CD276 regulates the immune escape of esophageal squamous cell carcinoma through CXCL1–CXCR2 induced NETs by Yu Liang, Shuang Chen, Zhi Chen, Fang Peng, Qianwen Liu, Gan Xiong, Caihua Zhang, Maosheng Cheng, Rongsong Ling, Demeng Chen, Qimin Zhou

“…Background CD276 (B7-H3), a pivotal immune checkpoint, facilitates tumorigenicity, invasiveness, and metastasis by escaping immune surveillance in a variety of tumors; however, the underlying mechanisms facilitating immune escape in esophageal squamous cell carcinoma (ESCC) remain enigmatic.Methods We investigated the expression of CD276 in ESCC tissues from patients by using immunohistochemistry (IHC) assays. In vivo, we established a 4-nitroquinoline 1-oxide (4NQO)-induced CD276 knockout (CD276wKO) and K14cre; CD276 conditional knockout (CD276cKO) mouse model of ESCC to study the functional role of CD276 in ESCC. …”
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ITGA4 as a potential prognostic and immunotherapeutic biomarker in human cancer and its clinical significance in gastric cancer: an integrated analysis and validation by Jiaxing Zhang, Jiaxing Zhang, Gang Wang, Jie Liu, Futian Tang, Song Wang, Yumin Li, Yumin Li

“…However, its role across different cancer types is not well understood.MethodsUtilizing multi-omics data, we comprehensively evaluated ITGA4’s expression, clinical relevance, diagnostic and prognostic value, functions, mutations, and methylation status, along with its impact on immunity, mismatch repair (MMR), heterogeneity, stemness, immunotherapy responsiveness, and drug resistance in pan-cancer, with partial validation in gastric cancer (GC) using transcriptomic analysis, single-cell data, western blot (WB), wound-healing assay, flow cytometry and immunohistochemistry (IHC). …”
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Factors Associated with Poor Ovarian Reserve in Young Infertile Women: A Hospital-based Cohort Study by Sanghamitra Hazarika, Paapa Dasari, Sairem Mangolnganbi Chanu, Sharbari Basu

“…The sample size was 166 and serum anti-Mullerian hormone (AMH) was estimated by immunoenzymatic assay and expressed in ng/ml. AMH ≤0.99 ng/ml was considered poor ovarian reserve. …”
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Sindrom Makan Malam, Konsumsi Ultra-processed Foods, dan Aktivitas Fisik sebagai Faktor Risiko Gizi Lebih pada Mahasiswa Fakultas Ilmu Kesehatan UPN “Veteran” Jakarta by Raishi Amatullah Hanifa, Firlia Ayu Arini, Utami Wahyuningsih

“…Kriteria inklusi subjek penelitian ini adalah mahasiswa dengan Indeks Massa Tubuh (IMT) > 25 sebagai kasus dan mahasiswa dengan IMT 18,5-25 sebagai kontrol. …”
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Helicobacter pylori SlyD stabilizes TPT1 via hnRNPK and enhances OCT1-mediated CDX2 transcriptional activation to drive gastric intestinal metaplasia by Shuwen Zheng, Yingying Wang, Chuxuan Ni, Rui Guo, Xunan Qiu, Jijun Chen, Lu Wang, Xiaohu Sun, Moye Chen, Yunen Liu, Yuan Yuan, Yuehua Gong

“…Molecular interactions were investigated through co-immunoprecipitation, chromatin immunoprecipitation, and dual-luciferase reporter assays. Additionally, molecular docking was utilized to predict TPT1 inhibitors. …”
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Tissue-friendly dentin treatments as a potential element in revascularization protocol (ex-vivo study) by Hala Fayek Khalil, Nadia Ezz El Din Metwalli, Sara Magdy, Mohamed Shamel

“…Cytotoxicity was assessed using the MTT assay, with optical density measured at the specified times. …”
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LAS CARACTERÍSTICAS Y PERSPECTIVAS FUTURAS DE LA GLOBALIZACIÓN: el caso del sector agro-alimentário by Alessandro Bonanno

“…El objetivo de este artículo es de examinar las características principales del proceso de globalización del sistema agro-alimentario em relación al desarrollo sócio-económico de América Larina. La vasta literatura sobre la globalización está resumida em tres grupos distintos.Los neo-liberalistas radicales argumentan que la globalización representa la receta necessária para adelantar el desarrollo sócio-económico a nível mundial. …”
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Estimation of median LC50 and toxicity of environmentally relevant concentrations of thiram in Labeo rohita by Sana Alam, Gulnaz Afzal, Riaz Hussain, Hafiz Muhammad Ali, Amtul Sami, Rabbiah Manzoor Malik, Raheela Jabeen, Farid Shokry Ataya, Kun Li

“…Oxidative stress parameters; ROS and TBARS were increased significantly (p < 0.05) while antioxidant enzymes (CAT, SOD, POD, GSH) showed a significant (p < 0.05) decrease in the treated groups compared to the control. Moreover, comet assay revealed significant (p < 0.05) DNA damage in the isolated cells of kidneys, heart and brain at higher doses (80 μg/L and 120 μg/L) of thiram that was further confirmed by histo-pathological alterations in these tissues. …”
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Hubungan Kebugaran Jasmani dengan Prestasi Belajar pada Siswa Sekolah Menengah Atas di Semarang by Indriana Rahma Nidya, Apoina Kartini, Suyatno Suyatno

