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2141
Prediksi Kelulusan Tepat Waktu Berdasarkan Riwayat Akademik Menggunakan Metode K-Nearest Neighbor
Published 2024-08-01“…Atribut yang dipakai dalam penelitian metode klasifikasi yaitu nama, asal SMA/SMK, wilayah asal SMA/SMK, nilai rata-rata matematika dan lama studi. …”
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2142
Ginseng-derived Nanoparticles Inhibit Lung Cancer Cell Growth by Promoting Macrophage M1 Polarization
Published 2025-02-01“…This study will provide a theoretical basis for further research on fresh ginseng medicine. Methods: The CCK-8 assay was employed to detect the effect of GDNPs on the viability of macrophages (RAW264.7). …”
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2143
Seroprevalence of brucellosis in camels and humans in the Al-Qassim region of Saudi Arabia and its implications for public health
Published 2025-02-01“…The Rose Bengal Test (RBT), Antigen Rapid Brucella Antibody Test (ARBT), indirect enzyme-linked immunosorbent assay (I-ELISA), and complement fixation test (CFT) were used to detect brucellosis in both camels and humans. …”
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2144
Using a Two-Steps Clustering and PCA Analysis for Stratified Chronic Non-Cancer Pain Care: A Retrospective Cross-Sectional Study
Published 2025-02-01“…Those patients showed a significantly different monitoring and basal clinical status. Being older than 65 years old, retired or on medical leave, under opioids and anxiolytic prescription, had a severe impact on daily quality of life without any sex-difference.Conclusion: These clusters based on real-world clinical information might be useful for screening even more where the access to physical exploration is limited. …”
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2145
Dietary steviol glycosides mixture supplementation modulates the gene expression of gut chemoreceptors and enhances the antioxidant capacity in weaned piglets
Published 2025-02-01“…Methods A total of 216 weaned piglets (Duroc × Landrace × Yorkshire, 7.36 ± 0.04 kg body weight) were randomly assigned to 6 groups (6 pens/group with 6 piglets/pen), and were fed with the basal diet supplemented with 0, 100, 150, 200, 250, or 300 mg/kg SGs mixture for 42 days. …”
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2146
Shaoyao Gancao decoction alleviates paclitaxel-induced cognitive impairment by activating PTEN/PI3K/AKT pathway to inhibit NETs formation
Published 2025-02-01“…In addition, SGD could inhibit NETs formation, evidenced by decreasing the level of plasma MPO-DNA complex, as well as MPO and PAD4 expression. Western blotting assay suggested that SGD attenuated the elevated expression of PI3 K, AKT, p-AKT and PKC-α induced by paclitaxel, whereas decreased PTEN expression. …”
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2147
Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
Published 2022-10-01“…Furthermore, T cell senescence induced by mouse tumor and regulatory T (Treg) cells in vitro was determined with multiple markers and assays, including real-time PCR, flow cytometry, and histochemistry staining. …”
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2148
STING agonist-based treatment promotes vascular normalization and tertiary lymphoid structure formation in the therapeutic melanoma microenvironment
Published 2021-02-01“…Treated and control tumors were isolated at various time points to assess transcriptional changes associated with VN and TLS formation via quantitative PCR (qPCR), with corollary immune cell composition changes in isolated tissues determined using flow cytometry and immunofluorescence microscopy. In vitro assays were performed on CD11c+ BMDCs treated with 2.5 µg/mL ADU S-100 or CD11c+ DCs isolated from tumor digests and associated transcriptional changes analyzed via qPCR or profiled using DNA microarrays. …”
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2149
Ecosystem carbon stock variation along forest stand ages: insight from eastern coast mangrove ecosystem of India
Published 2025-02-01“…The correlation analyses revealed that mean stand height (r = 0.87), basal area (r = 0.99), soil nitrogen (r = 0.76), potassium (r = 0.78), and carbon (r = 0.80) were significantly positively correlated with total biomass at p < 0.01. …”
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2150
Large-scale screening of HIV-1 T-cell epitopes restricted by 12 prevalent HLA-A allotypes in Northeast Asia and universal detection of HIV-1-specific CD8+ T cells
