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3441
‘Every Touch Point Is an Opportunity’: Tobacco Control Experts' Views on How to Implement Smoking Cessation Interventions Within an Australian Lung Cancer Screening Program
Published 2025-05-01“…We sought perspectives from tobacco control/smoking cessation experts on optimally implementing smoking cessation interventions in an Australian LCS program. Methods Recruitment was via maximum variation and snowball sampling in 2022. …”
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3442
Plasmodium falciparum and Schistosoma mansoni coinfections among the general population in Ethiopia: a systematic review and meta-analysis
Published 2024-12-01“…These results direct future research, integrated control strategy design, and resource allocation to successfully manage Ethiopia’s combined burden of malaria and schistosomiasis.…”
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3443
Population-specific genetic differences of acute coronary syndrome in Han and Uyghur Chinese
Published 2025-08-01“…This study explores the genetic variation associated with ACS subtypes in the Han and Uyghur Chinese populations to support the development of precision medicine approaches tailored to ethnic-specific genetic backgrounds.MethodsA total of 985 ACS patients (668 Han and 317 Uyghur Chinese) representing different ACS subtypes were enrolled. …”
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3444
Multi-omics analysis reveals immunosuppression in oesophageal squamous cell carcinoma induced by creatine accumulation and HK3 deficiency
Published 2025-05-01“…Importantly, ESCC patients were stratified into three subtypes (S1, S2, and S3) on the basis of integrated metabolomic and proteomic data. A robust subtype prediction model was developed and validated across two independent cohorts. …”
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3445
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3446
Effect of liver biopsy size on MASLD fibrosis assessment by second-harmonic generation/two-photon excitation fluorescence microscopy
Published 2025-08-01“…Second-harmonic generation/two-photon excitation fluorescence (SHG/TPEF) microscopy images unstained tissue sections and, when integrated with artificial intelligence models, generates a continuous fibrosis value (qFibrosis) and ordinal qFibrosis stage. …”
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3447
Identification and validation of reference genes for qPCR of Pseudomonas aeruginosa L10 under varying n-hexadecane concentrations
Published 2025-07-01“…RefFinder provides a comprehensive assessment of reference gene stability by integrating four methods. The results indicated that among the reference genes of P. aeruginosa L10 cultured under various concentrations of n-hexadecane stress, anr had the highest Ct value and expression abundance, while tipA had the lowest. …”
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3448
Factors associated with clinical antimicrobial resistance in China: a nationwide analysis
Published 2025-04-01“…Despite improvements in decreasing AMR, future initiatives should consider integrated strategies to control PM2.5 and other factors simultaneously to decrease AMR. …”
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3449
Trend of thyroid cancer incidence in China, 1992-2021: a Joinpoint regression and age-period-cohort analysis
Published 2025-07-01“…Auto regressive integrated moving average (ARIMA) model was applied to predict the incidence of thyroid cancer in China in the next 20 years. …”
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3450
The clinical aspects ot the sulphonylurea compounds from the position of the cardioprotective approach at patient with type 2 diabetes, using glucocardiomonitoring
Published 2022-10-01“…Meanwhile the synchronized glucocardiomonitoring allowed to providing the accurate information about the cardiometabolic status of patients with T2DM.AIMS: Using the professional glucocardiomonitoring for T2DM-SU patients to investigate the relation between the glycemic variability, integral glycemic parameters and proarrhythmogenic cardiovascular events and the long-term cardiovascular outcomes.MATERIALS AND METHODS: In the observational (randomised for inclusion of patients) controlled trial the SU-patients with the T2DM duration 9,8±6,6 years were included, whom the professional glucocardiomonitoring had been made during 5 days and then the fatal and non-fatal cardiovascular events had been investigated during 5 years. …”
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3451
Malignant epithelial cell marker–driven risk signature enables precise stratification in esophageal cancer
Published 2025-05-01“…Single-cell RNA sequencing (scRNA-seq) provides new perspectives on the cellular makeup and conditions in tumor tissues, with promising implications for functional classification and personalized therapeutic strategies in esophageal cancer.MethodsIn this study, we integrated scRNA-seq data with bulk RNA-seq profiles from esophageal cancer tissues to construct a comprehensive cellular atlas, focusing on the transcriptional characteristics of epithelial cells. …”
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3452
Feasibility study of a domestic fully automated NAT system for blood screening in blood donors
Published 2025-07-01“…[Objective] To validate the analytical performance, operational performance, and process control measures of a domestic fully automatic nucleic acid testing (NAT) system, thereby ensuring an efficient and orderly blood screening workflow. [Methods] The concordance rate and sensitivity of WanTag-Vortex Plus system were verified using WHO standard reference panels of HIV-1, HCV and HBV, while precision was assessed using weak positive samples of HIV-1, HCV and HBV. …”
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3453
Assessing Dynamic Cognitive Function in the Daily Lives of Youths With and Without Type 1 Diabetes: Usability Study
Published 2025-02-01“…ObjectiveBefore we can assess this relationship, we need to determine the feasibility of measuring cognition in youths in daily life and determine the plausibility of obtaining glucose variation with CGM to be integrated with real-time cognition measures. …”
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3454
Entomological Surveillance of Aedes mosquitoes, vectors of arboviruses in a peri-urban area of Yaounde, Centre, Cameroon
Published 2025-03-01“…It is important to measure variation in their population to predict the environmental conditions promoting their development. …”
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3455
Protocol: the International Milk Composition (IMiC) Consortium - a harmonized secondary analysis of human milk from four studies
Published 2025-06-01“…Multi-modal machine learning methods (extreme gradient boosting with late fusion and two-layered cross-validation) will be applied to predict infant growth and identify determinants of HM variation. …”
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3456
Modeling healthcare resource dynamics and its application based on interregional population mobility
Published 2025-07-01“…In the event of an infectious disease outbreak, this model can be integrated into a regionally unified platform for healthcare resource allocation. …”
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3457
Effect of Zinc Nano Oxide on the Quality of Turkey Sperm in Liquid State
Published 2025-03-01“…Zinc oxide nanoparticles improve acrosomal membrane integrity, preserve membrane health, enhance acrosomal function, and positively affect mitochondrial performance and its functional integrity Methods: Semen samples were collected twice weekly for five weeks from 18 Bronze turkeys. …”
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3458
Global Methane Budget 2000–2020
Published 2025-05-01“…FLUXNET-CH<span class="inline-formula"><sub>4</sub></span> measurements, urban-scale monitoring, satellite imagery with pointing capabilities) to regional scales (surface networks and global remote sensing measurements from satellites) to constrain both bottom-up models and atmospheric inversions; (iv) improvements of transport models and the representation of photochemical sinks in top-down inversions; and (v) integration of 3D variational inversion systems using isotopic and/or co-emitted species such as ethane as well as information in the bottom-up inventories on anthropogenic super-emitters detected by remote sensing (mainly oil and gas sector but also coal, agriculture, and landfills) to improve source partitioning.…”
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3459
Mapping near-real-time soil moisture dynamics over Tasmania with transfer learning
Published 2025-04-01“…The fine-resolution soil moisture maps captured the detailed landscape variation as well as temporal variation according to four distinct seasons in Tasmania. …”
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The alteration of IL-17 signaling pathway in bipolar disorder: a preliminary study with transcriptomic perspective
Published 2025-06-01“…This study aims to explore global mRNA expression in Peripheral blood white cells (PBMC) of BD patients.MethodsWe analyzed whole-genome gene expression profiles from PBMC of 12 BD states-manic (BD-M), 12 BD states-depressive (BD-D), and 12 matched healthy controls (HC) using microarrays. …”
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