“…Data asupan gizi dikumpulkan menggunakan metode food recall 24 jam. Indeks massa tubuh menurut usia (IMT/U) diperoleh melalui pengukuran berat dan tinggi badan, untuk menentukan status gizi siswa. …”
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Actividad electromiográfica, dolor, discapacidad y percepción de mejoría en dolor cervical crónico en fisioterapia multimodal by Marco Jardim, Diogo Moço, João Sabido, Mariana Correia, Lúcia Domingues

“…Metodología: Un total de 15 pacientes con DCIC participaron en un programa de fisioterapia multimodal de seis semanas. Las evaluaciones basales incluyeron características sociodemográficas e historia clínica de dolor de cuello. …”
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Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression by Tingting Xu, Jianmin Huang, Jiajing Lin, Yuanyuan Liu, Yi Wang, Wenkang Shen, Jianjie He, Shuyun Chen, Xi Zhu, Yuqin Que, Mengting Hu, Yu Chen, Liming Cheng, Honghao He, Xin Liu, Si Liu

“…Additionally, interleukin-11 (IL-11) levels were quantified using a standardized enzyme-linked immunosorbent assay (ELISA). Results Galactosylation and sialylation of IgG decreased mainly in the IgG1 and IgG2 subclasses in GC, with subclass-specific changes in IgG3 and IgG4 galactosylation. …”
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Perancangan User Experience Aplikasi Bimbingan Akademik Mahasiswa FILKOM Menggunakan Metode Human-Centered Design by Farassulthana Azzahra Willary Yaasiin, Herman Tolle, Hanifah Muslimah Az-Zahra

“…The data-based evaluation process will be easier to do if you use a system or application that has the appropriate data visualization. For this reason, it is necessary to design the user experience of the PA Guidance application so that it can be a reference in the development of the system later. …”
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Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…Similarly, the c-reactive protein (CRP), visual analogue scale, and oswestry disability index scores significantly reduced postoperatively. …”
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Ilaser Submucous Destruction in the Treatment of Hemorrhoids by S. A. Frolov, D. V. Vyshegorodtsev, A. M. Kuzminov, Yu. L. Trubacheva, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. N. Ryndin, A. A. Anarbaeva

“…The detected hemorrhoids before the operation, a month after the operation, were not visualized, which persisted after 6 months. The performed transrectal ultrasound examination with spectral-wave dopplerography for up to 6 months allowed to diagnose a persistent decrease in blood flow along the terminal branches of the upper rectal artery compared with preoperative values. …”
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Analisis Efek Augmentasi Dataset dan Fine Tune pada Algoritma Pre-Trained Convolutional Neural Network (CNN) by Theopilus Bayu Sasongko, Haryoko Haryoko, Agit Amrullah

“…In deep learning CNN (Convolutional Neural Network) plays a very important role which is often used to analyze (classify or recognize) visual images. In the era of deep learning models such as the complex Convolutional Neural Network (CNN) as it is today, it has new challenges such as gradient vanishing, overfitting due to dataset limitations, parameter optimization to hardware limitations. …”
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Implementasi Algoritma Fuzzi Mamdani pada Sistem Pakar Menggunakan Software Aplikasi Matlab R2007B, Studi Kasus: Tanaman Hidroponik Selada Air by Okta Purnawirawan, Tri Afirianto

“…In addition, to determine the effect of the masukan variables on the growth and development of watercress plants, it can be visualized using the three-dimensional FIS keluaran surface diagram function. …”
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Influence of spine biomechanics and sagittal balance on the outcome of lumbar discectomy by José Poblete Carrizo, José Poblete Carrizo, Jesús Martínez, Julio González, Alejandra Mosteiro, Ramon Torné, Ramon Torné, Alberto Di Somma, Alberto Di Somma, José Ríos, Joaquim Enseñat, Joaquim Enseñat, Salvador Fuster, Salvador Fuster

“…Follow up of 12 and 24 months after surgery, with radicular and lumbar pain evaluation according to the Visual Analogue Scale (VAS) and Oswestry Disability Index (ODI). …”
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The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

“…**Discussion:** Patients with nAMD or DME were more likely to report severe visual impairment than those without VTRDs, although only those with nAMD were more likely to be diagnosed with vision loss. …”
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Rancang Bangun Alat Pengenal Finger Vein Menggunakan Raspberry Pi dengan Metode Convolutional Neural Network (CNN) by Barlian Henryranu Prasetio, Jevandika, Dahnial Syauqy

“…This research uses a Raspberry Pi 4-based system with the help of IR LEDs and webcams for the acquisition process of finger blood vessel image data, which is expected to be able to carry out the Finger Vein recognition process faster, and the use of the proven Convolutional Neural Network method to produce better accuracy with the Deep Learning process. …”
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Laser Based ¹³C-urea Breath Test in Quantitative Assessment of Bacterial Colonization, Severity of Inflammation and Atrophy in Gastric Mucosa by E. V. Stepanov, V. T. Ivashkin

“…Histological assessment of the state of the gastric mucosa was carried out according to a modified Sydney system with an assessment of morphological changes according to a 4-point visual analog scale (0 to 3+).Results. A total of 525 patients (301 men and 224 women) aged 15–80 years (median 39.8 ± 15.1 years) were examined. 239 (45.5 %) patients were diagnosed with chronic gastritis, chronic duodenitis (including erosive forms). …”
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