Clinical, genomic, and histopathologic diversity in cerebral cavernous malformations by Jian Ren, Daochao Wang, Leiming Wang, Chendan Jiang, An Tian, Ziwei Cui, Yeqing Ren, Lisong Bian, Gao Zeng, Guolu Meng, Yongzhi Shan, Jiantao Liang, Xinru Xiao, Jie Tang, Yukui Wei, Chuan He, Liyong Sun, Yongjie Ma, Jiaxing Yu, Guilin Li, Ming Ye, Peng Hu, Jingwei Li, Ye Li, Lijian Niu, Qianwen Li, Feng Ling, Jan-Karl Burkhardt, Hongqi Zhang, Tao Hong

“…Histopathologically, lesions with PIK3CA mutations displayed cyst walls, pS6-positive dilated capillaries, and fresh blood cells, while MAP3K3 and double mutation lesions exhibited classic CCM pathology with SMA-positive and KLF4-positive vessels, collagen, and calcification. PIK3CA lesions had fewer KLF4-positive cells than double mutations lesions (P < 0.001), and EndMT (SMA-positive) cells compared to double mutation lesions (P < 0.05) and MAP3K3 mutations (P < 0.001), with more pS6 compared to MAP3K3 mutations (P < 0.05). …”
Get full text

Using Dose-Effect Relationship for Optimising Systemic Corticosteroid Dosage in Treatment of Inflammatory Bowel Diseases by O. P. Alekseeva, S. V. Krishtopenko, A. A. Alekseeva

“…The method realises an adequate statistical transformation of primary clinical data in form of a quantitative expression of factual doses and registered alternative responses established with endpoint criteria into a visual efficacy function graph suitable for downstream analyses. …”
Get full text

Comparative Evaluation of Regain of Consciousness in Dexmedetomidine–Propofol versus Ketamine–Propofol in the Pediatric Cardiac Catheterization Procedure under Sedation using BIS M... by Priya Banga, Sunder L. Negi, Banashree Mandal, Parag Barwad, Kulbhushan Saini, Krishna P. Gourav

“…Propofol top of 1 mg/kg was administered when the BIS value became more than 80 or when the child moved during the femoral vessel puncture or when the child moved during the procedure. …”
Get full text

Quality of Life with Late-Onset Pompe Disease: Qualitative Interviews and General Public Utility Estimation in the United Kingdom by Lena Hubig, Anna-Katrine Sussex, Alasdair MacCulloch, Derralynn Hughes, Ryan Graham, Liz Morris, Syed Raza, Andrew J. Lloyd, Amanda Sowinski, Katy Gallop

“…Participants rated the health states using the EQ-5D-5L, visual analogue scale, and time trade-off interviews. …”
Get full text

Development and validation of a novel bleeding risk prediction tool for aspirin users with a low body mass index by Lu Yifang, Lei Wanlin, Wang Maofeng

“…These variables were integrated into a visually represented nomogram. The model exhibited an AUC of 0.832 (95% CI: 0.788–0.875) in the training dataset and 0.775 (95% CI: 0.698–0.853) in the test dataset, indicating excellent discriminatory performance. …”
Get full text

Long-term effects of orthognathic surgery on masticatory function in individuals with cleft lip and palate: A prospective study by Patricia Martins Bueno, Paulo Alceu Kiemle Trindade, Laís Hollara Medeiros, Leide Vilma Fidélis da Silva, Ivy Kiemle Trindade-Suedam

“…Three variables were evaluated: 1) Bite Force (BF) (measured in Newtons – N) presented as the average of the bite force from the right and left molars (x‾ RM + LM), using a gnathodynamometer (IDDK Kratos), 2) Masticatory Efficiency (ME) (ranging from 0 to 1, with values closer to 1 indicating poorer efficiency), assessed through a dual-color masticatory gum test analyzed visually and optoelectronically (ViewGum©), and 3) Masticatory Capacity (MC): patient-reported ability to chew, rated on a two-point scale (P/R = poor to reasonable, G/O = good to optimal). …”
Get full text

Effect of the cervical and thoracic “Daoyin” training on posture and pulmonary function in patients with upper crossed syndrome: a randomized controlled trial by Yue Guo, Ming Li, Chaowei Xie, Xiaoyan Liu, Yushan Chen, Jun Yang, Yuxue Wu, Shaoqing Chen, Shizhong Wang, Jianping Lin

“…These measurements were conducted using photogrammetry, visual analog scale (VAS), Neck Disability Index (NDI), pulmonary function, cervical range of motion test and Self-rating Anxiety Scale (SAS), respectively. …”
Get full text

Radiological assessment of cup anteversion with a novel 3D-printed highly-porous titanium dual mobility cup by Nicole Puteo, Edoardo Matteo Valentino, Vittorio Davidoni, Domenico Tigani

“…Abstract Background Cup anteversion after primary total hip arthroplasty (THA) with monobloc dual mobility cups (DMC) is difficult to measure on anterior-posterior (AP) pelvic radiographs because of the implant radiopacity and cup design which do not allow for an accurate visualization of the radiographic projection of the cup equatorial rim and the femoral head. …”
Get full text

A dehazing and enhancement algorithm for heterogeneous images of underground mining environments in coal mines by Xuhui ZHANG, Yanbin XIE, Wenjuan YANG, Chao ZHANG, Jicheng WAN, Zheng DONG, Yanqun WANG, Jie JIANG, Long LI

