Multi-omics reveals that ST6GAL1 promotes colorectal cancer progression through LGALS3BP sialylation by Yuanchao Shi, Zhenzhong Pan, Jingwei Duan, Zexing Wang, Yiliang Fang, Bo Tang, Quanlin Guan

“…To elucidate the protumor mechanisms of ST6GAL1, we performed transcriptomic and N-glycoproteomic analyses and in vitro assays. We found that ST6GAL1 was significantly upregulated in tumor samples than in matched normal samples by analyzing fresh clinical samples from public databases (mean mRNA expression level: tumor vs. normal samples = 0.002712:0.000966, P < 0.05, n = 22). …”
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Examining the Chemical and Optical Properties of Biomass-burning Aerosols and their Impact on Oxidative Potential by Suman Yadav, Taveen Singh Kapoor, Pradnya Vernekar, Harish C. Phuleria

“…Chemical and optical methods were employed to understand PM characteristics, while OP was measured using Dithiothreitol (DTT) assay. The average (± SD) indoor PM2.5, OC, EC, BC, and WSOC during cooking using biomass fuels were 1025 ± 1001, 203 ± 196, 140 ± 133, 112 ± 61, and 130 ± 118 µg m−3, respectively, and the corresponding village outdoor levels were ~12.8 (p = 0.04), 4.9 (p = 0.14), 19.8 (p = 0.09), 23.6 (p = 0.01), and 8.1 (p = 0.12) folds (statistical significance of difference) lower, respectively. …”
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Targeting CXCL8 signaling sensitizes HNSCC to anlotinib by reducing tumor-associated macrophage-derived CLU by Xin Hu, Yikang Ji, Mi Zhang, Zhihui Li, Xinhua Pan, Zhen Zhang, Xu Wang

“…The ability of CLU from TAMs to respond to tumor-derived CXCL8 was assessed using RNA sequencing, siRNA silencing, immunofluorescence and CCK-8 assays. A mouse subcutaneous xenograft model was used to assess the outcomes of nutrition-starvation therapy combined with blockade of CXCL8 signaling. …”
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Ragam Hias Majapahit sebagai Alternatif Desain Motif by Arifatul Khoir, Ningroom Adiani

“…Lambang kerajaan Majapahit dan beberapa ragam hias lain berbentuk geometris dan organik sebagai perwujudan dari buah Maja (asal nama kerajaan Majapahit), banyak ditemui di ragam hias peninggalan kerajaan Majapahit. …”

Bioactive phytochemical compounds characterization, anti-oxidant and anti-microbial activity of the methanol and acetonitrile leaf extracts of Pithecellobium dulce by M. Kiranmayee, K. Riazunnisa

“…The antioxidant activity of extracts was conducted by using DPPH and hydrogen peroxide scavenging activity, and total antioxidant activity was performed by phosphomolybdenum assay. Results: A total of twenty-three compounds were tentatively identified through GC–MS; five of these were associated with the methanolic extracts, while eighteen were with the acetonitrile extract. …”
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Kaposi's sarcoma-associated herpesvirus (KSHV) gB dictates a low-pH endocytotic entry pathway as revealed by a dual-fluorescent virus system and a rhesus monkey rhadinovirus expres... by Shanchuan Liu, Sarah Schlagowski, Anna K Großkopf, Natalia Khizanishvili, Xiaoliang Yang, Scott W Wong, Elina M Guzmán, Marija Backovic, Stefano Scribano, Arne Cordsmeier, Armin Ensser, Alexander S Hahn

“…Together with a hybrid RRV expressing KSHV gB and classical fusion assays, these novel tools identify low vesicle pH as an endocytotic trigger for KSHV membrane fusion.…”
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Epidemiological Survey of Toxoplasmosis among Aborted Women in Garmian district, Kurdistan Region, Iraq by Salar Ibrahim Ali

