Estimation of cytoprotective effect of bismuth tripotassium dicitrate on gastric mucosa at <i>H. pylori</i> eradication and long-term drug intake by A. V. Kononov, S. I. Mozgovoi, L. B. Rybkina, S. S. Bunova, A. G. Shimanskaya

“…Detection of the damaged DNA in SM generative zone cells by immunehistochemical assay of P53-positive cells allows to establish significant decrease of their number in biopsies of the patients, who received the drug after cessation of eradication therapy that can be considered as a marker of protective effect for generative zone cells — cytoprotective «target» of bismuth drug.…”
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Assessment of point-of-care quantitative serum canine pancreatic lipase testing for diagnosing acute pancreatitis in dogs by Pin-Chen Liu, Pin-Chen Liu, Kendy Tzu-yun Teng, Kendy Tzu-yun Teng, Tsia-Lu Lin, Chi-Hsuan Sung, Tsun-Li Cheng, Chi-Chung Chou, Chi-Chung Chou

“…The intra-class correlation coefficient (ICC) was used for statistical analysis to assess the agreement between assays and the internists’ consensus score.ResultsDogs with suspected acute pancreatitis had significantly higher serum Vcheck CPL (median: 843 μg/L, range: 77–2001, p &lt; 0.0001) than healthy control dogs (median: 94 μg/L, range: 49–294). …”
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Genome-wide identification, characterization, and expression analysis of BZR transcription factor family in Gerbera hybrida by Qishan Luo, Gan Huang, Xiaohui Lin, Xiaojing Wang, Yaqin Wang

“…Subcellular localization analysis indicated nuclear localization for GhBEH1 and GhBEH2, while the remaining five genes exhibited dual localization in the nucleus and cytoplasm. The transactivation assay indicated that GhBEH1 and GhBEH2 may function as transcriptional repressors, contrasting with the transcriptional activation observed for the other five genes. …”
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The emerging role of glycine receptor α2 subunit defects in neurodevelopmental disorders by Sean D. Fraser, Sean D. Fraser, Robert J. Harvey, Robert J. Harvey

“…Genetic inactivation of GlyR α2 impairs the capacity of apical progenitors to generate basal progenitors, resulting in an overall reduction of projection neurons in the cerebral cortex. …”
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GGCT participates in the malignant process of hepatocellular cancer cells by regulating the PTEN/PI3K/AKT pathway through binding to EZH2 by Junbo He, Liangzhi Wang, Mengjia Lv, Yiming Yuan

“…CCK-8, EdU, and wound healing, together with transwell and western blot assays were adopted to assess the capabilities of cells to proliferate, migrate, invade, and epithelial-mesenchymal transition (EMT). …”
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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

“…Surface plasmon resonance and molecular docking analyses revealed that Kae directly binds to ATF4, while proteome microarray and co-immunoprecipitation assays demonstrated that ATF4 interacts with ACSL4 in HAECs. …”
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Serum amylase level measurement in acute abdominal pain by Taher Abdullah Hawramy, Dara Ahmed Mohammed, Botan H. Tahir

“…All non-traumatic adult patients with acute abdominal pain within twenty-four hours before admission were included and serum amylase levels were measured on admission using Enzyme-Linked Immunosorbent Assay (ELISA) available at (ED). Overall, 68 patients were included, with mean age of 45.9 years over the aforementioned time period, 44 females (64.7%) and 24 males (35.3%), of which 37 patients had normal serum amylase level (14 male and 23 female patients), defined as levels between (35 IU/L-115 IU/L) by the laboratory (ELISA) device used for all the tests, while the other 31 patients (10 males and 21 females) had high serum amylase levels due to different disease processes, the most common two with equal frequencies were acute calculous cholecystitis (41.9%) and acute pancreatitis (41.9%).   …”
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The prognostic value of ferritinemia level in patients with chronic hepatitis C by N. C. Sargsyants, E. H. Grigoryan

“…The level of ferritin was determined in 67 patients with CHC by two solid-phase sandwich immunoenzymatic assays. In 32 patients, who received PEG-IFN α-2a and RBV, it was determined on starting point, on the 12th week and after termination of therapy. …”
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An unbiased cell morphology-based screen for new, biologically active small molecules. by Masahiro Tanaka, Raynard Bateman, Daniel Rauh, Eugeni Vaisberg, Shyam Ramachandani, Chao Zhang, Kirk C Hansen, Alma L Burlingame, Jay K Trautman, Kevan M Shokat, Cynthia L Adams

“…We have implemented an unbiased cell morphology-based screen to identify small-molecule modulators of cellular processes using the Cytometrix (TM) automated imaging and analysis system. This assay format provides unbiased analysis of morphological effects induced by small molecules by capturing phenotypic readouts of most known classes of pharmacological agents and has the potential to read out pathways for which little is known. …”
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Faktor yang Mempengaruhi Tekanan Darah pada Remaja SMA di Depok, Jawa Barat by Nesa Trista, Nur Intania Sofianita, A'immatul Fauziyah

