Optimising neonatal services for very preterm births between 27+0 and 31+6 weeks gestation in England: the OPTI-PREM mixed-methods study by Thillagavathie Pillay, Oliver Rivero-Arias, Natalie Armstrong, Sarah E Seaton, Miaoqing Yang, Victor L Banda, Kelvin Dawson, Abdul QT Ismail, Vasiliki Bountziouka, Caroline Cupit, Alexis Paton, Bradley N Manktelow, Elizabeth S Draper, Neena Modi, Helen E Campbell, Elaine M Boyle

Get full text

From the Editor-in-Chief by Valery A. Sokolov

“…The key principles of software-configured networks are separation of data transfer and data management, centralization of network management using unified software, virtualization of physical network resources.Subjects of the conference reflected the following areas:- construction of modern computer networks;- service virtualization in SDN;- applications of modern network technologies;- organization of cloud computing;- applications of cloud technologies.The conference Program Committee includes leading scientists and developers from more than 10 countries of the world. …”
Get full text

Ring Tension, Hydrocarbon Acidity, and New «Super-Bases» by Manfred Schlosser, Jürgen Hartmann, Manfred Stähle, Jaroslav Kramař, Annelies Walde, Alessandro Mordini

“…On the other hand, cyclobutanes were found to be virtually inert towards alcoholate-activated pentylsodium. …”
Get full text

Ligand Based Multi-Targeted Molecular Docking Analysis o f Terpenoid Phytoconstituents as Potential Chemotherapeutic Agents Against Breast Cancer: An In Silico Approach by Senthil Kumar Raju, Shridharshini Kumar, Praveen Sekar, Naveena Sundhararajan, Yogadharshini Nagalingam

“…Finally, 73 compounds, which showed anti-breast cancer activity prediction, were virtually screened and the top four best-scoring compounds were selected as lead-like molecules and docked with the five respective breast cancer targets. …”
Get full text

Scanning by DOVAM-S Detects All Unique Sequence Changes in Blinded Analyses: Evidence that the Scanning Conditions Are Generic by C.H. Buzin, C.Y. Wen, V.Q. Nguyen, G. Nozari, A. Mengos, X. Li, J.S. Chen, Q. Liu, R.A. Gatti, F.K. Fujimura, S.S. Sommer

“…The [detection of virtually all mutations]-SSCP (DOVAM-S) is a highly sensitive variant of single strand conformation polymorphism (SSCP). …”
Get full text

FIRM ATTRIBUTES AND PROFIT MANIPULATION AGGREGATE AMONG QUOTED NIGERIAN INDUSTRIAL COMPANIES by Samson Oyewole OLABISI

“… Evidence has shown that earnings management (EM) is an endemic problem present in virtually all countries of the world. Most importantly, the effect of firm attributes on EM activities cannot be over-emphasized. …”
Get full text

A Role for PPAR𝛽/𝛿 in Ocular Angiogenesis by David Bishop-Bailey

“…The uses of highly selective PPAR𝛽/𝛿 ligands and PPAR𝛽/𝛿 knockout mice have shown a direct ability of PPAR𝛽/𝛿 to regulate angiogenesis in vitro and in vivo in animal models. …”
Get full text

Topography Pre-Treatment of Laser-Textured Surfaces for Friction Simulation in AVL Excite by Gábor Laki, László Boros, András Lajos Nagy

“…The aim of this study is to understand how selected surface pre-processing (pre-treatment) steps affect the calculations. …”
Get full text

The human visual system differentially represents subjectively and objectively invisible stimuli. by Timo Stein, Daniel Kaiser, Johannes J Fahrenfort, Simon van Gaal

“…For objectively invisible stimuli, however, category information remained virtually unchanged from early visual cortex to object- and category-selective visual areas. …”
Get full text

Investigating Natural Product Inhibitors of IKKα: Insights from Integrative In Silico and Experimental Validation by Muhammad Yasir, Jinyoung Park, Eun-Taek Han, Jin-Hee Han, Won Sun Park, Jongseon Choe, Wanjoo Chun

“…This study investigates the potential of selectively targeting IKKα to develop novel therapeutic strategies. …”
Get full text

NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas by Priyanka Sehgal, Ammar S. Naqvi, Makenna Higgins, Jiageng Liu, Kyra Harvey, Julien Jarroux, Taewoo Kim, Berk Mankaliye, Pamela Mishra, Grace Watterson, Justyn Fine, Jacinta Davis, Katharina E. Hayer, Annette Castro, Adanna Mogbo, Charles Drummer, 4th, Daniel Martinez, Mateusz P. Koptyra, Zhiwei Ang, Kai Wang, Alvin Farrel, Mathieu Quesnel-Vallieres, Yoseph Barash, Jamie B. Spangler, Jo Lynne Rokita, Adam C. Resnick, Hagen U. Tilgner, Thomas De Raedt, Daniel J. Powell, Jr., Andrei Thomas-Tikhonenko

“…Thus, pHGG-specific NRCAM and possibly other L1-IgCAM proteoforms are promising and highly selective targets for adoptive immunotherapies.…”
Get full text

Leadership Approaches in Public Owned Industrial Organisations: Evidence from a Developing Country by Z. Mannan

“…Sixty management personnel were systematically selected from three distinct manufacturing organisations for the study. …”
Get full text

The effect of automated accounting systems (AAS) on audit independence: Empirical Evidence from South West, Nigeria. by Amos Olusola AKINOLA, Adekunle Olusola OLADEJO, Ebenezer Foluso OLUWAKAYODE, Abud-Azeez Adetunji ADEREMI

“…A cross-sectional survey design with primary data sourced through a structured questionnaire drawn on four Likert scales and a total of 514 copies of the questionnaire physically/virtually administered to auditors (randomly selected) in private engagement in six states of South West, Nigeria.  362 valid questionnaires were descriptively analysed using percentages and mean. …”
Get full text

Talent management practices for minimising talent turnover in a public sector organisation by Edith E. Gandi, Musawenkosi D. Saurombe

“…Semi-structured interviews were conducted among 14 employees at the selected public sector organisation both virtually and in person. …”
Get full text

Augmented Reality in Higher Education: A Systematic Review and Meta-Analysis of the Literature from 2000 to 2023 by Gege Li, Heng Luo, Di Chen, Peiyu Wang, Xin Yin, Jiakai Zhang

“…Augmented reality (AR) has been widely used in higher education because of its unique characteristics that combine virtuality and reality. This study systematically reviewed the literature on the application of AR in higher education between 2000 and 2023. …”
Get full text

Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's disease. by Sydney R Coffey, Robert M Bragg, Shawn Minnig, Seth A Ament, Jeffrey P Cantle, Anne Glickenhaus, Daniel Shelnut, José M Carrillo, Dominic D Shuttleworth, Julie-Anne Rodier, Kimihiro Noguchi, C Frank Bennett, Nathan D Price, Holly B Kordasiewicz, Jeffrey B Carroll

“…Despite this selective neuropathology, the mutant protein (huntingtin) is found in virtually every cell so far studied, and, consequently, phenotypes are observed in a wide range of organ systems both inside and outside the central nervous system. …”
Get full text

History and Philosophy of Sustainable Development: Road-Mapping Interdisciplinarity for Wellbeing by Akeem Amodu

“…Sustainable development finds mention in virtually every conceivable discipline and endeavour: medicine, literature, politics, community development, globalisation and deep ecology, among others. …”
Get full text

Case Report: Exploring the spectrum of A20 haploinsufficiency in children by Sahana Jayaraman, Nayimisha Balmuri

“…Tailored therapies were selected to match the dominant inflammatory pathway and produced durable clinical remission in all cases. …”
Get full text

Plasmon-driven molecular scission by Wang Hui

“…Plasmon-driven bond cleavage in molecular adsorbates represents a critical step in virtually all plasmon-mediated photocatalytic reactions and has been identified as the rate-determining step in many cases. …”
Get full text

Dynamical Core in Atmospheric Model Does Matter in the Simulation of Arctic Climate by Sang‐Yoon Jun, Suk‐Jin Choi, Baek‐Min Kim

“…We emphasize that special attention is needed in selecting the dynamical core of climate models in the simulation of the Arctic climate and associated teleconnection patterns.…”
Get full text