“…The main aim of this study is to determine prevalence of toxoplasmosis among aborted women in Garmian region by using both Latex Agglutination Test (LAT) and Enzyme Linked Immunosorbent Assay (ELISA). The study was carried out in Kalar General Hospital to detect Toxoplasma antibodies among 350 samples, in which 250 samples were from aborted women and 100 samples were from normal birth women as a control. …”
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Metabolite profile and antioxidant activities of Trikatu, black pepper, Javanese long pepper, and red ginger essential oils by Dewa Ayu Ika Pramitha, Tati Herlina, Iman Permana Maksum, Ari Hardianto, Abd. Wahid Rizaldi Akili, Jalifah Latip

“…Antioxidant activities of TR, BP, JLP, and RG essential oils was determined using the DPPH free radical scavenging assay. Results: The GC–MS analysis of BP, JLP, RG, and TR essential oils revealed the presence of 11 common compound, including linalool, caryophyllene, and beta-bisabolene. …”
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Development of highly bioactive long-acting recombinant porcine FSH for batch production management of sows by Jiawei Zhang, Lei Shi, Xiaorong Zhong, Yunhe Bai, Jun Dou, Lu Zhang, Xiaochao Shi, Bingchun Wu, Zemin Tan, Lin Yan, Jinku Yu, Jingru Zhang, Guo Han, Jiansheng Xiong, Hua Zhang, Xingyuan Cao, Haoshu Luo

“…Through ovarian weight gain, superovulation and fertility testing assays, our results revealed that a single rpFSH-pFc treatment could effectively promote follicular development and maturation in vivo. …”
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Effect of noninvasive respiratory support on interstitial lung disease with acute respiratory failure: A systematic review and meta-analysis by Natthawan Sanguanwong, Nattawat Jantarangsi, Jinjuta Ngeyvijit, Natthida Owattanapanich, Vorakamol Phoophiboon

“…# Background Primary studies have demonstrated the effectiveness of noninvasive respiratory supports, including noninvasive positive pressure ventilation (NIPPV) and high flow nasal cannula (HFNC), for improving oxygenation and ventilation in patients with interstitial lung diseases (ILDs) and acute respiratory failure (ARF). …”
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Inhibition of Ultraviolet B-induced Apoptosis in Fibroblasts by Human Umbilical Cord Blood Mesenchymal Stem Cell Conditioned Media via the Phosphatidylinositol-3-Kinase/Akt Pathway by Ferry Sandra, Dian Andriani Ratna Dewi, I Nyoman Mantik Astawa, Wimpie Pangkahila, Angliana Chouw, Maria Celinna, Nurrani Mustika Dewi

“…Subsequently, the cells were analyzed using sub-G1, immunofluorescence, and immunoblotting assays. One-way analysis of variance (ANOVA) was used for data analysis, followed by Tukey’s honest significant difference (HSD) test or the Kruskal-Wallis test, followed by the Dunn-Bonferroni test using IBM SPSS Statistics software version 21. …”
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Epidemiology of Non-Melanoma Skin Cancer Patients Attending at Hiwa Hospital in Sulaimani City, Iraq by Bushra Mohammed Ali, Hiwa Abas Ahmed

“…About (64%) of cases had squamous cell carcinoma and (36%) had basal cell carcinoma. Most of the cases had family history of skin cancer (11.4%), and 44 (62.9%) of cases had a history of more than 4 hours exposure to sun in a day and 36 (51.4%) of cases were with normal BMI. …”
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MULHERES JOVENS, SEXUALIDADE E DUPLA PROTEÇÃO EM UMA COMUNIDADE RURAL DE CARUARU, PERNAMBUCO by Marion Teodósio de Quadros, Karla Galvão Adrião, Maria Julia Carvalho de Melo