Published 2025-02-01“…Furthermore, the HLA-A cross-restriction for each epitope candidate was identified through peptide competitive binding assays using 12 transfected HMy2.CIR cell lines.ResultsA total of 45 epitopes demonstrated high affinity, while 31 epitopes displayed intermediate affinity. …”
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2151
Co-modulation of a circular form of PCDH11Y during neuroendocrine differentiation of prostate cancer
Published 2025-02-01“…Among them, a novel circRNA, circPCDH11Y, was highly upregulated during the transition of LNCaP cells from an epithelial to neuroendocrine phenotype, while its levels remained unchanged in DU145 cells. Functional assays demonstrated that circPCDH11Y plays a role in regulating the expression of key neuroendocrine markers, including synaptophysin (SYP), neuron-specific enolase (ENO2), prostate-specific antigen (PSA), Brain-Specific Homeobox/POU Domain Protein 2 (BRN2) and the linear form of Protocadherin 11 Y-Linked (PCDH11Y). …”
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2152
Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription
Published 2025-02-01“…Bioinformatic analysis, protein coimmunoprecipitation (Co-IP), luciferase assay, cell experiments were performed to reveal the relationship of Celastrol/KAT2B/RBPJ/MCM4 in UCEC. …”
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2153
Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury
Published 2025-02-01“…The sulforhodamine B (SRB) assay of the different fractions against A-549 cell line revealed that the methylene chloride fraction (MCF) had the lowest cell viability at 300 µg/mL (4.54 ± 0.19%). …”
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2154
Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption.
Published 2025-01-01“…<h4>Methodology/principal findings</h4>Cell viability was assessed by CCK-8 assay and the results showed that 200 μg/ml of IIL ESP incubated with Caco-2 cells for 18 h inhibited the Caco-2 cell viability. …”
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2155
Targeting the G-quadruplex as a novel strategy for developing antibiotics against hypervirulent drug-resistant Staphylococcus aureus
Published 2025-02-01“…In vivo reporter followed by coupled in vitro transcription/translation (IVT) assays confirmed the role of mraZ G4 as a target interacting NMM to impose extreme antibacterial activity against both the gram-positive and -negative bacteria. …”
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2156
Contradictory Effect of Lymphocyte Therapy and Prednisolone Therapy on CD3+CD8+CD56+ Natural Killer T Population in Women with Recurrent Spontaneous Abortion
Published 2023-07-01“…Furthermore, the concentration of interferon-gamma (IFN-γ), transforming growth factor-beta (TGF-β) and interleukin-10 (IL-10) was measured quantitatively using the enzyme-linked immunosorbent assay technique. Statistical Analysis Used: Normality and comparisons between study groups were performed by non-parametric unpaired Mann–Whitney, Kruskal–Wallis rank sum test, and one-way ANOVA. …”
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2157
Pendekatan Ensemble untuk Analisis Sentimen Covid19 Menggunakan Pengklasifikasi Soft Voting
Published 2023-04-01“…Ketakutan dan kepanikan massa menyebabkan publik mempublikasikan sentimen di media sosial untuk memberikan tanggapan atau kritik terhadap keputusan yang dibuat oleh negara. …”
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2158
Genetic determinants of skin ageing: a systematic review and meta-analysis of genome-wide association studies and candidate genes
Published 2025-02-01“…Conclusion Despite significant heterogeneity among the included studies and the use of subjective visual methods for phenotype assessment, our review highlights the critical role of fundamental biological processes, such as development and cellular organisation, in skin ageing. …”
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2159
Restoring coronal pre-arthritic alignment in mobile-bearing unicompartmental knee arthroplasty: mid- to long-term outcomes
Published 2025-02-01“…Final follow-up occurred in September 2024, and outcome measures included the visual analogue scale (VAS) score, Hospital for Special Surgery (HSS) score, and Knee Injury and Osteoarthritis Outcome Score (KOOS) subscales for daily living, sports, and survivorship. …”
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2160
Rancang Bangun Aplikasi Mathgeo sebagai Media Pembelajaran Dimensi Tiga Berbasis Mobile
Published 2022-10-01“…This is due to the student’s lack of visualization skills. Moreover, it has not been matched by the use of technology as a learning medium. …”
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