“…Riwayat hipertensi keluarga ditentukan berdasarkan adanya anggota keluarga yang mengalami hipertensi, status gizi diukur menggunakan Indeks Massa Tubuh berdasarkan Permenkes 2020, dan tingkat stres dinilai menggunakan PSS (Perceived Stress Scale). …”
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Adjunctive diagnostic tool for histopathological classification of congenital mesoblastic nephroma based in molecular genetic findings by Hiroshi Hamada, Kenichi Kohashi, Takeshi Iwasaki, Mikiko Hashisako, Yuko Hino, Masahiro Fukuhara, Amane Kamouchi, Naonori Kawakubo, Tatsuro Tajiri, Yoshinao Oda

“…Comprehensive mRNA analysis was performed using the nCounter® Gene Expression Assay. Principal component analysis (PCA) was performed based on the gene expression levels. …”
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Molecular Identification of Fusarium proliferatum from toenails: A case report by Sazan Jamal Gharib, Nawroz Abdul-razzak Tahir

“…To study of these fungi as the true causative agents of nail infection, we describe a PCR/sequencing assay to confirm routinely diagnosis of the infecting fungi in this case with toenail Onychomycosis. …”
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MyD88 inhibitor TJ-M2010-5 alleviates spleen impairment and inflammation by inhibiting the PI3K/miR-136-5p/AKT3 pathway in the early infection of Trichinella spiralis by Huifang Bai, Qianqian Dang, Guoliang Chen, Lingfeng Xie, Saining Wang, Ning Jiang, Xiaoxia Wu, Shuyan Zhang, Xuelin Wang

“…A dual-luciferase reporter assay further revealed that miR-136-5p is involved in the TJ-M2010-5 treatment by targeting AKT3. …”
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Sophocarpine inhibits the proliferation and induces apoptosis of glioblastoma cells through regulating the miR-21/PTEN/PI3K/AKT axis by Feng Si, Qian Wang, Fei Chen, Xiangdong Lu

“…Cell cycle and cell apoptosis were determined by flow cytometry assay. The results indicated that SC inhibited proliferation and induced apoptosis of LN229 and SF539 cells in a dose-dependent manner. …”
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Comparing The Viral Load of Severe Acute Respiratory Syndrome Coronavirus 2 in Different Human Specimens by Ali Hattem Hussain

“…Nasopharyngeal swab has the highest positivity rate (90.5%) for viral load detection followed by Bronchoalveolar lavage, nasal swab, nasopharyngeal aspirate, throat swab and sputum. …”
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Risk of Cirrhosis in Patients with Non-alcoholic Fatty Liver Disease and Previous Viral Hepatitis B by S. N. Batskikh, E. V. Vinnitskaya, E. S. Sbikina, Zh. V. Borunova, A. S. Dorofeev, Yu. G. Sandler

“…Liver biopsy was performed in 35 patients (31.8%), other patients had transient elastography with steatometry and/or a serum FibroMax™ assay (FibroTest+SteatoTest+NashTest).Results. In 85 patients, liver fibrosis was scored F0-F2 with METAVIR, 25 persons had severe fibrosis (F4 in 23, F3 in 2). …”
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Synergistic toxicity of nanoplastics and Helicobacter pylori on digestive system in mice by Xiaolin Zhang, Yunqing Wang, Xiaohan Tong, Boqing Li, Sisi Liu, Yingzi Cui, Wenke Wang, Zhiqin Li, Chunlei Ma, Ying Zhang

“…Enzyme-linked immunosorbent assays quantified interleukin-6 (IL-6), malondialdehyde (MDA), triglyceride (TG), and lactate dehydrogenase (LDH) levels, which significantly increased in co-exposure groups compared to single-exposure groups (P < 0.05). …”
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Ginkgetin delays the progression of osteoarthritis by inhibiting the NF-κB and MAPK signaling pathways by Liang Zhu, Yanchi Bi, Ting Liang, Po Zhang, Xiao Xiao, Tengbo Yu

“…GK's anti-inflammatory and antioxidative effects were comprehensively assessed via MTT assay, western blot, cell immunofluorescence, ELISA, and transcriptome sequencing. …”
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PCR-based detection of Botryosphaeria canker pathogens in fig trees by Mahdiyeh Ghaedi, Zeinab Bolboli, Hamed Negahban, Reza Mostowfizadeh-Ghalamfarsa

“…In our study, we developed a PCR assay using three carefully selected primer pairs based on sequence differences in two protein-coding genes, β-tubulin and RNA polymerase II. …”
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Integrating whole-genome re-sequencing and transcriptome data to reveal the molecular mechanism of TBX5 gene regulating feathered feet in Guangxi native chickens by Zhuliang Yang, Yongcui Liu, Jintang Luo, Cong Xiao, Hong Yuan, Wenya Du, Xiurong Yang

“…EdU fluorescence staining, flow cytometry, and migration assays demonstrated that moderate expression of TBX5 can promote the proliferation and migration of dermal fibroblasts, while TBX5 interference produced opposite results. …”
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