“…Esse trabalho é resultado de pesquisa qualitativa relativa à vivência de mulheres jovens, com práticas heterossexuais, de uma comunidade rural de Caruaru - Pernambuco, mediante a reconstrução, identificação e percepção dos roteiros sexuais e dos sistemas que regem a sexualidade das jovens, associando-os à dupla proteção, que significa prevenção das infecções sexualmente transmissíveis/HIV e da gravidez não desejada de forma simultânea, sendo uma prática que implica a concordância e envolvimento de um casal heterossexual. Como metodologia foi utilizado o estudo de trajetórias sexuais e reprodutivas. …”
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Genome-wide association study of the antibody response to <i>Corynebacterium pseudotuberculosis</i> in sheep by J. Kyselová, L. Tichý, J. Marková, A. Gurgul, Z. Sztankóová, K. Vališ, S. Šlosárková, K. Kavanová, M. Beinhauerová, T. Szmatola, T. Szmatola

“…The sheep were classified into healthy and diseased groups based on two different commercial enzyme-linked immunosorbent assay (ELISA) serological antigen tests. Genomic DNA was genotyped with the GeneSeek^® Genomic Profiler™ Ovine 50 K, and 41 301 markers were used for the genome-wide association analysis (GWAS). …”
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Hubungan Menu Anxiety, Pemilihan Makanan, dan Kebiasaan Makan pada Status Gizi Generasi Z di Cinere, Depok by Khoirul Anwar, Fathiarica Sharifa Putri, Dadi Hidayat Maskar

“…Terdapat hubungan antara frekuensi makan diluar (eating out) dengan status gizi subjek berdasarkan indeks massa tubuh berdasarkan umur (IMT/U) (p-value=0,019; r=0,252), tetapi tidak terdapat hubungan signifikan antara kebiasaan makan buah, sayur, snack manis, dan minuman manis dengan status gizi  (p-value>0,05) . …”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…We trained a model to predict 1-year progression-free survival (PFS) using pathological images (H&amp;E, programmed cell death-ligand 1 (PD-L1), and double immunohistochemical assay (cluster of differentiation 8 (CD8) and forkhead box P3 (FoxP3)) and patient information. …”
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The value of inflammation-related indicators in chemotherapy efficacy and disease-free survival of triple-negative breast cancer by Jie Zhu, Jiale Cheng, Yuyuan Ma, Ying Wang, Zhonghua Zou, Wenjie Wang, Haihua Shi, You Meng

“…Levels of interleukin-6 (IL-6) were detected by enzyme-linked immunosorbent assays (ELISAs). Platelet-to-lymphocyte ratio (PLR) and immune inflammatory index (SII) were obtained from blood routine. …”
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Utilisation of an in vivo malaria model to provide functional proof for RhopH1/CLAG essentiality and conserved orthology with P. falciparum by Mitchell L. Trickey, Mrittika Chowdury, Georgina Bramwell, Natalie A. Counihan, Tania F. de Koning-Ward

“…The inducible clagX knockout in conjunction with a guanidinium chloride induced-haemolysis assay to assess NPP function provided the first evidence of CLAG essentiality to Plasmodium survival and NPP function in an in vivo model of infection. …”
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Cytotoxicity and Exposure Assessment of PM2.5 in a Residential Home during COVID-19 Lockdown by Ummi Sabariah Mahamud, Armania Nurdin, Eliani Ezani

“…PM2.5 samples were then extracted using methanol. MTT assay determined the cytotoxic activity of extracted indoor and outdoor PM2.5 treated at different concentrations (25–200 µg mL−1) on human lung cells (MRC-5) at a 24-hour incubation period. …”
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Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer by Yuh-Shyan Tsai, Yeong-Chin Jou, Ian Seng Cheong, Hsiu-Ting Tung, Lin-Nei Hsu, Hsin-Tzu Tsai, Tzong-Shin Tzai

“…Unlike MIR-205, a known tumor suppressor gene in prostate cancer, gene set enrichment analysis revealed that higher MIR-5010 expression was linked to increased Nrf-2 downstream signaling (enriched score: 0.35; p = 0.17). In vitro assays in prostate cancer cells showed that DEHP enhanced Nrf-2 protein expression and its downstream signaling molecules (i.e., SOD2, Heme oxygenase-1, and EGR-1) while increasing GDF15 mRNA expression via EGR-1 regulation in a dose- and time-dependent manner. …”
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