Direct Current (DC)-induced modulation of lipid metabolism and intercellular vesicular trafficking on a neuroblastoma in vitro model: implications for Parkinson’s disease by Marco Piccoli, Luisa Barbato, Natale Vincenzo Maiorana, Matteo Guidetti, Alessandra Mingione, Francesca Raimondo, Marco Ghirimoldi, Federica Cirillo, Domenico Salerno, Luigi Anastasia, Elisabetta Albi, Marcello Manfredi, Tommaso Bocci, Alberto Priori, Paola Signorelli

Get full text

A Commander-independent function of COMMD3 in endosomal trafficking by Galen T Squiers, Chun Wan, James Gorder, Harrison Puscher, Jingshi Shen

“…Endosomal recycling is a branch of intracellular membrane trafficking that retrieves endocytosed cargo proteins from early and late endosomes to prevent their degradation in lysosomes. …”
Get full text

VPS26A as a Prognostic Biomarker and Therapeutic Target in Liver Hepatocellular Carcinoma: Insights from Comprehensive Bioinformatics Analysis by Hye-Ran Kim, Jongwan Kim

“…Additionally, VPS26A contributes to the molecular architecture governing vesicular trafficking, with potential relevance to diseases involving defects in endosomal transport and autophagy. …”
Get full text

Morphological profiling reveals neuroprotection via mitochondrial uncoupling in human dopaminergic neurons by Vyron Gorgogietas, Amélie Weiss, Loïc Cousin, David Hoffmann, Karen Schmitt, Arnaud Ogier, Peter A. Barbuti, Bruno F. R. Santos, Ibrahim Boussaad, Annika Wittich, Andrea Zaliani, Ole Pless, Rejko Krüger, Peter Sommer, Johannes H. Wilbertz

“…Abstract Parkinson’s disease (PD) involves multiple pathological processes in midbrain dopaminergic (mDA) neurons, including protein degradation defects, vesicular trafficking disruption, endolysosomal dysfunction, mitochondrial issues, and oxidative stress. …”
Get full text