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Exploring bioactive phytoconstituents as USP21 inhibitors for therapeutic development against cancer
Published 2025-05-01“…In the present study, an integrated virtual screening strategy was adopted using IMPPAT 2.0. database to identify bioactive phytoconstituents that can potentially inhibit USP21. …”
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543
Digital health interventions in reducing loneliness and improving mental health in older adults - a literature review
Published 2025-06-01“…Aim of the study: This review aims to evaluate existing literature on select digital health interventions in mitigating loneliness and improving mental well-being in the older population. …”
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544
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Computational identification of novel natural inhibitors against triple mutant DNA gyrase A in fluoroquinolone-resistant Salmonella Typhimurium
Published 2025-03-01“…Subsequently, a high-throughput virtual screening of a curated library of natural compounds was conducted to identify potential inhibitors against wild-type and triple-mutant proteins. …”
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546
Harnessing Natural Product Compounds to Target Dormancy Survival Regulator (DosR) in Latent Tuberculosis Infection (LTBI): An In Silico Strategy Against Dormancy
Published 2025-06-01“…Herein, the NP-lib database containing natural product compounds was screened virtually against the binding site of the DosR protein using the MTiopen screen web server. …”
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547
Chemical Space Exploration and Machine Learning-Based Screening of PDE7A Inhibitors
Published 2025-03-01Get full text
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548
Role of residual mandibular teeth after computer-assisted mandibular reconstruction using a fibular flap
Published 2024-12-01Get full text
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549
Insights Into Rapid Identification, Screening and Activity Investigation of Novel Hemp Seed Pancreatic Lipase/Cholesterol Esterase Inhibitory Peptides
Published 2025-05-01“…Subsequently, a combination of ultrafiltration, peptidomics, and virtual screening methods was employed for the rapid identification and screening of PL and CE inhibitory peptides. …”
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550
Qualitative analysis of negative and positive COVID-19 experiences of frontline client educators in a Canadian maritime province
Published 2025-01-01“…In a Canadian maritime province, we launched a longitudinal proof-of-concept study of a virtual-mental-health intervention to improve quality of life for members of a teachers' union. …”
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Selective Dual Inhibition of TNKS1 and CDK8 by TCS9725 Attenuates STAT1/β-Catenin/TGFβ1 Signaling in Renal Cancer
Published 2025-06-01“…Methods: To identify leads, the ChemBridge library was screening using high-throughput virtual screening (HTVS), which was followed by protein–ligand interaction analysis, Molecular Dynamics (MD) simulation, and Gibbs binding free energy estimation. …”
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553
Innovative Technologies in Physical Education and Their Impact on Developing Students Motor Skills: Systematic Literature Review
Published 2025-04-01“…Results: The findings revealed that virtual and augmented reality improved spatial awareness and coordination, while wearable devices enhanced self-regulation. …”
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554
Innovative Technologies in Physical Education and Their Impact on Developing Students Motor Skills: Systematic Literature Review
Published 2025-04-01“…Results: The findings revealed that virtual and augmented reality improved spatial awareness and coordination, while wearable devices enhanced self-regulation. …”
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555
Three-dimensional automatic artificial intelligence driven augmented-reality selective biopsy during nerve-sparing robot-assisted radical prostatectomy: A feasibility and accuracy...
Published 2023-10-01“…At the end of extirpative phase, thanks to our new AAR artificial intelligence driven system, the virtual prostate 3D model allowed to identify the tumour's location at the level of the preserved NVB and to perform a selective excisional biopsy, sparing the remaining portion of the bundle. …”
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556
Using innovative technology tools in organic chemistry education: bibliometric analysis
Published 2024-12-01“…This study focused on investigating the usage of popular innovative technology tools (augmented reality-AR, virtual reality-VR, artificial intelligence-AI, and 3D printing) in organic chemistry education. …”
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557
Acceptance and use of extended reality in surgical training: an umbrella review
Published 2024-12-01“…Abstract Background Extended reality (XR) technologies which include virtual, augmented, and mixed reality have significant potential in surgical training, because they can help to eliminate the limitations of traditional methods. …”
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558
Finite element modeling to predict procedural success of thoracic endovascular aortic repair in type A aortic dissectionCentral MessagePerspective
Published 2020-12-01“…The aim of this study is to explore and better understand biomechanical changes after TEVAR and predict the result via virtual stenting. Methods: A case of type A aortic dissection was considered inoperable and selected for TEVAR. …”
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559
A scoping review of the ethics frameworks describing issues related to the use of extended reality [version 2; peer review: 1 approved, 2 approved with reservations]
Published 2025-02-01“…The use of extended reality (XR) / immersive technologies such as virtual, augmented, mixed reality and virtual worlds (Metaverse) raises issues of ethical concern. …”
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560
Emerging Digital Technologies: Building Competencies of STEM Pre-Service Teachers
Published 2025-03-01Get full text
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