“…The results indicate that compared to the above novel and excellent algorithms in terms of their optimal indicators, the proposed algorithm exhibited that: (1) The average gradients were approximately twice those obtained by CEEF, suggesting elevated image clarity. (2) The average information entropy decreased by approximately 1% compared to that of MRP, implying more information preserved. (3) The standard deviation increased by approximately 6% on average compared to OSFD, representing improved image contrast. (4) The average fog aware density evaluator (FADE) value by approximately 23% compared to CEEF, implying an effective reduction in the haze Therefore, the proposed algorithm can effectively improve the visual effects and quality of blurred images of underground mining environments in coal mines, exhibiting high utility in engineering.…”
Get full text

Comparative analysis of ocular biometrics using spectral domain optical coherence tomography with Purkinje image and optic nerve head alignments in mice by Ying Hon Sze, Bing Zuo, Da Qian Lu, King Kit Li, Dennis Yan Yin Tse, Qian Zhao, Thomas Chuen Lam

“…Results Mice developed hyperopic ametropia under normal visual conditions. The photorefractor measured a technical variation of 3.9 D (95% CI, n = 170, triplicates). …”
Get full text

Advantages of alginate and PPI combination in relief of heartburn and regurgitation during the first days of treatment of gastroesophageal reflux disease by D. S. Bordin, O. B. Yanova, O. I. Berezina, Ye. V. Treyman

“…General well-being was evaluated by visual-analog scale (VAS) prior to therapy, at the 7th and 14th days of treatment. …”
Get full text

EVALUATION OF SMARTNESS OF THE TOURISM DESTINATION WEBSITES OF THE KLAIPEDA REGION by Julius Ramanauskas, Šarūnas Banevičius, Putinas Bielskis

“…However, accessibility for people with hearing or visual impairments remains a significant challenge (4.41). …”
Get full text

The Opportunity of Using Diode Laser with the Length of 1940 nm in the Treatment of Hemorrhoids by S. A. Frolov, A. M. Kuzminov, D. V. Vyshegorodtsev, O. A. Mainovskaya, Yu. L. Trubacheva, O. Yu. Fomenko, V. Yu. Korolik, I. S. Bogormistrov, I. A. Mukhin, A. M. Battalova, E. M. Bogdanova

“…Transrectal ultrasound with Dopplerography was performed, which made it possible to diagnose a 2–3-fold decrease in blood flow along the terminal branches of the upper rectal artery, and internal hemorrhoids determined earlier, before surgery, were not visualized already 1 month after surgery. According to sphincterometry, no violations of anal retention function were detected in all 28 patients.Conclusion. …”
Get full text

Sistem Monitoring Gelombang Osilometrik Menggunakan Arduino dan Smartphone by Muhammad Fawwaz Dynoeputra Isnandar, Barlian Henryranu Prasetio, Mochammad Hannats Hanafi Ichsan

“…Abstract Blood pressure occures when the arteries of blood vessels is pumped by the heart to the whole body. …”
Get full text

Validação transcultural da versão moçambicana da escala de autoeficácia em Educação Física inclusiva by Leonor Picardo, Maria João Campos, José Pedro Ferreira

“…Os valores de Alpha de Cronbach de cada uma das variáveis observadas variaram entre 0,786 e 0,823 para Deficiência Intelectual (DI), entre 0,732 e 0,826 para Deficiência Física (DF) e entre 0,729 e 0,847 para Deficiência Visual (DV), demonstrando valores bons de consistência interna. …”
Get full text

MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism by Ni Mo, Chuyang Tai, Yang Yang, Cong Ling, Baoyu Zhang, Lei Wei, Cian Yao, Hui Wang, Chuan Chen

“…Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
Get full text

Effectiveness of Retail Promotions in the Green Industry by Age Group: A Case Study by Hayk Khachatryan, Alicia Rihn

“…Specifically, similarities and differences between younger and older consumers and their visual attention to point-of-sale (POS) information is explored.  …”
Get full text

Assessing learning, behaviour, and stress level in goats while testing a virtual fencing training protocol by L. Wilms, D. Hamidi, C.H.U. Lüntzel, M. Hamidi, M. Komainda, R. Palme, J. Isselstein, S. Waiblinger, M. Egerbacher

“…The VF treatment involved a virtual fence at one side of the paddock, to which the goats were gradually introduced over the first 2 days (additional physical fence or posts as visual support). On day eight, the grazing areas were enlarged by shifting the virtual fence and one side of the physical fencing treatment. …”
Get full text

Psychological and autonomous nervous system features of functional gastric dyspepsia and irritable bowel syndrome, duloxetine treatment efficacy by A. P. Pogromov, G. M. Dyukova, M. L. Leonova

“…., 1998), for evaluation of pain phenomena of various location – visual-analog scale.Results. At comparative analysis of gastroenterological symptoms in FGID and OGID patients in general it was revealed, that for majority of them no essential difference between organic and functional groups exits. …”
Get full text

Estimating the Health-Related Quality of Life Benefit of Prophylactic Treatment for COVID-19 in Immunocompromised People: A Multimethod Valuation Study by Katy Gallop, Rebekah Hall, Michael Watt, Daniel Squirrell, Neil Branscombe, Sofie Arnetop, Andrew Lloyd

“…Vignettes were valued by a general population sample (N = 100) using a visual analog scale (VAS), time trade-off (TTO), and EQ-5D-5L. …”
Get full text