterotaxy by Daniel A. Castellanos, Emily M. Bucholz, Katherine Bai, Jesse J. Esch, David Hoganson, Stephen P. Sanders, Raja Shaikh, Sunil J. Ghelani, David N. Schidlow

“…This study sought to describe terminal TD sidedness in heterotaxy and its associations with other anatomic variables. Methods: This was a retrospective, single-center study of patients with heterotaxy who underwent cardiovascular magnetic resonance imaging at a single center between July 1, 2019 and May 15, 2023. …”
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Geospatial impact evaluation of a low-cost agricultural intervention for enhancing environmental resilience by Pratap Khattri, Rachel Sayers, Kunwar K. Singh, Ryan Slapikas, Chet Bahadur Tamang, Dinee Tamang, Brad Sagara, Ariel BenYishay

“…We assessed the causal impact of a program promoting sugarcane farming on its adoption and environmental outcomes, measured using multi-temporal satellite imagery, crop phenology, and clustering algorithms, along with machine learning and visual interpretation methods. Our results show that sugarcane adoption increased significantly in both treated and spillover communities, highlighting its potential as a sustainable agricultural practice. …”
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<i>Acinetobacter baumannii</i> Co-Resistant to Extended Spectrum Beta-Lactamases and Carbapenemases in Six Peruvian Hospital Centers by Mabel R. Challapa-Mamani, José Yareta, Alexander Fajardo-Loyola, Percy Asmat Marrufo, Carlos Peralta Siesquen, Jimena Pino-Dueñas, Henry Meza-Fernández, Jhony A. De La Cruz-Vargas, Pool Marcos-Carbajal

“…Objectives: The aim of this study was to describe the phenotypic and molecular characteristics of <i>Acinetobacter baumannii</i> isolates carrying resistance genes to beta-lactams and carbapenems in six Peruvian public hospital centers. Materials and methods: The susceptibility of bacterial isolates was determined using the automated MicroScan system, with interpretation according to the M100 S30 CLSI 2020. …”
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Deep learning empowered sensor fusion boosts infant movement classification by Tomas Kulvicius, Dajie Zhang, Luise Poustka, Sven Bölte, Lennart Jahn, Sarah Flügge, Marc Kraft, Markus Zweckstetter, Karin Nielsen-Saines, Florentin Wörgötter, Peter B. Marschik

“…These approaches are hardly comparable as all models are designed, trained and evaluated on proprietary/silo-data sets. Methods With this study we propose a sensor fusion approach for assessing fidgety movements (FMs). …”
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Trio-based whole-exome sequencing reveals mutations in early-onset high myopia by Ding Chen, Xiu-Feng Huang, Juan Huang, Yi-Ming Guo, Junhan Wei, Lu Ye, Yi-Xin Cai, Jiejing Bi, Fen-Fen Li

“…Purpose Myopia, especially high myopia (HM), represents a widespread visual impairment with a globally escalating prevalence. …”
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Robotic sympathetic trunk reconstruction for compensatory sweating after thoracic sympathectomyCentral MessageProspective by Lisa Wen-Yu Chen, MD, Tommy Nai-Jen Chang, MD, Chin-Pang Lee, MD, Cheyenne Wei-Hsuan Sung, MD, Chuan Cheng, MD, Kuo-Hsuan Chang, MD, PhD, Yin-Kai Chao, MD, PhD

“…The objective of this case series is to report the 2-year outcomes after robotic sympathetic trunk reconstruction (STR) for the reversal of CS in patients who had undergone endoscopic thoracic sympathectomy. Methods: We prospectively followed-up a total of 23 patients who had undergone robotic STR because of intolerable CS between October 2017 and January 2021. …”
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Identification of variants in SWI/SNF complex genes associated with neurodevelopmental disorders by Chen Liang, Chen Liang, Haihong Shi, Yanjuan Chen, Xia Wang, Jieyuan Jin, Liqun Su, Lijun Tang, Huihong Li, Fei Ling, Haoxian Li, Yanghui Zhang, Yanghui Zhang

“…ARID2, ARID1B, and SMARCC2 are important subunits of the SWI/SNF complex, and their variants can also result in Coffin-Siris syndrome (CSS), a type of NDDs characterized by CNS disorders, global developmental delay, visual/hearing impairment, distinct facial features, and congenital heart disease (CHD).MethodsThree NDDs families were recruited, and whole-exome sequencing and Sanger sequencing were used to detected their causative variant.ResultsWe described their symptoms and identified three variants of SWI/SNF complex genes unreported in disease cohorts, including a deletion variant of ARID2 (NM_152641: c.2901delC, p.Asn967LysfsX2), an insertion variant of ARID1B (NM_001374828: c.6532_6533insT, p.Trp2178LeufsX34), and a missense variant of SMARCC2 (NM_003075: c.2920C&gt;G, p.Pro974Ala). …”
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Oxylipins in Aqueous Humor of Primary Open-Angle Glaucoma Patients by Jianming Xu, Kewen Zhou, Changzhen Fu, Chong-Bo Chen, Yaru Sun, Xin Wen, Luxi Yang, Tsz-Kin Ng, Qingping Liu, Mingzhi Zhang

“…Purpose: Investigate the oxylipin profiles in the aqueous humor of primary open-angle glaucoma (POAG) patients. Methods: Aqueous humor samples were collected from 17 POAG patients and 15 cataract subjects and subjected to a liquid chromatography/mass spectrometry (LC-MS) analysis to detect the oxylipins. …”
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